KEGG   PATHWAY: sdur00061
Entry
sdur00061                   Pathway                                
Name
Fatty acid biosynthesis - Streptomyces durmitorensis
Class
Metabolism; Lipid metabolism
Pathway map
sdur00061  Fatty acid biosynthesis
sdur00061

Module
sdur_M00086  beta-Oxidation, acyl-CoA synthesis [PATH:sdur00061]
Other DBs
GO: 0006633
Organism
Streptomyces durmitorensis [GN:sdur]
Gene
M4V62_17105  ATP-grasp domain-containing protein [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
M4V62_28895  ACP S-malonyltransferase [KO:K00645] [EC:2.3.1.39]
M4V62_39460  beta-ketoacyl-ACP synthase 3 [KO:K00648] [EC:2.3.1.180]
M4V62_43455  ketoacyl-ACP synthase III [KO:K00648] [EC:2.3.1.180]
M4V62_00110  ketoacyl-ACP synthase III family protein [KO:K00648] [EC:2.3.1.180]
M4V62_08670  ketoacyl-ACP synthase III [KO:K00648] [EC:2.3.1.180]
M4V62_11925  ketoacyl-ACP synthase III [KO:K00648] [EC:2.3.1.180]
M4V62_28890  ketoacyl-ACP synthase III [KO:K00648] [EC:2.3.1.180]
M4V62_41935  beta-ketoacyl-ACP synthase II [KO:K09458] [EC:2.3.1.179]
M4V62_28880  fabF; beta-ketoacyl-ACP synthase II [KO:K09458] [EC:2.3.1.179]
M4V62_31915  SDR family oxidoreductase [KO:K00059] [EC:1.1.1.100]
M4V62_35415  fabG; 3-oxoacyl-ACP reductase FabG [KO:K00059] [EC:1.1.1.100]
M4V62_40535  fabG; 3-oxoacyl-ACP reductase FabG [KO:K00059] [EC:1.1.1.100]
M4V62_42335  SDR family oxidoreductase [KO:K00059] [EC:1.1.1.100]
M4V62_02160  SDR family oxidoreductase [KO:K00059] [EC:1.1.1.100]
M4V62_05375  SDR family oxidoreductase [KO:K00059] [EC:1.1.1.100]
M4V62_08220  SDR family oxidoreductase [KO:K00059] [EC:1.1.1.100]
M4V62_09875  SDR family oxidoreductase [KO:K00059] [EC:1.1.1.100]
M4V62_12635  SDR family oxidoreductase [KO:K00059] [EC:1.1.1.100]
M4V62_19280  3-oxoacyl-ACP reductase [KO:K00059] [EC:1.1.1.100]
M4V62_32300  SDR family oxidoreductase [KO:K00059] [EC:1.1.1.100]
M4V62_32440  fabG; 3-oxoacyl-[acyl-carrier-protein] reductase [KO:K00059] [EC:1.1.1.100]
M4V62_00530  fabV; enoyl-[acyl-carrier-protein] reductase FabV [KO:K00209] [EC:1.3.1.9 1.3.1.44]
M4V62_41940  acyl-ACP desaturase [KO:K03921] [EC:1.14.19.2 1.14.19.11 1.14.19.26]
M4V62_07890  acyl-ACP desaturase [KO:K03921] [EC:1.14.19.2 1.14.19.11 1.14.19.26]
M4V62_36045  AMP-binding protein [KO:K01897] [EC:6.2.1.3]
M4V62_37985  acyl-CoA synthetase [KO:K01897] [EC:6.2.1.3]
M4V62_06810  long-chain fatty acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
M4V62_08740  AMP-binding protein [KO:K01897] [EC:6.2.1.3]
M4V62_19180  long-chain fatty acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
M4V62_19270  AMP-dependent synthetase/ligase [KO:K01897] [EC:6.2.1.3]
M4V62_27235  AMP-dependent synthetase/ligase [KO:K01897] [EC:6.2.1.3]
M4V62_27985  AMP-dependent synthetase/ligase [KO:K01897] [EC:6.2.1.3]
M4V62_30425  AMP-binding protein [KO:K01897] [EC:6.2.1.3]
M4V62_33340  AMP-binding protein [KO:K01897] [EC:6.2.1.3]
Compound
C00024  Acetyl-CoA
C00083  Malonyl-CoA
C00154  Palmitoyl-CoA
C00173  Acyl-[acyl-carrier protein]
C00229  Acyl-carrier protein
C00249  Hexadecanoic acid
C00383  Malonate
C00638  Long-chain fatty acid
C00685  3-Oxoacyl-[acyl-carrier protein]
C00693  trans-2,3-Dehydroacyl-[acyl-carrier protein]
C00712  (9Z)-Octadecenoic acid
C01203  Oleoyl-[acyl-carrier protein]
C01209  Malonyl-[acyl-carrier protein]
C01271  (3R)-3-Hydroxyacyl-[acyl-carrier protein]
C01530  Octadecanoic acid
C01571  Decanoic acid
C02679  Dodecanoic acid
C02843  Long-chain acyl-CoA
C03939  Acetyl-[acyl-carrier protein]
C04088  Octadecanoyl-[acyl-carrier protein]
C04180  cis-Dec-3-enoyl-[acp]
C04246  But-2-enoyl-[acyl-carrier protein]
C04618  (3R)-3-Hydroxybutanoyl-[acyl-carrier protein]
C04619  (3R)-3-Hydroxydecanoyl-[acyl-carrier protein]
C04620  (3R)-3-Hydroxyoctanoyl-[acyl-carrier protein]
C04633  (3R)-3-Hydroxypalmitoyl-[acyl-carrier protein]
C04688  (3R)-3-Hydroxytetradecanoyl-[acyl-carrier protein]
C05223  Dodecanoyl-[acyl-carrier protein]
C05744  Acetoacetyl-[acp]
C05745  Butyryl-[acp]
C05746  3-Oxohexanoyl-[acp]
C05747  (3R)-3-Hydroxyhexanoyl-[acyl-carrier protein]
C05748  trans-Hex-2-enoyl-[acp]
C05749  Hexanoyl-[acp]
C05750  3-Oxooctanoyl-[acp]
C05751  trans-Oct-2-enoyl-[acp]
C05752  Octanoyl-[acp]
C05753  3-Oxodecanoyl-[acp]
C05754  trans-Dec-2-enoyl-[acp]
C05755  Decanoyl-[acp]
C05756  3-Oxododecanoyl-[acp]
C05757  (3R)-3-Hydroxydodecanoyl-[acyl-carrier protein]
C05758  trans-Dodec-2-enoyl-[acp]
C05759  3-Oxotetradecanoyl-[acp]
C05760  trans-Tetradec-2-enoyl-[acp]
C05761  Tetradecanoyl-[acp]
C05762  3-Oxohexadecanoyl-[acp]
C05763  trans-Hexadec-2-enoyl-[acp]
C05764  Hexadecanoyl-[acp]
C06423  Octanoic acid
C06424  Tetradecanoic acid
C08362  (9Z)-Hexadecenoic acid
C16219  3-Oxostearoyl-[acp]
C16220  (3R)-3-Hydroxyoctadecanoyl-[acyl-carrier protein]
C16221  (2E)-Octadecenoyl-[acp]
C16520  Hexadecenoyl-[acyl-carrier protein]
C20683  Long-chain acyl-[acyl-carrier protein]
C20794  n-7 Unsaturated acyl-[acyl-carrier protein]
Reference
  Authors
Salas JJ, Ohlrogge JB.
  Title
Characterization of substrate specificity of plant FatA and FatB acyl-ACP thioesterases.
  Journal
Arch Biochem Biophys 403:25-34 (2002)
DOI:10.1016/S0003-9861(02)00017-6
Reference
  Authors
Zhang YM, Marrakchi H, White SW, Rock CO.
  Title
The application of computational methods to explore the diversity and structure of bacterial fatty acid synthase.
  Journal
J Lipid Res 44:1-10 (2003)
DOI:10.1194/jlr.R200016-JLR200
Reference
  Authors
Voelker T, Kinney AJ.
  Title
VARIATIONS IN THE BIOSYNTHESIS OF SEED-STORAGE LIPIDS.
  Journal
Annu Rev Plant Physiol Plant Mol Biol 52:335-361 (2001)
DOI:10.1146/annurev.arplant.52.1.335
Reference
  Authors
Barker GC, Larson TR, Graham IA, Lynn JR, King GJ.
  Title
Novel insights into seed fatty acid synthesis and modification pathways from genetic diversity and quantitative trait Loci analysis of the Brassica C genome.
  Journal
Plant Physiol 144:1827-42 (2007)
DOI:10.1104/pp.107.096172
Reference
  Authors
Bowman CE, Wolfgang MJ
  Title
Role of the malonyl-CoA synthetase ACSF3 in mitochondrial metabolism.
  Journal
Adv Biol Regul 71:34-40 (2019)
DOI:10.1016/j.jbior.2018.09.002
Reference
  Authors
Venkatesan R, Sah-Teli SK, Awoniyi LO, Jiang G, Prus P, Kastaniotis AJ, Hiltunen JK, Wierenga RK, Chen Z
  Title
Insights into mitochondrial fatty acid synthesis from the structure of heterotetrameric 3-ketoacyl-ACP reductase/3R-hydroxyacyl-CoA dehydrogenase.
  Journal
Nat Commun 5:4805 (2014)
DOI:10.1038/ncomms5805
Reference
  Authors
Hiltunen JK, Chen Z, Haapalainen AM, Wierenga RK, Kastaniotis AJ
  Title
Mitochondrial fatty acid synthesis--an adopted set of enzymes making a pathway of major importance for the cellular metabolism.
  Journal
Prog Lipid Res 49:27-45 (2010)
DOI:10.1016/j.plipres.2009.08.001
Reference
  Authors
Kastaniotis AJ, Autio KJ, Keratar JM, Monteuuis G, Makela AM, Nair RR, Pietikainen LP, Shvetsova A, Chen Z, Hiltunen JK
  Title
Mitochondrial fatty acid synthesis, fatty acids and mitochondrial physiology.
  Journal
Biochim Biophys Acta Mol Cell Biol Lipids 1862:39-48 (2017)
DOI:10.1016/j.bbalip.2016.08.011
Related
pathway
sdur00020  Citrate cycle (TCA cycle)
sdur00071  Fatty acid degradation
sdur00410  beta-Alanine metabolism
sdur00561  Glycerolipid metabolism
sdur00564  Glycerophospholipid metabolism
sdur00620  Pyruvate metabolism
sdur00785  Lipoic acid metabolism
KO pathway
ko00061   
LinkDB

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