KEGG PATHWAY: sfe00564

PATHWAY: sfe00564

Entry

sfe00564                    Pathway

Name

Glycerophospholipid metabolism - Shigella flexneri 2002017 (serotype Fxv)

Class

Metabolism; Lipid metabolism

Pathway map

sfe00564

Glycerophospholipid metabolism

Module

sfe_M00093

Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:sfe00564]

Other DBs

GO:

0006650

Organism

Shigella flexneri 2002017 (serotype Fxv) [GN:sfe]

Gene

SFxv_0175

cdsA; Phosphatidate cytidylyltransferase [KO:K00981] [EC:2.7.7.41]

SFxv_0395

pgpA; Phosphatidylglycerophosphatase [KO:K01095] [EC:3.1.3.27]

SFxv_0805

ybhO; putative cardiolipin synthetase ybhO [KO:K06131] [EC:2.7.8.-]

SFxv_1184

ymdC; putative phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases-like enzyme [KO:K06132] [EC:2.7.8.-]

SFxv_1423

cls; Cardiolipin synthetase [KO:K06131] [EC:2.7.8.-]

SFxv_1453

pgpB; Phosphatidylglycerophosphatase B [KO:K01096] [EC:3.1.3.27 3.6.1.75 3.1.3.4 3.6.1.27]

SFxv_2026

ynbB; putative phosphatidate cytidiltransferase [KO:K00981] [EC:2.7.7.41]

SFxv_2184

pgsA; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase [KO:K00995] [EC:2.7.8.5]

SFxv_2562

glpQ; Glycerophosphodiester phosphodiesterase [KO:K01126] [EC:3.1.4.46]

SFxv_2564

glpA; Anaerobic glycerol-3-phosphate dehydrogenase subunit A [KO:K00111] [EC:1.1.5.3]

SFxv_2565

glpB; Anaerobic glycerol-3-phosphate dehydrogenase subunit B [KO:K00112] [EC:1.1.5.3]

SFxv_2566

glpC; Sn-glycerol-3-phosphate dehydrogenase (Anaerobic), K-small subunit [KO:K00113]

SFxv_2756

eutQ; Ethanolamine utilization protein EutA [KO:K04019]

SFxv_2863

yfhB; putative Phosphoserine phosphatase [KO:K18697] [EC:3.1.3.27]

SFxv_2904

pssA; CDP-diacylglycerol--serine O-phosphatidyltransferase [KO:K00998] [EC:2.7.8.8]

SFxv_3121

aas; Bifunctional protein Aas [KO:K05939] [EC:2.3.1.40 6.2.1.20]

SFxv_3361

plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [KO:K00655] [EC:2.3.1.51]

SFxv_3764

glpD; Sn-glycerol-3-phosphate dehydrogenase [KO:K00111] [EC:1.1.5.3]

SFxv_3783

ugpQ; Glycerophosphodiester phosphodiesterase [KO:K01126] [EC:3.1.4.46]

SFxv_3975

gpsA; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase [KO:K00057] [EC:1.1.1.94]

SFxv_4250

pldA; Phospholipase A1 precursor [KO:K01058] [EC:3.1.1.32 3.1.1.4]

SFxv_4254

pldB; Lysophospholipase L [KO:K01048] [EC:3.1.1.5]

SFxv_4357

cdh; CDP-diacylglycerol pyrophosphatase [KO:K01521] [EC:3.6.1.26]

SFxv_4539

dgkA; Diacylglycerol kinase [KO:K00901] [EC:2.7.1.107]

SFxv_4540

plsB; Glycerol-3-phosphate acyltransferase [KO:K00631] [EC:2.3.1.15]

SFxv_4707

psd; Phosphatidylserine decarboxylase proenzyme [KO:K01613] [EC:4.1.1.65]

Compound

C00040

Acyl-CoA

C00065

L-Serine

C00084

Acetaldehyde

C00093

sn-Glycerol 3-phosphate

C00111

Glycerone phosphate

C00114

Choline

C00157

Phosphatidylcholine

C00189

Ethanolamine

C00269

CDP-diacylglycerol

C00307

CDP-choline

C00344

Phosphatidylglycerol

C00346

Ethanolamine phosphate

C00350

Phosphatidylethanolamine

C00416

Phosphatidate

C00513

CDP-glycerol

C00570

CDP-ethanolamine

C00588

Choline phosphate

C00623

sn-Glycerol 1-phosphate

C00641

1,2-Diacyl-sn-glycerol

C00670

sn-Glycero-3-phosphocholine

C00681

1-Acyl-sn-glycerol 3-phosphate

C01194

1-Phosphatidyl-D-myo-inositol

C01210

N-Methylethanolamine phosphate

C01233

sn-Glycero-3-phosphoethanolamine

C01241

Phosphatidyl-N-methylethanolamine

C01996

Acetylcholine

C02737

Phosphatidylserine

C03372

Acylglycerone phosphate

C03819

1-Acylglycerophosphoinositol

C03872

L-Serine-phosphoethanolamine

C03892

Phosphatidylglycerophosphate

C03974

2-Acyl-sn-glycerol 3-phosphate

C04230

1-Acyl-sn-glycero-3-phosphocholine

C04233

2-Acyl-sn-glycero-3-phosphocholine

C04308

Phosphatidyl-N-dimethylethanolamine

C04438

1-Acyl-sn-glycero-3-phosphoethanolamine

C04590

3-(O-Geranylgeranyl)-sn-glycerol 1-phosphate

C04638

2,3-Bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate

C05973

2-Acyl-sn-glycero-3-phosphoethanolamine

C05974

2-Acyl-sn-glycero-3-phosphoserine

C05976

Aminoacyl-phosphatidylglycerol

C05980

Cardiolipin

C06771

Triethanolamine

C06772

Diethanolamine

C13482

Phosphodimethylethanolamine

C18059

CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol

C18125

1-Acyl-sn-glycero-3-phosphoserine

C18126

1-Acyl-sn-glycero-3-phosphoglycerol

C18129

Monolysocardiolipin

C18168

Diacylglycerylhomoserine

C18169

Diacylglyceryl-N,N,N-trimethylhomoserine

C20466

2,3-Bis-(O-geranylgeranyl)-sn-glycero-1-phospho-L-serine

C20518

2,3-Bis-(O-phytanyl)-sn-glycerol 1-phosphate

C22340

Heptaprenylglyceryl phosphate

C22341

Heptaprenylglycerol

C22342

Diacetylheptaprenylglycerol

Reference

PMID:1512203

Authors

Racenis PV, Lai JL, Das AK, Mullick PC, Hajra AK, Greenberg ML.

Title

The acyl dihydroxyacetone phosphate pathway enzymes for glycerolipid biosynthesis are present in the yeast Saccharomyces cerevisiae.

Journal

J Bacteriol 174:5702-10 (1992)
DOI:10.1128/JB.174.17.5702-5710.1992

Reference

PMID:10092508

Authors

Taniyama Y, Shibata S, Kita S, Horikoshi K, Fuse H, Shirafuji H, Sumino Y, Fujino M.

Title

Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase.

Journal

Biochem Biophys Res Commun 257:50-6 (1999)
DOI:10.1006/bbrc.1999.0411

Reference

PMID:10542045

Authors

Athenstaedt K, Daum G.

Title

Phosphatidic acid, a key intermediate in lipid metabolism.

Journal

Eur J Biochem 266:1-16 (1999)
DOI:10.1046/j.1432-1327.1999.00822.x

Reference

PMID:12431977

Authors

Shields DJ, Lehner R, Agellon LB, Vance DE.

Title

Membrane topography of human phosphatidylethanolamine N-methyltransferase.

Journal

J Biol Chem 278:2956-62 (2003)
DOI:10.1074/jbc.M210904200

Reference

PMID:14663079

Authors

Martinez-Morales F, Schobert M, Lopez-Lara IM, Geiger O.

Title

Pathways for phosphatidylcholine biosynthesis in bacteria.

Journal

Microbiology 149:3461-71 (2003)
DOI:10.1099/mic.0.26522-0

Reference

PMID:15522832

Authors

Burgermeister M, Birner-Grunberger R, Nebauer R, Daum G.

Title

Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae.

Journal

Biochim Biophys Acta 1686:161-8 (2004)
DOI:10.1016/j.bbalip.2004.09.007

Reference

PMID:1649829

Authors

Hsu L, Jackowski S, Rock CO

Title

Isolation and characterization of Escherichia coli K-12 mutants lacking both 2-acyl-glycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synthetase activity.

Journal

J Biol Chem 266:13783-8 (1991)

Reference

PMID:10938271

Authors

Stone SJ, Vance JE.

Title

Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes.

Journal

J Biol Chem 275:34534-40 (2000)
DOI:10.1074/jbc.M002865200

Related
pathway

sfe00010