Entry
Name
ABC transporters - Serratia inhibens
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
BRITE hierarchy
Pathway map
Other DBs
Organism
Serratia inhibens [GN:
sply ]
Gene
Q5A_001010 livH_1; High-affinity branched-chain amino acid transport system permease protein LivH [KO:K01997 ]
Q5A_001020 lptB_1; Lipopolysaccharide export system ATP-binding protein LptB [KO:K01995 ]
Q5A_001025 livF_1; High-affinity branched-chain amino acid transport ATP-binding protein LivF [KO:K01996 ]
Q5A_001035 ugpB; sn-glycerol-3-phosphate-binding periplasmic protein UgpB [KO:K05813 ]
Q5A_001040 ugpA; sn-glycerol-3-phosphate transport system permease protein UgpA [KO:K05814 ]
Q5A_002365 lptF; Lipopolysaccharide export system permease protein LptF [KO:K07091 ]
Q5A_002370 lptG; Lipopolysaccharide export system permease protein LptG [KO:K11720 ]
Q5A_005030 yheI; putative multidrug resistance ABC transporter ATP-binding/permease protein YheI [KO:K18889 ]
Q5A_005035 mdlB_1; Multidrug resistance-like ATP-binding protein MdlB [KO:K18890 ]
Q5A_006050 gltK_1; Glutamate/aspartate transport system permease protein GltK [KO:K10002 ]
Q5A_006055 glnM_2; putative glutamine ABC transporter permease protein GlnM [KO:K10003 ]
Q5A_006615 livF_2; High-affinity branched-chain amino acid transport ATP-binding protein LivF [KO:K11963 ]
Q5A_006880 argT_1; Lysine/arginine/ornithine-binding periplasmic protein [KO:K10013 ]
Q5A_007130 livH_2; High-affinity branched-chain amino acid transport system permease protein LivH [KO:K11960 ]
Q5A_007140 lptB_2; Lipopolysaccharide export system ATP-binding protein LptB [KO:K11962 ]
Q5A_007145 livF_3; High-affinity branched-chain amino acid transport ATP-binding protein LivF [KO:K11963 ]
Q5A_007245 osmF; Putative osmoprotectant uptake system substrate-binding protein OsmF [KO:K05845 ]
Q5A_007250 yehY_1; Putative osmoprotectant uptake system permease protein YehY [KO:K05846 ]
Q5A_007260 yehW; Putative osmoprotectant uptake system permease protein YehW [KO:K05846 ]
Q5A_007700 gsiC_1; Glutathione transport system permease protein GsiC [KO:K13890 ]
Q5A_007705 gsiD_1; Glutathione transport system permease protein GsiD [KO:K13891 ]
Q5A_008205 ydcV; Inner membrane ABC transporter permease protein YdcV [KO:K11074 ]
Q5A_008245 artI; Putative ABC transporter arginine-binding protein 2 [KO:K09997 ]
Q5A_008325 macB_1; Macrolide export ATP-binding/permease protein MacB [KO:K05685 ] [EC:7.6.2.-]
Q5A_008625 ssuC_1; Putative aliphatic sulfonates transport permease protein SsuC [KO:K15554 ]
Q5A_009210 macB_2; Macrolide export ATP-binding/permease protein MacB [KO:K05685 ] [EC:7.6.2.-]
Q5A_009870 mglA_2; Galactose/methyl galactoside import ATP-binding protein MglA [KO:K17215 ]
Q5A_010040 lolC; Lipoprotein-releasing system transmembrane protein LolC [KO:K09808 ]
Q5A_010045 lolD_2; Lipoprotein-releasing system ATP-binding protein LolD [KO:K09810 ] [EC:7.6.2.-]
Q5A_010050 lolE; Lipoprotein-releasing system transmembrane protein LolE [KO:K09808 ]
Q5A_010770 ecfA3; Energy-coupling factor transporter ATP-binding protein EcfA3 [KO:K11607 ]
Q5A_011765 ugpC_2; sn-glycerol-3-phosphate import ATP-binding protein UgpC [KO:K10112 ] [EC:7.5.2.-]
Q5A_012340 malK_1; Maltose/maltodextrin import ATP-binding protein MalK [KO:K10111 ] [EC:7.5.2.-]
Q5A_012480 argT_2; Lysine/arginine/ornithine-binding periplasmic protein [KO:K10014 ]
Q5A_013160 malK_2; Maltose/maltodextrin import ATP-binding protein MalK [KO:K10111 ] [EC:7.5.2.-]
Q5A_013335 phnV_1; Putative 2-aminoethylphosphonate transport system permease protein PhnV [KO:K02011 ]
Q5A_013405 livH_3; High-affinity branched-chain amino acid transport system permease protein LivH [KO:K01997 ]
Q5A_013410 livH_4; High-affinity branched-chain amino acid transport system permease protein LivH [KO:K01998 ]
Q5A_013415 lptB_3; Lipopolysaccharide export system ATP-binding protein LptB [KO:K01995 ]
Q5A_013420 livF_4; High-affinity branched-chain amino acid transport ATP-binding protein LivF [KO:K01996 ]
Q5A_013425 braC; Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein [KO:K01999 ]
Q5A_013765 ddpD_2; putative D,D-dipeptide transport ATP-binding protein DdpD [KO:K19229 ]
Q5A_014065 oppC; Oligopeptide transport system permease protein OppC [KO:K15582 ]
Q5A_014070 oppB; Oligopeptide transport system permease protein OppB [KO:K15581 ]
Q5A_014495 znuB; High-affinity zinc uptake system membrane protein ZnuB [KO:K09816 ]
Q5A_015240 yecS_3; Inner membrane amino-acid ABC transporter permease protein YecS [KO:K10009 ]
Q5A_016285 ycjO; Inner membrane ABC transporter permease protein YcjO [KO:K02011 ]
Q5A_016325 ssuB_3; Aliphatic sulfonates import ATP-binding protein SsuB [KO:K15600 ]
Q5A_016330 ssuC_4; Putative aliphatic sulfonates transport permease protein SsuC [KO:K15599 ]
Q5A_016765 livF_5; High-affinity branched-chain amino acid transport ATP-binding protein LivF [KO:K01996 ]
Q5A_016770 lptB_4; Lipopolysaccharide export system ATP-binding protein LptB [KO:K01995 ]
Q5A_016775 livH_5; High-affinity branched-chain amino acid transport system permease protein LivH [KO:K01998 ]
Q5A_016780 livH_6; High-affinity branched-chain amino acid transport system permease protein LivH [KO:K01997 ]
Q5A_016845 yehY_2; Putative osmoprotectant uptake system permease protein YehY [KO:K05846 ]
Q5A_016945 argT_3; Lysine/arginine/ornithine-binding periplasmic protein [KO:K10014 ]
Q5A_017155 yejB; Inner membrane ABC transporter permease protein YejB [KO:K13894 ]
Q5A_017160 yejE; Inner membrane ABC transporter permease protein YejE [KO:K13895 ]
Q5A_018125 fepD; Ferric enterobactin transport system permease protein FepD [KO:K23186 ]
Q5A_018130 fepG; Ferric enterobactin transport system permease protein FepG [KO:K23187 ]
Q5A_018135 yusV; putative siderophore transport system ATP-binding protein YusV [KO:K23188 ]
Q5A_018265 macB_3; Macrolide export ATP-binding/permease protein MacB [KO:K05685 ] [EC:7.6.2.-]
Q5A_018760 pstC2; Phosphate transport system permease protein PstC 2 [KO:K02037 ]
Q5A_019720 proW; Glycine betaine/L-proline transport system permease protein ProW [KO:K02001 ]
Q5A_019845 metI; D-methionine transport system permease protein MetI [KO:K02072 ]
Q5A_020370 macB_4; Macrolide export ATP-binding/permease protein MacB [KO:K05685 ] [EC:7.6.2.-]
Q5A_021070 fhuB; Iron(3+)-hydroxamate import system permease protein FhuB [KO:K23228 ]
Q5A_022700 mlaB; putative phospholipid ABC transporter-binding protein MlaB [KO:K07122 ]
Q5A_022710 mlaD; putative phospholipid ABC transporter-binding protein MlaD [KO:K02067 ]
Q5A_022715 mlaE; putative phospholipid ABC transporter permease protein MlaE [KO:K02066 ]
Q5A_022720 mlaF; putative phospholipid import ATP-binding protein MlaF [KO:K02065 ]
Q5A_023300 malK_3; Maltose/maltodextrin import ATP-binding protein MalK [KO:K10111 ] [EC:7.5.2.-]
Q5A_023765 ssuC_5; Putative aliphatic sulfonates transport permease protein SsuC [KO:K15552 ]
Q5A_024710 yjfF; Inner membrane ABC transporter permease protein YjfF [KO:K23509 ]
Q5A_024715 ytfT; Inner membrane ABC transporter permease protein YtfT [KO:K23509 ]
Compound
C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference
Authors
Tomii K, Kanehisa M.
Title
A comparative analysis of ABC transporters in complete microbial genomes.
Journal
Reference
Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal
Reference
Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal
Reference
Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal
Reference
Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal
Reference
Authors
Richard-Fogal CL, Frawley ER, Kranz RG
Title
Topology and function of CcmD in cytochrome c maturation.
Journal
Reference
Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal
Reference
Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal
Reference
Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal
Reference
Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal
KO pathway