Entry
Name
ABC transporters - Streptomyces reticuli
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
BRITE hierarchy
Pathway map
Other DBs
Organism
Streptomyces reticuli [GN:
srw ]
Gene
TUE45_00147 ugpB; sn-glycerol-3-phosphate-binding periplasmic protein UgpB precursor [KO:K17244 ]
TUE45_00256 opuCC; Glycine betaine/carnitine/choline-binding protein OpuCC precursor [KO:K05845 ]
TUE45_01492 ssuC; Putative aliphatic sulfonates transport permease protein SsuC [KO:K15554 ]
TUE45_01494 ssuA_1; Putative aliphatic sulfonates-binding protein precursor [KO:K15553 ]
TUE45_02256 yusV_2; putative siderophore transport system ATP-binding protein YusV [KO:K23188 ]
TUE45_02257 fepG; Ferric enterobactin transport system permease protein FepG [KO:K23187 ]
TUE45_02258 yfiZ_1; putative siderophore transport system permease protein YfiZ precursor [KO:K23186 ]
TUE45_02521 livH; High-affinity branched-chain amino acid transport system permease protein LivH [KO:K01997 ]
TUE45_02524 livF; High-affinity branched-chain amino acid transport ATP-binding protein LivF [KO:K01996 ]
TUE45_02818 drrA_5; Daunorubicin/doxorubicin resistance ATP-binding protein DrrA [KO:K18232 ]
TUE45_02819 drrB_2; Daunorubicin/doxorubicin resistance ABC transporter permease protein DrrB [KO:K18233 ]
TUE45_02919 ecfT_1; Energy-coupling factor transporter transmembrane protein EcfT [KO:K16785 ]
TUE45_02992 sbpA; Multiple sugar-binding periplasmic protein SbpA precursor [KO:K10546 ]
TUE45_03103 znuA; High-affinity zinc uptake system binding-protein ZnuA precursor [KO:K09815 ]
TUE45_03243 ugpC_1; sn-glycerol-3-phosphate import ATP-binding protein UgpC [KO:K10112 ] [EC:7.5.2.-]
TUE45_03245 ugpC_2; sn-glycerol-3-phosphate import ATP-binding protein UgpC [KO:K10112 ] [EC:7.5.2.-]
TUE45_03669 yfiZ_2; putative siderophore transport system permease protein YfiZ precursor [KO:K23186 ]
TUE45_03670 yfhA; putative siderophore transport system permease protein YfhA [KO:K23187 ]
TUE45_03671 yusV_3; putative siderophore transport system ATP-binding protein YusV [KO:K23188 ]
TUE45_03672 yfiY; putative siderophore-binding lipoprotein YfiY precursor [KO:K25286 ]
TUE45_04496 ecfA3; Energy-coupling factor transporter ATP-binding protein EcfA3 [KO:K02006 ]
TUE45_04497 ecfT_2; Energy-coupling factor transporter transmembrane protein EcfT [KO:K02008 ]
TUE45_05349 opuAB_2; Glycine betaine transport system permease protein OpuAB [KO:K02001 ]
TUE45_05350 gbuC; Glycine betaine/carnitine transport binding protein GbuC precursor [KO:K02002 ]
TUE45_05429 mglA_2; Galactose/methyl galactoside import ATP-binding protein MglA [KO:K23537 ]
TUE45_06271 glnP; putative glutamine ABC transporter permease protein GlnP [KO:K10007 ]
TUE45_06272 glnM_3; putative glutamine ABC transporter permease protein GlnM [KO:K10006 ]
TUE45_06273 glnH_5; ABC transporter glutamine-binding protein GlnH precursor [KO:K10005 ]
TUE45_06406 drrA_13; Daunorubicin/doxorubicin resistance ATP-binding protein DrrA [KO:K18232 ]
TUE45_06407 drrB_4; Daunorubicin/doxorubicin resistance ABC transporter permease protein DrrB [KO:K18233 ]
TUE45_06675 opuCD; Glycine betaine/carnitine/choline transport system permease protein OpuCD [KO:K05846 ]
TUE45_06681 osmF; Putative osmoprotectant uptake system substrate-binding protein OsmF precursor [KO:K05845 ]
TUE45_06735 ssuA_2; Putative aliphatic sulfonates-binding protein precursor [KO:K15553 ]
TUE45_07014 glnH_6; ABC transporter glutamine-binding protein GlnH precursor [KO:K10005 ]
TUE45_07015 glnM_4; putative glutamine ABC transporter permease protein GlnM [KO:K10006 ]
TUE45_07016 yecS_3; Inner membrane amino-acid ABC transporter permease protein YecS [KO:K10007 ]
TUE45_pSRc_0496 livH; High-affinity branched-chain amino acid transport system permease protein LivH [KO:K01997 ]
TUE45_pSRc_0498 livF; High-affinity branched-chain amino acid transport ATP-binding protein LivF [KO:K01996 ]
Compound
C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference
Authors
Tomii K, Kanehisa M.
Title
A comparative analysis of ABC transporters in complete microbial genomes.
Journal
Reference
Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal
Reference
Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal
Reference
Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal
Reference
Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal
Reference
Authors
Richard-Fogal CL, Frawley ER, Kranz RG
Title
Topology and function of CcmD in cytochrome c maturation.
Journal
Reference
Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal
Reference
Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal
Reference
Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal
Reference
Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal
KO pathway