KEGG   PATHWAY: vij00290
Entry
vij00290                    Pathway                                
Name
Valine, leucine and isoleucine biosynthesis - Viridibacillus arvi
Class
Metabolism; Amino acid metabolism
Pathway map
vij00290  Valine, leucine and isoleucine biosynthesis
vij00290

Module
vij_M00019  Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:vij00290]
vij_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:vij00290]
vij_M00570  Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:vij00290]
Other DBs
GO: 0009097 0009098 0009099
Organism
Viridibacillus arvi [GN:vij]
Gene
JNUCC6_03725  leuD; 3-isopropylmalate dehydratase small subunit [KO:K01704] [EC:4.2.1.33 4.2.1.35]
JNUCC6_03730  leuC; 3-isopropylmalate dehydratase large subunit [KO:K01703] [EC:4.2.1.33 4.2.1.35]
JNUCC6_03735  leuB; 3-isopropylmalate dehydrogenase [KO:K00052] [EC:1.1.1.85]
JNUCC6_03740  [KO:K01649] [EC:2.3.3.13]
JNUCC6_03745  ilvC; ketol-acid reductoisomerase [KO:K00053] [EC:1.1.1.86]
JNUCC6_03750  ilvN; acetolactate synthase small subunit [KO:K01653] [EC:2.2.1.6]
JNUCC6_03755  ilvB; acetolactate synthase large subunit [KO:K01652] [EC:2.2.1.6]
JNUCC6_03760  ilvD; dihydroxy-acid dehydratase [KO:K01687] [EC:4.2.1.9]
JNUCC6_03765  ilvE; branched-chain-amino-acid transaminase [KO:K00826] [EC:2.6.1.42]
JNUCC6_07325  [KO:K00263] [EC:1.4.1.9]
JNUCC6_17240  ilvA; threonine ammonia-lyase IlvA [KO:K01754] [EC:4.3.1.19]
JNUCC6_18805  [KO:K01649] [EC:2.3.3.13]
Compound
C00022  Pyruvate
C00024  Acetyl-CoA
C00109  2-Oxobutanoate
C00123  L-Leucine
C00141  3-Methyl-2-oxobutanoic acid
C00183  L-Valine
C00188  L-Threonine
C00233  4-Methyl-2-oxopentanoate
C00407  L-Isoleucine
C00671  (S)-3-Methyl-2-oxopentanoic acid
C02226  2-Methylmaleate
C02504  alpha-Isopropylmalate
C02612  (R)-2-Methylmalate
C02631  2-Isopropylmaleate
C04181  3-Hydroxy-3-methyl-2-oxobutanoic acid
C04236  (2S)-2-Isopropyl-3-oxosuccinate
C04272  (R)-2,3-Dihydroxy-3-methylbutanoate
C04411  (2R,3S)-3-Isopropylmalate
C06006  (S)-2-Aceto-2-hydroxybutanoate
C06007  (R)-2,3-Dihydroxy-3-methylpentanoate
C06010  (S)-2-Acetolactate
C06032  D-erythro-3-Methylmalate
C14463  (R)-3-Hydroxy-3-methyl-2-oxopentanoate
Reference
  Authors
Xu H, Zhang Y, Guo X, Ren S, Staempfli AA, Chiao J, Jiang W, Zhao G.
  Title
Isoleucine biosynthesis in Leptospira interrogans serotype lai strain 56601 proceeds via a threonine-independent pathway.
  Journal
J Bacteriol 186:5400-9 (2004)
DOI:10.1128/JB.186.16.5400-5409.2004
Related
pathway
vij00260  Glycine, serine and threonine metabolism
vij00280  Valine, leucine and isoleucine degradation
vij00620  Pyruvate metabolism
KO pathway
ko00290   

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