Messenger RNA Biogenesis - Heterocephalus glaber (naked mole-rat)

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     KO
 Eukaryotic type
   mRNA processing factors
   mRNA surveillance and transport factors
   mRNA degradation factors
     5'-3' decay
     3'-5' decay
       Core exosome factors
       Exosome cofactors
       TRAMP complex
       Ski complex
       Ccr4-NOT complex
       Pan complex
       Other 3'-5' decay factors
         101715275 Parn; poly(A)-specific ribonuclease
         101709845 Pnldc1; PARN like, ribonuclease domain containing 1
         101714069 Dhx36; DEAH-box helicase 36
         101716692 Btg3; BTG anti-proliferation factor 3
         101712701 protein BTG4-like
         101724408 Btg1; BTG anti-proliferation factor 1
         101699455 protein Tob1-like
         101717914 Btg4; BTG anti-proliferation factor 4
         101702273 Btg2; BTG anti-proliferation factor 2
         101720365 Tob1; transducer of ERBB2, 1
         101704991 protein BTG3-like
         101724943 Csf2; colony stimulating factor 2
         101710110 Noct; nocturnin
         101703353 Eri1; exoribonuclease 1
         101703293 Eri2; ERI1 exoribonuclease family member 2
         101715664 Dcps; decapping enzyme, scavenger
         101710298 Pde12; phosphodiesterase 12
         101703036 Ireb2; iron responsive element binding protein 2
         101699823 Helz; helicase with zinc finger
         101722730 Helz2; helicase with zinc finger 2
         101714673 Nrde2; NRDE-2, necessary for RNA interference, domain containing
         101707256 Samd4a; sterile alpha motif domain containing 4A
         101699881 Samd4b; sterile alpha motif domain containing 4B
         101698157 Focad; focadhesin
K01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4] 
K01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4] 
K14442 DHX36; ATP-dependent RNA helicase DHX36 [EC:5.6.2.6] 
K14443 TOB; protein Tob/BTG 
K14443 TOB; protein Tob/BTG 
K14443 TOB; protein Tob/BTG 
K14443 TOB; protein Tob/BTG 
K14443 TOB; protein Tob/BTG 
K14443 TOB; protein Tob/BTG 
K14443 TOB; protein Tob/BTG 
K14443 TOB; protein Tob/BTG 
K05427 CSF2; granulocyte-macrophage colony-stimulating factor 
K18764 NOCT; nocturnin [EC:3.1.3.108] 
K18416 THEX1; 3'-5' exoribonuclease 1 [EC:3.1.-.-] 
K18417 ERI2; ERI1 exoribonuclease 2 [EC:3.1.-.-] 
K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59] 
K19612 PDE12; 2',5'-phosphodiesterase [EC:3.1.13.4 3.1.4.-] 
K22416 IREB2; iron-responsive element-binding protein 2 
K25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-] 
K25165 HELZ2; 3'-5' exoribonuclease HELZ2 [EC:3.1.13.1 5.6.2.6] 
K26109 NRDE2; nuclear exosome regulator NRDE2 
K27396 SMG; protein Smaug 
K27396 SMG; protein Smaug 
K27498 FOCAD; focadhesin 
     Other degradation factors
 
 Prokaryotic type

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Last updated: April 25, 2024