Eukaryotic type
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SSBR (single strand breaks repair)
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DSBR (double strand breaks repair)
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HR (homologous recombination)
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MRN(MRX) complex
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BRCA1-core complex
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BRCA1-A complex
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BRCA1-B complex
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BRCA1-C complex
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BRCA complex
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RecA family proteins
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Rad52 family proteins
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Rad54 family proteins
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RecQ family DNA helicases
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Bloom's syndrome complex (BTR)
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RPA (replication factor A)
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Protein phosphatase 4
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AP-5 complex
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SMC5-SMC6 complex
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Other HR factors
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K10882 EME1, MMS4; crossover junction endonuclease EME1 [EC:3.1.22.-]
K10883 EME2; crossover junction endonuclease EME2
K20777 EXD2; exonuclease 3'-5' domain-containing protein 2 [EC:3.1.11.1]
K08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-]
K10881 SHFM1, DSS1, RPN15; 26 proteasome complex subunit DSS1
K10991 SWI5, SAE3; DNA repair protein Swi5/Sae3
K10992 SFR1; Swi5-dependent recombination DNA repair protein 1
K15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]
K10484 BTBD12, SLX4; structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)
K15079 SLX4; structure-specific endonuclease subunit SLX4
K15338 GEN1, YEN1; holliday junction resolvase GEN1/YEN1 [EC:3.1.-.-]
K19026 SPG11; spatacsin
K19027 ZFYVE26; zinc finger FYVE domain-containing protein 26
K20778 RAD51AP1; RAD51-associated protein 1
K28888 NUCKS1; nuclear ubiquitous casein and cyclin-dependent kinase substrate 1
K11339 MORF4L1, MRG15, EAF3; mortality factor 4-like protein 1
K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
K22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]
K22806 SPIDR; DNA repair-scaffolding protein
K22810 FAM84B; protein FAM84B
K23112 BRAT1; BRCA1-associated ATM activator 1
K23456 CFAP410, C21ORF2; cilla- and flagella-associated protein
K25065 HDGFL2; hepatoma-derived growth factor-related protein 2
K25770 ZSWIM7, SWS1; zinc finger SWIM domain-containing protein 7
K25771 SWSAP1; ATPase SWSAP1
K25790 EMSY; BRCA2-interacting transcriptional repressor EMSY
K25791 HSF2BP; heat shock factor 2-binding protein
K26125 MMS22L; protein MMS22-like
K09257 NFKBIL2; NF-kappa-B inhibitor-like protein 2
K27262 BOD1L1; biorientation of chromosomes in cell division protein 1-like 1
K27412 PARPBP; PCNA-interacting partner
K27803 HROB; homologous recombination OB-fold protein
K10737 MCM8; DNA helicase MCM8 [EC:5.6.2.4]
K10738 MCM9; DNA helicase MCM9 [EC:5.6.2.4]
K15047 HNRNPUL1, E1BAP5; heterogeneous nuclear ribonucleoprotein U-like protein 1
K28611 HNRNPUL2; heterogeneous nuclear ribonucleoprotein U-like protein 2
K28623 MRNIP; MRN complex-interacting protein
K29002 RADX; RPA-related protein RADX
K29038 RBM6; RNA-binding protein 6
K22807 WRNexo; werner syndrome-like exonuclease [EC:3.1.11.-]
K22685 WSS1; DNA-dependent metalloprotease WSS1 [EC:3.4.24.-]
K26559 WHY1; single-stranded DNA-binding protein WHY1
K26561 WHY2; single-stranded DNA-binding protein WHY2
K26560 WHY3; single-stranded DNA-binding protein WHY3
K14635 MPH1; ATP-dependent DNA helicase MPH1 [EC:5.6.2.4]
K15080 SAW1; single-strand annealing weakened protein 1
K26124 RTT101, CUL8; cullin 8
K26122 MMS22; E3 ubiquitin-protein ligase substrate receptor MMS22
K26123 MMS1; E3 ubiquitin-protein ligase linker protein MMS1
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NHEJ (non-homologous end-joining)
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FA (Fanconi anemia) pathway
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Other DSBR factors
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TLS (translesion DNA synthesis) factors
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Y-family DNA polymerases
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B-family DNA polymerases
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A-family DNA polymerase
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Rad6 epistasis group
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K10573 UBE2A, UBC2, RAD6A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
K10574 UBE2B, RAD6B; ubiquitin-conjugating enzyme E2 B [EC:2.3.2.23]
K10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]
K15505 RAD5; DNA repair protein RAD5 [EC:5.6.2.-]
K15711 SMARCA3, HLTF; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]
K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
K10580 UBE2N, BLU, UBC13; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
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Other TLS factors
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Check point factors
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Other factors with a suspected DNA repair function
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Prokaryotic type
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SSBR (single strand breaks repair)
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DSBR (double strand breaks repair)
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HR (homologous recombination)
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RecBC pathway proteins
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RecFOR pathway proteins
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AddAB pathway proteins
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Other HR factor
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Archaeal homologous recombinant proteins
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K04483 radA; DNA repair protein RadA
K04484 radB; DNA repair protein RadB
K03552 hjr, hjc, hje; holliday junction resolvase [EC:3.1.21.10]
K03546 sbcC, rad50; DNA repair protein SbcC/Rad50
K03547 sbcD, mre11; DNA repair protein SbcD/Mre11
K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
K25510 nurA; DNA double-strand break repair nuclease NurA [EC:3.1.-.-]
K03726 helS; ATP-dependent DNA helicase [EC:5.6.2.4]
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NHEJ (non-homologous end-joining)
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TLS (translesion DNA synthesis) factors
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Other factors with a suspected DNA repair function
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