KEGG
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Auto annotation
Kanehisa Lab
KEGG in Keg

KEGG Syntax - User data analysis

Syntax Genome alignment Genome similarity Taxonomy mapping User data analysis

KO composition analysis

Given a set of KOs (K numbers), this interface searches similar KEGG organisms or KEGG organism groups (see Genome similarity for details) with different similarity measures.

Enter a set of K numbers

Or upload file:
Select operation
Find similar KEGG organisms by KOs
Find similar KEGG organism groups by KOs
Find similar KEGG organisms by modules
Report complete modules (used above)
Threshold similarity: %

KO sequence analysis

When KOs are associated with the ordered gene set in the genome, conserved synteny may be identified by the KO sequence (gene order) alignment with a KEGG organism (see Genome alignment for details).

Enter query data with assigned K numbers

Or upload file:

Select genome to be compared
Genome ID:   




Query data example:
   eco_ko.txt

Genome ID examples
   bsu   2510464

Notes
  1. The query dataset is an ordered list of genes along the chromosome that are annotated with K numbers. It must be prepared as a tab-delimited two-column dataset with the user's gene identifiers in the first column and assigned K numbers in the second column. This is consistent with the output files of automatic annotation servers: BlastKOALA and GhostKOALA.
  2. Genome ID may be KEGG organism code or vtax number (virus taxonomy ID). Use the "Find similar KEGG organisms" button to obtain cadidates of genomes to be compared according to the KO composiition similarity.

Last updated: April 1, 2026