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Entry Name Description Category Pathway
H01646 Major depressive disorder Major depressive disorder (MDD) is the most common psychiatric disorder mainly characterized by depressed mood, loss of interest, feelings of worthlessness, and a high risk of suicide. Accumulated evidence ... Mental and behavioural disorder
H01647 Subacute thyroiditis
Subacute granulomatous thyroiditis
De Quervain thyroiditis
Subacute thyroiditis (SAT), also called subacute granulomatous or de Quervain thyroiditis, is a spontaneously remitting, painful, inflammatory disease of the thyroid gland, which is considered the most ... Endocrine and metabolic disease
H01648 Pemphigus Pemphigus is an autoimmune blistering disease of the skin and mucous membranes characterized by circulating autoantibodies that target desmosomal components as well as other epithelial antigens and impair ... Immune system disease; Skin disease
H01649 Schizophrenia Schizophrenia (SCZD) is a common serious psychotic illness that typically emerges in late adolescence and early adulthood. It is characterized by hallucinations and delusions (commonly known as positive ... Mental and behavioural disorder
H01650 Pemphigoid Pemphigoid diseases are group of autoimmune blistering disorders of the skin and mucous membranes characterized by autoantibodies directed against structural proteins of the dermal-epidermal junction that ... Immune system disease; Skin disease
H01651 Macular edema Macular edema is a common feature of many diseases of the retina, such as intraocular inflammation (uveitis), central or branch retinal vein occlusion, diabetic retinopathy and following cataract extraction ... Nervous system disease
H01652 Seborrheic dermatitis Seborrheic dermatitis (SD) is a common inflammatory dermatological disorder. The characteristic symptoms include scaling, erythema, and itching, which occur most often on the scalp, face, chest, back, ... Immune system disease; Skin disease
H01653 Bipolar disorder
Manic depressive illness
Bipolar disorder, previously known as manic depressive illness, is a severe chronic mood disorder, characterized by the recurrence of mania (hypomania), depression, or mixed episodes. It is one of the ... Mental and behavioural disorder
H01654 Lichen planus Lichen planus (LP) is a chronic inflammatory and immune mediated skin disease with characteristic clinical and histopathologic features. The skin and oral mucosa are the most frequently involved areas ... Immune system disease; Skin disease
H01655 Granulomatosis with polyangiitis
Wegener granulomatosis
Granulomatosis with polyangitis (GPA) is an idiopathic, systemic inflammatory disease characterized by necrotizing granulomatous inflammation and pauci-immune small- vessel vasculitis of upper and lower ... Immune system disease
H01656 Psoriasis Psoriasis (PSORS) is a chronic, immune-mediated inflammatory skin disease, characterized by increased propagation of the epidermis with dilation of dermal capillaries. The major symptoms of psoriasis are ... Immune system disease; Skin disease
H01657 Nephrotic syndrome Nephrotic syndrome (NPHS) is a heterogeneous group of disorders characterized by heavy proteinuria (more than 3.5 grams per day), hypoalbuminemia, hyperlipidemia, and edema. Congenital nephrotic syndrome ... Urinary system disease
H01658 Microscopic polyangiitis Microscopic polyangiitis (MPA) is an idiopathic autoimmune disease characterized by systemic vasculitis. MPA predominantly affects small-calibre blood vessels and is associated with the presence of antineutrophil ... Immune system disease
H01659 Pityriasis rubra pilaris Pityriasis rubra pilaris (PRP) is a spectrum of rare chronic inflammatory disorders with papulosquamous eruptions of unknown cause. The prototypical clinical characteristics of PRP are follicular hyperkeratotic ... Immune system disease; Skin disease
H01660 Pityriasis rosea Pityriasis rosea (PR) is an acute exanthem, which prevalently affects children and young adults. The cause of PR is uncertain but epidemiological (seasonal variation and clustering in communities) and ... Skin disease
H01661 Xanthoma
Xanthomatosis
Xanthomas are benign and usually yellow plaques, papules, or nodules that develop in the cutis and subcutaneous tissue. They evolve as clusters of foam cells and favor the neck, upper trunk, flexural folds ... Skin disease; Inherited metabolic disorder
H01662 Generalized anxiety disorder
Anxiety neurosis
Generalized anxiety disorder is a persistent and common mental disorder. This disorder is twice as common in women than it is in men. The symptoms include generalised and persistent excessive anxiety and ... Mental and behavioural disorder
H01663 Pustular psoriasis Pustular psoriasis is a form of psoriasis [DS:H01656] characterized by multiple tender sterile pustules with an underlying, blotchy, erythematous base. It has been classified into localized and generalized ... Immune system disease; Skin disease
H01664 Panic disorder Panic disorder (PD) is a common type of anxiety disorder, characterized by unexpected and repeated panic attacks or fear of future panic attacks. It has a rapid onset and includes symptoms such as palpitations ... Mental and behavioural disorder
H01665 Primary peritoneal carcinoma Female primary peritoneal carcinoma (PPC) has the characteristic of diffuse involvement of the peritoneum by papillary carcinoma in the absence of an obvious primary site and grossly normal ovaries, or ... Cancer
H01666 Angiosarcoma Angiosarcomas are rare, generally aggressive, malignant mesenchymal tumours of vascular origin and constitute less than 1% of all sarcomas. Their most frequent site of origin is the head and neck, especially ... Cancer
H01667 Medulloblastoma Medulloblastoma is the most common embryonal CNS tumor of childhood and is likely composed of biologically different subsets of tumors arising from stem and/or progenitor cells of the cerebellum. Recently ... Cancer
H01668 Neoplastic meningitis Neoplastic meningitis (NM) is a diffuse dissemination of tumor cells into the cerebrospinal fluid (CSF) and/or leptomeninges. NM is reported in patients with solid tumours (carcinomatous meningitis), haematological ... Nervous system disease
H01669 Secondary hyperparathyroidism Secondary hyperparathyroidism (SHPT) is a chronic and progressive disorder characterized by elevated serum parathyroid hormone (PTH), parathyroid gland hyperplasia, and disturbances in mineral metabolism ... Endocrine and metabolic disease
H01670 Social anxiety disorder
Social phobia
Social anxiety disorder (SAD) is the most common anxiety disorder. SAD is generally considered a chronic disorder and has its onset during early adolescence. It is a risk factor for subsequent depressive ... Mental and behavioural disorder
H01671 Neurosis
Neurotic disorder
Neurosis is a class of functional mental disorders involving distress but neither delusions nor hallucinations, whereby behavior is not outside socially acceptable norms. The state of research on neurosis ... Mental and behavioural disorder
H01672 Juvenile idiopathic arthritis Juvenile idiopathic arthritis (JIA) is one of the most common childhood rheumatic diseases. Clinically, it is defined as arthritis of unknown origin that starts before the age of 16, and persists for at ... Immune system disease
H01673 Palmoplantar keratoderma Palmoplantar keratodermas (PPK) comprise a heterogeneous group of keratinization disorders with hyperkeratotic thickening of palms and soles. Sporadic or acquired forms of PPKs and hereditary forms exist ... Congenital malformation
H01674 Ankylosing spondylitis
Bechterew disease
Ankylosing spondylitis (AS), formerly also known as Bechterew's disease, is a rheumatic disease of the axial skeleton that mainly affects the spine and the sacroiliac joint in the pelvis. AS is one of ... Musculoskeletal disease
H01675 Syringomyelia Syringomyelia is a spinal disorder characterized by the presence of abnormal fluid-filled cavities within the spinal cord. Early symptoms include headache, altered pain and temperature sensation, and paresthesia ... Congenital malformation
H01676 Normal pressure hydrocephalus Normal pressure hydrocephalus (NPH) is a progressive brain disease characterized by gait impairment, urinary incontinence, and dementia, and by ventricular enlargement in the absence of elevated intracranial ... Nervous system disease
H01677 Congenital hydrocephalus Congenital hydrocephalus (HYC) is a common birth defect in the circulation of the cerebrospinal fluid (CSF). It is characterized by ventricular dilatation. Although commonly considered a single disorder ... Congenital malformation
H01678 Dandy-Walker syndrome Dandy-Walker syndrome (DWS) is a congenital brain malformation, characterized by posterior fossa cyst, cystic dilatation of the fourth ventricle, cerebellar vermis dysgenesis, and an upwardly displaced ... Congenital malformation
H01679 Intrahepatic lithiasis
Intrahepatic calculosis
Hepatolithiasis
Intrahepatic lithiasis is very common disease in East Asia, characterized by the recurrent pyogenic cholangitis. The main clinical symptoms are abdominal pain, fever and jaundice. Pathologically, the intrahepatic ... Digestive system disease
H01680 Chronic pancreatitis Chronic pancreatitis is a progressive inflammatory disease of the pancreas that will finally result in both exocrine and endocrine insufficiency. Chronic pancreatitis develops gradually and worsens over ... Digestive system disease
H01681 Acute pancreatitis Acute pancreatitis ranges from a mild, self- limiting disease to a life-threatening condition with multiple organ failure. Abdominal pain is the predominant symptom. Nausea and vomiting may accompany the ... Digestive system disease
H01682 Syndrome of inappropriate antidiuretic hormone secretion The syndrome of inappropriate antidiuretic hormone secretion (SIADH) is an endocrine disease, characterized by inappropriately concentrated urine, dilutional hyponatremia, and subsequent manifestations ... Endocrine and metabolic disease
H01683 Disorders of antidiuretic hormone (ADH) secretion Water imbalance is common among the critically ill. The excessive increases or decreases in body water can be lethal. There are numerous pathologic and iatrogenic causes for water imbalance, the most troublesome ... Endocrine and metabolic disease
H01684 Primary sclerosing cholangitis Primary sclerosing cholangitis (PSC) is a rare progressive disease of the liver characterized by cholestasis and bile duct fibrosis, leading to decreased quality of life, cirrhosis, and the need for liver ... Digestive system disease
H01685 Autoimmune hepatitis Autoimmune hepatitis (AIH) is a chronic inflammatory liver disorder with an etiology that remains unclear. The pathogenesis may be a result of alterations in immune tolerance, a genetic predisposition ... Digestive system disease
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