KEGG   PATHWAY: bbub05166
Entry
bbub05166                   Pathway                                
Name
Human T-cell leukemia virus 1 infection - Bubalus bubalis (water buffalo)
Description
Human T-cell leukemia virus type 1 (HTLV-1) is a pathogenic retrovirus that is associated with adult T-cell leukemia/lymphoma (ATL). It is also strongly implicated in non-neoplastic chronic inflammatory diseases such as HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). Expression of Tax, a viral regulatory protein is critical to the pathogenesis. Tax is a transcriptional co-factor that interfere several signaling pathways related to anti-apoptosis or cell proliferation. The modulation of the signaling by Tax involve its binding to transcription factors like CREB/ATF, NF-kappa B, and SRF.
Class
Human Diseases; Infectious disease: viral
Pathway map
bbub05166  Human T-cell leukemia virus 1 infection
bbub05166

Organism
Bubalus bubalis (water buffalo) [GN:bbub]
Gene
102392377  SLC2A1; solute carrier family 2, facilitated glucose transporter member 1 isoform X1 [KO:K07299]
102400457  NRP1; neuropilin-1 isoform X4 [KO:K06724]
102402664  MYC; myc proto-oncogene protein isoform X1 [KO:K04377]
102406192  transformation/transcription domain-associated protein [KO:K08874]
102396976  KAT5; histone acetyltransferase KAT5 isoform X1 [KO:K11304] [EC:2.3.1.48]
102410004  CCND2; G1/S-specific cyclin-D2 [KO:K10151]
102412430  ITGAL; integrin alpha-L isoform X1 [KO:K05718]
102400120  ITGB2; integrin beta-2 isoform X1 [KO:K06464]
102412516  ICAM1; intercellular adhesion molecule 1 isoform X1 [KO:K06490]
112587129  GTPase HRas-like [KO:K02833]
102392995  KRAS; GTPase KRas isoform X2 [KO:K07827]
102399487  NRAS; GTPase NRas isoform X2 [KO:K07828]
102396842  MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 isoform X1 [KO:K04368] [EC:2.7.12.2]
102401744  MAP2K2; dual specificity mitogen-activated protein kinase kinase 2 isoform X1 [KO:K04369] [EC:2.7.12.2]
102396206  MAPK1; mitogen-activated protein kinase 1 isoform X1 [KO:K04371] [EC:2.7.11.24]
102403296  MAPK3; mitogen-activated protein kinase 3 [KO:K04371] [EC:2.7.11.24]
102413723  CD4; T-cell surface glycoprotein CD4 isoform X1 [KO:K06454]
102395333  TLN1; talin-1 isoform X4 [KO:K06271]
102416012  TLN2; talin-2 isoform X1 [KO:K06271]
123335143  RANBP3; ran-binding protein 3 isoform X9 [KO:K15304]
102415657  RAN; GTP-binding nuclear protein Ran [KO:K07936]
102397525  LOW QUALITY PROTEIN: GTP-binding nuclear protein Ran [KO:K07936]
112587779  GTP-binding nuclear protein Ran-like [KO:K07936]
102408122  XPO1; exportin-1 isoform X1 [KO:K14290]
102399346  calreticulin-like [KO:K08057]
102413610  CALR; calreticulin [KO:K08057]
102398705  calreticulin [KO:K08057]
102413795  CANX; calnexin [KO:K08054]
102400064  PPP3CA; serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X1 [KO:K04348] [EC:3.1.3.16]
102415631  PPP3CC; serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform isoform X1 [KO:K04348] [EC:3.1.3.16]
102414534  PPP3CB; serine/threonine-protein phosphatase 2B catalytic subunit beta isoform isoform X7 [KO:K04348] [EC:3.1.3.16]
102400804  PPP3R2; calcineurin subunit B type 2 [KO:K06268]
102413480  NFATC1; nuclear factor of activated T-cells, cytoplasmic 1 isoform X3 [KO:K04446]
102396612  NFATC2; nuclear factor of activated T-cells, cytoplasmic 2 isoform X5 [KO:K17332]
102390438  NFATC3; nuclear factor of activated T-cells, cytoplasmic 3 isoform X1 [KO:K17333]
102404650  NFATC4; nuclear factor of activated T-cells, cytoplasmic 4 isoform X1 [KO:K17334]
102391873  interleukin-2 receptor subunit beta [KO:K05069]
102392192  interleukin-2 receptor subunit beta [KO:K05069]
102402566  IL2RG; cytokine receptor common subunit gamma [KO:K05070]
102405285  JAK1; tyrosine-protein kinase JAK1 [KO:K11217] [EC:2.7.10.2]
102400750  JAK3; tyrosine-protein kinase JAK3 isoform X1 [KO:K11218] [EC:2.7.10.2]
102415442  signal transducer and activator of transcription 5A [KO:K11223]
102400858  signal transducer and activator of transcription 5B isoform X1 [KO:K11224]
102395421  IL2; interleukin-2 precursor [KO:K05429]
102393680  BOLA class I histocompatibility antigen, alpha chain BL3-7 [KO:K06751]
102394332  BOLA class I histocompatibility antigen, alpha chain BL3-6 [KO:K06751]
102410916  BOLA class I histocompatibility antigen, alpha chain BL3-7 isoform X3 [KO:K06751]
102412769  BOLA class I histocompatibility antigen, alpha chain BL3-7 isoform X3 [KO:K06751]
102394968  BOLA class I histocompatibility antigen, alpha chain BL3-7 isoform X1 [KO:K06751]
102390435  BOLA class I histocompatibility antigen, alpha chain BL3-6 isoform X1 [KO:K06751]
102398125  BOLA class I histocompatibility antigen, alpha chain BL3-7 isoform X2 [KO:K06751]
102402481  BOLA class I histocompatibility antigen, alpha chain BL3-7 isoform X1 [KO:K06751]
102413969  LOW QUALITY PROTEIN: BOLA class I histocompatibility antigen, alpha chain BL3-7 [KO:K06751]
102392615  H-2 class I histocompatibility antigen, Q10 alpha chain isoform X1 [KO:K06751]
102406719  LOW QUALITY PROTEIN: BOLA class I histocompatibility antigen, alpha chain BL3-7-like [KO:K06751]
102412126  BOLA class I histocompatibility antigen, alpha chain BL3-7-like [KO:K06751]
112587745  beta-2-microglobulin [KO:K08055]
112587746  beta-2-microglobulin [KO:K08055]
102391217  FDPS; farnesyl pyrophosphate synthase isoform X1 [KO:K00787] [EC:2.5.1.1 2.5.1.10]
102409656  VDAC1; voltage-dependent anion-selective channel protein 1 [KO:K05862]
102405012  SLC25A31; ADP/ATP translocase 4 [KO:K05863]
102413768  SLC25A4; ADP/ATP translocase 1 [KO:K05863]
102400898  SLC25A6; ADP/ATP translocase 3 [KO:K05863]
102415498  SLC25A5; ADP/ATP translocase 2 [KO:K05863]
102413761  ADP/ATP translocase 2-like [KO:K05863]
102391970  VDAC2; voltage-dependent anion-selective channel protein 2 [KO:K15040]
102400092  VDAC3; voltage-dependent anion-selective channel protein 3 isoform X2 [KO:K15041]
102389341  TSPO; translocator protein [KO:K05770]
102409200  VAC14; protein VAC14 homolog isoform X1 [KO:K15305]
102413631  MAD1L1; mitotic spindle assembly checkpoint protein MAD1 isoform X2 [KO:K06679]
112586263  MAD2L1; LOW QUALITY PROTEIN: mitotic spindle assembly checkpoint protein MAD2A [KO:K02537]
102416300  BUB1B; mitotic checkpoint serine/threonine-protein kinase BUB1 beta [KO:K06637] [EC:2.7.11.1]
102400333  BUB3; mitotic checkpoint protein BUB3 isoform X3 [KO:K02180]
102396508  ANAPC1; anaphase-promoting complex subunit 1 isoform X1 [KO:K03348]
102392759  ANAPC2; anaphase-promoting complex subunit 2 [KO:K03349]
102389770  CDC27; cell division cycle protein 27 homolog isoform X1 [KO:K03350]
102415084  ANAPC4; anaphase-promoting complex subunit 4 [KO:K03351]
102397136  ANAPC5; anaphase-promoting complex subunit 5 isoform X1 [KO:K03352]
102401483  CDC16; cell division cycle protein 16 homolog [KO:K03353]
102415730  ANAPC7; anaphase-promoting complex subunit 7 isoform X1 [KO:K03354]
102405130  CDC23; cell division cycle protein 23 homolog isoform X1 [KO:K03355]
102416566  ANAPC10; anaphase-promoting complex subunit 10 isoform X1 [KO:K03357]
102401972  ANAPC11; anaphase-promoting complex subunit 11 [KO:K03358]
102397540  CDC26; anaphase-promoting complex subunit CDC26 [KO:K03359]
102397735  ANAPC13; anaphase-promoting complex subunit 13 [KO:K12456]
102404816  anaphase-promoting complex subunit 13 [KO:K12456]
102392555  ANAPC15; anaphase-promoting complex subunit 15 isoform X1 [KO:K25228]
102393627  ANAPC16; anaphase-promoting complex subunit 16 [KO:K25229]
102409889  CDC20; cell division cycle protein 20 homolog [KO:K03363]
102415423  PTTG1; securin isoform X2 [KO:K06635]
102401554  ESPL1; separin isoform X1 [KO:K02365] [EC:3.4.22.49]
102398229  CCNB2; G2/mitotic-specific cyclin-B2 isoform X1 [KO:K21770]
102406954  CDKN2B; cyclin-dependent kinase 4 inhibitor B [KO:K04685]
102406311  cyclin-dependent kinase 4 inhibitor B isoform X2 [KO:K06621]
102412787  CDK4; cyclin-dependent kinase 4 [KO:K02089] [EC:2.7.11.22]
102411133  CCND1; G1/S-specific cyclin-D1 [KO:K04503]
102412107  CCND3; G1/S-specific cyclin-D3 isoform X1 [KO:K10152]
102403077  CDKN1A; cyclin-dependent kinase inhibitor 1 [KO:K06625]
102398715  CCNA2; cyclin-A2 [KO:K06627]
102408087  CCNA1; cyclin-A1 [KO:K06627]
102390852  CCNE2; G1/S-specific cyclin-E2 [KO:K06626]
102389005  CCNE1; G1/S-specific cyclin-E1 isoform X1 [KO:K06626]
102398457  CDK2; cyclin-dependent kinase 2 isoform X1 [KO:K02206] [EC:2.7.11.22]
102400134  RB1; retinoblastoma-associated protein [KO:K06618]
123464883  E2F1; transcription factor E2F1 [KO:K17454]
102403332  E2F2; transcription factor E2F2 [KO:K09389]
102394305  E2F3; transcription factor E2F3 isoform X1 [KO:K06620]
102399207  ATM; serine-protein kinase ATM isoform X2 [KO:K04728] [EC:2.7.11.1]
102411932  ATR; serine/threonine-protein kinase ATR isoform X1 [KO:K06640] [EC:2.7.11.1]
102398478  CHEK1; serine/threonine-protein kinase Chk1 isoform X1 [KO:K02216] [EC:2.7.11.1]
102409445  CHEK2; serine/threonine-protein kinase Chk2 isoform X1 [KO:K06641] [EC:2.7.11.1]
102402069  TP53; cellular tumor antigen p53 isoform X1 [KO:K04451]
102415109  PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
102404517  PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta isoform X1 [KO:K02649]
102395384  phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1 [KO:K02649]
102404165  PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
102400519  PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
102404610  PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
102397969  AKT1; RAC-alpha serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
102398761  AKT2; RAC-beta serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
102391021  AKT3; RAC-gamma serine/threonine-protein kinase isoform X4 [KO:K04456] [EC:2.7.11.1]
102396861  DLG1; disks large homolog 1 isoform X6 [KO:K12076]
102405361  PTEN; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
102392112  TNF; tumor necrosis factor isoform X1 [KO:K03156]
102398200  TNFRSF1A; tumor necrosis factor receptor superfamily member 1A [KO:K03158]
102399327  MAP3K1; mitogen-activated protein kinase kinase kinase 1 isoform X2 [KO:K04416] [EC:2.7.11.25]
102395178  MAP2K4; dual specificity mitogen-activated protein kinase kinase 4 isoform X4 [KO:K04430] [EC:2.7.12.2]
102393434  MAPK8; mitogen-activated protein kinase 8 isoform X2 [KO:K04440] [EC:2.7.11.24]
102396572  MAPK10; mitogen-activated protein kinase 10 isoform X2 [KO:K04440] [EC:2.7.11.24]
102403452  MAPK9; mitogen-activated protein kinase 9 isoform X5 [KO:K04440] [EC:2.7.11.24]
102405224  JUN; transcription factor AP-1 [KO:K04448]
102401163  MMP7; matrilysin isoform X2 [KO:K01397] [EC:3.4.24.23]
102402346  IL1R1; interleukin-1 receptor type 1 [KO:K04386]
102401594  IL1R2; interleukin-1 receptor type 2 [KO:K04387]
102388997  uncharacterized protein LOC102388997 [KO:K10784]
102390133  CD3D; T-cell surface glycoprotein CD3 delta chain [KO:K06450]
102390460  CD3E; T-cell surface glycoprotein CD3 epsilon chain [KO:K06451]
102388922  CD3G; T-cell surface glycoprotein CD3 gamma chain [KO:K06452]
102413611  MAP3K3; mitogen-activated protein kinase kinase kinase 3 isoform X4 [KO:K04421] [EC:2.7.11.25]
102399613  CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X3 [KO:K04467] [EC:2.7.11.10]
102398886  IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1 [KO:K07209] [EC:2.7.11.10]
102394706  IKBKG; NF-kappa-B essential modulator isoform X6 [KO:K07210]
102412626  NFKBIA; NF-kappa-B inhibitor alpha [KO:K04734]
102403930  NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X2 [KO:K02580]
102397938  RELA; transcription factor P65 [KO:K04735]
102410834  GPS2; G protein pathway suppressor 2 [KO:K15307]
102400684  LTBR; LOW QUALITY PROTEIN: tumor necrosis factor receptor superfamily member 3 [KO:K03159]
102395805  CD40; tumor necrosis factor receptor superfamily member 5 isoform X2 [KO:K03160]
102411220  TNFRSF13C; tumor necrosis factor receptor superfamily member 13C isoform X1 [KO:K05151]
102397755  MAP3K14; mitogen-activated protein kinase kinase kinase 14 [KO:K04466] [EC:2.7.11.25]
102392246  RELB; transcription factor RelB isoform X3 [KO:K09253]
102408345  NFKB2; nuclear factor NF-kappa-B p100 subunit isoform X1 [KO:K04469]
102405003  IL2RA; interleukin-2 receptor subunit alpha isoform X1 [KO:K05068]
102407360  IL15RA; interleukin-15 receptor subunit alpha isoform X1 [KO:K05074]
102415101  IL6; interleukin-6 isoform X1 [KO:K05405]
102413568  CSF2; granulocyte-macrophage colony-stimulating factor precursor [KO:K05427]
102391778  LTA; lymphotoxin-alpha [KO:K05468]
102416581  BCL2L1; bcl-2-like protein 1 [KO:K04570]
102411013  bcl-2-like protein 1 [KO:K04570]
102404023  E3 ubiquitin-protein ligase XIAP [KO:K04725] [EC:2.3.2.27]
102413660  TGFB1; transforming growth factor beta-1 proprotein isoform X2 [KO:K13375]
102390629  TGFB2; transforming growth factor beta-2 proprotein isoform X3 [KO:K13376]
102389416  TGFB3; transforming growth factor beta-3 proprotein [KO:K13377]
102396812  TGFBR1; TGF-beta receptor type-1 precursor [KO:K04674] [EC:2.7.11.30]
102415303  TGFBR2; TGF-beta receptor type-2 isoform X1 [KO:K04388] [EC:2.7.11.30]
102406564  SMAD2; mothers against decapentaplegic homolog 2 isoform X1 [KO:K04500]
102400710  SMAD3; mothers against decapentaplegic homolog 3 isoform X1 [KO:K23605]
102390834  SMAD4; mothers against decapentaplegic homolog 4 isoform X1 [KO:K04501]
102415323  ADCY1; adenylate cyclase type 1 [KO:K08041] [EC:4.6.1.1]
102412622  ADCY2; adenylate cyclase type 2 [KO:K08042] [EC:4.6.1.1]
102407976  ADCY3; adenylate cyclase type 3 isoform X1 [KO:K08043] [EC:4.6.1.1]
102408103  ADCY4; adenylate cyclase type 4 isoform X2 [KO:K08044] [EC:4.6.1.1]
102405387  ADCY5; adenylate cyclase type 5 [KO:K08045] [EC:4.6.1.1]
102407637  ADCY6; adenylate cyclase type 6 isoform X1 [KO:K08046] [EC:4.6.1.1]
102410456  ADCY7; adenylate cyclase type 7 isoform X1 [KO:K08047] [EC:4.6.1.1]
102395302  ADCY8; adenylate cyclase type 8 isoform X3 [KO:K08048] [EC:4.6.1.1]
102404282  ADCY9; adenylate cyclase type 9 [KO:K08049] [EC:4.6.1.1]
102392366  PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X1 [KO:K04345] [EC:2.7.11.11]
102413383  PRKACB; cAMP-dependent protein kinase catalytic subunit beta isoform X4 [KO:K04345] [EC:2.7.11.11]
102401072  NFYB; nuclear transcription factor Y subunit beta [KO:K08065]
102389605  SLA class II histocompatibility antigen, DQ haplotype D alpha chain [KO:K06752]
102408905  DLA class II histocompatibility antigen, DR-1 beta chain [KO:K06752]
102409438  SLA class II histocompatibility antigen, DQ haplotype D alpha chain [KO:K06752]
102409778  boLa class II histocompatibility antigen, DQB*0101 beta chain isoform X2 [KO:K06752]
102389065  DLA class II histocompatibility antigen, DR-1 beta chain isoform X2 [KO:K06752]
102389936  rano class II histocompatibility antigen, A beta chain isoform X1 [KO:K06752]
102390270  HLA class II histocompatibility antigen, DO beta chain isoform X1 [KO:K06752]
102392808  HLA class II histocompatibility antigen, DM beta chain [KO:K06752]
102393133  HLA class II histocompatibility antigen, DM alpha chain [KO:K06752]
102394631  HLA class II histocompatibility antigen, DO alpha chain isoform X1 [KO:K06752]
102407601  mamu class II histocompatibility antigen, DR alpha chain-like [KO:K06752]
112578753  H-2 class II histocompatibility antigen, E-S beta chain [KO:K06752]
102401997  SRF; serum response factor [KO:K04378]
102403895  ELK4; ETS domain-containing protein Elk-4 [KO:K04376]
112577626  ELK1; ETS domain-containing protein Elk-1 [KO:K04375]
102398044  SPI1; transcription factor PU.1 isoform X1 [KO:K09438]
102389408  ETS1; protein C-ets-1 isoform X5 [KO:K02678]
102394352  ETS2; protein C-ets-2 [KO:K21932]
102394310  TBPL2; TATA box-binding protein-like 2 isoform X1 [KO:K03120]
102395512  TATA-box-binding protein [KO:K03120]
102407125  TBPL1; TATA box-binding protein-like 1 [KO:K03120]
102408938  TATA-box-binding protein-like isoform X2 [KO:K03120]
102393791  FOS; proto-oncogene C-Fos [KO:K04379]
102398757  EGR1; early growth response protein 1 [KO:K09203]
102392078  FOSL1; fos-related antigen 1 [KO:K04502]
102394072  EGR2; E3 SUMO-protein ligase EGR2 isoform X1 [KO:K12496]
102401906  CREB1; cyclic AMP-responsive element-binding protein 1 isoform X1 [KO:K05870]
102406078  CREB3L1; cyclic AMP-responsive element-binding protein 3-like protein 1 isoform X1 [KO:K09048]
102395032  CREB3; cyclic AMP-responsive element-binding protein 3 [KO:K09048]
102400784  CREB3L3; cyclic AMP-responsive element-binding protein 3-like protein 3 isoform X1 [KO:K09048]
102416630  CREB3L2; cyclic AMP-responsive element-binding protein 3-like protein 2 [KO:K09048]
102398301  CREB3L4; cyclic AMP-responsive element-binding protein 3-like protein 4 isoform X2 [KO:K09048]
102410577  ATF2; cyclic AMP-dependent transcription factor ATF-2 isoform X1 [KO:K04450]
102393344  ATF4; cyclic AMP-dependent transcription factor ATF-4 [KO:K04374]
112580290  cyclic AMP-dependent transcription factor ATF-4-like [KO:K04374]
102400864  CREB5; cyclic AMP-responsive element-binding protein 5 isoform X4 [KO:K09047]
102392963  ATF6B; cyclic AMP-dependent transcription factor ATF-6 beta isoform X3 [KO:K09049]
102402466  CRTC1; CREB-regulated transcription coactivator 1 isoform X1 [KO:K15309]
102397007  CRTC2; CREB-regulated transcription coactivator 2 isoform X1 [KO:K16333]
102396979  CRTC3; CREB-regulated transcription coactivator 3 isoform X1 [KO:K16334]
102403750  CREB-binding protein isoform X1 [KO:K04498] [EC:2.3.1.48]
102394197  EP300; histone acetyltransferase p300 isoform X4 [KO:K04498] [EC:2.3.1.48]
102389863  KAT2A; histone acetyltransferase KAT2A isoform X1 [KO:K06062] [EC:2.3.1.48]
102412005  KAT2B; histone acetyltransferase KAT2B isoform X2 [KO:K06062] [EC:2.3.1.48]
102415632  TCF3; transcription factor E2-alpha isoform X1 [KO:K09063]
102399213  POLB; DNA polymerase beta isoform X2 [KO:K02330] [EC:2.7.7.7 4.2.99.-]
102406784  LCK; tyrosine-protein kinase Lck isoform X3 [KO:K05856] [EC:2.7.10.2]
102400076  BAX; apoptosis regulator BAX isoform X1 [KO:K02159]
102396473  CDKN2C; cyclin-dependent kinase 4 inhibitor C [KO:K06622]
102388955  TERT; telomerase reverse transcriptase isoform X1 [KO:K11126] [EC:2.7.7.49]
102404283  MSX2; homeobox protein MSX-2 [KO:K09341]
102407579  MSX1; homeobox protein MSX-1 isoform X1 [KO:K09341]
123331302  homeobox protein MSX-2-like isoform X2 [KO:K09341]
Compound
C00027  Hydrogen peroxide
C00076  Calcium cation
C00238  Potassium cation
C00575  3',5'-Cyclic AMP
C05981  Phosphatidylinositol-3,4,5-trisphosphate
Reference
PMID:17384582
  Authors
Matsuoka M, Jeang KT
  Title
Human T-cell leukaemia virus type 1 (HTLV-1) infectivity and cellular transformation.
  Journal
Nat Rev Cancer 7:270-80 (2007)
DOI:10.1038/nrc2111
Reference
PMID:16155604
  Authors
Grassmann R, Aboud M, Jeang KT
  Title
Molecular mechanisms of cellular transformation by HTLV-1 Tax.
  Journal
Oncogene 24:5976-85 (2005)
DOI:10.1038/sj.onc.1208978
Reference
PMID:18702816
  Authors
Boxus M, Twizere JC, Legros S, Dewulf JF, Kettmann R, Willems L
  Title
The HTLV-1 Tax interactome.
  Journal
Retrovirology 5:76 (2008)
DOI:10.1186/1742-4690-5-76
Reference
PMID:21994754
  Authors
Jones KS, Lambert S, Bouttier M, Benit L, Ruscetti FW, Hermine O, Pique C
  Title
Molecular aspects of HTLV-1 entry: functional domains of the HTLV-1 surface subunit (SU) and their relationships to the entry receptors.
  Journal
Viruses 3:794-810 (2011)
DOI:10.3390/v3060794
Reference
PMID:21114861
  Authors
Ghez D, Lepelletier Y, Jones KS, Pique C, Hermine O
  Title
Current concepts regarding the HTLV-1 receptor complex.
  Journal
Retrovirology 7:99 (2010)
DOI:10.1186/1742-4690-7-99
Reference
  Authors
Sinet F.
  Title
Complex splicing in the human T-cell leukemia virus (HTLV) family of retroviruses: a number of proteins play a key role in the establishment and maintenance of viral infection.
  Journal
BioSciences Master Reviews, July 2013
Reference
PMID:18923409
  Authors
Sattentau Q
  Title
Avoiding the void: cell-to-cell spread of human viruses.
  Journal
Nat Rev Microbiol 6:815-26 (2008)
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Related
pathway
bbub03013  Nucleocytoplasmic transport
bbub04010  MAPK signaling pathway
bbub04064  NF-kappa B signaling pathway
bbub04110  Cell cycle
bbub04115  p53 signaling pathway
bbub04151  PI3K-Akt signaling pathway
bbub04210  Apoptosis
bbub04350  TGF-beta signaling pathway
bbub04612  Antigen processing and presentation
bbub04660  T cell receptor signaling pathway
bbub04668  TNF signaling pathway
KO pathway
ko05166   
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