KEGG   ORTHOLOGY: K04431
Entry
K04431                      KO                                     

Name
MAP2K7, MKK7
Definition
mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
Pathway
ko04010  MAPK signaling pathway
ko04012  ErbB signaling pathway
ko04013  MAPK signaling pathway - fly
ko04141  Protein processing in endoplasmic reticulum
ko04214  Apoptosis - fly
ko04361  Axon regeneration
ko04380  Osteoclast differentiation
ko04530  Tight junction
ko04620  Toll-like receptor signaling pathway
ko04624  Toll and Imd signaling pathway
ko04660  T cell receptor signaling pathway
ko04664  Fc epsilon RI signaling pathway
ko04668  TNF signaling pathway
ko04722  Neurotrophin signaling pathway
ko04912  GnRH signaling pathway
ko04926  Relaxin signaling pathway
ko05010  Alzheimer disease
ko05016  Huntington disease
ko05022  Pathways of neurodegeneration - multiple diseases
ko05132  Salmonella infection
ko05135  Yersinia infection
ko05161  Hepatitis B
ko05167  Kaposi sarcoma-associated herpesvirus infection
ko05169  Epstein-Barr virus infection
ko05170  Human immunodeficiency virus 1 infection
ko05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
   04013 MAPK signaling pathway - fly
    K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
   04012 ErbB signaling pathway
    K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
   04668 TNF signaling pathway
    K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
 09140 Cellular Processes
  09143 Cell growth and death
   04214 Apoptosis - fly
    K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
  09144 Cellular community - eukaryotes
   04530 Tight junction
    K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
   04624 Toll and Imd signaling pathway
    K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
   04660 T cell receptor signaling pathway
    K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
   04664 Fc epsilon RI signaling pathway
    K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
  09152 Endocrine system
   04912 GnRH signaling pathway
    K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
   04926 Relaxin signaling pathway
    K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
  09158 Development and regeneration
   04361 Axon regeneration
    K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
   04380 Osteoclast differentiation
    K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
   05016 Huntington disease
    K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
   05022 Pathways of neurodegeneration - multiple diseases
    K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
   05135 Yersinia infection
    K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
   05161 Hepatitis B
    K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
   05167 Kaposi sarcoma-associated herpesvirus infection
    K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
   05169 Epstein-Barr virus infection
    K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
Protein kinases [BR:ko01001]
 Serine/threonine kinases: STE group
  STE7 family
   K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
Other DBs
GO: 0004708
Genes
HSA: 5609(MAP2K7)
PTR: 743199(MAP2K7)
PPS: 100989537(MAP2K7)
GGO: 101124339(MAP2K7)
PON: 100431600(MAP2K7)
NLE: 100587140(MAP2K7)
MCC: 710077(MAP2K7)
MCF: 102126975(MAP2K7)
CSAB: 103233823(MAP2K7)
RRO: 104679497(MAP2K7)
RBB: 108534524(MAP2K7)
CJC: 100412930(MAP2K7)
SBQ: 101047840(MAP2K7)
MMU: 26400(Map2k7)
MCAL: 110299603(Map2k7)
MPAH: 110336400(Map2k7)
RNO: 363855(Map2k7)
CGE: 100754421(Map2k7)
NGI: 103726522(Map2k7)
HGL: 101710666(Map2k7)
CCAN: 109698434(Map2k7)
OCU: 103345313(MAP2K7)
TUP: 102500732(MAP2K7)
CFA: 485004(MAP2K7)
VVP: 112909663(MAP2K7)
AML: 100475975(MAP2K7)
UMR: 103681888(MAP2K7)
UAH: 113242915(MAP2K7)
ORO: 101382078(MAP2K7)
ELK: 111161723
FCA: 101095157(MAP2K7)
PTG: 102949140(MAP2K7)
PPAD: 109254200(MAP2K7)
AJU: 106970785(MAP2K7)
BTA: 787278(MAP2K7)
BOM: 102272638(MAP2K7)
BIU: 109560948(MAP2K7)
BBUB: 102404881(MAP2K7)
CHX: 102173178(MAP2K7)
OAS: 100302082(MAP2K7)
SSC: 100520418(MAP2K7)
CFR: 102506459(MAP2K7)
CDK: 105087572(MAP2K7)
BACU: 103011683(MAP2K7)
LVE: 103091499(MAP2K7)
OOR: 101288079(MAP2K7)
DLE: 111166011(MAP2K7)
PCAD: 102991774(MAP2K7)
ECB: 100147230(MAP2K7)
EPZ: 103543808(MAP2K7)
EAI: 106844503(MAP2K7)
MYB: 102247950(MAP2K7)
MYD: 102760954(MAP2K7)
MNA: 107529906(MAP2K7)
HAI: 109396087(MAP2K7)
DRO: 112305131(MAP2K7)
PALE: 102892533(MAP2K7)
RAY: 107519926(MAP2K7)
MJV: 108409616(MAP2K7)
LAV: 100673238(MAP2K7)
TMU: 101346746
MDO: 100026752(MAP2K7)
SHR: 100926110(MAP2K7)
PCW: 110202112(MAP2K7)
OAA: 100089737(MAP2K7)
GGA: 107050551
CJO: 107307804
NMEL: 110390478(MAP2K7)
LSR: 110480664(MAP2K7)
GFR: 102038813(MAP2K7)
FAB: 101812216
PHI: 102100701(MAP2K7)
PMAJ: 107198843(MAP2K7)
CCAE: 111922673(MAP2K7)
FPG: 101924219(MAP2K7)
FCH: 102048069
ASN: 102372350(MAP2K7)
AMJ: 102562496(MAP2K7)
PSS: 102463924(MAP2K7)
CMY: 102932325(MAP2K7)
CPIC: 101931768(MAP2K7)
ACS: 100566152(map2k7)
PVT: 110082669(MAP2K7)
PBI: 103066234(MAP2K7)
PMUR: 107291150(MAP2K7)
TSR: 106547907(MAP2K7)
PMUA: 114590811(MAP2K7)
GJA: 107117671(MAP2K7)
XLA: 108712658 394391(map2k7.S)
XTR: 613115(map2k7)
NPR: 108790540(MAP2K7)
DRE: 560913(map2k7)
SGH: 107567797(map2k7) 107602992
CCAR: 109066210
IPU: 108258614(map2k7)
PHYP: 113537632(map2k7)
AMEX: 103024363(map2k7)
EEE: 113580330(map2k7)
TRU: 101064650(map2k7)
LCO: 104934939(map2k7)
NCC: 104951572(map2k7)
MZE: 101475777(map2k7)
ONL: 100705501(map2k7)
OLA: 101164950(map2k7)
XMA: 102238025(map2k7)
XCO: 114144382(map2k7)
PRET: 103467648(map2k7)
CVG: 107101318(map2k7)
NFU: 107382265(map2k7)
KMR: 108242723(map2k7)
ALIM: 106515295(map2k7)
AOCE: 111564211(map2k7)
CSEM: 103383563(map2k7)
POV: 109627519(map2k7)
LCF: 108875834(map2k7)
SDU: 111236339(map2k7)
SLAL: 111659787(map2k7)
HCQ: 109511101(map2k7)
BPEC: 110166191(map2k7)
MALB: 109966260(map2k7)
ELS: 105021508(map2k7)
SFM: 108939797(map2k7)
PKI: 111833549(map2k7)
LCM: 102365163(MAP2K7)
RTP: 109911816(map2k7)
BFO: 118420702
CIN: 778674(mapkk7)
SPU: 591137
APLC: 110986882
SKO: 100376238
DME: Dmel_CG4353(hep)
DER: 6551002
DSE: 6618620
DSI: Dsimw501_GD15909(Dsim_GD15909)
DAN: 6503566
DSR: 110183528
DPE: 6597692
DMN: 108164891
DWI: 6648557
DAZ: 108620344
DNV: 108656874
DHE: 111593442
DVI: 6633831
MDE: 101892997
LCQ: 111679763
AAG: 5578019
AME: 413389
BIM: 100740833
BTER: 100631092
CCAL: 108623498
OBB: 114873219
SOC: 105195984
MPHA: 105833681
AEC: 105151228
ACEP: 105619941
PBAR: 105424720
VEM: 105568514
HST: 105185444
DQU: 106745527
CFO: 105252678
LHU: 105675778
PGC: 109857214
OBO: 105285129
PCF: 106787706
NVI: 100121060
CSOL: 105368763
MDL: 103573420
TCA: 103315236(hep)
DPA: 109543217
ATD: 109609105
NVL: 108566466
BMOR: 100862753
BMAN: 114242559
PMAC: 106711754
PRAP: 111002093
HAW: 110379828
TNL: 113494585
API: 100165019
DNX: 107167783
AGS: 114127951
RMD: 113551935
BTAB: 109034576
CLEC: 106668141
ZNE: 110838369
FCD: 110847803
TUT: 107371332
DPTE: 113793114
CSCU: 111640167
PTEP: 107450140
CEL: CELE_K08A8.1(mek-1)
CBR: CBG16698(Cbr-mek-1)
BMY: Bm1_27865
PCAN: 112575282
CRG: 105339236
MYI: 110464981
OBI: 106868012
SHX: MS3_07524
EGL: EGR_04146
NVE: 5515320
EPA: 110244754
ADF: 107332902
AMIL: 114947543
PDAM: 113681688
SPIS: 111326634
DGT: 114518977
HMG: 100201328
AQU: 100640493
 » show all
Reference
PMID:9372971
  Authors
Wu Z, Wu J, Jacinto E, Karin M
  Title
Molecular cloning and characterization of human JNKK2, a novel Jun NH2-terminal kinase-specific kinase.
  Journal
Mol Cell Biol 17:7407-16 (1997)
DOI:10.1128/MCB.17.12.7407
  Sequence
[hsa:5609]
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