Entry |
|
Name |
Epinephrine (USP/INN); Adrenaline (JP17); Adrenalin (TN); Auvi-q (TN); Epipen (TN) |
Product |
ADRENALIN (EPINEPHRINE) (HF Acquisition Co LLC), ADRENALIN(R) (HF Acquisition Co LLC), EPINEPHRINE (BPI Labs), EPINEPHRINE (Belcher Pharmaceuticals), EPINEPHRINE (General Injectables and Vaccines), EPINEPHRINE (HF Acquisition Co LLC), EPINEPHRINE (HF Acquisition Co LLC), EPINEPHRINE (HF Acquisition Co LLC), EPINEPHRINE CONVENIENCE KIT (HF Acquisition Co LLC), EPINEPHRINE (Medical Purchasing Solutions), AUVI-Q (Medical Purchasing Solutions), AUVI-Q (Medical Purchasing Solutions), ADRENALIN (Medical Purchasing Solutions), EPINEPHRINE (Mylan Specialty L.P.), ADRENALIN (Par Pharmaceutical), ADRENALIN (Par Pharmaceutical), ADRENALIN (Par Pharmaceutical), EPIPEN (REMEDYREPACK), SYMJEPI (USWM), AUVI-Q (kaleo), EPINEPHRINE PROFESSIONAL (Focus Health Group), CERTA DOSE EPINEPHRINE CONVENIENCE KIT (Certa Dose), EPINEPHRINE PROFESSIONAL EMS (Focus Health Group), EPINEPHRINESNAP-EMS (Snap Medical Industries), EPINEPHRINESNAP-V (Snap Medical Industries), ADRENALIN (General Injectables and Vaccines) |
Generic |
EPINEPHRINE (A-S Medication Solutions), EPINEPHRINE (A-S Medication Solutions), EPINEPHRINE (A-S Medication Solutions), EPINEPHRINE (Amneal Pharmaceuticals of New York LLC), EPINEPHRINE (Asclemed USA), EPINEPHRINE (AvKARE), EPINEPHRINE (HF Acquisition Co LLC), EPINEPHRINE (International Medication Systems), EPINEPHRINE (Medical Purchasing Solutions), EPINEPHRINE (Medical Purchasing Solutions), EPINEPHRINE (Medical Purchasing Solutions), EPINEPHRINE (Medical Purchasing Solutions), EPINEPHRINE (Mylan Specialty L.P.), EPINEPHRINE (REMEDYREPACK), EPINEPHRINE (REMEDYREPACK), EPINEPHRINE (Teva Pharmaceuticals USA) |
Formula |
C9H13NO3
|
Exact mass |
183.0895
|
Mol weight |
183.2044
|
Structure |

|
Simcomp |
|
Class |
Cardiovascular agent
DG01703 Cardiotonic
DG01699 Catecholamine cardiotonic
DG01456 Adrenergic receptor agonist
DG01450 alpha-Adrenergic receptor agonist
DG01448 alpha1-Adrenergic receptor agonist
DG01449 alpha2-Adrenergic receptor agonist
DG01455 beta-Adrenergic receptor agonist
DG01451 beta1-Adrenergic receptor agonist
DG01452 beta2-Adrenergic receptor agonist
DG01453 beta3-Adrenergic receptor agonist
DG01951 Catecholamine adrenergic receptor agonist
DG01592 COMT substrate
Metabolizing enzyme substrate
DG02917 MAO substrate
|
Remark |
Therapeutic category: | 2451 |
Product (DG00013): | D00095<JP/US> |
Product (mixture): | D04052<JP/US> D11290<US> D11569<US> |
|
Efficacy |
Bronchodilator, Vasoconstrictor, Adrenergic receptor agonist |
Disease |
|
Comment |
Catecholamine derivative
|
Target |
|
Pathway |
hsa04080 | Neuroactive ligand-receptor interaction |
hsa04261 | Adrenergic signaling in cardiomyocytes |
hsa04270 | Vascular smooth muscle contraction |
|
Metabolism |
|
Interaction |
|
Structure map |
map07214 | beta-Adrenergic receptor agonists/antagonists |
|
Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A01 STOMATOLOGICAL PREPARATIONS
A01A STOMATOLOGICAL PREPARATIONS
A01AD Other agents for local oral treatment
A01AD01 Epinephrine
D00095 Epinephrine (USP/INN) <JP/US>
B BLOOD AND BLOOD FORMING ORGANS
B02 ANTIHEMORRHAGICS
B02B VITAMIN K AND OTHER HEMOSTATICS
B02BC Local hemostatics
B02BC09 Epinephrine
D00095 Epinephrine (USP/INN) <JP/US>
C CARDIOVASCULAR SYSTEM
C01 CARDIAC THERAPY
C01C CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES
C01CA Adrenergic and dopaminergic agents
C01CA24 Epinephrine
D00095 Epinephrine (USP/INN) <JP/US>
R RESPIRATORY SYSTEM
R01 NASAL PREPARATIONS
R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
R01AA Sympathomimetics, plain
R01AA14 Epinephrine
D00095 Epinephrine (USP/INN) <JP/US>
R03 DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
R03A ADRENERGICS, INHALANTS
R03AA Alpha- and beta-adrenoreceptor agonists
R03AA01 Epinephrine
D00095 Epinephrine (USP/INN) <JP/US>
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01E ANTIGLAUCOMA PREPARATIONS AND MIOTICS
S01EA Sympathomimetics in glaucoma therapy
S01EA01 Epinephrine
D00095 Epinephrine (USP/INN) <JP/US>
USP drug classification [BR:br08302]
Respiratory Tract/Pulmonary Agents
Bronchodilators, Sympathomimetic
Epinephrine
D00095 Epinephrine (USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
24 Hormones
245 Adrenal hormone preparations
2451 Epinephrines
D00095 Epinephrine (USP/INN); Adrenaline (JP17)
Risk category of Japanese OTC drugs [BR:br08312]
Second-class OTC drugs
Inorganic and organic chemicals
Adrenaline (Epinephrine)
D00095 Epinephrine (USP/INN)
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRA1
D00095 Epinephrine (USP/INN) <JP/US>
ADRA2
D00095 Epinephrine (USP/INN) <JP/US>
ADRB
D00095 Epinephrine (USP/INN) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00095 Adrenaline
D00095 Adrenaline solution
D00095 Adrenaline injection
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D00095
Prodrugs [br08324.html]
D00095
|
Other DBs |
|
LinkDB |
|
KCF data |
ATOM 13
1 C8y C 21.2028 -17.0133
2 C8x C 21.2028 -18.4284
3 C8x C 19.9857 -16.3144
4 C1c C 22.4083 -16.3144
5 C8x C 19.9857 -19.1389
6 C8y C 18.7742 -17.0133
7 C1b C 23.6196 -17.0075
8 O1a O 22.4083 -14.9168
9 C8y C 18.7742 -18.4284
10 N1b N 24.8191 -16.3087
11 O1a O 17.5630 -19.1156
12 O1a O 17.5677 -16.3165
13 C1a C 26.0284 -17.0006
BOND 13
1 1 3 1
2 1 4 1
3 2 5 1
4 3 6 2
5 4 7 1
6 4 8 1 #Up
7 5 9 2
8 7 10 1
9 9 11 1
10 6 9 1
11 6 12 1
12 1 2 2
13 10 13 1
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