KEGG   GLYCAN: G00050
Entry
G00050                      Glycan                                 
Name
Paragloboside;
Lactoneotetraosylceramide;
Lacto-N-neotetraosylceramide;
Neolactotetraosylceramide;
LA1;
nLcCer;
nLc4Cer
Composition
(Gal)2 (Glc)1 (GlcNAc)1 (Cer)1
Mass
689.6 (Cer)
Structure
Remark
Same as: C04922
Reaction
R05975 R05977 R05978 R06013 R06024 R06025 R06026 R06215
R11375 R11378
Pathway
map00601  Glycosphingolipid biosynthesis - lacto and neolacto series
map01100  Metabolic pathways
Module
M00071  Glycosphingolipid biosynthesis, neolacto-series, LacCer => nLc4Cer
Network
nt06035  Blood group carbohydrate antigen biosynthesis
Enzyme
2.4.1.65        2.4.1.69        2.4.1.79        2.4.1.87        
2.4.1.149       2.4.1.150       2.4.1.152       2.4.1.228       
2.4.1.275       2.4.1.-         2.4.3.6         2.4.99.-
Brite
Lipids [BR:br08002]
 SP  Sphingolipids
  SP05 Neutral glycosphingolipids
   SP0505 Galbeta1-4GlcNAcbeta1-3Galbeta1-4Glc- (Neolacto series)
    G00050  Gal-beta1->4GlcNAc-beta1->3Gal-beta1->4Glc-beta1->1'Cer (nLcCer)
Cancer-associated carbohydrates [br08441.html]
 Glycosphingolipid
  G00050
Reference
1  [PMID:2960671]
  Authors
Holmes EH, Hakomori S, Ostrander GK.
  Title
Synthesis of type 1 and 2 lacto series glycolipid antigens in human colonic adenocarcinoma and derived cell lines is due to activation of a normally unexpressed beta 1----3N-acetylglucosaminyltransferase.
  Journal
J Biol Chem 262:15649-58 (1987)
Other DBs
CCSD: 
GlyTouCan: G58896AZ
LIPIDMAPS: LMSP0505AA00
JCGGDB: JCGG-STR026439
GlycoEpitope: EP0068 EP0075 EP0140 EP0350
LinkDB
KCF data

NODE        5
            1   Cer        13     0
            2   Glc         5     0
            3   Gal        -3     0
            4   GlcNAc    -12     0
            5   Gal       -21     0
EDGE        4
            1     2:b1    1:1  
            2     3:b1    2:4  
            3     4:b1    3:3  
            4     5:b1    4:4

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