KEGG    Network variation - Blood group carbohydrate antigen biosynthesis
[ Network menu | Network entry | Help ]
ENTRYnt06035
NameBlood group carbohydrate antigen biosynthesis
CategoryPathway view; Glycan/glycoprotein metabolism
Pathwayhsa00601 Glycosphingolipid biosynthesis - lacto and neolacto series
hsa00603 Glycosphingolipid biosynthesis - globo and isoglobo series
Modulehsa_M00070 Glycosphingolipid biosynthesis, lacto-series, LacCer => Lc4Cer
hsa_M00071 Glycosphingolipid biosynthesis, neolacto-series, LacCer => nLc4Cer
hsa_M00068 Glycosphingolipid biosynthesis, globo-series, LacCer => Gb4Cer
Britebr08110 
Display drug-target relation   disease type
N01651    LacCer−B3GNT5⇉B3GALT1/2/5→Lc4Cer−FUT2*H→TypeIH⌿ABO*O
N01689          Lc4Cer⌿FUT2*H-
 
N01652              TypeIH−ABO*A→TypeIA
N01653              TypeIH−ABO*B→TypeIB
N01664                  [TypeIA,TypeIB]−FUT3*Le→[ALeb,BLeb]
 
N01659          TypeIH−FUT3*Le→Leb
N01660          Lc4Cer−FUT3*Le→Lea
N01661      Lc4Cer−ST3GAL3/4→sLc4Cer−FUT3*Le→SLea
N01700          [TypeIH,Lc4Cer,sLc..⌿FUT3*Le-
 
N01666    LacCer−B3GNT5⇉B4GALT1/2/3/4→nLc4Cer−FUT1*H→TypeIIH⌿ABO*O
N01683          nLc4Cer⌿FUT1*H-
 
N01667              TypeIIH−ABO*A→TypeIIA
N01668              TypeIIH−ABO*B→TypeIIB
N01669                  [TypeIIA,TypeIIB]−FUT3*Le→[ALey,BLey]
N01670                  Gal-TypeIIA−FUT1/2→TypeIIIH−ABO*A→TypeIIIA
 
N01673          TypeIIH−FUT3/4/5/6/9→Ley
N01672          nLc4Cer−FUT3/4/5/6/9→Lex
N01674      nLc4Cer−ST3GAL6→snLc4Cer−FUT3/4/5/6/7→SLex
 
N00824      GDP-Fuc−SLC35C1→GDP-Fuc(Golgi)
    CDG-IIc     SLC35C1*
 
N01675          snLc4Cer−B4GALNT2*SID1→Sda
N01702          snLc4Cer⌿B4GALNT2*Sda-
 
N01678          nLc4Cer−B3GNT2/3/4⇉B4GALT1/3/4→i_antigen−GCNT2*I→I_antigen
N01704                i_antigen⌿GCNT2*I-
 
N01676          nLc4Cer−A4GALT*P1/NOR→P1
N01699          nLc4Cer⌿A4GALT*P1-/p
 
N01677          nLc4Cer−B3GALNT1*P→PX2
N01679      LacCer−A4GALT*P1→Pk−B3GALNT1*P→P⌿GBGT1*Fs-
N01654              P−GBGT1*Fs→Forssman
N01680      LacCer−A4GALT*NOR→Pk−B3GALNT1*P→P−A4GALT*NOR→NOR1−B3GALNT1*P→NORint−A4GALT*NOR→NOR2
N01698      LacCer⌿A4GALT*p
N01697          Pk⌿B3GALNT1*P-
 
N01690              P−B3GALT5→Gb5Cer−FUT1/2*H→TypeIVH(Globo-H)⌿ABO*O/A2
N01682                      TypeIVH(Globo-H)−ABO*A→TypeIVA(Globo-A)
N01703                      TypeIVH(Globo-H)−ABO*B→TypeIVB(Globo-B)

Disease nameDisease category
CDG-IIcH00119Congenital disorders of glycosylation type IIInherited metabolic disorder