Homo sapiens (human): 4804
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Entry
4804 CDS
T01001
Symbol
NGFR, CD271, Gp80-LNGFR, TNFRSF16, p75(NTR), p75NTR
Name
(RefSeq) nerve growth factor receptor
KO
K02583
tumor necrosis factor receptor superfamily member 16
Organism
hsa
Homo sapiens (human)
Pathway
hsa03265
Virion - Ebolavirus, Lyssavirus and Morbillivirus
hsa04010
MAPK signaling pathway
hsa04014
Ras signaling pathway
hsa04015
Rap1 signaling pathway
hsa04060
Cytokine-cytokine receptor interaction
hsa04151
PI3K-Akt signaling pathway
hsa04215
Apoptosis - multiple species
hsa04722
Neurotrophin signaling pathway
hsa05202
Transcriptional misregulation in cancer
Network
nt06240
Transcription (cancer)
nt06526
MAPK signaling
nt06530
PI3K signaling
Element
N00132
Amplified MYCN to transcriptional repression
N01592
GF-RTK-RAS-ERK signaling pathway
N01599
Regulation of GF-RTK-RAS-ERK signaling, ubiquitination of RTK by CBL
N01656
GF-RTK-PI3K signaling pathway
N01658
GF-RTK-RAS-PI3K signaling pathway
Drug target
Cenegermin:
D11028
<US>
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09125 Information processing in viruses
03265 Virion - Ebolavirus, Lyssavirus and Morbillivirus
4804 (NGFR)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
4804 (NGFR)
04014 Ras signaling pathway
4804 (NGFR)
04015 Rap1 signaling pathway
4804 (NGFR)
04151 PI3K-Akt signaling pathway
4804 (NGFR)
09133 Signaling molecules and interaction
04060 Cytokine-cytokine receptor interaction
4804 (NGFR)
09140 Cellular Processes
09143 Cell growth and death
04215 Apoptosis - multiple species
4804 (NGFR)
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
4804 (NGFR)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
4804 (NGFR)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04050 Cytokine receptors [BR:
hsa04050
]
4804 (NGFR)
04090 CD molecules [BR:
hsa04090
]
4804 (NGFR)
Cytokine receptors [BR:
hsa04050
]
Tumor necrosis factor receptors
TNF receptor superfamily
4804 (NGFR)
CD molecules [BR:
hsa04090
]
Proteins
4804 (NGFR)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
TNFR_16_TM
TNFR_c6
Death
DUF6931
bDLD3
TPR_21
Motif
Other DBs
NCBI-GeneID:
4804
NCBI-ProteinID:
NP_002498
OMIM:
162010
HGNC:
7809
Ensembl:
ENSG00000064300
UniProt:
P08138
Structure
PDB
LinkDB
All DBs
Position
17:49495293..49515008
Genome browser
AA seq
427 aa
AA seq
DB search
MGAGATGRAMDGPRLLLLLLLGVSLGGAKEACPTGLYTHSGECCKACNLGEGVAQPCGAN
QTVCEPCLDSVTFSDVVSATEPCKPCTECVGLQSMSAPCVEADDAVCRCAYGYYQDETTG
RCEACRVCEAGSGLVFSCQDKQNTVCEECPDGTYSDEANHVDPCLPCTVCEDTERQLREC
TRWADAECEEIPGRWITRSTPPEGSDSTAPSTQEPEAPPEQDLIASTVAGVVTTVMGSSQ
PVVTRGTTDNLIPVYCSILAAVVVGLVAYIAFKRWNSCKQNKQGANSRPVNQTPPPEGEK
LHSDSGISVDSQSLHDQQPHTQTASGQALKGDGGLYSSLPPAKREEVEKLLNGSAGDTWR
HLAGELGYQPEHIDSFTHEACPVRALLASWATQDSATLDALLAALRRIQRADLVESLCSE
STATSPV
NT seq
1284 nt
NT seq
+upstream
nt +downstream
nt
atgggggcaggtgccaccggccgcgccatggacgggccgcgcctgctgctgttgctgctt
ctgggggtgtcccttggaggtgccaaggaggcatgccccacaggcctgtacacacacagc
ggtgagtgctgcaaagcctgcaacctgggcgagggtgtggcccagccttgtggagccaac
cagaccgtgtgtgagccctgcctggacagcgtgacgttctccgacgtggtgagcgcgacc
gagccgtgcaagccgtgcaccgagtgcgtggggctccagagcatgtcggcgccgtgcgtg
gaggccgacgacgccgtgtgccgctgcgcctacggctactaccaggatgagacgactggg
cgctgcgaggcgtgccgcgtgtgcgaggcgggctcgggcctcgtgttctcctgccaggac
aagcagaacaccgtgtgcgaggagtgccccgacggcacgtattccgacgaggccaaccac
gtggacccgtgcctgccctgcaccgtgtgcgaggacaccgagcgccagctccgcgagtgc
acacgctgggccgacgccgagtgcgaggagatccctggccgttggattacacggtccaca
cccccagagggctcggacagcacagcccccagcacccaggagcctgaggcacctccagaa
caagacctcatagccagcacggtggcaggtgtggtgaccacagtgatgggcagctcccag
cccgtggtgacccgaggcaccaccgacaacctcatccctgtctattgctccatcctggct
gctgtggttgtgggccttgtggcctacatagccttcaagaggtggaacagctgcaagcag
aacaagcaaggagccaacagccggccagtgaaccagacgcccccaccagagggagaaaaa
ctccacagcgacagtggcatctccgtggacagccagagcctgcatgaccagcagccccac
acgcagacagcctcgggccaggccctcaagggtgacggaggcctctacagcagcctgccc
ccagccaagcgggaggaggtggagaagcttctcaacggctctgcgggggacacctggcgg
cacctggcgggcgagctgggctaccagcccgagcacatagactcctttacccatgaggcc
tgccccgttcgcgccctgcttgcaagctgggccacccaggacagcgccacactggacgcc
ctcctggccgccctgcgccgcatccagcgagccgacctcgtggagagtctgtgcagtgag
tccactgccacatccccggtgtga
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