KEGG   NETWORK: N01599
Entry
N01599                      Network                                
Name
Regulation of GF-RTK-RAS-ERK signaling, ubiquitination of RTK by CBL
Definition
CBL -| RTK
  Expanded
867 -| (1956,2064,2065,2066,2260,2263,2261,2264,4804,4914,4915,3643,3480,5156,5159,1436,3815,2322,2321,2324,3791,4233,7010,1969)
Class
nt06526 MAPK signaling
Type
Reference
Gene
867  CBL; Cbl proto-oncogene
1956  EGFR; epidermal growth factor receptor
2064  ERBB2; erb-b2 receptor tyrosine kinase 2
2065  ERBB3; erb-b2 receptor tyrosine kinase 3
2066  ERBB4; erb-b2 receptor tyrosine kinase 4
2260  FGFR1; fibroblast growth factor receptor 1
2263  FGFR2; fibroblast growth factor receptor 2
2261  FGFR3; fibroblast growth factor receptor 3
2264  FGFR4; fibroblast growth factor receptor 4
4804  NGFR; nerve growth factor receptor
4914  NTRK1; neurotrophic receptor tyrosine kinase 1
4915  NTRK2; neurotrophic receptor tyrosine kinase 2
3643  INSR; insulin receptor
3480  IGF1R; insulin like growth factor 1 receptor
5156  PDGFRA; platelet derived growth factor receptor alpha
5159  PDGFRB; platelet derived growth factor receptor beta
1436  CSF1R; colony stimulating factor 1 receptor
3815  KIT; KIT proto-oncogene, receptor tyrosine kinase
2322  FLT3; fms related receptor tyrosine kinase 3
2321  FLT1; fms related receptor tyrosine kinase 1
2324  FLT4; fms related receptor tyrosine kinase 4
3791  KDR; kinase insert domain receptor
4233  MET; MET proto-oncogene, receptor tyrosine kinase
7010  TEK; TEK receptor tyrosine kinase
1969  EPHA2; EPH receptor A2
Reference
PMID:34103645
  Authors
Pudewell S, Wittich C, Kazemein Jasemi NS, Bazgir F, Ahmadian MR
  Title
Accessory proteins of the RAS-MAPK pathway: moving from the side line to the front line.
  Journal
Commun Biol 4:696 (2021)
DOI:10.1038/s42003-021-02149-3
Reference
PMID:36394128
  Authors
Tartaglia M, Aoki Y, Gelb BD
  Title
The molecular genetics of RASopathies: An update on novel disease genes and new disorders.
  Journal
Am J Med Genet C Semin Med Genet 190:425-439 (2022)
DOI:10.1002/ajmg.c.32012
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