Miniopterus natalensis (Natal long-fingered bat): 107526004 Help Entry 107526004         CDS       T05883                                  Symbol ADCY1 Name (RefSeq) adenylate cyclase type 1   KO K08041   adenylate cyclase 1 [EC:4.6.1.1] Organism mna  Miniopterus natalensis (Natal long-fingered bat) Pathway mna00230   Purine metabolism mna01100   Metabolic pathways mna01522   Endocrine resistance mna04015   Rap1 signaling pathway mna04020   Calcium signaling pathway mna04022   cGMP-PKG signaling pathway mna04024   cAMP signaling pathway mna04062   Chemokine signaling pathway mna04072   Phospholipase D signaling pathway mna04081   Hormone signaling mna04082   Neuroactive ligand signaling mna04114   Oocyte meiosis mna04211   Longevity regulating pathway mna04213   Longevity regulating pathway - multiple species mna04261   Adrenergic signaling in cardiomyocytes mna04270   Vascular smooth muscle contraction mna04371   Apelin signaling pathway mna04540   Gap junction mna04611   Platelet activation mna04713   Circadian entrainment mna04714   Thermogenesis mna04720   Long-term potentiation mna04723   Retrograde endocannabinoid signaling mna04724   Glutamatergic synapse mna04725   Cholinergic synapse mna04727   GABAergic synapse mna04750   Inflammatory mediator regulation of TRP channels mna04911   Insulin secretion mna04912   GnRH signaling pathway mna04913   Ovarian steroidogenesis mna04914   Progesterone-mediated oocyte maturation mna04915   Estrogen signaling pathway mna04916   Melanogenesis mna04918   Thyroid hormone synthesis mna04921   Oxytocin signaling pathway mna04923   Regulation of lipolysis in adipocytes mna04925   Aldosterone synthesis and secretion mna04926   Relaxin signaling pathway mna04927   Cortisol synthesis and secretion mna04928   Parathyroid hormone synthesis, secretion and action mna04934   Cushing syndrome mna04935   Growth hormone synthesis, secretion and action mna04970   Salivary secretion mna04971   Gastric acid secretion mna04972   Pancreatic secretion mna04976   Bile secretion mna05032   Morphine addiction mna05142   Chagas disease mna05146   Amoebiasis mna05163   Human cytomegalovirus infection mna05166   Human T-cell leukemia virus 1 infection mna05200   Pathways in cancer mna05207   Chemical carcinogenesis - receptor activation mna05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:mna00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     107526004 (ADCY1)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     107526004 (ADCY1)    04371 Apelin signaling pathway     107526004 (ADCY1)    04020 Calcium signaling pathway     107526004 (ADCY1)    04072 Phospholipase D signaling pathway     107526004 (ADCY1)    04024 cAMP signaling pathway     107526004 (ADCY1)    04022 cGMP-PKG signaling pathway     107526004 (ADCY1)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     107526004 (ADCY1)    04081 Hormone signaling     107526004 (ADCY1)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     107526004 (ADCY1)   09144 Cellular community - eukaryotes    04540 Gap junction     107526004 (ADCY1)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     107526004 (ADCY1)    04062 Chemokine signaling pathway     107526004 (ADCY1)   09152 Endocrine system    04911 Insulin secretion     107526004 (ADCY1)    04923 Regulation of lipolysis in adipocytes     107526004 (ADCY1)    04912 GnRH signaling pathway     107526004 (ADCY1)    04913 Ovarian steroidogenesis     107526004 (ADCY1)    04915 Estrogen signaling pathway     107526004 (ADCY1)    04914 Progesterone-mediated oocyte maturation     107526004 (ADCY1)    04921 Oxytocin signaling pathway     107526004 (ADCY1)    04926 Relaxin signaling pathway     107526004 (ADCY1)    04935 Growth hormone synthesis, secretion and action     107526004 (ADCY1)    04918 Thyroid hormone synthesis     107526004 (ADCY1)    04928 Parathyroid hormone synthesis, secretion and action     107526004 (ADCY1)    04916 Melanogenesis     107526004 (ADCY1)    04925 Aldosterone synthesis and secretion     107526004 (ADCY1)    04927 Cortisol synthesis and secretion     107526004 (ADCY1)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     107526004 (ADCY1)    04270 Vascular smooth muscle contraction     107526004 (ADCY1)   09154 Digestive system    04970 Salivary secretion     107526004 (ADCY1)    04971 Gastric acid secretion     107526004 (ADCY1)    04972 Pancreatic secretion     107526004 (ADCY1)    04976 Bile secretion     107526004 (ADCY1)   09156 Nervous system    04724 Glutamatergic synapse     107526004 (ADCY1)    04727 GABAergic synapse     107526004 (ADCY1)    04725 Cholinergic synapse     107526004 (ADCY1)    04720 Long-term potentiation     107526004 (ADCY1)    04723 Retrograde endocannabinoid signaling     107526004 (ADCY1)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     107526004 (ADCY1)   09149 Aging    04211 Longevity regulating pathway     107526004 (ADCY1)    04213 Longevity regulating pathway - multiple species     107526004 (ADCY1)   09159 Environmental adaptation    04713 Circadian entrainment     107526004 (ADCY1)    04714 Thermogenesis     107526004 (ADCY1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     107526004 (ADCY1)    05207 Chemical carcinogenesis - receptor activation     107526004 (ADCY1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     107526004 (ADCY1)    05163 Human cytomegalovirus infection     107526004 (ADCY1)   09174 Infectious disease: parasitic    05146 Amoebiasis     107526004 (ADCY1)    05142 Chagas disease     107526004 (ADCY1)   09165 Substance dependence    05032 Morphine addiction     107526004 (ADCY1)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     107526004 (ADCY1)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     107526004 (ADCY1)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     107526004 (ADCY1) Enzymes [BR:mna01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      107526004 (ADCY1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N Adcy_cons_dom HNOBA Phage_holin_3_6 Motif Other DBs NCBI-GeneID:  107526004 NCBI-ProteinID:  XP_016053785 LinkDB All DBs Position Unknown AA seq 947 aa AA seqDB search MYGVFVRVLAERSQRRAFLQARTCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLK PPERIFHKIYIQRHDNENHCRRIKILGDCYYCVSGLTQPKTDHAHCCVEMGLDMIDTITS VAEATEVDLNMRVGLHTGRVLCGVLGLRKWQYDVWSNDVTLANVMETAGLPGKVHITKTT LTCLNGDYEVEPGHGQERNSFLRAHNIETFFIVPSHRRKIFPGLILSDIKPAKRMKFKTV CYLLVQLMQCRKMFKAEIPFSSVMTCQDDKRRALRTASEKLRNRLSFSTNVVYTTPGTRV NRYIGRLLEARQTELELADLNFVTLKYKQAERERKYHQLQDEHFTSAVGLALVLAALFGL VYLLIIPQSVALLLLLVFCICFLVACVLYLHVTRVQCLPGCLTIQIRTILCIFIVVLIYS VAQGCVVGCLPWAWSSSPNGSLVVLSPGGQSPVPPAPPCESAPHALLCGLVGTLPLAIFL RVSSLPKMILLCVLSTSYILVLELSGYTKAAGADAASRRSFEPIVAILLFSCTLALHARQ VDVKLRLDYLWAAQAEEERADMERVKLDNRRILFNLLPAHVAQHFLLSNPRNMTLPGPGA EETPCSFQTRSPAQRWLLASIVTVTCLRRNVTFNSSVFPTKLMDKDFYKDLEKIKTIGST YMAAVGLAPTAGAKARKSISSHLSTLADFAIEMFDVLDEINYQSYNDFVLRVGINVGPVV AGVIGARRPQYDIWGNTVNVASRMDSTGVPGRIQVTEEVQRLLRPGGYHFLCRGKVSVKG KGEMLTYFLEGRANGTGSHPRSLNSERKMCPYRRAGLQARLATGHPPVSPMAGLPGRTSV HRASAQPQWLVRATAPHPEVPPELRLSRRQFRTRLLPGTQEPQPYVPWAQTTARTSRCFH GPPASLARAPASSPCGVHAPADPATWTYCVHVSKATGASRYLVNRKQ NT seq 2844 nt NT seq  +upstreamnt  +downstreamnt atgtacggcgtgttcgtgagggtcctggccgagcgctcccagcggagggccttcctgcag gcgcggacctgcatcgaggaccggctgcggctcgaggacgaaaatgagaagcaggagcgg ctgctcatgagcctcctgccccggaacgtggccatggagatgaaggaggacttcctgaag cccccagagaggatcttccacaagatttacatccagcggcatgacaacgagaaccactgc cgtcgcatcaagatcctgggggactgttactactgcgtgtccggcctcacccagcccaag accgaccacgcccactgctgcgtggagatgggcctggacatgatcgacaccatcacgtct gtggccgaggccaccgaggtcgacctgaacatgcgcgtggggctgcacaccgggagggtc ctctgtggcgtcctgggcctgcgcaagtggcaatatgacgtctggtccaacgatgtgacc ctggccaacgtcatggagactgcaggcctgcccgggaaggtccacatcaccaagacgacc ctgacgtgcctgaacggcgactacgaggtggagcccggccacgggcaggagaggaacagc ttcctgagagctcacaacatcgagactttcttcattgtgccttcccaccggcgcaagatc ttcccggggctgatcctctcggacatcaagccggccaaacggatgaagttcaagacggtg tgctacctgctggtgcagctcatgcagtgccgcaagatgttcaaggcggagatccccttc tccagcgtcatgacctgccaggacgacaagcgcagggcgctgagaacagcctccgaaaaa ctcagaaaccgcttgtctttctcgaccaacgtcgtctacaccaccccaggcacccgcgtc aaccggtacatcggccgcctcctggaagcccggcagacggagctggagctggcggacctg aacttcgtcaccctcaagtacaagcaggccgagcgggagcggaagtaccaccagctgcag gacgaacacttcaccagcgccgtggggctcgccctggtcctggccgccctgttcggcctc gtctacctgctgataatcccgcagagcgtggctctcctgctcctgctggtgttttgcatc tgtttcctggtggcctgtgtcctgtacctgcatgtcacacgggtccagtgtctcccgggc tgcctgaccatccagattcgcaccatcctgtgcattttcatcgtggtcttgatctactcc gtggcccaaggatgtgtggtgggctgcctgccctgggcctggagctccagccccaacggg tccctggtggtgctgtcgcccggaggccagagcccggtgccgcccgccccgccctgcgag tccgcgccccacgccctgctctgcggcctcgtgggcaccctccccctggccatcttcctg cgggtctcctccttgcccaaaatgatcctgctgtgcgtgctcagcacgtcctacatcctg gtcctggagctcagcgggtacaccaaggccgcgggggccgacgccgcctccaggcgcagc ttcgagccgatcgtggcgatcctgctgttctcgtgcacgctggccctgcacgcccggcag gtggacgtcaagctgcggctggactacctctgggccgcgcaggccgaggaggagcgtgcc gacatggagagagtgaagctggacaacaggaggatcctcttcaacctgctcccggcccac gtggcccagcacttcctcctgtccaacccccggaacatgaccttgcctggtcccggagca gaggagacaccgtgctccttccagacgcgctcgccggctcagcgctggctcctggcgtcg atcgtcacggtgacttgtctaagacgtaatgtaacgtttaacagttctgtgtttccaaca aagctcatggacaaagacttttacaaggacctggagaagatcaagaccatcgggagcacc tacatggcggccgtggggctggcgcccacggccggggccaaggcgaggaagtccatctcc tcccacctcagcaccctggcggactttgccatcgagatgtttgacgtcctggacgagatc aactaccagtcctacaatgacttcgtgctccgcgtgggcataaacgttggccccgtggtg gccggggtgatcggggctcgccggccgcagtacgacatttgggggaacacggtcaacgtg gccagtcggatggacagcactggggttccgggcagaatccaggtgaccgaggaggtgcag cggctgctgaggccgggcgggtaccacttcctgtgccggggcaaggtcagcgtcaagggc aagggcgagatgctgacctacttcctggaaggcagggccaacggaactggctcgcacccc aggtccctgaactcggagcggaaaatgtgtccttacaggagggctggcctccaggccaga ctggccacgggccaccccccggtttcccccatggccggcctcccgggcaggacctctgtc cacagagccagtgcccagccgcagtggttggttcgggcgactgctccgcaccccgaggtc cccccggagctgcgcctcagccgccggcagttccgaacgcgcctgctccccgggacccag gagccgcagccatatgtcccctgggcgcagaccacagcccgaacttccagatgcttccac gggccaccagcctcgctggcccgcgccccggcgtcttcaccctgcggggtacacgcccct gcagacccagccacctggacctactgtgtccatgtctccaaagccaccggggcttccaga tacctggtgaaccggaagcaataa

Miniopterus natalensis (Natal long-fingered bat): 107527242 Help Entry 107527242         CDS       T05883                                  Symbol ADCY5 Name (RefSeq) adenylate cyclase type 5 isoform X1   KO K08045   adenylate cyclase 5 [EC:4.6.1.1] Organism mna  Miniopterus natalensis (Natal long-fingered bat) Pathway mna00230   Purine metabolism mna01100   Metabolic pathways mna01522   Endocrine resistance mna04015   Rap1 signaling pathway mna04022   cGMP-PKG signaling pathway mna04024   cAMP signaling pathway mna04062   Chemokine signaling pathway mna04072   Phospholipase D signaling pathway mna04081   Hormone signaling mna04082   Neuroactive ligand signaling mna04114   Oocyte meiosis mna04211   Longevity regulating pathway mna04213   Longevity regulating pathway - multiple species mna04261   Adrenergic signaling in cardiomyocytes mna04270   Vascular smooth muscle contraction mna04371   Apelin signaling pathway mna04540   Gap junction mna04611   Platelet activation mna04713   Circadian entrainment mna04714   Thermogenesis mna04723   Retrograde endocannabinoid signaling mna04724   Glutamatergic synapse mna04725   Cholinergic synapse mna04726   Serotonergic synapse mna04727   GABAergic synapse mna04728   Dopaminergic synapse mna04750   Inflammatory mediator regulation of TRP channels mna04911   Insulin secretion mna04912   GnRH signaling pathway mna04913   Ovarian steroidogenesis mna04914   Progesterone-mediated oocyte maturation mna04915   Estrogen signaling pathway mna04916   Melanogenesis mna04918   Thyroid hormone synthesis mna04921   Oxytocin signaling pathway mna04923   Regulation of lipolysis in adipocytes mna04924   Renin secretion mna04925   Aldosterone synthesis and secretion mna04926   Relaxin signaling pathway mna04927   Cortisol synthesis and secretion mna04928   Parathyroid hormone synthesis, secretion and action mna04934   Cushing syndrome mna04935   Growth hormone synthesis, secretion and action mna04970   Salivary secretion mna04971   Gastric acid secretion mna04972   Pancreatic secretion mna04976   Bile secretion mna05012   Parkinson disease mna05030   Cocaine addiction mna05031   Amphetamine addiction mna05032   Morphine addiction mna05034   Alcoholism mna05163   Human cytomegalovirus infection mna05166   Human T-cell leukemia virus 1 infection mna05200   Pathways in cancer mna05207   Chemical carcinogenesis - receptor activation mna05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:mna00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     107527242 (ADCY5)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     107527242 (ADCY5)    04371 Apelin signaling pathway     107527242 (ADCY5)    04072 Phospholipase D signaling pathway     107527242 (ADCY5)    04024 cAMP signaling pathway     107527242 (ADCY5)    04022 cGMP-PKG signaling pathway     107527242 (ADCY5)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     107527242 (ADCY5)    04081 Hormone signaling     107527242 (ADCY5)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     107527242 (ADCY5)   09144 Cellular community - eukaryotes    04540 Gap junction     107527242 (ADCY5)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     107527242 (ADCY5)    04062 Chemokine signaling pathway     107527242 (ADCY5)   09152 Endocrine system    04911 Insulin secretion     107527242 (ADCY5)    04923 Regulation of lipolysis in adipocytes     107527242 (ADCY5)    04912 GnRH signaling pathway     107527242 (ADCY5)    04913 Ovarian steroidogenesis     107527242 (ADCY5)    04915 Estrogen signaling pathway     107527242 (ADCY5)    04914 Progesterone-mediated oocyte maturation     107527242 (ADCY5)    04921 Oxytocin signaling pathway     107527242 (ADCY5)    04926 Relaxin signaling pathway     107527242 (ADCY5)    04935 Growth hormone synthesis, secretion and action     107527242 (ADCY5)    04918 Thyroid hormone synthesis     107527242 (ADCY5)    04928 Parathyroid hormone synthesis, secretion and action     107527242 (ADCY5)    04916 Melanogenesis     107527242 (ADCY5)    04924 Renin secretion     107527242 (ADCY5)    04925 Aldosterone synthesis and secretion     107527242 (ADCY5)    04927 Cortisol synthesis and secretion     107527242 (ADCY5)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     107527242 (ADCY5)    04270 Vascular smooth muscle contraction     107527242 (ADCY5)   09154 Digestive system    04970 Salivary secretion     107527242 (ADCY5)    04971 Gastric acid secretion     107527242 (ADCY5)    04972 Pancreatic secretion     107527242 (ADCY5)    04976 Bile secretion     107527242 (ADCY5)   09156 Nervous system    04724 Glutamatergic synapse     107527242 (ADCY5)    04727 GABAergic synapse     107527242 (ADCY5)    04725 Cholinergic synapse     107527242 (ADCY5)    04728 Dopaminergic synapse     107527242 (ADCY5)    04726 Serotonergic synapse     107527242 (ADCY5)    04723 Retrograde endocannabinoid signaling     107527242 (ADCY5)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     107527242 (ADCY5)   09149 Aging    04211 Longevity regulating pathway     107527242 (ADCY5)    04213 Longevity regulating pathway - multiple species     107527242 (ADCY5)   09159 Environmental adaptation    04713 Circadian entrainment     107527242 (ADCY5)    04714 Thermogenesis     107527242 (ADCY5)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     107527242 (ADCY5)    05207 Chemical carcinogenesis - receptor activation     107527242 (ADCY5)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     107527242 (ADCY5)    05163 Human cytomegalovirus infection     107527242 (ADCY5)   09164 Neurodegenerative disease    05012 Parkinson disease     107527242 (ADCY5)   09165 Substance dependence    05030 Cocaine addiction     107527242 (ADCY5)    05031 Amphetamine addiction     107527242 (ADCY5)    05032 Morphine addiction     107527242 (ADCY5)    05034 Alcoholism     107527242 (ADCY5)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     107527242 (ADCY5)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     107527242 (ADCY5)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     107527242 (ADCY5) Enzymes [BR:mna01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      107527242 (ADCY5) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  AC_N Guanylate_cyc Adcy_cons_dom TBK1_ULD GBR2_CC Motif Other DBs NCBI-GeneID:  107527242 NCBI-ProteinID:  XP_016055424 LinkDB All DBs Position Unknown AA seq 1040 aa AA seqDB search MLMAVLVLVCLVMLAFHAARPPLQLPYLSVLAAAVGVILVMAVLCNRAAFHQDHMGLACY ALIAVVLAVQVVGLLLPQPRSASEGIWWTVFFIYTIYTLLPVRMRAAVLSGVLLSAIHLG IALHTNAQDQFLLKQLVSNVLIFSCTNIVGICTHYPAEVSQRQAFQETRECIQARLHSQR ENQQQERLLLSVLPRHVAMEMKADINAKQEDMMFHKIYIQKHDNVSILFADIEGFTSLAS QCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVEMGMD MIEAISLPPTLCAWPVILSQPHPCSIPRLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQ FDVWSNDVTLANHMEAGGKAGRIHITKATLNYLNGDYEVEPGCGGERNAYLKEHSIETFL ILRCTQKRKDEKAMIAKMNRQRTNSIGHNPPHWGAERPFYNHLGGNQVSKEMKRMGFEDP KDKNAQESANPEDEVDEFLGRAIDARSIDRLRSEHVRKFLLTFREPDLEKKYSKQVDDRF GAYVACASLVFLFICFVQITIVPHSVFMLSFYLTCFVLLTLVVFVSVVYSCVKLFPGPLQ TLSRKIVRSKMNSTLVGVFTIILVFLSAFVNMFMCNSEDLFGCLAEEHNVSTSQVNACHV VESAVNYSLGDEQGFCSSTWPNCNFPEYFTYSVLLSLLACSVFLQISCIGKLVLMLSIEL IYVLIVEVPGVTLFDNADLLVTANAIDFNNNGTSQCPEHATKVALKVVTPIIISVFVLAL YLHAQQVESTARLDFLWKLQATEEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDE LYYQSCECVAVMFASIANFSEFYVELEANNEGVECLRLLNEIIADFDEIISEDRFKQLEK IKTIGSTYMAASGLNDSTYDKAGKTHIKALADFAMKLMDQMKYINEHSFNNFQMKIGLNI GPVVAGVIGARKPQYDIWGNTVNVASRMDSTGVPDRIQVTTDMYQVLAANTYQLECRGVV KVKGKGEMMTYFLNGGPPLS NT seq 3123 nt NT seq  +upstreamnt  +downstreamnt atgctgatggccgtgctggtgctcgtgtgcctcgtcatgttggccttccacgcggcgcgg ccaccgctccagttgccctacctttccgtgctggcggccgccgtgggcgtgatcctcgtg atggccgtgctctgcaaccgcgccgccttccaccaggaccacatgggcctggcctgctat gcgcttattgcggtggtgctggccgtccaggtggtgggcctgctgctgccccagccgcgc agcgcctcggagggcatctggtggaccgtgttcttcatctacaccatctatacgctgctg ccggtgcgcatgagggccgcggtactcagcggggtgctcctgtctgctatccacttgggg attgccctgcacaccaacgcccaggaccagttcctgctcaagcagcttgtctccaatgtc ctcattttctcttgcaccaacatcgtgggcatctgcacccactatccagctgaggtctcc cagagacaggctttccaggagaccagggagtgcatccaggcgcggctccactctcagcgg gagaaccaacaacaggagcggctcctgctgtctgtccttccccgtcatgttgccatggag atgaaagcagacatcaacgccaagcaggaggatatgatgttccataagatttacatccag aaacatgacaacgtgagcatcctgtttgctgacatcgagggctttaccagcctggcgtcg cagtgcactgcccaggagctggtcatgactctcaacgagctctttgcccgcttcgacaag ttggctgcggagaatcactgtttacgtattaagatcctgggggattgttattactgcgtc tcggggctgcctgaagcgagggctgaccacgcccactgctgtgtggagatgggcatggac atgattgaagccatctccctccctcccactctgtgtgcctggcctgtgatcctctcccag cctcatccctgctccatccccaggttggtccgggaggtgacaggggtgaacgtgaacatg cgcgtgggaattcacagcgggcgagtacactgcggtgtccttggtctcaggaagtggcag ttcgacgtctggtctaacgacgtcacactggccaaccacatggaggctggaggcaaggct ggacgcatccacatcaccaaggccacactcaactacctgaacggggactacgaggtggag ccaggctgtgggggcgagcgcaacgcctacctcaaggagcacagcatcgagaccttcctc atcctgcgctgcacccagaagcggaaagacgagaaggccatgatcgccaagatgaatcgc cagaggaccaactccattgggcacaacccgccccattggggggccgagcgccccttctac aaccacctgggcggcaaccaggtgtccaaggagatgaagcggatgggcttcgaagacccc aaggacaagaatgcccaagaaagtgcaaaccccgaggatgaagtggatgaatttctgggc cgcgccattgacgccaggagcattgacaggctgcggtctgagcatgttcgcaagttcctc ttgaccttcagggagcctgacttagagaagaagtactccaagcaggtggatgaccgattc ggtgcctacgtggcgtgtgcctcgctcgtcttcctcttcatctgcttcgtccagatcacc atcgtgccccactccgtgttcatgttgagtttctacctgacctgttttgtgctgctgacc ttggtggtgtttgtgtccgtggtctactcctgcgtgaagctcttcccaggccccctgcag accctctccaggaagatcgtgcggtccaagatgaatagcaccctggttggcgtgttcacc atcatcctggtgttcctgtcggcttttgtcaacatgttcatgtgcaactccgaggacctg ttcggctgcctggcagaggaacataacgtcagcaccagccaggtcaacgcgtgccacgtg gtggagtccgctgtcaactacagcctgggggatgagcagggcttctgcagcagcacctgg cccaactgcaacttccccgagtacttcacctacagcgtgctgctcagcctgctggcctgc tccgtgttcctgcaaatcagctgcattgggaagctggtgctcatgctgtccattgagctt atatatgtgctcatcgtggaggtgcccggtgtgacgctctttgacaatgccgaccttctg gtcactgccaatgccatagacttcaacaacaacgggacctcccagtgccctgagcatgcg accaaggtggcgctgaaggtggtgacgcccatcatcatctcagtctttgtgctggccctg tacctgcacgcccagcaggtggagtccaccgcccgcctcgacttcctctggaaactgcag gccacagaggagaaggaggagatggaggagctgcaggcctacaaccggcggctgctgcac aacatcctgcccaaggacgtggccgcccacttcctggcccgcgagcggcgcaatgacgag ctctactaccagtcctgcgagtgcgtggccgtcatgttcgcctccatcgccaacttctcc gagttctatgtggagctggaggccaacaacgagggtgtcgagtgccttcggctgctcaac gagatcatcgccgactttgatgagatcatcagcgaggatcggtttaagcagctggaaaag atcaagaccatcggcagcacctacatggctgcctcaggccttaatgattccacctacgac aaggcaggcaagacccacatcaaagctctggccgacttcgccatgaagctgatggaccaa atgaagtacatcaacgagcactccttcaacaacttccagatgaagattgggctcaatatc ggccccgtggtggccggggtgatcggggcccgcaagcctcagtacgacatctggggcaac acggtgaacgtggccagccgcatggacagcaccggcgtgcctgaccgcatccaggtcaca acagacatgtaccaggtgctggctgccaacacataccagctggagtgccgaggtgtggtc aaggtcaagggcaaaggcgagatgatgacctatttcctcaatggagggcccccgctcagt tag

Miniopterus natalensis (Natal long-fingered bat): 107528232 Help Entry 107528232         CDS       T05883                                  Symbol ADCY6 Name (RefSeq) adenylate cyclase type 6 isoform X1   KO K08046   adenylate cyclase 6 [EC:4.6.1.1] Organism mna  Miniopterus natalensis (Natal long-fingered bat) Pathway mna00230   Purine metabolism mna01100   Metabolic pathways mna01522   Endocrine resistance mna04015   Rap1 signaling pathway mna04022   cGMP-PKG signaling pathway mna04024   cAMP signaling pathway mna04062   Chemokine signaling pathway mna04072   Phospholipase D signaling pathway mna04081   Hormone signaling mna04082   Neuroactive ligand signaling mna04114   Oocyte meiosis mna04211   Longevity regulating pathway mna04213   Longevity regulating pathway - multiple species mna04261   Adrenergic signaling in cardiomyocytes mna04270   Vascular smooth muscle contraction mna04371   Apelin signaling pathway mna04540   Gap junction mna04611   Platelet activation mna04713   Circadian entrainment mna04714   Thermogenesis mna04723   Retrograde endocannabinoid signaling mna04724   Glutamatergic synapse mna04725   Cholinergic synapse mna04727   GABAergic synapse mna04742   Taste transduction mna04750   Inflammatory mediator regulation of TRP channels mna04911   Insulin secretion mna04912   GnRH signaling pathway mna04913   Ovarian steroidogenesis mna04914   Progesterone-mediated oocyte maturation mna04915   Estrogen signaling pathway mna04916   Melanogenesis mna04918   Thyroid hormone synthesis mna04921   Oxytocin signaling pathway mna04923   Regulation of lipolysis in adipocytes mna04924   Renin secretion mna04925   Aldosterone synthesis and secretion mna04926   Relaxin signaling pathway mna04927   Cortisol synthesis and secretion mna04928   Parathyroid hormone synthesis, secretion and action mna04934   Cushing syndrome mna04935   Growth hormone synthesis, secretion and action mna04961   Endocrine and other factor-regulated calcium reabsorption mna04962   Vasopressin-regulated water reabsorption mna04970   Salivary secretion mna04971   Gastric acid secretion mna04972   Pancreatic secretion mna04976   Bile secretion mna05032   Morphine addiction mna05163   Human cytomegalovirus infection mna05166   Human T-cell leukemia virus 1 infection mna05200   Pathways in cancer mna05207   Chemical carcinogenesis - receptor activation mna05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:mna00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     107528232 (ADCY6)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     107528232 (ADCY6)    04371 Apelin signaling pathway     107528232 (ADCY6)    04072 Phospholipase D signaling pathway     107528232 (ADCY6)    04024 cAMP signaling pathway     107528232 (ADCY6)    04022 cGMP-PKG signaling pathway     107528232 (ADCY6)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     107528232 (ADCY6)    04081 Hormone signaling     107528232 (ADCY6)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     107528232 (ADCY6)   09144 Cellular community - eukaryotes    04540 Gap junction     107528232 (ADCY6)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     107528232 (ADCY6)    04062 Chemokine signaling pathway     107528232 (ADCY6)   09152 Endocrine system    04911 Insulin secretion     107528232 (ADCY6)    04923 Regulation of lipolysis in adipocytes     107528232 (ADCY6)    04912 GnRH signaling pathway     107528232 (ADCY6)    04913 Ovarian steroidogenesis     107528232 (ADCY6)    04915 Estrogen signaling pathway     107528232 (ADCY6)    04914 Progesterone-mediated oocyte maturation     107528232 (ADCY6)    04921 Oxytocin signaling pathway     107528232 (ADCY6)    04926 Relaxin signaling pathway     107528232 (ADCY6)    04935 Growth hormone synthesis, secretion and action     107528232 (ADCY6)    04918 Thyroid hormone synthesis     107528232 (ADCY6)    04928 Parathyroid hormone synthesis, secretion and action     107528232 (ADCY6)    04916 Melanogenesis     107528232 (ADCY6)    04924 Renin secretion     107528232 (ADCY6)    04925 Aldosterone synthesis and secretion     107528232 (ADCY6)    04927 Cortisol synthesis and secretion     107528232 (ADCY6)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     107528232 (ADCY6)    04270 Vascular smooth muscle contraction     107528232 (ADCY6)   09154 Digestive system    04970 Salivary secretion     107528232 (ADCY6)    04971 Gastric acid secretion     107528232 (ADCY6)    04972 Pancreatic secretion     107528232 (ADCY6)    04976 Bile secretion     107528232 (ADCY6)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     107528232 (ADCY6)    04961 Endocrine and other factor-regulated calcium reabsorption     107528232 (ADCY6)   09156 Nervous system    04724 Glutamatergic synapse     107528232 (ADCY6)    04727 GABAergic synapse     107528232 (ADCY6)    04725 Cholinergic synapse     107528232 (ADCY6)    04723 Retrograde endocannabinoid signaling     107528232 (ADCY6)   09157 Sensory system    04742 Taste transduction     107528232 (ADCY6)    04750 Inflammatory mediator regulation of TRP channels     107528232 (ADCY6)   09149 Aging    04211 Longevity regulating pathway     107528232 (ADCY6)    04213 Longevity regulating pathway - multiple species     107528232 (ADCY6)   09159 Environmental adaptation    04713 Circadian entrainment     107528232 (ADCY6)    04714 Thermogenesis     107528232 (ADCY6)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     107528232 (ADCY6)    05207 Chemical carcinogenesis - receptor activation     107528232 (ADCY6)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     107528232 (ADCY6)    05163 Human cytomegalovirus infection     107528232 (ADCY6)   09165 Substance dependence    05032 Morphine addiction     107528232 (ADCY6)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     107528232 (ADCY6)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     107528232 (ADCY6)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     107528232 (ADCY6) Enzymes [BR:mna01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      107528232 (ADCY6) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N Adcy_cons_dom HNOBA TBK1_ULD GBR2_CC Motif Other DBs NCBI-GeneID:  107528232 NCBI-ProteinID:  XP_016056698 LinkDB All DBs Position Unknown AA seq 1166 aa AA seqDB search MSWFSGLLVPKVDERKTAWGERNGQKRPRHRTRTSGFCAPRYMSCLQDAQPPSPSPTAPP RCPWQEEAFIRRGGPGKGTELGLRAVALGFEDTETTAAVGVAEVAPDVAPRNRRSCWRRL VQVFQSKQFRSAKLERLYQRYFFQMNQSSLTLLMAVLVLLTAVLLAFHAAPARPQPAYVA LLACAAILFVVLMVVCNRHSFRQDSMWVVSYVVLGILAAVQVGGALAANPHSPSVGLWCP VFFVYITYTLLPIRMRAAVFSGLGLSTLHMILAWQLNRGDAFLWKQLGANMLLFLCTNVI GICTHYPAEVSQRQAFQETRGYIQARLHLQHENRQQERLLLSVLPQHVAMEMKEDINTKK EDMMFHKIYIQKHDNVSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLAAENHCLR IKILGDCYYCVSGLPEARADHAHCCVEMGVDMIEAISLVREVTGVNVNMRVGIHSGRVHC GVLGLRKWQFDVWSNDVTLANHMEAGGRAGRIHITRATLQYLNGDYEVEPGHGGERNAYL KEQHIETFLILGTSQKRKEEKAMLAKLQRTRANSVEGLMPRWVPDRAFSRTKDSKAFRQM GIDDSSKDNRGAQDALNPEDEVDEFLGRAIDARSIDQLRKDHVRRFLLTFQREDLEKKYS QKVDPRFGAYVACALLVFCFICFIQLLVFPHSMLMFGIYAGIFLLLLITVLTCAVYSCGS LCPKALQRLSRSIVRSRAHSTAVGIFSVLLVFTSAIANMFTCNHTPIRTCAARMLNLTPA DITACHLQQLNYSLGLDAPLCEGTAPTCSFPEYFVGNMLLSLLASSVFLHINSIGKLAMI FVLGLIYLVLLLLGPPATIFDNYDLLLGVHGLASSNETFSGLDCPAAGRVALKYMTPVIL LVFALALYLHAQQVESTARLDFLWKLQATGEKEEMEELQAYNRRLLHNILPKDVAAHFLA RERRNDELYYQSCECVAVMFASIANFSEFYVELEANNEGVECLRLLNEIIADFDEIISEE RFRQLEKIKTIGSTYMAASGLNASTYDQVGRSHITALADYAMRLMEQMKHINEHSFNNFQ MKIGLNMGPVVAGVIGARKPQYDIWGNTVNVSSRMDSTGVPDRIQVTTDLYQVLAAKGYQ LECRGVVKVKGKGEMTTYFLNGGPSS NT seq 3501 nt NT seq  +upstreamnt  +downstreamnt atgtcatggtttagtggccttctggtccccaaagtggatgaacggaaaacagcctggggt gaacgcaatgggcagaagcgccctcgtcacaggactcgcaccagtggcttctgtgcgccc cgatatatgagctgcctccaggatgcacagccacccagccccagccctacagctccacct cggtgcccctggcaggaggaggccttcatccggaggggtggcccaggcaagggcactgag ctggggctgcgggcagtggccctgggctttgaggacactgagacaacagcagcggttggg gtggctgaggtggcacccgatgtagcacccaggaacaggcgatcctgctggcgccggctg gtgcaggtgttccagtcgaagcagttccgctcagccaagctggagcgcctgtaccagcgg tacttcttccagatgaaccagagcagcctcacgctgctgatggcggtgctcgtgctgctc acagctgtgctgctggccttccatgctgcgcccgcccgccctcagcctgcctacgtggcc ctgctggcctgtgcagccatcctcttcgtggtgctcatggtggtgtgcaaccggcatagt ttccgccaggactccatgtgggtggtgagctacgtggtgctgggcatcctggcagctgtg caggttgggggtgccctggcagccaacccccatagcccatcagtaggcctttggtgccct gtgttctttgtctacatcacctacacgctcctacccatccgcatgcgggcagctgtcttc agtggcctgggcctctccaccctacatatgatcttggcctggcaactcaaccgtggtgat gccttcctctggaagcagcttggtgccaacatgctgctgttcctctgtaccaacgttatt ggcatctgcacacactacccagctgaggtgtctcagcgccaggcctttcaagagactcgt ggctacatccaagcccggctgcacctgcagcatgagaatcggcagcaggagcggctactg ctgtcggtgttgccccagcacgttgccatggagatgaaagaagacatcaacacaaagaaa gaagacatgatgttccacaagatctacatccagaagcatgacaatgtcagcatcctgttt gcagacatcgaaggttttaccagcctggcatcccagtgcaccgcacaggagctggtcatg accctgaatgagctctttgcccggtttgacaagttggctgcggaaaatcactgcctgagg atcaagatcttaggggactgttactactgtgtgtcaggattgcctgaggcccgggcagac catgcccactgctgtgtggagatgggggtggacatgatcgaggccatctcgctggtgcgt gaggtgacaggtgtgaacgtgaacatgcgcgtgggcatccatagcgggcgcgtgcactgc ggtgtccttggcctgcggaaatggcaattcgatgtgtggtccaatgacgtgactctggcc aaccacatggaggcggggggccgggccggccgcatccacatcactcgggccacgctgcag tacctgaatggggactacgaggtggagcctggccatggtggtgagcgcaatgcatacctc aaggagcagcacattgagaccttcctcatcctgggcaccagccagaaacggaaagaggag aaggccatgctggccaagctgcagcggacgcgggccaactctgtggaagggctgatgcca cgctgggtgcctgaccgagccttctcccggaccaaggactccaaggctttccgccagatg ggcattgatgattccagcaaagacaaccggggtgcccaagatgccctgaaccctgaggat gaggtagatgagttcctgggccgtgccattgatgcccgtagcatcgatcagctgcgcaag gaccacgtgcgccggttcctgctcaccttccagagagaggatcttgaaaagaagtactca cagaaagtggatccccgtttcggagcctacgtggcctgtgccctgttggtcttctgcttc atctgcttcatccagcttctcgtcttcccacactcaatgctgatgtttgggatctatgcc gggatcttcctactgctgctgatcactgtgctgacttgcgcggtgtactcctgtggctct ctttgccctaaggccctgcaacgcctgtcgcgcagcattgtacgctcgcgggcacacagc actgcagttggcatcttttcggtcctgcttgtgttcacctccgccatcgccaacatgttc acctgtaaccacacccccatacggacctgtgcagcccggatgctgaatttaacacctgct gacatcaccgcctgccacctgcagcagctcaattattctctgggccttgatgctcccctg tgtgagggcaccgcacccacctgcagcttccctgagtactttgtcgggaacatgctgctg agtctgttggcgagctctgtcttcctgcacatcaatagcatcgggaagttggccatgatc tttgtcctggggctcatctatttggtgctgcttctactgggccccccagccactatcttt gacaactatgatctgctgcttggagtccatggcttggcttcttccaatgagaccttcagt gggctggactgcccagctgcagggagggtggcactcaaatacatgacccccgtgattctg ctggtgtttgcgctggcactgtatctgcatgctcagcaggtggaatcgactgcccgcctg gacttcctctggaaactgcaggcaacaggggagaaggaggagatggaggagctccaggca tacaaccggcgtctgctgcataacatcctgcccaaggatgtggccgcccactttctggcc cgggagcgccggaatgatgagctgtactatcagtcttgtgagtgtgtggctgtcatgttt gcctccattgccaacttctctgagttctacgtggagctggaggcaaacaatgagggtgtc gagtgccttcggctgctcaatgagatcatcgctgactttgatgagatcatcagtgaggag aggttccggcagctggagaagatcaagacgattggtagcacctacatggctgcctctggg ctgaacgccagcacctatgatcaggtgggccgctcccacatcactgccctcgctgactac gctatgcggctcatggagcagatgaagcacatcaatgagcactccttcaacaatttccag atgaagattggactgaacatgggccctgtggtggcaggcgtcattggggctcggaagcca cagtatgacatctgggggaatacagtgaatgtctctagccggatggacagcacaggggtt cctgaccgaatccaggtgaccacggacctgtaccaggttctagctgccaagggctaccag ctggagtgtcgaggggtggtcaaggtgaagggcaagggggagatgaccacctacttcctc aatgggggccccagcagttag

Miniopterus natalensis (Natal long-fingered bat): 107531029 Help Entry 107531029         CDS       T05883                                  Symbol ADCY7 Name (RefSeq) adenylate cyclase type 7   KO K08047   adenylate cyclase 7 [EC:4.6.1.1] Organism mna  Miniopterus natalensis (Natal long-fingered bat) Pathway mna00230   Purine metabolism mna01100   Metabolic pathways mna01522   Endocrine resistance mna04015   Rap1 signaling pathway mna04020   Calcium signaling pathway mna04022   cGMP-PKG signaling pathway mna04024   cAMP signaling pathway mna04062   Chemokine signaling pathway mna04072   Phospholipase D signaling pathway mna04081   Hormone signaling mna04082   Neuroactive ligand signaling mna04114   Oocyte meiosis mna04211   Longevity regulating pathway mna04213   Longevity regulating pathway - multiple species mna04261   Adrenergic signaling in cardiomyocytes mna04270   Vascular smooth muscle contraction mna04371   Apelin signaling pathway mna04540   Gap junction mna04611   Platelet activation mna04713   Circadian entrainment mna04714   Thermogenesis mna04723   Retrograde endocannabinoid signaling mna04724   Glutamatergic synapse mna04725   Cholinergic synapse mna04727   GABAergic synapse mna04750   Inflammatory mediator regulation of TRP channels mna04911   Insulin secretion mna04912   GnRH signaling pathway mna04913   Ovarian steroidogenesis mna04914   Progesterone-mediated oocyte maturation mna04915   Estrogen signaling pathway mna04916   Melanogenesis mna04918   Thyroid hormone synthesis mna04921   Oxytocin signaling pathway mna04923   Regulation of lipolysis in adipocytes mna04925   Aldosterone synthesis and secretion mna04926   Relaxin signaling pathway mna04927   Cortisol synthesis and secretion mna04928   Parathyroid hormone synthesis, secretion and action mna04934   Cushing syndrome mna04935   Growth hormone synthesis, secretion and action mna04970   Salivary secretion mna04971   Gastric acid secretion mna04972   Pancreatic secretion mna04976   Bile secretion mna05032   Morphine addiction mna05163   Human cytomegalovirus infection mna05166   Human T-cell leukemia virus 1 infection mna05200   Pathways in cancer mna05207   Chemical carcinogenesis - receptor activation mna05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:mna00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     107531029 (ADCY7)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     107531029 (ADCY7)    04371 Apelin signaling pathway     107531029 (ADCY7)    04020 Calcium signaling pathway     107531029 (ADCY7)    04072 Phospholipase D signaling pathway     107531029 (ADCY7)    04024 cAMP signaling pathway     107531029 (ADCY7)    04022 cGMP-PKG signaling pathway     107531029 (ADCY7)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     107531029 (ADCY7)    04081 Hormone signaling     107531029 (ADCY7)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     107531029 (ADCY7)   09144 Cellular community - eukaryotes    04540 Gap junction     107531029 (ADCY7)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     107531029 (ADCY7)    04062 Chemokine signaling pathway     107531029 (ADCY7)   09152 Endocrine system    04911 Insulin secretion     107531029 (ADCY7)    04923 Regulation of lipolysis in adipocytes     107531029 (ADCY7)    04912 GnRH signaling pathway     107531029 (ADCY7)    04913 Ovarian steroidogenesis     107531029 (ADCY7)    04915 Estrogen signaling pathway     107531029 (ADCY7)    04914 Progesterone-mediated oocyte maturation     107531029 (ADCY7)    04921 Oxytocin signaling pathway     107531029 (ADCY7)    04926 Relaxin signaling pathway     107531029 (ADCY7)    04935 Growth hormone synthesis, secretion and action     107531029 (ADCY7)    04918 Thyroid hormone synthesis     107531029 (ADCY7)    04928 Parathyroid hormone synthesis, secretion and action     107531029 (ADCY7)    04916 Melanogenesis     107531029 (ADCY7)    04925 Aldosterone synthesis and secretion     107531029 (ADCY7)    04927 Cortisol synthesis and secretion     107531029 (ADCY7)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     107531029 (ADCY7)    04270 Vascular smooth muscle contraction     107531029 (ADCY7)   09154 Digestive system    04970 Salivary secretion     107531029 (ADCY7)    04971 Gastric acid secretion     107531029 (ADCY7)    04972 Pancreatic secretion     107531029 (ADCY7)    04976 Bile secretion     107531029 (ADCY7)   09156 Nervous system    04724 Glutamatergic synapse     107531029 (ADCY7)    04727 GABAergic synapse     107531029 (ADCY7)    04725 Cholinergic synapse     107531029 (ADCY7)    04723 Retrograde endocannabinoid signaling     107531029 (ADCY7)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     107531029 (ADCY7)   09149 Aging    04211 Longevity regulating pathway     107531029 (ADCY7)    04213 Longevity regulating pathway - multiple species     107531029 (ADCY7)   09159 Environmental adaptation    04713 Circadian entrainment     107531029 (ADCY7)    04714 Thermogenesis     107531029 (ADCY7)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     107531029 (ADCY7)    05207 Chemical carcinogenesis - receptor activation     107531029 (ADCY7)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     107531029 (ADCY7)    05163 Human cytomegalovirus infection     107531029 (ADCY7)   09165 Substance dependence    05032 Morphine addiction     107531029 (ADCY7)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     107531029 (ADCY7)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     107531029 (ADCY7)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     107531029 (ADCY7) Enzymes [BR:mna01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      107531029 (ADCY7) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc Adcy_cons_dom AC_N Motif Other DBs NCBI-GeneID:  107531029 NCBI-ProteinID:  XP_016060493 LinkDB All DBs Position Unknown AA seq 1080 aa AA seqDB search MPAKGRYFLNEGEEGPDQNALYEKYRLTSQHGPLLLTLLLVAIVACIALIIIAFSDGDPS RQQALLGTAFSMLAVFMVLYVLVYVECLVRQWLRASALLIWVCLVILGYVLVFDSWMKAP CAWEQVPFFLFIVFVAYTLLPFSMQGAIVAGVVASASHLLVLGTLMGVFSSPSIWMGLQL LANAVIFLCGNLTGAFHKHQMQDASHDLFTYTVKCIQIRRKLRIEKRQQENLLLSVLPAH ISMGMKLTIIERLKECGDRRYMPDNNFHSLYVKRHQNVSILYADIVGFTRLASDCSPKEL VVMLNELFGKFDQIAKANECMRIKILGDCYYCVSGLPVSLPTHARNCVKMGLDMCEAIKQ VREATGVDISMRVGIHSGNVLCGVIGLRKWQYDVWSHDVSLANRMEAAGVPGRVHITEAT LKHLDKAYEVEDGHGQQRDPYLKEMNIRTYLVIDPRSQQPPPPSQHLPKPKVDAALKLRA SLRMTRYLESWGAARPFAHLNHRESVSSNETPVPSSRRPKAIPLRRQRTPDRSAPPKGRS EDDSYDDEMLSAIEGLSSTRPCCSKSDDFYTFGSIFLEKGFEREYRLMPIPRARHYFACA SLVFICILLVHVLLMPRTAALGVSFGLVACVLGLVLGLCFADEFLRCCPAWGMLRAISKR VETHPLLRLSLAILTVGSLLTVAIANLLLLPSPVLGPPSGNQTSLRAVSGRERTPCELLP YYTCSCILAFIACSVFLRMSLELKVVLLTVALVAYLVLFNISQCSQWDCCGLGLGNLTKT NATLSSPLACSWRDLKTMISFYLVLFYATLVMLSRQIDYYCRLDCLWKKKFKKEHEEFET MESVNRLLLENVLPAHVAAHFIGDKLDQDWYHQSYDCVCVMFASVPEFKVFYTECDVNKE GLECLRLLNEIIADFDELLLKPKFSSVEKIKTIGSTYMAAAGLSAPSGHENQDLERQHAH IGIMVEFSMALMSKLDGINRHSFNSFRLRVGINHGPVIAGVIGARKPQYDIWGNTVNVAS RMESTGELGKIQVTEETCTILQGLGYSCECRGLINVKGKGELRTYFVCTDTAKFQGLGLN NT seq 3243 nt NT seq  +upstreamnt  +downstreamnt atgcctgccaaggggcgttacttcctcaacgagggtgaggagggcccggaccagaatgcc ctgtacgagaagtatcgtctcaccagccagcacgggccgctgctgctcacgctcctgttg gtggccatcgtggcctgcattgctctcatcatcattgcctttagcgacggggatccctcc agacagcaggctcttctggggacggcgttctcgatgctcgccgtgttcatggttctctac gtgctggtgtacgtcgagtgccttgttcggcagtggctccgggcctcggccctactcatc tgggtctgcctggtgatactgggctacgtgctagtgttcgactcatggatgaaggcgccc tgtgcgtgggagcaggtgcccttcttcctgttcattgtctttgtggcgtacacactgctg cccttcagcatgcagggggccatcgtggcgggggttgtcgccagcgcctcccacctcctg gtgctcggcactctgatgggggtcttctcgtcacccagcatctggatggggctgcagctg ctggccaatgctgtcatcttcctgtgtgggaacctgacgggtgccttccacaagcaccag atgcaggacgcctcccacgacctcttcacctatactgtgaagtgcatccagatccgcagg aagctgcgcatcgagaagcgccagcaggagaacctactgctatcagtgctcccagctcac atctccatgggcatgaagttgaccataattgaacgacttaaggaatgtggggaccgtcgc tacatgcctgacaacaacttccacagcctctacgtcaagcgacaccagaatgtcagcatt ctctacgctgacattgtgggcttcactcggctggccagcgactgctcccccaaagagctg gtggtgatgctgaacgagctcttcggaaagtttgaccagatcgccaaggccaatgagtgc atgcgcatcaagatcctgggtgactgctactactgtgtgtcgggcttgcccgtgtccctg cccacccatgcccggaactgcgtgaagatggggctggacatgtgtgaggccattaagcag gtgcgggaggccacgggcgtggacatcagcatgcgcgtgggcatacactcggggaacgtg ctgtgtggcgtcattgggctgcgcaagtggcagtacgacgtgtggtcccatgacgtgtcc ctcgccaacaggatggaggcggccggagtccccggccgtgtgcatatcacagaggccacg ctgaagcacctggacaaggcgtatgaggtggaggacgggcacgggcagcagcgggacccc tacctgaaggagatgaacatccgcacctacctggtcatcgacccccggagccagcagccg cctccacccagccagcacctccccaagcccaaggtggatgcggccctgaagctgcgggcg tccttgcgcatgacccgctacctggagtcctggggggctgcgcggcccttcgcccacctc aaccaccgagagagtgtgagcagcaacgagacccctgtccccagcagccggaggcccaag gccatccccctgcggcgccaacggacccctgacagaagtgcgccccccaaggggcggtcg gaggacgactcctatgatgacgagatgctgtccgccatcgaggggctcagctccacgagg ccctgctgctccaagtctgatgatttttacacctttgggtccatcttcctggagaagggc ttcgagcgagagtaccgcctgatgcccatcccccgggcccgccactacttcgcctgtgcc agtctcgtctttatctgcatcctgcttgtccacgtcctgctgatgcccaggacggcggct ctgggggtatcctttgggctggtggcctgtgtgctggggctggtgctgggcctgtgcttt gctgatgagttcttgaggtgctgcccagcctgggggatgctccgggctatctccaagagg gtggagactcacccgctgctgcgcttgtccctggccatcctgaccgttggcagcctgctc accgtcgccatcgccaacctgctgttgctgccttccccagtcctggggccaccttctggg aaccagacaagcctgagggccgtgagtggcagggagagaaccccatgcgagctcctcccg tattacacctgcagctgcatcctggccttcatcgcctgctctgtcttcctgaggatgagc ctggagctgaaagttgtgctgctgaccgtggccttggtggcctacctggtgctcttcaac atctcccagtgctcgcagtgggactgctgcggcctcggcctgggcaacctcaccaagacc aacgccaccctcagcagccccctggcctgttcgtggagggatctgaagactatgatcagc ttctacctggttctgttttacgccacccttgtcatgctctccagacagattgactattac tgccgcttggactgcctgtggaagaagaaattcaagaaggaacacgaggagtttgagacc atggagagcgtgaatcgcctgctcctggaaaatgtgctgccggcccatgtggccgcccat ttcatcggggacaagctagaccaggactggtaccatcagtcctacgactgcgtctgtgtc atgttcgcctctgtgccggagttcaaagtgttctacaccgagtgcgacgtcaacaaggag gggctggagtgcctgcgcctgctgaacgagatcatcgccgactttgacgagctgctgtta aagcccaagttcagcagcgtggagaagatcaagacgattggcagcacgtacatggcagct gccggactcagcgccccctcggggcatgagaaccaggacctggagcggcagcatgcccac atcggcatcatggtggagttcagcatggccctgatgagcaagctggacggcatcaacagg cactccttcaactccttccgcctccgcgtcggcataaaccacgggcccgtgattgctggg gtgattggggcacggaagcctcagtacgatatctggggaaacacggtcaatgttgccagc aggatggaaagcactggagaactggggaagatccaggtgaccgaggagacgtgcaccatc ctccagggcctcggttactcttgtgaatgtcgaggactgatcaacgtcaaaggcaaaggg gaactgaggacttactttgtctgcacagacactgccaagtttcaaggactcgggctgaac tga

Miniopterus natalensis (Natal long-fingered bat): 107531740 Help Entry 107531740         CDS       T05883                                  Symbol ADCY4 Name (RefSeq) adenylate cyclase type 4   KO K08044   adenylate cyclase 4 [EC:4.6.1.1] Organism mna  Miniopterus natalensis (Natal long-fingered bat) Pathway mna00230   Purine metabolism mna01100   Metabolic pathways mna01522   Endocrine resistance mna04015   Rap1 signaling pathway mna04020   Calcium signaling pathway mna04022   cGMP-PKG signaling pathway mna04024   cAMP signaling pathway mna04062   Chemokine signaling pathway mna04072   Phospholipase D signaling pathway mna04081   Hormone signaling mna04082   Neuroactive ligand signaling mna04114   Oocyte meiosis mna04211   Longevity regulating pathway mna04213   Longevity regulating pathway - multiple species mna04261   Adrenergic signaling in cardiomyocytes mna04270   Vascular smooth muscle contraction mna04371   Apelin signaling pathway mna04540   Gap junction mna04611   Platelet activation mna04713   Circadian entrainment mna04714   Thermogenesis mna04723   Retrograde endocannabinoid signaling mna04724   Glutamatergic synapse mna04725   Cholinergic synapse mna04727   GABAergic synapse mna04742   Taste transduction mna04750   Inflammatory mediator regulation of TRP channels mna04911   Insulin secretion mna04912   GnRH signaling pathway mna04913   Ovarian steroidogenesis mna04914   Progesterone-mediated oocyte maturation mna04915   Estrogen signaling pathway mna04916   Melanogenesis mna04918   Thyroid hormone synthesis mna04921   Oxytocin signaling pathway mna04923   Regulation of lipolysis in adipocytes mna04925   Aldosterone synthesis and secretion mna04926   Relaxin signaling pathway mna04927   Cortisol synthesis and secretion mna04928   Parathyroid hormone synthesis, secretion and action mna04934   Cushing syndrome mna04935   Growth hormone synthesis, secretion and action mna04970   Salivary secretion mna04971   Gastric acid secretion mna04972   Pancreatic secretion mna04976   Bile secretion mna05032   Morphine addiction mna05163   Human cytomegalovirus infection mna05166   Human T-cell leukemia virus 1 infection mna05200   Pathways in cancer mna05207   Chemical carcinogenesis - receptor activation mna05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:mna00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     107531740 (ADCY4)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     107531740 (ADCY4)    04371 Apelin signaling pathway     107531740 (ADCY4)    04020 Calcium signaling pathway     107531740 (ADCY4)    04072 Phospholipase D signaling pathway     107531740 (ADCY4)    04024 cAMP signaling pathway     107531740 (ADCY4)    04022 cGMP-PKG signaling pathway     107531740 (ADCY4)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     107531740 (ADCY4)    04081 Hormone signaling     107531740 (ADCY4)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     107531740 (ADCY4)   09144 Cellular community - eukaryotes    04540 Gap junction     107531740 (ADCY4)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     107531740 (ADCY4)    04062 Chemokine signaling pathway     107531740 (ADCY4)   09152 Endocrine system    04911 Insulin secretion     107531740 (ADCY4)    04923 Regulation of lipolysis in adipocytes     107531740 (ADCY4)    04912 GnRH signaling pathway     107531740 (ADCY4)    04913 Ovarian steroidogenesis     107531740 (ADCY4)    04915 Estrogen signaling pathway     107531740 (ADCY4)    04914 Progesterone-mediated oocyte maturation     107531740 (ADCY4)    04921 Oxytocin signaling pathway     107531740 (ADCY4)    04926 Relaxin signaling pathway     107531740 (ADCY4)    04935 Growth hormone synthesis, secretion and action     107531740 (ADCY4)    04918 Thyroid hormone synthesis     107531740 (ADCY4)    04928 Parathyroid hormone synthesis, secretion and action     107531740 (ADCY4)    04916 Melanogenesis     107531740 (ADCY4)    04925 Aldosterone synthesis and secretion     107531740 (ADCY4)    04927 Cortisol synthesis and secretion     107531740 (ADCY4)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     107531740 (ADCY4)    04270 Vascular smooth muscle contraction     107531740 (ADCY4)   09154 Digestive system    04970 Salivary secretion     107531740 (ADCY4)    04971 Gastric acid secretion     107531740 (ADCY4)    04972 Pancreatic secretion     107531740 (ADCY4)    04976 Bile secretion     107531740 (ADCY4)   09156 Nervous system    04724 Glutamatergic synapse     107531740 (ADCY4)    04727 GABAergic synapse     107531740 (ADCY4)    04725 Cholinergic synapse     107531740 (ADCY4)    04723 Retrograde endocannabinoid signaling     107531740 (ADCY4)   09157 Sensory system    04742 Taste transduction     107531740 (ADCY4)    04750 Inflammatory mediator regulation of TRP channels     107531740 (ADCY4)   09149 Aging    04211 Longevity regulating pathway     107531740 (ADCY4)    04213 Longevity regulating pathway - multiple species     107531740 (ADCY4)   09159 Environmental adaptation    04713 Circadian entrainment     107531740 (ADCY4)    04714 Thermogenesis     107531740 (ADCY4)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     107531740 (ADCY4)    05207 Chemical carcinogenesis - receptor activation     107531740 (ADCY4)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     107531740 (ADCY4)    05163 Human cytomegalovirus infection     107531740 (ADCY4)   09165 Substance dependence    05032 Morphine addiction     107531740 (ADCY4)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     107531740 (ADCY4)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     107531740 (ADCY4)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     107531740 (ADCY4) Enzymes [BR:mna01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      107531740 (ADCY4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc Adcy_cons_dom AC_N CD52 HNOBA Motif Other DBs NCBI-GeneID:  107531740 NCBI-ProteinID:  XP_016061373 LinkDB All DBs Position Unknown AA seq 1076 aa AA seqDB search MARLFSPRPPPSEDLFYETYYSLSQQYPLLLLLLVIVLCALLALLTVAWASGRELASDPG FLTTVLCALGGFSLLLGLASCEQRLQRWTRPLSGLVWAALLALGHGFLFTGGVVSAWDQV SFFLFVIFTTYAMLPLGMREATAAGLASSLSHLLVLGLYLGPQLDSRPALLPQLAANAVL FLCGNVAGAYHKALMERALRATFREALSSLHSRRRLDTEKKHQEHLLLSILPAYLAQEMK AEIMARLQSGQGSRPESTNNFHSLYVKRHQGVSVLYADIVGFTRLASECSPKELVLMLNE LFGKFDQIAKEHECMRIKILGDCYYCVSGLPLSLPDHAINCVRMGLDMCRAIRKLRAATG VDINMRVGVHSGSVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPGRVHITGATLALLAG AYAVEDAAVEHRDPYLRELGEPTYLVIDPRAEEEEEKGTAGELLSSLEGPKMRPSLLMTR YLESWGAAKPFAHLSHVESPVSTSTPLPEKALASSSPQWSLDRSRTPRGLDDELDTGDAK FFQVIEQLNSQKQWKQSKDFNPLTLYFREKEMEKEYRLSALPAFKYYAACTFLVFLSNFI IQMLVTNRPPALAITYSITFLLFLLLLFVCFSEHLTMCVLKGPKMLHWLPTLSGLVATRP GLRVALGTATILLIFTMAITSLFLPATSNCHFQAFNVSSMNFNLSWELPGSLPLISIPYS MHCCVLGFLSCSLFLHMSFELKLLLLLLWLVASCCLFLHSHAWLSDCLVARLYLGSLDSR PGVLKEPKLMGAISFFIFFFTLLVLARQNEYYCRLDFLWKKKLRQEREETEMMENLTRLL LENVLPAHVAPQFIGQNRRNEDLYHQSYECVCVLFASVPDFKEFYSESNINHEGLECLRL LNEIIADFDELLSKPKFSGVEKIKTIGSTYMAATGLNATSGQDAQQDAERSCSHLGTMVE FAVALGSKLDVINKHSFNNFRLRVGLNHGPVVAGVIGAQKPQYDIWGNTVNVASRMESTG VLGKIQVTEETARALQSLGYTCYSRGVIKVKGKGQLCTYFLNTDLTRVGPPSATLG NT seq 3231 nt NT seq  +upstreamnt  +downstreamnt atggcccgactcttcagtccccggccgccgcccagcgaagacctcttctatgagacctac tatagcctgagccagcagtacccactcctgctcctgctcctggtgatcgtgctctgcgcg ctcctggcgctgcttactgtcgcctgggccagcggcagggagctggcctcagacccgggc ttcctgaccacagtgctgtgtgcgctcggaggcttctccctgctgctgggcctggcttcc tgcgagcagcgactgcagcgctggacgcgccccctctcaggcctcgtgtgggcagcgctg ctggcactaggccatggcttcctgttcaccgggggtgtggtgagcgcctgggaccaggtg tcctttttcctctttgtcatcttcactacgtatgccatgttgcccttgggcatgcgggag gccaccgctgcaggccttgcctcctcactctcacacctgctggtcctcgggctgtatctt ggacctcaactggactcaagacccgcactgctgccgcagttggcagcaaacgcggtgtta ttcctgtgcgggaatgtggctggagcataccacaaggcgctgatggagcgcgcactgcgc gccaccttccgagaggcacttagttccctgcactcgcgccggcggctggacacagagaag aagcaccaggaacaccttctcttgtccatccttcctgcctacttggcccaagagatgaag gcagagatcatggcacggctgcagtctggacaggggtcaaggccagagagcaccaacaac ttccacagcctctatgtcaagaggcaccagggagtcagcgtgctgtatgctgacatagtg ggcttcacacggctggccagtgagtgctccccaaaagagttggtgctcatgctcaatgag ctctttggcaagttcgaccagatcgccaaggagcatgaatgcatgcggatcaagatcctg ggagactgttactactgtgtctccgggctgcccctctccctaccagaccacgccatcaac tgcgtgcgcatggggctggacatgtgccgggccatcaggaaactacgagcggccaccggt gtggatatcaacatgcgcgtgggtgtgcactcgggcagcgtgctctgtggggtcatcgga ctgcagaagtggcagtatgatgtctggtctcacgacgtcacactggccaaccacatggag gcgggtggcgtgccaggacgagtgcatatcacaggggctaccctggccctgctggcagga gcttacgccgtggaggatgcggccgtggagcaccgggacccatacctccgggagctaggg gagcctacatacctggtcatcgacccccgggcagaggaggaggaggaaaagggcactgca ggagagctgctgtcctctctcgagggtcccaagatgcgtccatcactgctgatgacccgc tacctggaatcctggggtgcagccaagccttttgcccacctgagccacgtagagagccct gtgtccacctccactcctctcccggagaaggccctggcttcctccagcccccagtggagc ctggaccggagccgtacaccccggggactagatgatgaactggacactggggatgccaag ttcttccaggtcatcgaacagctcaactctcagaaacagtggaagcagtcaaaggacttc aacccactgaccctgtactttcgagagaaggaaatggagaaagagtatcgactctctgca ctccccgccttcaaatactacgcagcctgcaccttcctggtttttctctccaacttcatc atccagatgctggtgacaaacaggcccccagctctggccatcacctatagcatcaccttc ctcctcttcctcctcctcctcttcgtctgcttctcagagcacctgacgatgtgtgtcttg aaaggccctaagatgctgcactggctgcccacactgtctggcctggtggccacacggccc ggactgcgagttgccctgggcactgccaccatcctcctcatctttaccatggccattacc agcctgttcttaccagcaacatcgaactgccattttcaggctttcaatgtgtcctccatg aatttcaacctctcctgggagctccctgggtccctgcctctcatcagcattccatactcc atgcactgctgcgtgctgggtttcctctcctgctccctttttctgcacatgagcttcgaa ctgaagctgctgctgctcctgctatggctggtggcctcctgctgcctcttcctgcactcc cacgcctggctgtccgactgcctggtcgcccgcctctatctgggctccttggactccagg ccaggggtgctgaaggaacccaaactgatgggagccatctccttcttcatcttcttcttc acactccttgtcttggctcggcagaatgagtattattgccgcctggatttcctgtggaag aagaagctgaggcaggagcgggaggagacagagatgatggagaatctgactcggctgctc ttggagaatgtgctccctgcacatgtggccccccagtttattggccagaaccggcgcaat gaggacctctatcaccagtcctacgagtgtgtttgtgtcctcttcgcctcagtcccagac ttcaaagagttttactctgaatccaacatcaaccatgaggggctagagtgtctgcggctg ctcaatgagatcattgctgattttgatgagctgctttctaagcccaagttcagtggggtg gagaagatcaaaaccatcggcagcacctacatggcagctacaggtttaaatgccacctct ggacaagatgcacagcaggatgctgagcgaagctgcagccaccttggcaccatggtggaa tttgcagtggcccttgggtctaagttggacgttatcaacaagcactcattcaacaacttc cgcttgcgtgtggggttgaaccacggacctgtagtggccggagtgataggggcccagaaa ccacaatatgacatctggggcaacacagtgaatgtcgccagtcgcatggagagtacagga gtcctgggcaagatccaagtgactgaggagacagcccgggccctgcagtccttaggctac acctgctacagcagaggtgttatcaaggtcaaaggcaaagggcagctatgcacctacttc ctgaacacagatttgacacgagttggacctccctcagctaccctaggctga

Miniopterus natalensis (Natal long-fingered bat): 107534062 Help Entry 107534062         CDS       T05883                                  Symbol ADCY3 Name (RefSeq) adenylate cyclase type 3   KO K08043   adenylate cyclase 3 [EC:4.6.1.1] Organism mna  Miniopterus natalensis (Natal long-fingered bat) Pathway mna00230   Purine metabolism mna01100   Metabolic pathways mna01522   Endocrine resistance mna04015   Rap1 signaling pathway mna04020   Calcium signaling pathway mna04022   cGMP-PKG signaling pathway mna04024   cAMP signaling pathway mna04062   Chemokine signaling pathway mna04072   Phospholipase D signaling pathway mna04081   Hormone signaling mna04082   Neuroactive ligand signaling mna04114   Oocyte meiosis mna04211   Longevity regulating pathway mna04213   Longevity regulating pathway - multiple species mna04261   Adrenergic signaling in cardiomyocytes mna04270   Vascular smooth muscle contraction mna04371   Apelin signaling pathway mna04540   Gap junction mna04611   Platelet activation mna04713   Circadian entrainment mna04714   Thermogenesis mna04723   Retrograde endocannabinoid signaling mna04724   Glutamatergic synapse mna04725   Cholinergic synapse mna04727   GABAergic synapse mna04740   Olfactory transduction mna04750   Inflammatory mediator regulation of TRP channels mna04911   Insulin secretion mna04912   GnRH signaling pathway mna04913   Ovarian steroidogenesis mna04914   Progesterone-mediated oocyte maturation mna04915   Estrogen signaling pathway mna04916   Melanogenesis mna04918   Thyroid hormone synthesis mna04921   Oxytocin signaling pathway mna04923   Regulation of lipolysis in adipocytes mna04925   Aldosterone synthesis and secretion mna04926   Relaxin signaling pathway mna04927   Cortisol synthesis and secretion mna04928   Parathyroid hormone synthesis, secretion and action mna04934   Cushing syndrome mna04935   Growth hormone synthesis, secretion and action mna04962   Vasopressin-regulated water reabsorption mna04970   Salivary secretion mna04971   Gastric acid secretion mna04972   Pancreatic secretion mna04976   Bile secretion mna05032   Morphine addiction mna05163   Human cytomegalovirus infection mna05166   Human T-cell leukemia virus 1 infection mna05200   Pathways in cancer mna05207   Chemical carcinogenesis - receptor activation mna05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:mna00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     107534062 (ADCY3)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     107534062 (ADCY3)    04371 Apelin signaling pathway     107534062 (ADCY3)    04020 Calcium signaling pathway     107534062 (ADCY3)    04072 Phospholipase D signaling pathway     107534062 (ADCY3)    04024 cAMP signaling pathway     107534062 (ADCY3)    04022 cGMP-PKG signaling pathway     107534062 (ADCY3)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     107534062 (ADCY3)    04081 Hormone signaling     107534062 (ADCY3)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     107534062 (ADCY3)   09144 Cellular community - eukaryotes    04540 Gap junction     107534062 (ADCY3)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     107534062 (ADCY3)    04062 Chemokine signaling pathway     107534062 (ADCY3)   09152 Endocrine system    04911 Insulin secretion     107534062 (ADCY3)    04923 Regulation of lipolysis in adipocytes     107534062 (ADCY3)    04912 GnRH signaling pathway     107534062 (ADCY3)    04913 Ovarian steroidogenesis     107534062 (ADCY3)    04915 Estrogen signaling pathway     107534062 (ADCY3)    04914 Progesterone-mediated oocyte maturation     107534062 (ADCY3)    04921 Oxytocin signaling pathway     107534062 (ADCY3)    04926 Relaxin signaling pathway     107534062 (ADCY3)    04935 Growth hormone synthesis, secretion and action     107534062 (ADCY3)    04918 Thyroid hormone synthesis     107534062 (ADCY3)    04928 Parathyroid hormone synthesis, secretion and action     107534062 (ADCY3)    04916 Melanogenesis     107534062 (ADCY3)    04925 Aldosterone synthesis and secretion     107534062 (ADCY3)    04927 Cortisol synthesis and secretion     107534062 (ADCY3)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     107534062 (ADCY3)    04270 Vascular smooth muscle contraction     107534062 (ADCY3)   09154 Digestive system    04970 Salivary secretion     107534062 (ADCY3)    04971 Gastric acid secretion     107534062 (ADCY3)    04972 Pancreatic secretion     107534062 (ADCY3)    04976 Bile secretion     107534062 (ADCY3)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     107534062 (ADCY3)   09156 Nervous system    04724 Glutamatergic synapse     107534062 (ADCY3)    04727 GABAergic synapse     107534062 (ADCY3)    04725 Cholinergic synapse     107534062 (ADCY3)    04723 Retrograde endocannabinoid signaling     107534062 (ADCY3)   09157 Sensory system    04740 Olfactory transduction     107534062 (ADCY3)    04750 Inflammatory mediator regulation of TRP channels     107534062 (ADCY3)   09149 Aging    04211 Longevity regulating pathway     107534062 (ADCY3)    04213 Longevity regulating pathway - multiple species     107534062 (ADCY3)   09159 Environmental adaptation    04713 Circadian entrainment     107534062 (ADCY3)    04714 Thermogenesis     107534062 (ADCY3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     107534062 (ADCY3)    05207 Chemical carcinogenesis - receptor activation     107534062 (ADCY3)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     107534062 (ADCY3)    05163 Human cytomegalovirus infection     107534062 (ADCY3)   09165 Substance dependence    05032 Morphine addiction     107534062 (ADCY3)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     107534062 (ADCY3)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     107534062 (ADCY3)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     107534062 (ADCY3) Enzymes [BR:mna01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      107534062 (ADCY3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N HNOBA Peptidase_S49_N Motif Other DBs NCBI-GeneID:  107534062 NCBI-ProteinID:  XP_016064486 LinkDB All DBs Position Unknown AA seq 1145 aa AA seqDB search MPRNQGFSDPEHSAEYSAEYSASLPSDPDRGMGRTHEISVRNWGSCLCLPSFMRLTFVPE SLENLYQTYFRRQRHETLLVLVVFAALFDCYALAMCAVVFSRDKLAPLVVAGVGLVLDIL LYVLCKKGLLPGRVTRKVVPYLLWLLITAQIFSYLSLNFAGLHAAGDTAGWQAFFVFSLF ITLPLGLGPILLLSVASCVVHTLILGVTVAQQQQDRLKGMQLLREILANIFLSLCAITVG IMSYHMADRKHRKAFLEARQSLEVKMNLEEQSQQQENLMLSILPKHVADEMLKDMKKDES QKDQQQFNTMYMYRHENVSILFADIVGFTQLSSTCSAQELVKLLNELFARFDKLAAKYHQ LRIKILGDCYYCICGLPDYREDHAVCSILMGLAMVEAISYVREKTKTGVDMRVGVHTGTV LGGVLGQKRWQYDVWSTDVTVANKMEAGGIPGRVHISQSTLDCLRGEFDVEPGDGGSRCD YLEEKGIETYLIIASKPEVKKTATQNGLNGSALPNGAPASSKPSSPALIETKEPNGSVHT SGSTSEEPEEQDAQADNPSFPNPRRRLRLQDLADRVVDASEDEHELNQLLNEALLERESA QVVKERNTFLLSMRFMDPEMETRYSVEKEKQSGAAFSCSCVVLLCSALVEILIDPWLMTN YVTFVIGELLLLVLTICSLAAIFPRAFPKKLVAFSTWIDRTRWARNTWAMLAIFILVMAN VVDMLSCLQYSMGPNNGTAGIETEGGCMENPKYYNYVAVLSLIATIMLVQVSHMVKLTLM LLVTGAVAVINIYAWCPIFDEYDRRRFQEHDFPVVALEKMQILSTTGLNGTDRLPLVPSK YTMTVMIFIMMLSFYYFSRHVEKLARTLFLWKIEVHDQKERVYEMRRWNEALVTNMLPEH VARHFLGSKKRDEELYSQSYDEIGVMFASLPNFADFYTEESINNGGIECLRFLNEIISDF DSLLDNPKFRVITKIKTIGSTYMAASGVTPDVNTNGFTSSNKEEKSEKERWQHLADLADF ALAMKDTLTNINNQSFNNFMLRIGMNKGGVLAGVIGARKPHYDIWGNTVNVASRMESTGV MGNIQVVEETQAILREYGFRFVRRGPIFVKGKGELLTFFLKGRDKPATFPNGSSVTLPHQ VVDNS NT seq 3438 nt NT seq  +upstreamnt  +downstreamnt atgccgaggaatcagggcttctccgatcccgagcactcggctgagtactctgccgagtac tcggccagcctgccctccgaccccgaccgcggcatgggccggacgcacgagatctcggtg cggaactgggggtcctgcctctgcctgcccagcttcatgcggctgaccttcgtgcccgag tccttggagaacctgtaccagacctacttccggaggcagcgccacgagaccctgctggtg ctggtggtcttcgcagcgctcttcgactgctacgcgctggccatgtgcgccgtggtcttc agccgcgacaagctggcgcccctcgtggtggccggggtcgggctggtgttggacatcctc ctctacgtgctctgcaaaaaggggctgctccccgggcgcgtcacccggaaagtggtgccc tacctgctgtggctgctcattacagcccagatcttctcctacctgagcctgaacttcgcg ggcctgcatgcggccggcgacacggcgggctggcaggccttcttcgtcttctccctcttc atcacgctgcccctgggcctcggccccatcctcctcctctccgtggcttcctgtgttgtg cacacgctgattttgggggtcacggtggcccagcagcagcaggacaggctgaaggggatg cagttgctgagagagatcctggccaacatcttcctctccctgtgcgccatcaccgtgggc atcatgtcctaccacatggcagaccgcaagcaccgcaaggccttcctggaggcccgccag tcgctggaggtgaagatgaacctggaggagcagagccagcagcaggagaaccttatgctg tccatcctgcccaagcacgtggccgacgagatgctgaaggacatgaagaaggacgagagc cagaaggaccagcagcagttcaacaccatgtacatgtaccgccacgagaacgtcagcatc ctcttcgcagacatcgtgggcttcacccagctgtcttctacctgcagcgcccaggagctc gtgaagctgctcaatgagctcttcgcccgcttcgacaagctggcggccaaataccaccag ctgcggattaagatcctgggcgactgctactactgcatctgcggcctgcctgactaccgg gaggaccacgccgtctgctccatcctcatggggctcgccatggtggaggccatctcgtat gttcgggagaagacaaagaccggggtggacatgcgtgtgggggtgcacacgggcacggtg ctggggggtgtcctgggccagaagcgctggcagtatgatgtgtggtctactgacgtcact gtggccaacaagatggaggctggcggcatccccgggcgcgtgcacatctcccagagcacc ctggactgcctgagaggagagttcgacgtggagcccggtgacgggggcagccgctgtgat tacctagaggagaagggcatcgaaacctacctcatcattgcgtccaagccggaggtgaag aaaactgccacccaaaatggcctcaacggctcggctctgccaaacggagcgccagcatcc tcaaagcccagctcccctgccctcatcgagaccaaggagcccaatgggagtgtccacacc agtggctccacgtcagaggagcccgaggagcaggatgcccaggctgacaacccctccttc cccaaccctcgccggaggctgcggcttcaggacctggctgaccgagtggtggacgcctct gaggacgagcacgagctcaaccagctgctcaacgaggccctgctcgagcgggagtcggcc caggtagtgaaggagaggaacaccttcctcctgtccatgcggttcatggaccccgagatg gagacccgctactcggtggagaaggaaaagcagagcggggccgccttcagctgctcctgc gtcgtcctgctctgcagcgccttggtggagattctcatcgacccctggctaatgacaaac tacgtgacgtttgtgattggggaacttctgctactggtcctgacgatctgttcactggct gccatctttccccgggcctttcctaagaagctggtggccttctcgacttggattgaccgg acacgctgggccaggaacacctgggccatgttagccatcttcatcctggttatggcaaat gtcgtggacatgctgagctgcctccaatattccatgggacccaacaatggcactgcaggg atagagacggagggtggttgcatggagaaccccaagtattacaactatgtcgctgtgctg tccctcatcgccaccatcatgctggtgcaagtcagccacatggtgaagctcaccctcatg ctgcttgtcacgggtgcggttgccgtcatcaacatctatgcctggtgccccatctttgat gaatatgaccgcagacgtttccaggaacatgactttcctgtggtcgccttggagaagatg cagatcctctccaccactgggctcaatggcactgacaggctgcccttagtgccttctaag tacacgatgacagtgatgatcttcatcatgatgctgagcttctactacttctcccgccac gtggaaaaactggcacggacattgttcttgtggaagattgaggtccatgaccagaaagaa cgtgtctacgagatgcgacgctggaatgaggccttggtcaccaacatgttgcctgagcat gtggcacgccatttcctggggtccaagaagagagatgaggagctgtatagccagtcttat gatgagattggagttatgtttgcctccctgcccaattttgctgacttctacacagaggag agcatcaataatggtggcattgagtgtctgcgcttcctcaacgagatcatctcagatttt gactctcttctagacaatcccaaattccgggtcatcaccaagatcaaaaccattggcagt acctacatggcagcttcaggagtcaccccagatgtcaacaccaacggcttcaccagctcc aacaaggaggaaaagtcagaaaaggagcgctggcaacacctggctgacctggctgacttt gcactagccatgaaggatacccttacgaacatcaacaaccagtccttcaacaacttcatg ctacgcataggcatgaacaaaggaggggtcctggctggagtcattggagcccggaaacca cactacgacatctggggcaacacagtcaatgtagccagcaggatggagtctacaggggtc atgggcaacattcaggtggtagaagaaacacaagccatccttcgagagtacggcttccgc tttgtgaggcgagggcccatctttgtgaaagggaagggggagctgctaacttttttcttg aaggggcgtgataagccagccaccttcccgaatgggtcctctgtgaccctgccccaccag gtagtagacaactcctga

Miniopterus natalensis (Natal long-fingered bat): 107535777 Help Entry 107535777         CDS       T05883                                  Symbol ADCY9 Name (RefSeq) adenylate cyclase type 9 isoform X1   KO K08049   adenylate cyclase 9 [EC:4.6.1.1] Organism mna  Miniopterus natalensis (Natal long-fingered bat) Pathway mna00230   Purine metabolism mna01100   Metabolic pathways mna01522   Endocrine resistance mna04015   Rap1 signaling pathway mna04020   Calcium signaling pathway mna04022   cGMP-PKG signaling pathway mna04024   cAMP signaling pathway mna04062   Chemokine signaling pathway mna04072   Phospholipase D signaling pathway mna04081   Hormone signaling mna04082   Neuroactive ligand signaling mna04114   Oocyte meiosis mna04211   Longevity regulating pathway mna04213   Longevity regulating pathway - multiple species mna04261   Adrenergic signaling in cardiomyocytes mna04270   Vascular smooth muscle contraction mna04371   Apelin signaling pathway mna04540   Gap junction mna04611   Platelet activation mna04713   Circadian entrainment mna04714   Thermogenesis mna04723   Retrograde endocannabinoid signaling mna04724   Glutamatergic synapse mna04725   Cholinergic synapse mna04727   GABAergic synapse mna04750   Inflammatory mediator regulation of TRP channels mna04911   Insulin secretion mna04912   GnRH signaling pathway mna04913   Ovarian steroidogenesis mna04914   Progesterone-mediated oocyte maturation mna04915   Estrogen signaling pathway mna04916   Melanogenesis mna04918   Thyroid hormone synthesis mna04921   Oxytocin signaling pathway mna04923   Regulation of lipolysis in adipocytes mna04925   Aldosterone synthesis and secretion mna04926   Relaxin signaling pathway mna04927   Cortisol synthesis and secretion mna04928   Parathyroid hormone synthesis, secretion and action mna04934   Cushing syndrome mna04935   Growth hormone synthesis, secretion and action mna04961   Endocrine and other factor-regulated calcium reabsorption mna04962   Vasopressin-regulated water reabsorption mna04970   Salivary secretion mna04971   Gastric acid secretion mna04972   Pancreatic secretion mna04976   Bile secretion mna05032   Morphine addiction mna05163   Human cytomegalovirus infection mna05166   Human T-cell leukemia virus 1 infection mna05200   Pathways in cancer mna05207   Chemical carcinogenesis - receptor activation mna05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:mna00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     107535777 (ADCY9)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     107535777 (ADCY9)    04371 Apelin signaling pathway     107535777 (ADCY9)    04020 Calcium signaling pathway     107535777 (ADCY9)    04072 Phospholipase D signaling pathway     107535777 (ADCY9)    04024 cAMP signaling pathway     107535777 (ADCY9)    04022 cGMP-PKG signaling pathway     107535777 (ADCY9)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     107535777 (ADCY9)    04081 Hormone signaling     107535777 (ADCY9)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     107535777 (ADCY9)   09144 Cellular community - eukaryotes    04540 Gap junction     107535777 (ADCY9)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     107535777 (ADCY9)    04062 Chemokine signaling pathway     107535777 (ADCY9)   09152 Endocrine system    04911 Insulin secretion     107535777 (ADCY9)    04923 Regulation of lipolysis in adipocytes     107535777 (ADCY9)    04912 GnRH signaling pathway     107535777 (ADCY9)    04913 Ovarian steroidogenesis     107535777 (ADCY9)    04915 Estrogen signaling pathway     107535777 (ADCY9)    04914 Progesterone-mediated oocyte maturation     107535777 (ADCY9)    04921 Oxytocin signaling pathway     107535777 (ADCY9)    04926 Relaxin signaling pathway     107535777 (ADCY9)    04935 Growth hormone synthesis, secretion and action     107535777 (ADCY9)    04918 Thyroid hormone synthesis     107535777 (ADCY9)    04928 Parathyroid hormone synthesis, secretion and action     107535777 (ADCY9)    04916 Melanogenesis     107535777 (ADCY9)    04925 Aldosterone synthesis and secretion     107535777 (ADCY9)    04927 Cortisol synthesis and secretion     107535777 (ADCY9)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     107535777 (ADCY9)    04270 Vascular smooth muscle contraction     107535777 (ADCY9)   09154 Digestive system    04970 Salivary secretion     107535777 (ADCY9)    04971 Gastric acid secretion     107535777 (ADCY9)    04972 Pancreatic secretion     107535777 (ADCY9)    04976 Bile secretion     107535777 (ADCY9)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     107535777 (ADCY9)    04961 Endocrine and other factor-regulated calcium reabsorption     107535777 (ADCY9)   09156 Nervous system    04724 Glutamatergic synapse     107535777 (ADCY9)    04727 GABAergic synapse     107535777 (ADCY9)    04725 Cholinergic synapse     107535777 (ADCY9)    04723 Retrograde endocannabinoid signaling     107535777 (ADCY9)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     107535777 (ADCY9)   09149 Aging    04211 Longevity regulating pathway     107535777 (ADCY9)    04213 Longevity regulating pathway - multiple species     107535777 (ADCY9)   09159 Environmental adaptation    04713 Circadian entrainment     107535777 (ADCY9)    04714 Thermogenesis     107535777 (ADCY9)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     107535777 (ADCY9)    05207 Chemical carcinogenesis - receptor activation     107535777 (ADCY9)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     107535777 (ADCY9)    05163 Human cytomegalovirus infection     107535777 (ADCY9)   09165 Substance dependence    05032 Morphine addiction     107535777 (ADCY9)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     107535777 (ADCY9)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     107535777 (ADCY9)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     107535777 (ADCY9) Enzymes [BR:mna01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      107535777 (ADCY9) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N Adcy_cons_dom Motif Other DBs NCBI-GeneID:  107535777 NCBI-ProteinID:  XP_016066833 LinkDB All DBs Position Unknown AA seq 1353 aa AA seqDB search MASPPHQQLLQHHSTEVSCDSSGDNNSVRVKINPKQLSSNSHPKHCKYSISSSCSSSGDS GGVPRRVGAGGRLRRQKKLPQLFERASSRWWDPKFDSVNLEEACLERCFPQTQRRFRYAL FYIGFACLLWSIYFGVHMRSKMIFMAAPALCFLVVCVGFFLFTFTKLYARHYVWTSLVFT LLVFSLTLAAQFQVLTPLSGPVDSSNHTPAAKSTDTCLSQVGSFSMCIEVLFLLYTVMHL PLYLSLFLGVAYSVLFETFGYHFQDEDCFPSPEAGPRHWELLSRALLHVCIHAIGIHLFI MSQVRSRSTFLKVGQSIMHGKDLEVEKALKERMIHSVMPRIIADDLMKQGDEESENSMKR HATSSPKNRKKKSSIQKAPIAFRPFKMQQIEEVSILFADIVGFTKMSANKSAHALVGLLN DLFGRFDRLCEETKCEKISTLGDCYYCVAGCPEPRADHAYCCIEMGLGMIRAIEHFCQEK KEMVNMRVGVHTGTVLCGILGMRRFKFDVWSNDVNLANLMEQLGVAGKVHISEATAKYLD DRYEMEDGRVTERLGQSVVVDQLKGLKTYLIAGQRAKESHCGCSEALLSGFEVIDGSQVS SGPRGQGTTSPGSVSDLAQTVKTFDNLKTCPSCRITFAPKSEAGAEGGAVQNGCQEEHKN NTKVSGGHNSKAQNGLLSPPQEEKLTNSQTSLCEILQEKGKWAGVSLDQSALLPLRFKNI REKTDAHFVDVIKEDSLMKDYFFKPPINQFSLNFLDQELEQAYRTSYQEEVMKNSPVKTF ASATFSSLLDVFLSTTVFLILSITCFLKYGAATTPPPPATLVVFGVALLLEVLSLVVSVR MVFFLEDVMACTKRLLEWIAGWLPRHFIGAILVSLPALAVYSHITSEFETNIHFTVFMGS AILIAVVHYCNFCQLSSWMRSSLATIVGAGPLLLLYISLCPDSSIVMSHFNAVQNFSSER NPCNSSLLHDSRRPASLVGQEMILVFFLLLLLVWFLNREFEVSYRLHYHGDVEADLHRTK IQSMRDQADWLLRNIIPYHVAEQLKVSQTYSKNHDNGGVIFASIVNFSEFYEENYEGGKE CYRVLNELIGDFDELLSKPDYSSIEKIKTIGATYMAASGLNATQCQDGSHPQEHLQILFE FAKEMMRVVDDFNNNMLWFNFKLRVGFNHGPLTAGVIGTTKLLYDIWGDTVNIASRMDTT GVECRIQVSEESYRVLSKMGYDFDYRGTVNVKGKGQMKTYLYPKCTDNGIVPQHQLSISP DIRVQVDGSIGRSPTDEIANLVPSVQNLDKTCLGSENNTQAKDPHLSSKRPWKEPIKAEE RCRFGKAIEKTDCEDMGMEEANELTKLNVSKSV NT seq 4062 nt NT seq  +upstreamnt  +downstreamnt atggcttccccgccccaccagcagctgctgcagcaccacagcaccgaggtgagttgtgat tccagcggagacaacaacagcgtgagggtcaaaatcaaccccaagcagctgtcgtccaac agccaccctaaacactgcaagtacagcatctcctccagttgtagcagctctggggactca gggggcgtcccccggagagtgggcgccggaggccgcctgcgcaggcagaagaagctgccc cagctgttcgagagggcctccagtcggtggtgggaccccaagttcgactcggtgaacctg gaggaggcttgcctggagcgctgcttcccgcaaacccagcgccgcttccggtatgcgctt ttctacataggtttcgcctgcctgctctggagcatctattttggggtccacatgagatcc aaaatgattttcatggcagctcctgctctgtgcttcctcgtggtgtgtgtgggctttttc ctgtttaccttcaccaagctgtatgcccgacattatgtgtggacctcgctggttttcacc ctcctggtgttcagcctgactctggctgcccagtttcaggttctgacgcctctctcggga cctgttgacagttccaatcatactcccgcagctaagtccacagacacttgcttatctcaa gtggggagcttttccatgtgcattgaagttctctttttgctctacaccgtcatgcactta cctttgtacttgagcttgtttttgggagtggcatactctgtactttttgagacctttggc tatcatttccaagatgaagactgcttcccctcacctgaagcagggccccggcactgggag ctgctgagccgagccctgctccatgtctgcattcatgccattgggatccacctattcatc atgtcccaggtgagatctagaagcaccttcctcaaggtgggacagtcaattatgcatggg aaggatctggaagtggaaaaagccctgaaagagaggatgattcattctgtgatgccaaga atcattgctgatgacttgatgaaacagggggatgaggagagtgagaattctatgaaaagg catgccacctccagccccaagaacaggaagaaaaagtcttccatacagaaagcccctata gcattccgcccatttaagatgcagcagattgaagaggtcagtattttatttgcagacatc gtaggcttcaccaagatgagtgccaacaagtctgctcatgccctggtaggtctcctcaat gatctgtttggtcgctttgaccggttgtgtgaagagaccaagtgtgagaaaatcagcacc ctgggagactgctactactgtgtggcagggtgccccgaaccccgggctgaccatgcctat tgctgcattgaaatgggcttgggcatgataagagccatcgagcacttctgccaggagaag aaagaaatggtgaacatgcgtgttggggttcacacggggactgttttgtgtggcatcttg ggcatgaggaggtttaaatttgatgtgtggtccaatgacgtgaacctggccaatctcatg gagcagctgggagtggctggcaaggttcacatttctgaggccactgcaaaataccttgat gatcggtacgaaatggaggatgggagagttactgaacgcctcggccagagcgttgttgtt gaccagttgaaaggtttgaagacatacctgatagcgggtcagagagcgaaggagtctcat tgcggctgttcagaggccttgctttctggctttgaggtcattgacggctcacaggtgtcc tcaggtcctaggggacaggggacaacatcaccagggagtgtcagtgacttggcgcagact gtcaaaacctttgataaccttaagacctgcccttcatgcagaatcacgtttgctcccaaa tcagaagctggtgcagaagggggcgcagtgcaaaatggctgtcaggaggagcataaaaat aacaccaaggtttctggaggacataattccaaagcacaaaacggactcctgagccctccc caagaggaaaaactcaccaatagccagacctccctgtgtgaaatcttacaggaaaaggga aagtgggcaggtgtcagtttggaccagtctgctctcctcccgctgaggttcaagaacatc cgggagaaaacagacgcccactttgttgatgttatcaaagaagacagcctgatgaaagat tatttttttaagccacccattaatcagttcagcttgaacttcctggatcaggagctagag caagcctacagaaccagctatcaagaagaggttatgaaaaattctccggtgaagactttt gctagtgccaccttcagctccctcctggatgtgtttctgtcaacaacagtgtttctgatt ctctccatcacgtgcttcctgaagtacggggctgccaccacgcctcccccgccagccacc ttggtggtctttggggtagccctgctactggaggtgctgtccctcgtggtctctgtcagg atggtgtttttcctggaggatgtgatggcttgtaccaagcgcctgctggagtggatagcc ggctggctgccacgccatttcattggtgccatcctggtgtcacttcccgctctcgcagtc tattcacacatcacttccgaatttgagacaaacatacatttcaccgtgttcatgggctca gccatcctcatcgctgtggtgcactattgtaacttctgccagctcagctcctggatgcgc tcttccttagccaccatcgtcggggctgggcccctgcttctgctctacatctccctgtgc ccagacagttccatagtaatgtcacattttaatgcagtacagaatttcagttccgagagg aatccatgcaatagttcattgctgcatgacagcaggagaccagccagcctggttggccag gagatgattctcgtcttctttctcttgctcttgttggtctggttcctgaatcgagaattt gaagtcagctaccgcctgcactaccatggggatgtggaggcagaccttcaccgcaccaag atccagagcatgagggaccaagccgactggctgctgaggaacatcatcccctaccatgtg gctgagcagctgaaggtttcccagacctactccaagaatcacgacaatgggggagtcatc tttgccagcattgtcaacttcagtgagttctatgaggagaactacgagggaggcaaggag tgctaccgggtcctcaacgagctgataggggacttcgatgaactcctgagcaagccagac tacagcagcattgagaagattaaaaccattggagccacatacatggccgcatcggggctg aatgccacacagtgccaggatggcagccatccacaggaacacctacagattctgtttgag tttgccaaggagatgatgcgtgtggtggatgacttcaacaacaacatgctgtggttcaac ttcaaactcagagttggcttcaaccacggacccttgacagcaggggtcattggcactacc aagctactgtatgacatctggggagacactgtcaacatcgccagcaggatggacaccaca ggagtggagtgccgcatccaagtgagtgaagaaagctaccgggtcctcagcaagatgggc tacgactttgactacaggggcacagtgaatgtcaagggtaagggtcagatgaagacctac ctttacccaaagtgcacagacaacgggatcgtgccacagcaccagctgtccatttcccca gacatccgagtccaggtggacggcagcatcggacggtctcccacagacgagattgccaac ctggtgccttctgtacagaacttggacaagacatgtctgggttctgagaacaacacgcag gccaaggaccctcacctgtcttctaagagaccctggaaagagcctatcaaagccgaagaa aggtgtcgatttggcaaagccatagagaaaactgactgtgaagatatggggatggaagaa gccaatgaactcaccaagctcaatgtctcaaagagtgtatga

Miniopterus natalensis (Natal long-fingered bat): 107539500 Help Entry 107539500         CDS       T05883                                  Symbol ADCY8 Name (RefSeq) adenylate cyclase type 8 isoform X1   KO K08048   adenylate cyclase 8 [EC:4.6.1.1] Organism mna  Miniopterus natalensis (Natal long-fingered bat) Pathway mna00230   Purine metabolism mna01100   Metabolic pathways mna01522   Endocrine resistance mna04015   Rap1 signaling pathway mna04020   Calcium signaling pathway mna04022   cGMP-PKG signaling pathway mna04024   cAMP signaling pathway mna04062   Chemokine signaling pathway mna04072   Phospholipase D signaling pathway mna04081   Hormone signaling mna04082   Neuroactive ligand signaling mna04114   Oocyte meiosis mna04211   Longevity regulating pathway mna04213   Longevity regulating pathway - multiple species mna04261   Adrenergic signaling in cardiomyocytes mna04270   Vascular smooth muscle contraction mna04371   Apelin signaling pathway mna04540   Gap junction mna04611   Platelet activation mna04713   Circadian entrainment mna04714   Thermogenesis mna04720   Long-term potentiation mna04723   Retrograde endocannabinoid signaling mna04724   Glutamatergic synapse mna04725   Cholinergic synapse mna04727   GABAergic synapse mna04742   Taste transduction mna04750   Inflammatory mediator regulation of TRP channels mna04911   Insulin secretion mna04912   GnRH signaling pathway mna04913   Ovarian steroidogenesis mna04914   Progesterone-mediated oocyte maturation mna04915   Estrogen signaling pathway mna04916   Melanogenesis mna04918   Thyroid hormone synthesis mna04921   Oxytocin signaling pathway mna04923   Regulation of lipolysis in adipocytes mna04925   Aldosterone synthesis and secretion mna04926   Relaxin signaling pathway mna04927   Cortisol synthesis and secretion mna04928   Parathyroid hormone synthesis, secretion and action mna04934   Cushing syndrome mna04935   Growth hormone synthesis, secretion and action mna04970   Salivary secretion mna04971   Gastric acid secretion mna04972   Pancreatic secretion mna04976   Bile secretion mna05032   Morphine addiction mna05163   Human cytomegalovirus infection mna05166   Human T-cell leukemia virus 1 infection mna05200   Pathways in cancer mna05207   Chemical carcinogenesis - receptor activation mna05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:mna00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     107539500 (ADCY8)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     107539500 (ADCY8)    04371 Apelin signaling pathway     107539500 (ADCY8)    04020 Calcium signaling pathway     107539500 (ADCY8)    04072 Phospholipase D signaling pathway     107539500 (ADCY8)    04024 cAMP signaling pathway     107539500 (ADCY8)    04022 cGMP-PKG signaling pathway     107539500 (ADCY8)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     107539500 (ADCY8)    04081 Hormone signaling     107539500 (ADCY8)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     107539500 (ADCY8)   09144 Cellular community - eukaryotes    04540 Gap junction     107539500 (ADCY8)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     107539500 (ADCY8)    04062 Chemokine signaling pathway     107539500 (ADCY8)   09152 Endocrine system    04911 Insulin secretion     107539500 (ADCY8)    04923 Regulation of lipolysis in adipocytes     107539500 (ADCY8)    04912 GnRH signaling pathway     107539500 (ADCY8)    04913 Ovarian steroidogenesis     107539500 (ADCY8)    04915 Estrogen signaling pathway     107539500 (ADCY8)    04914 Progesterone-mediated oocyte maturation     107539500 (ADCY8)    04921 Oxytocin signaling pathway     107539500 (ADCY8)    04926 Relaxin signaling pathway     107539500 (ADCY8)    04935 Growth hormone synthesis, secretion and action     107539500 (ADCY8)    04918 Thyroid hormone synthesis     107539500 (ADCY8)    04928 Parathyroid hormone synthesis, secretion and action     107539500 (ADCY8)    04916 Melanogenesis     107539500 (ADCY8)    04925 Aldosterone synthesis and secretion     107539500 (ADCY8)    04927 Cortisol synthesis and secretion     107539500 (ADCY8)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     107539500 (ADCY8)    04270 Vascular smooth muscle contraction     107539500 (ADCY8)   09154 Digestive system    04970 Salivary secretion     107539500 (ADCY8)    04971 Gastric acid secretion     107539500 (ADCY8)    04972 Pancreatic secretion     107539500 (ADCY8)    04976 Bile secretion     107539500 (ADCY8)   09156 Nervous system    04724 Glutamatergic synapse     107539500 (ADCY8)    04727 GABAergic synapse     107539500 (ADCY8)    04725 Cholinergic synapse     107539500 (ADCY8)    04720 Long-term potentiation     107539500 (ADCY8)    04723 Retrograde endocannabinoid signaling     107539500 (ADCY8)   09157 Sensory system    04742 Taste transduction     107539500 (ADCY8)    04750 Inflammatory mediator regulation of TRP channels     107539500 (ADCY8)   09149 Aging    04211 Longevity regulating pathway     107539500 (ADCY8)    04213 Longevity regulating pathway - multiple species     107539500 (ADCY8)   09159 Environmental adaptation    04713 Circadian entrainment     107539500 (ADCY8)    04714 Thermogenesis     107539500 (ADCY8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     107539500 (ADCY8)    05207 Chemical carcinogenesis - receptor activation     107539500 (ADCY8)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     107539500 (ADCY8)    05163 Human cytomegalovirus infection     107539500 (ADCY8)   09165 Substance dependence    05032 Morphine addiction     107539500 (ADCY8)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     107539500 (ADCY8)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     107539500 (ADCY8)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     107539500 (ADCY8) Enzymes [BR:mna01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      107539500 (ADCY8) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc Adcy_cons_dom AC_N TBK1_ULD Motif Other DBs NCBI-GeneID:  107539500 NCBI-ProteinID:  XP_016071485 LinkDB All DBs Position Unknown AA seq 1067 aa AA seqDB search MNVLDVLTKLTLLVLHLSLASAPMDPLKGILLGFFTGIEVVICALVVVRKDTTSHTYLQY SGVVTWVAMTTQILAAGLGYGLLGDGIGYVLFTLFATYSMLPLPLTWAILAGLGTSLLQV VLQVVIPRLAVISINQVVAQAVLFMCMNTAGISISYLSDRAQRQAFLETRRCVEARLRLE TENQRQERLVLSVLPRFVVLEMINDMTNVEDEHLQHQFHRIYIHRYENVSILFADVKGFT NLSTTLSAQELVRMLNELFARFDRLAHEHHCLRIKILGDCYYCVSGLPEPRQDHAHCCVE MGLSMIKTIRYVRSRTKHDVDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIANKLESGG IPGRIHISKATLDCLNGDYNVEEGHGKERNEFLRKHNIETYLIKQPEESLLSLPEDIVKE SVSSSDRRNSGATFTEGSWSPELPFDNIVGKQNTLAALTRNSINLLPNHLAQALHVQSGP EEINKRIEHTIDLRSGDKLRREHIKPFSLMFKDSSLEHKYSQMRDEVFKSNLVCAFIVLL SIAAIQSLLPSSRAMPMAIQFSILIMLHSALVLITTAEDYKCLPLVLRKTCCWINETYLA RNVIIFASILINFLGAILNILWCDFDKSIPLKNLTFNSSAVFTDICSYPEYFVFTGVLAM VTCAVFLRLNSVLKLAVLLIMIAIYALLTETIYAGLFLRYDNLNHSGEDFLGTKEASLLL MAMFLLAVFYHGQQLEYTARLDFLWRVQAKEEINEMKELREHNENMLRNILPSHVARHFL EKDRDNEELYSQSYDAVGVMFASIPGFADFYSQTEMNNQGVECLRLLNEIIADFDELLGE DRFQDIEKIKTIGSTYMAVSGLSPEKQQCEDKWGHLCALADFSLALTESIQEINKHSFNN FELRIGISHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGLSGRIQVPEETYLILKDQG FAFDYRGEIYVKGISEQEGKLKTYFLLGRVQPNPLILPPRRLPGQYSLAAVVLGLVQSLN RQRQKQLLTENNTTGIIKGHYNRRTLLTPSGSEPGTQAEGTDKSDLP NT seq 3204 nt NT seq  +upstreamnt  +downstreamnt atgaacgtgctggacgtgctgaccaaactcaccctcctggtgctccacctgagcctggcc tcggcccccatggacccgctcaagggcatcctgctgggcttcttcacgggcatcgaggtg gtgatctgcgcgctggtggtggtcaggaaggacaccacctcgcacacctacctgcagtac agcggcgtggtcacctgggtggccatgaccacccagatcttggcagcaggccttggctac gggctgctgggcgacggcatcggctatgtgctcttcaccctctttgccacctacagcatg ctgccgctgccgctcacctgggccatcctggccggcctgggcacctcgctgctgcaggtg gtcctccaagtggtgatcccccggctggcggtcatttccatcaaccaggtggtggcccag gcggtgctgttcatgtgcatgaacacggcggggatctccatcagctacctgtcggaccgg gcccagcgccaggccttcctggagacgcggcggtgcgtggaggcccggctgcgcctggag acggaaaaccagagacaggagcggctggtgctgtctgtgctcccccggtttgtcgtcctg gaaatgatcaacgacatgaccaacgtggaagacgagcacctgcagcaccagttccatcgg atctacatccatcgctatgagaatgtcagtattctttttgcagatgttaaaggatttacc aacctctccaccaccctgtctgctcaggagctggtcaggatgctcaacgagctctttgcc agattcgatcgactggcccatgagcatcactgtcttcgcatcaaaatcttaggggactgc tactattgtgtttctggacttcctgagccccgccaggaccatgcccactgctgcgttgaa atgggcctcagcatgatcaaaaccatcaggtatgtgcggtcaaggacgaagcatgacgtt gacatgcgaatcggaatccactcgggctcagtgctgtgtggtgtgttgggcctgcggaag tggcagtttgacgtctggtcttgggacgtggacattgcgaacaaacttgaatctggagga atccccgggaggattcacatttccaaagccacactcgactgcctcaacggtgactataac gtggaagagggccacgggaaggagaggaatgagttcttgaggaagcataacatagagacc tatttaattaagcagcccgaggagagtctgctgtccttgcccgaagacattgtcaaggag tcagtgagctcctcagacaggaggaacagtggggcgacattcacagaagggtcctggagc cccgagctgcccttcgacaacatagtggggaaacagaacactctggctgccctaacaaga aattcaataaatctacttccaaaccatctcgcacaagctttgcatgtccagtcggggcct gaggaaattaacaagcgaatagaacataccatcgacttgcggagtggcgataaattgaga agagagcatatcaagccattctcactgatgtttaaagactccagcctggagcacaagtat tctcagatgagggacgaagtgttcaagtccaacctggtctgcgcctttatcgtcctcctg tccatcgcggccatacaaagcctgcttccttcttcaagggcgatgcccatggccatccag ttttccatcctgatcatgctgcactcggcactggtcctcatcaccacggcggaggattac aagtgtctgcccctggtcctccggaaaacttgctgttggatcaacgagacctatttggcc cggaacgtcatcatcttcgcgtccatcctgattaatttcctgggcgccatcctgaatatc ctgtggtgtgattttgacaagtcgatacccttgaagaacctgactttcaattcctcagct gtgtttacagatatctgctcctacccagagtacttcgtcttcacgggtgtgttggccatg gtgacctgtgcggttttcctccgacttaactctgtcctgaagctggctgtgctgctcatt atgatcgccatctatgccctgctgaccgagaccatctacgcaggtctctttctgcgctat gacaacctgaaccacagtggagaagatttcctggggaccaaggaggcgtcgctgctgctg atggccatgttcctccttgctgtgttctaccatggacagcagctggagtacacagcccgc ctggacttcctctggcgagtgcaggccaaagaggaaatcaacgagatgaaggagctgagg gagcacaacgagaacatgctgcggaacatcctcccgagccacgtggcccgccacttcctg gagaaggaccgcgacaacgaggagctgtattctcagtcctacgatgccgtcggggtgatg ttcgcctccatcccggggttcgccgacttctactctcagaccgagatgaacaaccaagga gtggagtgcctgcgcctgctgaacgagatcatcgctgacttcgatgagctgctcggtgaa gaccggtttcaagacattgaaaagatcaagaccatcggcagcacctacatggctgtctca ggcctgtcacctgaaaagcagcaatgtgaagataagtggggacacctgtgtgccctggcc gacttctctctcgccctgactgaaagcatacaggaaatcaacaagcattcgttcaacaat tttgaactccggattggcatcagccacggctcggtggtagccggcgtcattggcgctaag aaaccacagtacgacatctggggcaaaaccgtgaacctggccagccggatggacagcacc gggctcagcggccggatccaggtcccggaggagacctatctcatcctgaaggaccagggc ttcgccttcgactatcgcggggagatctacgtgaagggcatcagtgagcaggaggggaag ctcaaaacgtactttctcctggggagagtgcagcccaacccgctgatcctgcccccgcgg aggctgccgggccagtactccctggccgccgtggtcctgggccttgtccagtccctcaac aggcaacggcagaagcagctgctcaccgagaacaacaccacgggcatcatcaagggccac tacaaccggcggactttgttgacacccagcgggtcagagcctgggacccaagccgagggc accgacaagtccgatttgccataa

Miniopterus natalensis (Natal long-fingered bat): 107540528 Help Entry 107540528         CDS       T05883                                  Symbol ADCY2 Name (RefSeq) adenylate cyclase type 2   KO K08042   adenylate cyclase 2 [EC:4.6.1.1] Organism mna  Miniopterus natalensis (Natal long-fingered bat) Pathway mna00230   Purine metabolism mna01100   Metabolic pathways mna01522   Endocrine resistance mna04015   Rap1 signaling pathway mna04020   Calcium signaling pathway mna04022   cGMP-PKG signaling pathway mna04024   cAMP signaling pathway mna04062   Chemokine signaling pathway mna04072   Phospholipase D signaling pathway mna04081   Hormone signaling mna04082   Neuroactive ligand signaling mna04114   Oocyte meiosis mna04211   Longevity regulating pathway mna04213   Longevity regulating pathway - multiple species mna04261   Adrenergic signaling in cardiomyocytes mna04270   Vascular smooth muscle contraction mna04371   Apelin signaling pathway mna04540   Gap junction mna04611   Platelet activation mna04713   Circadian entrainment mna04714   Thermogenesis mna04723   Retrograde endocannabinoid signaling mna04724   Glutamatergic synapse mna04725   Cholinergic synapse mna04727   GABAergic synapse mna04750   Inflammatory mediator regulation of TRP channels mna04911   Insulin secretion mna04912   GnRH signaling pathway mna04913   Ovarian steroidogenesis mna04914   Progesterone-mediated oocyte maturation mna04915   Estrogen signaling pathway mna04916   Melanogenesis mna04918   Thyroid hormone synthesis mna04921   Oxytocin signaling pathway mna04922   Glucagon signaling pathway mna04923   Regulation of lipolysis in adipocytes mna04925   Aldosterone synthesis and secretion mna04926   Relaxin signaling pathway mna04927   Cortisol synthesis and secretion mna04928   Parathyroid hormone synthesis, secretion and action mna04934   Cushing syndrome mna04935   Growth hormone synthesis, secretion and action mna04970   Salivary secretion mna04971   Gastric acid secretion mna04972   Pancreatic secretion mna04976   Bile secretion mna05032   Morphine addiction mna05163   Human cytomegalovirus infection mna05166   Human T-cell leukemia virus 1 infection mna05200   Pathways in cancer mna05207   Chemical carcinogenesis - receptor activation mna05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:mna00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     107540528 (ADCY2)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     107540528 (ADCY2)    04371 Apelin signaling pathway     107540528 (ADCY2)    04020 Calcium signaling pathway     107540528 (ADCY2)    04072 Phospholipase D signaling pathway     107540528 (ADCY2)    04024 cAMP signaling pathway     107540528 (ADCY2)    04022 cGMP-PKG signaling pathway     107540528 (ADCY2)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     107540528 (ADCY2)    04081 Hormone signaling     107540528 (ADCY2)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     107540528 (ADCY2)   09144 Cellular community - eukaryotes    04540 Gap junction     107540528 (ADCY2)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     107540528 (ADCY2)    04062 Chemokine signaling pathway     107540528 (ADCY2)   09152 Endocrine system    04911 Insulin secretion     107540528 (ADCY2)    04922 Glucagon signaling pathway     107540528 (ADCY2)    04923 Regulation of lipolysis in adipocytes     107540528 (ADCY2)    04912 GnRH signaling pathway     107540528 (ADCY2)    04913 Ovarian steroidogenesis     107540528 (ADCY2)    04915 Estrogen signaling pathway     107540528 (ADCY2)    04914 Progesterone-mediated oocyte maturation     107540528 (ADCY2)    04921 Oxytocin signaling pathway     107540528 (ADCY2)    04926 Relaxin signaling pathway     107540528 (ADCY2)    04935 Growth hormone synthesis, secretion and action     107540528 (ADCY2)    04918 Thyroid hormone synthesis     107540528 (ADCY2)    04928 Parathyroid hormone synthesis, secretion and action     107540528 (ADCY2)    04916 Melanogenesis     107540528 (ADCY2)    04925 Aldosterone synthesis and secretion     107540528 (ADCY2)    04927 Cortisol synthesis and secretion     107540528 (ADCY2)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     107540528 (ADCY2)    04270 Vascular smooth muscle contraction     107540528 (ADCY2)   09154 Digestive system    04970 Salivary secretion     107540528 (ADCY2)    04971 Gastric acid secretion     107540528 (ADCY2)    04972 Pancreatic secretion     107540528 (ADCY2)    04976 Bile secretion     107540528 (ADCY2)   09156 Nervous system    04724 Glutamatergic synapse     107540528 (ADCY2)    04727 GABAergic synapse     107540528 (ADCY2)    04725 Cholinergic synapse     107540528 (ADCY2)    04723 Retrograde endocannabinoid signaling     107540528 (ADCY2)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     107540528 (ADCY2)   09149 Aging    04211 Longevity regulating pathway     107540528 (ADCY2)    04213 Longevity regulating pathway - multiple species     107540528 (ADCY2)   09159 Environmental adaptation    04713 Circadian entrainment     107540528 (ADCY2)    04714 Thermogenesis     107540528 (ADCY2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     107540528 (ADCY2)    05207 Chemical carcinogenesis - receptor activation     107540528 (ADCY2)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     107540528 (ADCY2)    05163 Human cytomegalovirus infection     107540528 (ADCY2)   09165 Substance dependence    05032 Morphine addiction     107540528 (ADCY2)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     107540528 (ADCY2)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     107540528 (ADCY2)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     107540528 (ADCY2) Enzymes [BR:mna01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      107540528 (ADCY2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc Adcy_cons_dom AC_N HNOBA Motif Other DBs NCBI-GeneID:  107540528 NCBI-ProteinID:  XP_016072788 LinkDB All DBs Position Unknown AA seq 1024 aa AA seqDB search MPIEVEDHVAFLVTVPTALAIFFAIFILVCIESVFKKLLRLFSVVIWICLVAMAYLFMCF GGTVSPWDQVSFFLFIIFVVYTMLPFNMRDAIIASVLTSSSHTIVLSVCLSATPGAKEHL VWQILANVIIFICGNLAGAYHKHLMELALQQTYQDTCNCIKSRIKLEFEKRQQERLLLSL LPAHIAMEMKAEIIQRLQGPKAGQMENTNNFHNLYVKRHTNVSILYADIVGFTRLASDCS PGELVHMLNELFGKFDQIAKENECMRIKILGDCYYCVSGLPISLPNHAKNCVKMGLDMCE AIKKVRDATGVDINMRVGVHSGNVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPGRVHI SSVTLEHLNGAYKVEEGDGEIRDPYLKQHLVKTYFVINPKGERRSPQHLFRPRHTLDGAK MRASVRMTRYLESWGAAKPFAHLHHRDSMTTENGKISTTDVPMGQHNFQNRTLRTKSQKK RFEEELNERMIQAIDGINAQKQWLKSEDIQRISLLFYNKILEKEYRATALPAFKYYVTCA CLIFFCIFIVQVLVLPKTSILGISFGAAFLLLAFILFVCFAGQLLQCSKKASASLLWLLK SSGIIANRPWPRISLTVITTAIILTMAVFNMFFLSDSEEMILPTANTSNTSLSASNNQAA ILRAQSLFFLPYFIYSCILGLISCSVFLRVNYELKMLIMMAALVGYNIIFLHTHAHVLDD YSQVLFERPGIWKDLKTMGSVSLFIFFITLLVLGRQNEYYCRLDFLWKNKFNKEREEIET MENLNRVLLENVLPAHVAEHFLARSLKNEELYHQSYECVCVMFASIPDFKEFYTESDVNK EGLECLRLLNEIIADFDDLLSKPKFSGVEKIKTIGSTYMAATGLSAVPSQEHAQEPERQY MHIGTMVEFAFALVAKLDAINKHSFNDFKLRVGMNHGPVIAGVIGAQKPQYDIWGNTVNV ASRMDSTGVLDKIQVTEETSVILQTLGYTCTCRGIINVKGKGDLKTYFVNTEMSRSLSQS NLAS NT seq 3075 nt NT seq  +upstreamnt  +downstreamnt atgccaatagaggttgaagaccatgtggcatttttagtaacagttcccactgccctggcg attttcttcgcgatcttcatcctggtctgcattgagtccgtgtttaagaagctgctccgc ctcttctcggtggtgatatggatctgtctcgtggccatggcctacctgttcatgtgcttc ggaggcaccgtctctccctgggaccaggtgtcattcttcctcttcatcatcttcgtggtc tacaccatgctgcccttcaacatgcgagatgccatcatcgccagcgtgctcacctcctct tcccataccatcgtgctgagtgtctgcctgtctgcgacacccggggccaaggagcacctg gtttggcagatcctggccaacgtgatcatcttcatctgcgggaacctggcaggagcatac cacaagcacctcatggaacttgctctgcagcaaacatatcaggacacgtgcaattgcatc aagtcccggatcaagctggagtttgaaaaacgtcagcaggagcggctcctgctgtccctg ctgccagctcacatagccatggaaatgaaagctgagattatccagaggctgcagggcccc aaagccggccagatggaaaacacaaacaactttcacaacctgtacgtcaagcggcacacc aatgtcagtatcctatatgctgacattgttgggttcacccggctagccagtgactgctcc ccaggagaactggtccacatgctgaacgaactttttggaaagtttgatcaaattgcaaag gagaatgaatgtatgagaataaaaattttaggagactgctactactgtgtgtctgggctc ccaatctctctcccaaaccatgccaagaattgtgtgaaaatgggactggatatgtgtgaa gccataaagaaagtgagggatgctactggagttgatatcaacatgcgagtgggagtgcac tccgggaatgtcctctgtggcgtgattggcctgcagaagtggcaatatgatgtgtggtca catgacgttaccttggccaatcacatggaagctggaggggtcccaggacgcgtccacatt tcctctgtgaccctggagcacctgaatggagcatacaaagtggaggaaggagacggcgaa atcagggacccatatttaaagcagcacctggtgaaaacctactttgtaatcaaccccaag ggagaaagacggagcccccagcacctctttagacctcgtcacaccctcgatggagccaag atgagggcctccgtgcgcatgacccggtacctggagtcctggggggcggccaagcccttt gcacacctgcaccacagagacagcatgaccacagagaacggcaagatcagcaccacggat gtaccaatgggtcagcataattttcaaaatcgcaccttaagaaccaagtcacaaaagaaa agatttgaagaggaattaaatgaaaggatgattcaagccatcgatggaattaatgcacaa aagcagtggctcaagtctgaagacattcagagaatctcattgcttttctacaataaaata ctggaaaaagagtaccgggccacggcgctgccggcgttcaagtattacgtgacctgtgcc tgtctcattttcttctgcatcttcatcgtgcaggttctcgtgttaccaaaaacgtccatt ctcgggatctcctttggagctgcattcctcctgcttgccttcattctttttgtctgcttt gctggacagcttttgcaatgcagcaaaaaggcctctgcctccctcctgtggcttttgaag tcatcgggcattatcgcaaaccgcccctggcctcggatctccctcacggtcatcaccaca gccatcattttaaccatggccgtgttcaacatgtttttcctgagtgactcagaagaaatg atccttccaactgccaacacatcaaacacaagtctttctgcctcaaataatcaggcagca attctgcgtgcgcaaagcttgtttttccttccgtactttatatacagctgcattctgggg ttgatatcctgctcggttttcctgcgggtgaactacgagttgaagatgctgatcatgatg gcggcgttggtgggctacaacatcatctttctccacactcatgcccacgtcctggacgac tacagccaggtcttatttgagagaccaggcatttggaaagacctgaagaccatgggctca gtgtctctctttatattcttcatcaccctgcttgtcctgggtagacagaatgaatattac tgtaggttggacttcttatggaagaacaagttcaataaagagcgggaggagatagaaacc atggagaacctgaaccgcgtgctgctggagaacgtgcttcctgcgcacgtggccgagcac tttctggccaggagcctgaagaacgaggagttgtaccaccagtcctatgagtgcgtctgc gttatgtttgcttccattccggatttcaaagaattctacacagaatcagatgtcaacaag gaggggctggaatgcctgcggctcctgaatgagattattgctgactttgatgatctgctg tccaagccaaaattcagtggagttgaaaagatcaagaccatcggcagcacatacatggca gcaacgggtctgagcgctgtgcccagccaggagcatgcgcaggagcccgagaggcagtac atgcacatcggcaccatggtggagttcgccttcgcgctggtggccaagctggatgccatc aacaagcactccttcaacgacttcaagctgcgagtgggtatgaaccatgggcctgtaata gctggtgtaattggagctcagaagccgcagtatgacatctggggcaacaccgtaaacgtg gccagtaggatggacagcactggagtcctagacaaaatacaggtgacggaggagacgagc gtcatcctgcagaccctgggctacacgtgcacgtgccgaggcataatcaacgtgaaggga aagggggatctgaagacgtactttgtgaacacggaaatgtcaaggtccctttcccagagc aacttggcttcctga

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