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Entry
map07218          Drug      Pathway                                

Name
HIV protease inhibitors
Class
BRITE hierarchy
Pathway map
map07218  HIV protease inhibitors
map07218

Ortholog table
Compound
C07051  Indinavir
C15659  TMC 126
C15660  A 77003
C15661  A 80987
C15662  Dmp 323
D00427  Ritonavir (JAN/USP/INN)
D00429  Saquinavir (JAN/USP/INN)
D00894  Amprenavir (JAN/USAN/INN)
D00897  Indinavir sulfate (USP)
D00899  Nelfinavir mesylate (USAN/INN)
D01160  Saquinavir mesylate (USP)
D01276  Atazanavir sulfate (JAN/USAN)
D01425  Lopinavir (JAN/USP/INN)
D02497  Fosamprenavir (INN)
D02861  Indinavir sulfate ethanolate (JAN)
D02867  Fosamprenavir calcium hydrate (JAN)
D03253  Brecanavir (USAN)
D03656  Darunavir (USAN/INN)
D03833  Indinavir (USAN)
D03835  Fosamprenavir calcium (USAN)
D03837  Fosamprenavir sodium (USAN)
D03839  Droxinavir hydrochloride (USAN)
D03843  Tipranavir disodium (USAN)
D05538  Mozenavir (INN)
D06478  Darunavir ethanolate (JAN)
D07471  Atazanavir (INN)
D08259  Nelfinavir (INN)
D08605  Tipranavir (INN)
Reference
  Authors
Tanaka C, Kato R (eds).
  Title
[New Pharmacology (4th ed)] (In Japanese)
  Journal
Nankodo (2002)
Reference
PMID:9646869
  Authors
Wlodawer A, Vondrasek J.
  Title
Inhibitors of HIV-1 protease: a major success of structure-assisted drug design.
  Journal
Annu Rev Biophys Biomol Struct 27:249-84 (1998)
DOI:10.1146/annurev.biophys.27.1.249
Reference
  Authors
Brik A, Wong CH.
  Title
HIV-1 protease: mechanism and drug discovery.
  Journal
Org Biomol Chem 1:5-14 (2003)
DOI:10.1039/b208248a
Reference
  Authors
Wynn GH, Zapor MJ, Smith BH, Wortmann G, Oesterheld JR, Armstrong SC, Cozza KL.
  Title
Antiretrovirals, part 1: overview, history, and focus on protease inhibitors.
  Journal
Psychosomatics 45:262-70 (2004)
DOI:10.1176/appi.psy.45.3.262
Reference
  Authors
Sugiura W.
  Title
[Progress in antiretroviral drugs]
  Journal
Uirusu 55:85-94 (2005)
DOI:10.2222/jsv.55.85
Reference
PMID:1799953
  Authors
Mimoto T, Imai J, Tanaka S, Hattori N, Kisanuki S, Akaji K, Kiso Y.
  Title
KNI-102, a novel tripeptide HIV protease inhibitor containing allophenylnorstatine as a transition-state mimic.
  Journal
Chem Pharm Bull (Tokyo) 39:3088-90 (1991)
DOI:10.1248/cpb.39.3088
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