Rousettus aegyptiacus (Egyptian rousette): 107497689 Help Entry 107497689         CDS       T06036                                  Symbol ADCY8 Name (RefSeq) adenylate cyclase type 8 isoform X1   KO K08048   adenylate cyclase 8 [EC:4.6.1.1] Organism ray  Rousettus aegyptiacus (Egyptian rousette) Pathway ray00230   Purine metabolism ray01100   Metabolic pathways ray01522   Endocrine resistance ray04015   Rap1 signaling pathway ray04020   Calcium signaling pathway ray04022   cGMP-PKG signaling pathway ray04024   cAMP signaling pathway ray04062   Chemokine signaling pathway ray04072   Phospholipase D signaling pathway ray04081   Hormone signaling ray04082   Neuroactive ligand signaling ray04114   Oocyte meiosis ray04211   Longevity regulating pathway ray04213   Longevity regulating pathway - multiple species ray04261   Adrenergic signaling in cardiomyocytes ray04270   Vascular smooth muscle contraction ray04371   Apelin signaling pathway ray04540   Gap junction ray04611   Platelet activation ray04713   Circadian entrainment ray04714   Thermogenesis ray04720   Long-term potentiation ray04723   Retrograde endocannabinoid signaling ray04724   Glutamatergic synapse ray04725   Cholinergic synapse ray04727   GABAergic synapse ray04742   Taste transduction ray04750   Inflammatory mediator regulation of TRP channels ray04911   Insulin secretion ray04912   GnRH signaling pathway ray04913   Ovarian steroidogenesis ray04914   Progesterone-mediated oocyte maturation ray04915   Estrogen signaling pathway ray04916   Melanogenesis ray04918   Thyroid hormone synthesis ray04921   Oxytocin signaling pathway ray04923   Regulation of lipolysis in adipocytes ray04925   Aldosterone synthesis and secretion ray04926   Relaxin signaling pathway ray04927   Cortisol synthesis and secretion ray04928   Parathyroid hormone synthesis, secretion and action ray04934   Cushing syndrome ray04935   Growth hormone synthesis, secretion and action ray04970   Salivary secretion ray04971   Gastric acid secretion ray04972   Pancreatic secretion ray04976   Bile secretion ray05032   Morphine addiction ray05163   Human cytomegalovirus infection ray05166   Human T-cell leukemia virus 1 infection ray05200   Pathways in cancer ray05207   Chemical carcinogenesis - receptor activation ray05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:ray00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     107497689 (ADCY8)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     107497689 (ADCY8)    04371 Apelin signaling pathway     107497689 (ADCY8)    04020 Calcium signaling pathway     107497689 (ADCY8)    04072 Phospholipase D signaling pathway     107497689 (ADCY8)    04024 cAMP signaling pathway     107497689 (ADCY8)    04022 cGMP-PKG signaling pathway     107497689 (ADCY8)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     107497689 (ADCY8)    04081 Hormone signaling     107497689 (ADCY8)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     107497689 (ADCY8)   09144 Cellular community - eukaryotes    04540 Gap junction     107497689 (ADCY8)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     107497689 (ADCY8)    04062 Chemokine signaling pathway     107497689 (ADCY8)   09152 Endocrine system    04911 Insulin secretion     107497689 (ADCY8)    04923 Regulation of lipolysis in adipocytes     107497689 (ADCY8)    04912 GnRH signaling pathway     107497689 (ADCY8)    04913 Ovarian steroidogenesis     107497689 (ADCY8)    04915 Estrogen signaling pathway     107497689 (ADCY8)    04914 Progesterone-mediated oocyte maturation     107497689 (ADCY8)    04921 Oxytocin signaling pathway     107497689 (ADCY8)    04926 Relaxin signaling pathway     107497689 (ADCY8)    04935 Growth hormone synthesis, secretion and action     107497689 (ADCY8)    04918 Thyroid hormone synthesis     107497689 (ADCY8)    04928 Parathyroid hormone synthesis, secretion and action     107497689 (ADCY8)    04916 Melanogenesis     107497689 (ADCY8)    04925 Aldosterone synthesis and secretion     107497689 (ADCY8)    04927 Cortisol synthesis and secretion     107497689 (ADCY8)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     107497689 (ADCY8)    04270 Vascular smooth muscle contraction     107497689 (ADCY8)   09154 Digestive system    04970 Salivary secretion     107497689 (ADCY8)    04971 Gastric acid secretion     107497689 (ADCY8)    04972 Pancreatic secretion     107497689 (ADCY8)    04976 Bile secretion     107497689 (ADCY8)   09156 Nervous system    04724 Glutamatergic synapse     107497689 (ADCY8)    04727 GABAergic synapse     107497689 (ADCY8)    04725 Cholinergic synapse     107497689 (ADCY8)    04720 Long-term potentiation     107497689 (ADCY8)    04723 Retrograde endocannabinoid signaling     107497689 (ADCY8)   09157 Sensory system    04742 Taste transduction     107497689 (ADCY8)    04750 Inflammatory mediator regulation of TRP channels     107497689 (ADCY8)   09149 Aging    04211 Longevity regulating pathway     107497689 (ADCY8)    04213 Longevity regulating pathway - multiple species     107497689 (ADCY8)   09159 Environmental adaptation    04713 Circadian entrainment     107497689 (ADCY8)    04714 Thermogenesis     107497689 (ADCY8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     107497689 (ADCY8)    05207 Chemical carcinogenesis - receptor activation     107497689 (ADCY8)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     107497689 (ADCY8)    05163 Human cytomegalovirus infection     107497689 (ADCY8)   09165 Substance dependence    05032 Morphine addiction     107497689 (ADCY8)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     107497689 (ADCY8)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     107497689 (ADCY8)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     107497689 (ADCY8) Enzymes [BR:ray01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      107497689 (ADCY8) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N Adcy_cons_dom TBK1_ULD Motif Other DBs NCBI-GeneID:  107497689 NCBI-ProteinID:  XP_015975308 UniProt:  A0A7J8C0T6 LinkDB All DBs Position Unknown AA seq 1251 aa AA seqDB search MELSDVRCLSGSEELYTIHPTPPAGDGGSGSRPQRLLWQTAVRHITEQRFIHGHRGGGGG GGSAGSGKGSEPAGGPNHHASQLSSDSALPLYSLGPGERAHSAGSTKVFPERSGSGSASG SGGGGDLGFLHLDCAPSNSDFFLSGGYSYRGVIFPTLRNSFKSRDLERLYQRYFLGQRRK SEVVMNVLDVLTKLTLLVLHLSLASAPMDPLKGILLGFFTGIEVVICALVVVRKDTTSHT YLQYSGVVTWVAMTTQIFAAGLGYGLLGDGIGYVLFTLFATYSMLPLPLAWAIVAGLGTS LLQVVLQVVIPRLAVISINQVVAQAVLFMCMNTAGIFISYLSDRAQRQAFLETRRCVEAR LRLETENQRQERLVLSVLPRFVVLEMINDMTNVEDEHLQHQFHRIYIHRYENVSILFADV KGFTNLSTTLSAQELVRMLNELFARFDRLAHEHHCLRIKILGDCYYCVSGLPEPRQDHAH CCVEMGLGMIKTIRYVRSRTKHDVDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIANKL ESGGIPGRIHISKATLDCLGGDYKVEEGHGKERNEFLRKHDIETYLIKQPEESLLALPED IVKESVSASDRRNSGATFVEGSWSPELPFDNIVGKQNTLAALTRNSINLLPNHLAQALHV QSGPEEINKRIEHTIDLRSGDKLRREHIKPFSLMFKDSSLEHKYSQMRDEVFKSNLVCAF IVLLFITAIQSLLPSSRAMPMAIQFSILIMLHSALVLITTAEDYKCLPLVLRKTCCWINE TYLARNVIIFASILINFLGAILNILWCDFDKSIPLKNLTFNSSAVFTDICSYPEYFVFTG VLAMVTCAVFLRLNSVLKLAVLLIMIAVYALLTETIYAGLFLRYDHLTHSGEDFLGTKEA SLLLMAMFLLAVFYHGQQLEYTARLDFLWRVQAKEEINEMKELREHNENMLRNILPSHVA RHFLEKDRDNEELYSQSYDAVGVMFASIPGFADFYSQTEMNNQGVECLRLLNEIIADFDE LLGEDRFQDIEKIKTIGSTYMAVSGLSPEKQQCEDKWGHLCALADFSLALTESIQEINKH SFNNFELRIGISHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSGRIQVPEETYAIL KDQGFAFDYRGEIYVKGISEQEGKIKTYFLLGRVQPNPFILPPRRVPGQYSLAAVVLGLV QSLNRQRQKQLLSENNSTGIIKGHYNRRTLLTPSGPEPGAQAEGADKSDLP NT seq 3756 nt NT seq  +upstreamnt  +downstreamnt atggagctctccgatgtgcgctgcctgagcggcagcgaggaactctacaccatccacccg acgcccccggccggcgacggcgggagcggctctcggccgcagcgtctgctctggcagacg gcggtgcgacacatcaccgagcagcgcttcattcacgggcaccggggcggcggcggcggc ggcgggagcgcaggctccggcaaaggctcggagccggcaggcggccccaaccaccacgct tcgcagctgtccagcgactcggcgctgcccctttactcgctgggccccggggagcgagcg cacagcgccggcagcaccaaagtcttccctgaacgcagtgggagcggcagcgccagcggc agcgggggcgggggcgacctgggcttcctgcacctcgactgcgccccgagcaactcggat ttcttcctcagtgggggctacagctaccgaggggtcatttttcccacgctgcgcaactcg ttcaagtcccgggatctggagcgcctgtaccagcgctatttcctgggccagaggcgcaag tccgaggtggtgatgaatgtgctggacgtgctgaccaaactcaccctgttggttctccac ttgagcctggcctcggcccccatggacccgctcaagggcatcctgctgggcttcttcacg ggcatcgaggtggtgatctgcgccctggtggtggtcaggaaggacaccacctcgcacacg tacctgcagtacagcggcgtggtcacctgggtggccatgaccacccagatcttcgcagca ggccttggctacgggcttctgggcgacggcatcggctacgtgctcttcacgctcttcgcc acctacagcatgctgccgctgccgctcgcctgggccatcgtggcaggcctgggcacctcc ttgctgcaggtggtcctccaagtggtcatcccccggctggcggtcatttccatcaaccag gtggtggcccaggccgtgttattcatgtgtatgaacacagccggaatcttcatcagttac ctgtcagaccgggcccagcgccaggccttcctggagacgcggaggtgtgtggaggccagg ctgcgtctggagacagaaaaccaaagacaggagcggctcgtgctgtccgtgctgccccgg tttgtcgtcctggaaatgatcaacgacatgaccaacgtggaggatgagcacctgcagcac cagttccatcggatctacatccatcgctatgagaacgtcagtattctttttgcagacgtt aaaggatttaccaacctctccacgaccttgtccgcccaggagctggtcaggatgctcaac gagctctttgccagatttgatcgactggcccacgagcatcactgtcttcgcatcaaaatc ctgggggactgctactactgcgtctccgggcttccggagccccgccaggaccacgcccac tgctgtgtggaaatgggcctcggcatgatcaagaccatcaggtatgtgcggtcgaggacg aagcatgacgttgacatgcggatcggaatccactccggctcggtgctgtgtggcgtgttg ggccttcggaagtggcagtttgacgtctggtcttgggacgtggacatcgcgaacaaactc gaatccggaggaatccctgggaggattcacatctccaaagccacactggactgccttggc ggcgactataaggtggaggagggccacggcaaggagaggaacgagttcttgaggaagcac gacatagagacctatttaattaagcagcccgaggagagcctgctggccctgcccgaagac atcgtcaaggagtcggtgagcgcctcggaccggaggaacagtggggccaccttcgtcgaa ggatcctggagccccgagctgcccttcgacaacatagtggggaaacagaacactctggct gccctaacaagaaattcaataaatctacttccaaaccatcttgcacaagctttgcatgtc cagtctgggcctgaggaaattaacaagagaatagaacataccatcgacttgcggagtggc gataaattgagaagagagcatatcaagcctttctcactgatgtttaaagactccagcctg gagcacaagtattctcaaatgagggacgaagttttcaagtcaaacttggtctgtgcgttt atcgttctgctgtttatcacggcaatacaaagtttgcttccttcttcaagggcgatgccc atggccatccagttttccatcctgatcatgctgcactcagctctggttctcatcaccacg gcggaggattataagtgtctgcccctcgtcctccggaaaacttgctgttggatcaacgag acctatttggcccggaacgtcatcattttcgcgtccatcttgatcaatttcctgggcgcc atcctaaatatcctgtggtgtgattttgacaagtcgatccccttgaagaacctgactttc aattcctcagctgtgtttacagatatctgctcctacccagagtacttcgtcttcacaggg gtgttggccatggtgacctgtgcggtgttcctccgacttaactccgtcctcaagctggcc gtgctgctgatcatgatcgccgtctacgccctgctgaccgagaccatctacgcagggctc tttctgcgctatgaccacctgacccacagtggagaggatttcctggggaccaaggaggcg tcgctgctgctgatggccatgttcctccttgccgtgttctaccatggacagcagctggag tacacggcccgcctggacttcctctggcgcgttcaggccaaggaggagatcaacgagatg aaggagctgagggagcacaacgagaacatgctgcgcaacatcctgcccagccacgtggcc cgccacttcctggagaaggaccgggacaacgaggagctgtattctcagtcctacgatgct gtcggggtgatgttcgcctccatcccggggttcgcggacttctactctcagaccgagatg aacaaccagggagtggaatgcctgcgccttctgaacgagatcatcgctgacttcgatgag ctgctcggcgaagaccggtttcaagacatcgagaagatcaagaccatcggcagcacctac atggccgtgtcgggcctgtcacctgaaaaacagcaatgtgaagacaagtggggacacttg tgtgccctggccgacttctctctcgcgctgaccgagagcatacaggagatcaacaagcat tcgttcaacaacttcgaactccggatcggcatcagccacggctccgtggtggccggcgtc atcggcgctaagaaaccgcagtacgacatctggggcaaaaccgtgaacctggccagtcgg atggacagcacgggggtcagcggcaggatccaggtcccagaggagacctacgccatcctg aaggaccagggctttgcctttgactaccgaggggagatctacgtgaagggcatcagcgag caggaaggcaagatcaaaacatactttctcctgggcagggtccagcccaacccgttcatc ctgcccccgagaagggtgcccgggcagtactccttggccgccgtcgtcctgggcctcgtc cagtccctcaacaggcagaggcagaagcagctgctcagcgagaacaacagcacgggcatc atcaagggccattacaaccggcggactttgctcacccccagcgggccggagcctggcgcc caggccgagggcgccgacaagtccgatttgccataa

Rousettus aegyptiacus (Egyptian rousette): 107498014 Help Entry 107498014         CDS       T06036                                  Symbol ADCY4 Name (RefSeq) adenylate cyclase type 4 isoform X7   KO K08044   adenylate cyclase 4 [EC:4.6.1.1] Organism ray  Rousettus aegyptiacus (Egyptian rousette) Pathway ray00230   Purine metabolism ray01100   Metabolic pathways ray01522   Endocrine resistance ray04015   Rap1 signaling pathway ray04020   Calcium signaling pathway ray04022   cGMP-PKG signaling pathway ray04024   cAMP signaling pathway ray04062   Chemokine signaling pathway ray04072   Phospholipase D signaling pathway ray04081   Hormone signaling ray04082   Neuroactive ligand signaling ray04114   Oocyte meiosis ray04211   Longevity regulating pathway ray04213   Longevity regulating pathway - multiple species ray04261   Adrenergic signaling in cardiomyocytes ray04270   Vascular smooth muscle contraction ray04371   Apelin signaling pathway ray04540   Gap junction ray04611   Platelet activation ray04713   Circadian entrainment ray04714   Thermogenesis ray04723   Retrograde endocannabinoid signaling ray04724   Glutamatergic synapse ray04725   Cholinergic synapse ray04727   GABAergic synapse ray04742   Taste transduction ray04750   Inflammatory mediator regulation of TRP channels ray04911   Insulin secretion ray04912   GnRH signaling pathway ray04913   Ovarian steroidogenesis ray04914   Progesterone-mediated oocyte maturation ray04915   Estrogen signaling pathway ray04916   Melanogenesis ray04918   Thyroid hormone synthesis ray04921   Oxytocin signaling pathway ray04923   Regulation of lipolysis in adipocytes ray04925   Aldosterone synthesis and secretion ray04926   Relaxin signaling pathway ray04927   Cortisol synthesis and secretion ray04928   Parathyroid hormone synthesis, secretion and action ray04934   Cushing syndrome ray04935   Growth hormone synthesis, secretion and action ray04970   Salivary secretion ray04971   Gastric acid secretion ray04972   Pancreatic secretion ray04976   Bile secretion ray05032   Morphine addiction ray05163   Human cytomegalovirus infection ray05166   Human T-cell leukemia virus 1 infection ray05200   Pathways in cancer ray05207   Chemical carcinogenesis - receptor activation ray05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:ray00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     107498014 (ADCY4)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     107498014 (ADCY4)    04371 Apelin signaling pathway     107498014 (ADCY4)    04020 Calcium signaling pathway     107498014 (ADCY4)    04072 Phospholipase D signaling pathway     107498014 (ADCY4)    04024 cAMP signaling pathway     107498014 (ADCY4)    04022 cGMP-PKG signaling pathway     107498014 (ADCY4)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     107498014 (ADCY4)    04081 Hormone signaling     107498014 (ADCY4)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     107498014 (ADCY4)   09144 Cellular community - eukaryotes    04540 Gap junction     107498014 (ADCY4)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     107498014 (ADCY4)    04062 Chemokine signaling pathway     107498014 (ADCY4)   09152 Endocrine system    04911 Insulin secretion     107498014 (ADCY4)    04923 Regulation of lipolysis in adipocytes     107498014 (ADCY4)    04912 GnRH signaling pathway     107498014 (ADCY4)    04913 Ovarian steroidogenesis     107498014 (ADCY4)    04915 Estrogen signaling pathway     107498014 (ADCY4)    04914 Progesterone-mediated oocyte maturation     107498014 (ADCY4)    04921 Oxytocin signaling pathway     107498014 (ADCY4)    04926 Relaxin signaling pathway     107498014 (ADCY4)    04935 Growth hormone synthesis, secretion and action     107498014 (ADCY4)    04918 Thyroid hormone synthesis     107498014 (ADCY4)    04928 Parathyroid hormone synthesis, secretion and action     107498014 (ADCY4)    04916 Melanogenesis     107498014 (ADCY4)    04925 Aldosterone synthesis and secretion     107498014 (ADCY4)    04927 Cortisol synthesis and secretion     107498014 (ADCY4)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     107498014 (ADCY4)    04270 Vascular smooth muscle contraction     107498014 (ADCY4)   09154 Digestive system    04970 Salivary secretion     107498014 (ADCY4)    04971 Gastric acid secretion     107498014 (ADCY4)    04972 Pancreatic secretion     107498014 (ADCY4)    04976 Bile secretion     107498014 (ADCY4)   09156 Nervous system    04724 Glutamatergic synapse     107498014 (ADCY4)    04727 GABAergic synapse     107498014 (ADCY4)    04725 Cholinergic synapse     107498014 (ADCY4)    04723 Retrograde endocannabinoid signaling     107498014 (ADCY4)   09157 Sensory system    04742 Taste transduction     107498014 (ADCY4)    04750 Inflammatory mediator regulation of TRP channels     107498014 (ADCY4)   09149 Aging    04211 Longevity regulating pathway     107498014 (ADCY4)    04213 Longevity regulating pathway - multiple species     107498014 (ADCY4)   09159 Environmental adaptation    04713 Circadian entrainment     107498014 (ADCY4)    04714 Thermogenesis     107498014 (ADCY4)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     107498014 (ADCY4)    05207 Chemical carcinogenesis - receptor activation     107498014 (ADCY4)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     107498014 (ADCY4)    05163 Human cytomegalovirus infection     107498014 (ADCY4)   09165 Substance dependence    05032 Morphine addiction     107498014 (ADCY4)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     107498014 (ADCY4)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     107498014 (ADCY4)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     107498014 (ADCY4) Enzymes [BR:ray01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      107498014 (ADCY4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc Adcy_cons_dom AC_N CD52 Motif Other DBs NCBI-GeneID:  107498014 NCBI-ProteinID:  XP_015976043 LinkDB All DBs Position Unknown AA seq 1077 aa AA seqDB search MPRLFSPRPPPSEDLFYETYYSLSQQYPLLLLLLVIVLSTLLALLAVAWASGRELASDRG FLTTVLCALGGFSLLLGLASREQRLQRWTRPLSGLVWVALLALGHGFLFTGGVVSAWDQV SFFIFVIFTTYAMLPLGMRDAAAAGLTSSLSHLLVLGLYLGPQPDSRPALLPQLAANAVL FLCGNVAGAYHKALMERALRATFREALSSLHSRRRLDTEKKHQEHLLLSILPAYLAREMK AEIMARLQAGQGSRPESTNNFHSLYVKRHQGVSVLYADIVGFTRLASECSPKELVLMLNE LFGKFDQIAKEHECMRIKILGDCYYCVSGLPLSLPDHAINCVRMGLDMCRAIRKLRAATG VDINMRVGVHSGSVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPGRVHITGATLALLAG AYAVEDVAMEHRDPYLRELGETTYLVIDPRAEEEDEKGTAGGLLSSLEGPKMRPSLLMTR YLESWGAAKPFAHLSHVESPVSTSTPLPEKALASFSPQWSLDRSRTPRGLDDELDTGDAK FFQVIEQLNSQKQWKQSKDFNPLTLYFREKEMEKEYRLSALPAFRYYAACTFLVFLSNFI IQMLVTNRPPALAITYSITFLLFLLLLFACFSEHLTRCVLKGPKMLHWLPALSGLVATRP GLRVALGTATILLVFSMAITSLFFLPAASNCPFPAPNVSSEAFNLSWELPGSLPLISIPY SMHCCVLGSLSCSLFLHMSFELKLLLLLLWLVASCSLFLHSHAWLSDCLVARLYLGPLDS RPGVLKEPKLMGAISFFIFFFTLLVLARQNEYYCRLDFLWKKKLRQEREETEMMENLTRL LLENVLPAHVAPQFIGQNRRNEDLYHQSYECVCVLFASVPDFKEFYSESNINHEGLECLR LLNEIIADFDELLSKPKFSGVEKIKTICSTYMAATGLNATSGQDAQQDAERSCSHLGTMV EFAVALGSKLDVINKHSFNNFRLRVGLNHGPVVAGVIGAQKPQYDIWGNTVNVASRMEST GVLGKIQVTEETARALQSLGYTCYSRGVIKVKGKGQLCTYFLNTDLTRAGPPSATLG NT seq 3234 nt NT seq  +upstreamnt  +downstreamnt atgcctcgcctcttcagtcctcggccaccgcccagcgaagacctcttctatgagacctac tacagcttgagccagcagtacccactgctgctactgctgctggtgatcgtgctctccaca ctcctggcattgctagctgtcgcctgggccagcggcagggagctggcttcggacaggggc ttcctgaccacagtgctatgcgcgctgggagggttctcgctgctgctgggcctggcttcc cgcgagcagcgactgcagcgctggactcgtcccctctccggcctcgtgtgggtagcgtta ctcgcgctaggccacggcttcctgttcaccggaggcgtagtgagcgcctgggaccaggtg tcctttttcatctttgtcatcttcaccacgtatgccatgctgcccttgggcatgcgggac gccgccgccgcgggcctcacttcatcgctctcacacctgctggtcctcgggctgtatctt gggcctcagccagactcacgaccggcgctgctgcctcagctggcagcaaacgcggtgctc ttcctgtgcgggaacgtggccggggcgtatcacaaagcgctgatggagcgggcgctgcgc gccaccttccgagaggcgcttagttccctgcactctcgccggaggctggacaccgagaag aagcatcaggaacaccttctcttgtccatccttcctgcctacttggcccgagagatgaag gcggagatcatggcaaggctgcaggctggacaggggtcacggccagagagcaccaacaac ttccacagcctttatgtaaagaggcaccagggagtcagcgtgctgtatgctgacatcgtg ggcttcacgcggctggcaagtgaatgctccccaaaggagttggtgctcatgctcaacgag ctctttggcaagttcgaccagattgccaaggagcatgaatgcatgcggatcaagatcctg ggagactgttactactgtgtctctgggctgccgctctcgctgccagaccacgccatcaac tgtgtgcgcatggggctggacatgtgccgggccatcagaaaattgcgggcagccaccggt gttgatatcaacatgcgcgtgggcgtgcactcgggcagcgtgctctgtggagtcatcggg ctgcagaagtggcagtatgatgtgtggtcccatgatgtcacactggccaaccacatggag gcaggtggcgtgccaggacgagtgcatatcacaggggctactctggccctgctggcagga gcttacgctgtggaggatgtagccatggaacaccgggacccataccttcgagagctaggg gagactacctacctggtcatcgatccccgggccgaggaggaggatgagaagggcactgcg ggagggttgctatcctctctcgaaggtcccaagatgcgtccatcactgctgatgacccgc tatctggagtcctggggtgcagccaagccttttgcgcatctgagccacgtagagagccct gtgtccacctccacccctctgccggagaaagccctggcttccttcagcccccagtggagc ctggaccggagccgtaccccccggggactagatgatgaactggacaccggggatgccaag ttcttccaggtcatcgaacagctcaactctcagaaacagtggaagcagtcaaaggacttc aacccactgacattgtacttccgagagaaggagatggagaaagagtatcgactctccgca ctccctgccttcagatactacgcagcctgcaccttcctggtttttctctccaacttcatc atccagatgctggtgacaaacaggcccccagctctggccatcacctatagcatcaccttc ctcctcttcctcctcctcctcttcgcctgcttctcagagcacctgacgaggtgtgtcttg aaaggccccaagatgctgcactggctgcccgcgctgtctggcctggtggccacacggccc ggactgcgggttgccctgggcactgccaccatcctccttgtcttttccatggccattacc agcctgttcttcttaccagcagcatcgaactgccctttcccggcgcccaatgtgtcctct gaggctttcaacctctcctgggagctccctgggtccttgcctctcatcagcatcccatac tccatgcactgctgtgtgctgggttccctctcctgctccctctttctgcacatgagcttt gaactgaagctgctgctgctcctgctgtggctggtggcctcctgctccctcttcctgcat tcgcacgcctggctgtcggattgcctcgttgcccgcctctatctcggccccttagactcc aggccaggggtgctcaaggagcccaaactcatgggagctatctccttcttcatcttcttc ttcacactccttgtcttggctcggcagaatgagtattattgccgcctggacttcctgtgg aagaagaagctgaggcaggagagggaggagacagagatgatggagaacctgactcggctg ctcttggaaaacgtgcttccagcgcacgtggccccccagttcattggccagaaccggcgc aatgaggacctctaccaccagtcctacgagtgtgtctgcgtcctcttcgcctcagtccca gactttaaggagttttactctgaatctaacatcaaccatgaggggctagagtgtctgcgg ctgctcaatgagatcattgctgatttcgatgagctgctctctaagcccaagttcagtggg gtggaaaagatcaaaacgatttgcagcacctacatggcagctacaggcttaaatgccacc tctggacaggacgcacagcaggatgctgagcgaagctgcagccaccttggcaccatggtg gagtttgcggtggcccttgggtctaagctggatgtcatcaacaagcactcattcaacaac ttccgcctgcgtgtgggattgaaccacggacctgtggtggctggagtaataggggcccag aagccacaatatgacatctggggtaacacagtgaatgtggccagccgcatggagagtaca ggagtcctgggcaagatccaagtgactgaggagacagcccgtgccctgcagtccttaggt tacacttgctacagccggggtgtcatcaaggtcaaaggcaaagggcaactgtgcacctac ttcctgaacacggatttgacacgagctggacctccttcagccaccctgggctga

Rousettus aegyptiacus (Egyptian rousette): 107498506 Help Entry 107498506         CDS       T06036                                  Symbol ADCY3 Name (RefSeq) adenylate cyclase type 3 isoform X2   KO K08043   adenylate cyclase 3 [EC:4.6.1.1] Organism ray  Rousettus aegyptiacus (Egyptian rousette) Pathway ray00230   Purine metabolism ray01100   Metabolic pathways ray01522   Endocrine resistance ray04015   Rap1 signaling pathway ray04020   Calcium signaling pathway ray04022   cGMP-PKG signaling pathway ray04024   cAMP signaling pathway ray04062   Chemokine signaling pathway ray04072   Phospholipase D signaling pathway ray04081   Hormone signaling ray04082   Neuroactive ligand signaling ray04114   Oocyte meiosis ray04211   Longevity regulating pathway ray04213   Longevity regulating pathway - multiple species ray04261   Adrenergic signaling in cardiomyocytes ray04270   Vascular smooth muscle contraction ray04371   Apelin signaling pathway ray04540   Gap junction ray04611   Platelet activation ray04713   Circadian entrainment ray04714   Thermogenesis ray04723   Retrograde endocannabinoid signaling ray04724   Glutamatergic synapse ray04725   Cholinergic synapse ray04727   GABAergic synapse ray04740   Olfactory transduction ray04750   Inflammatory mediator regulation of TRP channels ray04911   Insulin secretion ray04912   GnRH signaling pathway ray04913   Ovarian steroidogenesis ray04914   Progesterone-mediated oocyte maturation ray04915   Estrogen signaling pathway ray04916   Melanogenesis ray04918   Thyroid hormone synthesis ray04921   Oxytocin signaling pathway ray04923   Regulation of lipolysis in adipocytes ray04925   Aldosterone synthesis and secretion ray04926   Relaxin signaling pathway ray04927   Cortisol synthesis and secretion ray04928   Parathyroid hormone synthesis, secretion and action ray04934   Cushing syndrome ray04935   Growth hormone synthesis, secretion and action ray04962   Vasopressin-regulated water reabsorption ray04970   Salivary secretion ray04971   Gastric acid secretion ray04972   Pancreatic secretion ray04976   Bile secretion ray05032   Morphine addiction ray05163   Human cytomegalovirus infection ray05166   Human T-cell leukemia virus 1 infection ray05200   Pathways in cancer ray05207   Chemical carcinogenesis - receptor activation ray05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:ray00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     107498506 (ADCY3)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     107498506 (ADCY3)    04371 Apelin signaling pathway     107498506 (ADCY3)    04020 Calcium signaling pathway     107498506 (ADCY3)    04072 Phospholipase D signaling pathway     107498506 (ADCY3)    04024 cAMP signaling pathway     107498506 (ADCY3)    04022 cGMP-PKG signaling pathway     107498506 (ADCY3)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     107498506 (ADCY3)    04081 Hormone signaling     107498506 (ADCY3)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     107498506 (ADCY3)   09144 Cellular community - eukaryotes    04540 Gap junction     107498506 (ADCY3)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     107498506 (ADCY3)    04062 Chemokine signaling pathway     107498506 (ADCY3)   09152 Endocrine system    04911 Insulin secretion     107498506 (ADCY3)    04923 Regulation of lipolysis in adipocytes     107498506 (ADCY3)    04912 GnRH signaling pathway     107498506 (ADCY3)    04913 Ovarian steroidogenesis     107498506 (ADCY3)    04915 Estrogen signaling pathway     107498506 (ADCY3)    04914 Progesterone-mediated oocyte maturation     107498506 (ADCY3)    04921 Oxytocin signaling pathway     107498506 (ADCY3)    04926 Relaxin signaling pathway     107498506 (ADCY3)    04935 Growth hormone synthesis, secretion and action     107498506 (ADCY3)    04918 Thyroid hormone synthesis     107498506 (ADCY3)    04928 Parathyroid hormone synthesis, secretion and action     107498506 (ADCY3)    04916 Melanogenesis     107498506 (ADCY3)    04925 Aldosterone synthesis and secretion     107498506 (ADCY3)    04927 Cortisol synthesis and secretion     107498506 (ADCY3)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     107498506 (ADCY3)    04270 Vascular smooth muscle contraction     107498506 (ADCY3)   09154 Digestive system    04970 Salivary secretion     107498506 (ADCY3)    04971 Gastric acid secretion     107498506 (ADCY3)    04972 Pancreatic secretion     107498506 (ADCY3)    04976 Bile secretion     107498506 (ADCY3)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     107498506 (ADCY3)   09156 Nervous system    04724 Glutamatergic synapse     107498506 (ADCY3)    04727 GABAergic synapse     107498506 (ADCY3)    04725 Cholinergic synapse     107498506 (ADCY3)    04723 Retrograde endocannabinoid signaling     107498506 (ADCY3)   09157 Sensory system    04740 Olfactory transduction     107498506 (ADCY3)    04750 Inflammatory mediator regulation of TRP channels     107498506 (ADCY3)   09149 Aging    04211 Longevity regulating pathway     107498506 (ADCY3)    04213 Longevity regulating pathway - multiple species     107498506 (ADCY3)   09159 Environmental adaptation    04713 Circadian entrainment     107498506 (ADCY3)    04714 Thermogenesis     107498506 (ADCY3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     107498506 (ADCY3)    05207 Chemical carcinogenesis - receptor activation     107498506 (ADCY3)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     107498506 (ADCY3)    05163 Human cytomegalovirus infection     107498506 (ADCY3)   09165 Substance dependence    05032 Morphine addiction     107498506 (ADCY3)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     107498506 (ADCY3)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     107498506 (ADCY3)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     107498506 (ADCY3) Enzymes [BR:ray01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      107498506 (ADCY3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N HNOBA Peptidase_S49_N Motif Other DBs NCBI-GeneID:  107498506 NCBI-ProteinID:  XP_015977196 LinkDB All DBs Position Unknown AA seq 1145 aa AA seqDB search MPRNQGFSDPEYSAEYSAEYSVSLPSDPERGVGRTHEISVRNSGSCLCLPRFMRLTFVPE SLENLYQTYFKRQRHETLLVLVVFAALFDCYVVVMCAVVFSRDQLAPLVAAGIWLLLDVI LFVLCKKGLLPVRVTRKVVPYLLWLLITAQIFSYLGLNFAGAHAASDTVGWQAFFVFSFF ITLPLSLSPIVVISVVSCVVHTLVLGVTVAQQQQDGLKGMRLLREILASVFLYLGAIIVG ITSYYMADRKHRKAFLEARQSLEVKMNLEEQSQQQENLMLSILPKHVADEMLKDMKKDES QKDQQQFNTMYMYRHENVSILFADIVGFTQLSSACSAQELVKLLNELFARFDKLAAKYHQ LRIKILGDCYYCICGLPDYREDHAVCSILMGLAMVEAISYVREKTKTGVDMRVGVHTGTV LGGVLGQKRWQYDVWSTDVTVANKMEAGGIPGRVHISQSTLDCLKGEFDVEPGDGGSRCD YLDEKGIETYLVIASKPEVKKTAVQNGLNGSALPNGAPPSSQPSSPALIETKEPNGSVHA SGSTSDEPEEQGAQADNPSFPNPRRRLRLQDLADRVVDASEDEHELNQLLNEALLERESA QVVKKRNTFLLSMRFMEPEMETRYSVEKEKQSGAAFSCSCVVLLCAAVAEMLIDPWLMTN YVTFVVGEVLLLILTICSLAAIFPQAFPKKLVAFSTWIDRTRWARNTWAMLAIFILVMAN VVDMLSCLQFYAGPSNGTAGTGLEDGCAANPEYYDDVAVLSLVATIMLVQVSHMVKLTLM LLIAGAVAVVNIYAWRPIFDEYDRRRFQEHDFPVVALEKMQILSTAGLNGTDRLPLLPSK YSMTAMIFVMMLSFYYFSRHVEKLARTLFLWKIEVHDQKERVYEMRRWNEALVTNMLPEH VARHFLGSKKRDEELYSQSYDEIGVMFASLPNFADFYTEESINNGGIECLRFLNEIISDF DSLLDNPKFRVITKIKTIGSTYMAASGVTPDVNTNGFTSSNKEEKSDKERWQHLADLADF ALAMKDTLTNINNQSFNNFMLRIGMNKGGVLAGVIGARKPHYDIWGNTVNVASRMESTGV MGNIQVVEDTQAILREYGFRFVRRGPIFVKGKGELLTFFLKGRDKPATFPNGSSVTLPHQ VVDNS NT seq 3438 nt NT seq  +upstreamnt  +downstreamnt atgccgaggaaccagggcttctccgaccccgagtactcggccgagtactccgccgagtac tccgtcagcctaccctctgacccggagcgcggggtgggccggacccatgaaatctctgtg cggaactcggggtcctgcctctgcctgcctcgctttatgcggctgaccttcgtgcccgag tccttggagaacctgtaccagacctatttcaaaaggcagcgccacgagaccctgctggtg ctggtggtcttcgcagccctcttcgactgctacgtggtggtcatgtgcgccgtggtcttc tcccgcgaccagctggctcccctcgtggcggctgggatctggctgctgttggatgtcatc ctcttcgtgctctgcaaaaaggggctgctcccggtccgggtcacccggaaagtggtgccc tacctactgtggctgctgataacggcccagatcttctcctacttgggcctgaacttcgcg ggcgcccacgcagccagcgacacggtgggctggcaggccttctttgtcttctccttcttc atcacgctgcccctcagcctcagccccatcgtggtcatctctgtggtctcctgtgtggtg cacacgctcgtcttgggggtcaccgtggcccagcagcagcaggatgggctgaaggggatg cggttgctgagagagatcctggccagtgtctttctgtacctcggcgccatcatcgtgggc atcacgtcctactacatggcagaccgcaagcaccgcaaggccttcctggaggcccgccag tcgctggaggtgaagatgaacctggaggagcagagccagcagcaggagaaccttatgctc tccatcctgcccaagcacgtggctgacgagatgctcaaggacatgaagaaggacgagagc cagaaggaccagcagcagttcaacaccatgtacatgtaccggcacgagaacgtcagcatc ctgttcgcggacatcgtgggcttcacccagctgtcctctgcctgcagcgcacaggagctc gtgaagctgctcaacgagctcttcgcccgtttcgacaagctggcggccaaatatcaccag ctgcggatcaagatcctgggcgactgttactattgcatctgtggcctgcccgactaccgc gaggaccacgccgtctgctccatcctcatggggctcgccatggtggaggccatctcgtat gtgcgagagaagacgaagaccggggtggacatgcgtgtgggggtgcacacgggcaccgtg ctgggcggcgtcctgggccagaagcgctggcagtacgacgtgtggtccactgacgtgacc gtggccaacaagatggaggccggcggcatccccgggcgtgtgcacatctcacagagcacc ttggactgcctgaagggagagttcgacgtggagccgggcgacgggggcagccgctgcgat tacctggatgagaagggcatcgaaacctacctcgtcatcgcctccaagccagaggtgaag aaaacggccgtccaaaatggcctcaatggctcggccctgcccaatggagcccccccttcc tcgcagcccagctcccccgccctcatcgagaccaaggagcccaacgggagtgtccacgcc agcgggtccacgtcggacgagcccgaggagcaaggggcccaggccgacaacccctccttc cccaaccctcgccggaggctgcgcctccaggacctggccgaccgcgtggtcgacgcctcc gaggacgagcatgagctcaaccagctgctcaacgaggcgcttctcgagcgggagtccgcc caggtagtgaagaagaggaacaccttcctcctgtccatgcggttcatggagcccgagatg gagacgcgctactcggtggagaaggagaagcagagtggggccgccttcagctgctcctgc gtcgtcctgctctgcgcggccgtggccgagatgctcatcgacccctggctaatgacaaac tacgtgacctttgtggttggggaagttctgcttctgatcctgacgatctgctcgctggct gccatctttccccaggcctttcctaagaagctcgtggccttctcaacttggatcgaccgg acccgctgggccaggaacacctgggccatgttagccatcttcattctggttatggcaaat gtcgtggacatgctcagctgcctccagttctacgcgggacccagcaacggcaccgcaggg acggggctggaggacggctgcgcggcgaaccccgagtattacgacgacgtcgccgtgctg tcgctcgtggccaccatcatgctggtgcaggtcagccacatggtgaagctcacgctcatg ctgctcatcgccggcgccgtggccgtcgtcaacatctacgcctggcgccccatctttgac gaatacgaccgcaggcgtttccaggagcacgactttcctgtggttgccttggagaagatg cagatactctccaccgctgggctcaacggcactgacaggctgcccctgctgccctccaag tactcgatgacagcgatgatcttcgtcatgatgctgagcttttactacttctcccgccac gtggaaaaactggctcggacactgttcttatggaagatcgaggtccatgaccagaaggaa cgtgtctacgagatgcggcgctggaacgaggccctggtcaccaacatgttgcctgagcac gtggcgcgccatttcctggggtccaagaagagagacgaggaactgtacagccagtcttat gacgagattggagtcatgtttgcctccctgcccaactttgctgacttctacacagaggag agcatcaataatggtggcattgagtgtctgcgctttctcaacgagatcatctcagacttt gactctctcctggacaatcccaaattccgggtcatcaccaagatcaaaaccattggcagt acctatatggcagcttcaggagtcaccccagatgtcaacaccaatggctttaccagctcc aacaaggaggagaagtccgacaaggagcgctggcagcacctggccgatctggctgacttc gcactagccatgaaggatacgctcaccaacatcaacaaccagtccttcaacaacttcatg ctgcgcataggcatgaacaaaggaggggtactggctggggtcattggagcccggaaacca cattatgacatctggggcaacacagtcaacgtagccagcaggatggagtccacaggggtc atgggcaacattcaggtggtagaagacacacaggccatcctccgagagtatggcttccgc ttcgtgaggcgagggcccatctttgtgaaagggaaaggggagctgctaacctttttcttg aagggccgtgacaagccagccaccttccctaacggctcctctgtcacactgccccaccag gtggtagacaactcctga

Rousettus aegyptiacus (Egyptian rousette): 107502700 Help Entry 107502700         CDS       T06036                                  Symbol ADCY2 Name (RefSeq) adenylate cyclase type 2   KO K08042   adenylate cyclase 2 [EC:4.6.1.1] Organism ray  Rousettus aegyptiacus (Egyptian rousette) Pathway ray00230   Purine metabolism ray01100   Metabolic pathways ray01522   Endocrine resistance ray04015   Rap1 signaling pathway ray04020   Calcium signaling pathway ray04022   cGMP-PKG signaling pathway ray04024   cAMP signaling pathway ray04062   Chemokine signaling pathway ray04072   Phospholipase D signaling pathway ray04081   Hormone signaling ray04082   Neuroactive ligand signaling ray04114   Oocyte meiosis ray04211   Longevity regulating pathway ray04213   Longevity regulating pathway - multiple species ray04261   Adrenergic signaling in cardiomyocytes ray04270   Vascular smooth muscle contraction ray04371   Apelin signaling pathway ray04540   Gap junction ray04611   Platelet activation ray04713   Circadian entrainment ray04714   Thermogenesis ray04723   Retrograde endocannabinoid signaling ray04724   Glutamatergic synapse ray04725   Cholinergic synapse ray04727   GABAergic synapse ray04750   Inflammatory mediator regulation of TRP channels ray04911   Insulin secretion ray04912   GnRH signaling pathway ray04913   Ovarian steroidogenesis ray04914   Progesterone-mediated oocyte maturation ray04915   Estrogen signaling pathway ray04916   Melanogenesis ray04918   Thyroid hormone synthesis ray04921   Oxytocin signaling pathway ray04922   Glucagon signaling pathway ray04923   Regulation of lipolysis in adipocytes ray04925   Aldosterone synthesis and secretion ray04926   Relaxin signaling pathway ray04927   Cortisol synthesis and secretion ray04928   Parathyroid hormone synthesis, secretion and action ray04934   Cushing syndrome ray04935   Growth hormone synthesis, secretion and action ray04970   Salivary secretion ray04971   Gastric acid secretion ray04972   Pancreatic secretion ray04976   Bile secretion ray05032   Morphine addiction ray05163   Human cytomegalovirus infection ray05166   Human T-cell leukemia virus 1 infection ray05200   Pathways in cancer ray05207   Chemical carcinogenesis - receptor activation ray05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:ray00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     107502700 (ADCY2)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     107502700 (ADCY2)    04371 Apelin signaling pathway     107502700 (ADCY2)    04020 Calcium signaling pathway     107502700 (ADCY2)    04072 Phospholipase D signaling pathway     107502700 (ADCY2)    04024 cAMP signaling pathway     107502700 (ADCY2)    04022 cGMP-PKG signaling pathway     107502700 (ADCY2)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     107502700 (ADCY2)    04081 Hormone signaling     107502700 (ADCY2)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     107502700 (ADCY2)   09144 Cellular community - eukaryotes    04540 Gap junction     107502700 (ADCY2)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     107502700 (ADCY2)    04062 Chemokine signaling pathway     107502700 (ADCY2)   09152 Endocrine system    04911 Insulin secretion     107502700 (ADCY2)    04922 Glucagon signaling pathway     107502700 (ADCY2)    04923 Regulation of lipolysis in adipocytes     107502700 (ADCY2)    04912 GnRH signaling pathway     107502700 (ADCY2)    04913 Ovarian steroidogenesis     107502700 (ADCY2)    04915 Estrogen signaling pathway     107502700 (ADCY2)    04914 Progesterone-mediated oocyte maturation     107502700 (ADCY2)    04921 Oxytocin signaling pathway     107502700 (ADCY2)    04926 Relaxin signaling pathway     107502700 (ADCY2)    04935 Growth hormone synthesis, secretion and action     107502700 (ADCY2)    04918 Thyroid hormone synthesis     107502700 (ADCY2)    04928 Parathyroid hormone synthesis, secretion and action     107502700 (ADCY2)    04916 Melanogenesis     107502700 (ADCY2)    04925 Aldosterone synthesis and secretion     107502700 (ADCY2)    04927 Cortisol synthesis and secretion     107502700 (ADCY2)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     107502700 (ADCY2)    04270 Vascular smooth muscle contraction     107502700 (ADCY2)   09154 Digestive system    04970 Salivary secretion     107502700 (ADCY2)    04971 Gastric acid secretion     107502700 (ADCY2)    04972 Pancreatic secretion     107502700 (ADCY2)    04976 Bile secretion     107502700 (ADCY2)   09156 Nervous system    04724 Glutamatergic synapse     107502700 (ADCY2)    04727 GABAergic synapse     107502700 (ADCY2)    04725 Cholinergic synapse     107502700 (ADCY2)    04723 Retrograde endocannabinoid signaling     107502700 (ADCY2)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     107502700 (ADCY2)   09149 Aging    04211 Longevity regulating pathway     107502700 (ADCY2)    04213 Longevity regulating pathway - multiple species     107502700 (ADCY2)   09159 Environmental adaptation    04713 Circadian entrainment     107502700 (ADCY2)    04714 Thermogenesis     107502700 (ADCY2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     107502700 (ADCY2)    05207 Chemical carcinogenesis - receptor activation     107502700 (ADCY2)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     107502700 (ADCY2)    05163 Human cytomegalovirus infection     107502700 (ADCY2)   09165 Substance dependence    05032 Morphine addiction     107502700 (ADCY2)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     107502700 (ADCY2)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     107502700 (ADCY2)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     107502700 (ADCY2) Enzymes [BR:ray01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      107502700 (ADCY2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc Adcy_cons_dom AC_N HNOBA Motif Other DBs NCBI-GeneID:  107502700 NCBI-ProteinID:  XP_015985631 LinkDB All DBs Position Unknown AA seq 1091 aa AA seqDB search MWQEAMRRRRYLRDRAEAAAGGGDGPPRSRDWLYESYYCLSQQHPLIVFLLLIVMGACLA LLVVFFALRLEVEDHVAFLITVPTALAIFFAIFILVCIESVFRKLLRLFSVVIWLCLVAM AHLFMCFGGTVSPWDQVSFFLFVVFVVYTMLPFSMRDAVIASTLTSSSHTIVLSVCLSAT PGAKEHLVWQILANVIIFICGNLAGAYHKHLMELALQQTYQDTCNCIKSRIKLEFEKRQQ ERLLLSLLPAHIAMEMKAEIIQRLQGPKAGHMENTNNFHNLYVKRHTNVSILYADIVGFT RLASDCSPGELVHMLNELFGKFDQIAKENECMRIKILGDCYYCVSGLPISLPNHAKNCVK MGLDMCEAIKKVRDATGVDINMRVGVHSGNVLCGVIGLQKWQYDVWSHDVTLANHMEAGG VPGRVHISSVTLEHLNGAYKVEEGDGDIRDPYLKQHLVKTYFVINPKGERRSPQHLFRPR HTLDGAKMRASVRMTRYLESWGAAKPFAHLHHRDSMTTENGKISTMDVPMGQHNFQNRTL RTKSQKKRFEEELNERMIQAIDGINAQKQWLKSEDIQRISLLFYNKILEKEYRATALPAF KYYVTCACLIFFCIFVVQILVLPKTSALGISFGAASLSLAFILFVCFAGQLLQCSKKASA SLLWLLKSSGVIANRPWPQISLTVITTAIVLTMAVLNMFFLSDPEEAVPPATNTSNASLS ASHRQAAILRAQNLFFLPYFIYSCILGLISCSVFLRVNYELKMSIMTAALVGYNTVFLHT HAHVLDSYSQVLFERPGIWKDLKTMGSVSLSIFFVTLLVLGRQNEYYCRLDFLWKNKFKK EREEIETMENLNRVLLENVLPAHVAEHFLARSLKNEDLYHQSYACVCVMFASIPDFKEFY TESDVNKEGLECLRLLNEIIADFDDLLSKPKFSGVEKIKTIGSTYMAATGLSAVPSQEHA QEPERQYTHIGTMVEFAFALGAKLTAINKHSFNDFKLRVGMNHGPVIAGVIGAQKPQYDI WGNTVNVASRMDSTGVLDKIQVTEETSLILQTLGYTCTCRGIINVKGKGELKTYFVSTEM SGSLSQSNLAA NT seq 3276 nt NT seq  +upstreamnt  +downstreamnt atgtggcaggaggcgatgcggcgccgccgctacctgcgggaccgcgccgaggcggcggcg ggcggcggcgacgggccgccgcggtcccgcgactggctgtacgagtcctactactgcctg agccagcagcacccgctcatcgtcttcctgctgctcatcgtcatgggcgcctgcctcgcg ctgctcgtcgtcttcttcgcgctgcggctggaagtcgaagaccacgtggcatttttaatc acggtccccaccgccctggccatcttcttcgcgatcttcatcctcgtgtgcatcgagtcc gtgttcaggaagctgctccgcctcttctccgtggtcatctggctgtgcctggtcgccatg gcgcacctgttcatgtgcttcgggggcaccgtctctccctgggaccaggtgtccttcttc ctcttcgtcgtcttcgtggtgtacaccatgctgcccttcagcatgcgggacgccgtcatc gccagcacgctcacctcatcctcccacaccatcgtgctgagcgtctgcctgtctgcaacg cccggggccaaggagcacctggtctggcagatcctggccaacgtgatcatcttcatctgc gggaacctggcgggcgcgtaccacaagcacctcatggagctcgccctgcagcagacctat caggacacctgcaactgcatcaagtcccggatcaagctggaattcgagaagcggcagcag gagcggcttctgctctccctgctgccggcccacatagccatggagatgaaggccgagatc atccagcggctccagggccccaaagccggccacatggaaaacacgaacaacttccacaac ctgtacgtcaagcgacacaccaacgtcagtatcctgtacgccgacattgtggggttcact cggctggccagtgactgctccccaggagagctggtccacatgctgaatgaactctttggg aaattcgatcaaattgcgaaggagaacgaatgcatgaggataaaaattttaggcgactgc tactactgcgtgtccggactcccgatctccctccctaaccatgccaagaactgcgtgaaa atggggctggacatgtgtgaagccataaagaaagtgagggacgcgacgggggtcgacatc aacatgcgcgtgggggtgcactcggggaacgtcctgtgcggcgtgatcggcctgcagaag tggcagtacgacgtgtggtcccacgacgtcaccttggccaaccacatggaagccggcggg gtccccggacgtgtccacatttcgtctgtcaccctggagcacctgaatggggcttataaa gtggaggaaggggacggtgacatcagggacccatacttaaagcagcacctggtgaaaacc tacttcgtaatcaaccccaagggagagcgacggagcccgcagcacctgttcagacctcgc cacacgctcgacggggccaagatgagggcgtccgtgcgcatgacgcggtacctggagtcg tggggggccgccaagcccttcgcccacctgcaccaccgggacagcatgaccacggagaac ggcaagatcagcaccatggatgtgccgatgggtcagcataattttcaaaaccgcacctta agaaccaagtcacaaaagaaaaggtttgaagaagaattgaatgaaaggatgattcaagca attgatggaattaatgcacaaaagcaatggctcaagtctgaagacattcaaagaatctca ctgcttttctacaataaaatactagaaaaagagtaccgagccacggcgctgcccgccttc aagtactacgtgacctgcgcgtgcctcattttcttctgcatcttcgtcgtgcagattctc gtgttgccgaagacgtccgctctcggcatctccttcggggccgcgtccctctcgctcgcc ttcatcctgttcgtctgcttcgccggacagctcctgcaatgcagcaaaaaggcctctgcc tccctcctgtggctgttgaagtcgtcgggtgtcatcgcgaaccgcccgtggccgcagatc tcgctcacggtcatcaccacggcgatcgtcctaaccatggccgtcctcaacatgtttttc ctgagcgacccagaggaagccgtcccccccgccaccaacacgtcgaacgcgagcctctct gcctcgcaccgccaggcggccatcctgcgcgcgcagaacctgtttttcctcccgtacttc atctacagctgcattctggggctgatatcctgctccgtgttcctgcgggtgaactacgag ctgaaaatgtccatcatgacggcagcgctggtgggctacaacaccgtcttcctccacacc cacgcccacgtcctggacagctacagccaggtcctgtttgagagaccaggcatttggaaa gacttaaagaccatgggctcggtgtccctctccatcttcttcgtcacactgctcgttctg ggcagacagaatgaatattactgtaggttagacttcttgtggaagaacaagttcaaaaaa gagcgggaggagatagagaccatggagaacctgaaccgcgtgctgctggagaacgtgctc cccgcccacgtggccgagcacttcctggccaggagcctgaagaacgaggacttgtaccac cagtcctacgcctgcgtctgcgtgatgttcgcctccatcccggacttcaaggagttctac accgagtcggacgttaacaaggagggcttggagtgcctgcggctcctcaacgagatcatc gccgacttcgacgacctgctgtccaagccgaaattcagcggggtggaaaagatcaagacc atcgggagcacgtacatggccgccacgggcctgagcgccgtgcccagccaggagcacgcc caggagcccgagcgccagtacacgcacatcggcaccatggtggagttcgccttcgcgctg ggggccaagctgaccgccatcaacaagcactccttcaatgacttcaagctgcgcgtgggc atgaaccacggccccgtgatcgccggcgtgatcggcgcccagaagccgcagtacgacatc tggggcaacaccgtcaacgtggccagcaggatggacagcaccggggtcctggacaagatt caggtcacggaggagaccagcctcatcctgcagacgctggggtacacgtgcacgtgccgg ggcatcatcaacgtgaagggcaagggggagctgaagacctacttcgtgagcacggaaatg tccggctccctctcccagagcaacctggccgcctga

Rousettus aegyptiacus (Egyptian rousette): 107512248 Help Entry 107512248         CDS       T06036                                  Symbol ADCY7 Name (RefSeq) adenylate cyclase type 7 isoform X1   KO K08047   adenylate cyclase 7 [EC:4.6.1.1] Organism ray  Rousettus aegyptiacus (Egyptian rousette) Pathway ray00230   Purine metabolism ray01100   Metabolic pathways ray01522   Endocrine resistance ray04015   Rap1 signaling pathway ray04020   Calcium signaling pathway ray04022   cGMP-PKG signaling pathway ray04024   cAMP signaling pathway ray04062   Chemokine signaling pathway ray04072   Phospholipase D signaling pathway ray04081   Hormone signaling ray04082   Neuroactive ligand signaling ray04114   Oocyte meiosis ray04211   Longevity regulating pathway ray04213   Longevity regulating pathway - multiple species ray04261   Adrenergic signaling in cardiomyocytes ray04270   Vascular smooth muscle contraction ray04371   Apelin signaling pathway ray04540   Gap junction ray04611   Platelet activation ray04713   Circadian entrainment ray04714   Thermogenesis ray04723   Retrograde endocannabinoid signaling ray04724   Glutamatergic synapse ray04725   Cholinergic synapse ray04727   GABAergic synapse ray04750   Inflammatory mediator regulation of TRP channels ray04911   Insulin secretion ray04912   GnRH signaling pathway ray04913   Ovarian steroidogenesis ray04914   Progesterone-mediated oocyte maturation ray04915   Estrogen signaling pathway ray04916   Melanogenesis ray04918   Thyroid hormone synthesis ray04921   Oxytocin signaling pathway ray04923   Regulation of lipolysis in adipocytes ray04925   Aldosterone synthesis and secretion ray04926   Relaxin signaling pathway ray04927   Cortisol synthesis and secretion ray04928   Parathyroid hormone synthesis, secretion and action ray04934   Cushing syndrome ray04935   Growth hormone synthesis, secretion and action ray04970   Salivary secretion ray04971   Gastric acid secretion ray04972   Pancreatic secretion ray04976   Bile secretion ray05032   Morphine addiction ray05163   Human cytomegalovirus infection ray05166   Human T-cell leukemia virus 1 infection ray05200   Pathways in cancer ray05207   Chemical carcinogenesis - receptor activation ray05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:ray00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     107512248 (ADCY7)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     107512248 (ADCY7)    04371 Apelin signaling pathway     107512248 (ADCY7)    04020 Calcium signaling pathway     107512248 (ADCY7)    04072 Phospholipase D signaling pathway     107512248 (ADCY7)    04024 cAMP signaling pathway     107512248 (ADCY7)    04022 cGMP-PKG signaling pathway     107512248 (ADCY7)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     107512248 (ADCY7)    04081 Hormone signaling     107512248 (ADCY7)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     107512248 (ADCY7)   09144 Cellular community - eukaryotes    04540 Gap junction     107512248 (ADCY7)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     107512248 (ADCY7)    04062 Chemokine signaling pathway     107512248 (ADCY7)   09152 Endocrine system    04911 Insulin secretion     107512248 (ADCY7)    04923 Regulation of lipolysis in adipocytes     107512248 (ADCY7)    04912 GnRH signaling pathway     107512248 (ADCY7)    04913 Ovarian steroidogenesis     107512248 (ADCY7)    04915 Estrogen signaling pathway     107512248 (ADCY7)    04914 Progesterone-mediated oocyte maturation     107512248 (ADCY7)    04921 Oxytocin signaling pathway     107512248 (ADCY7)    04926 Relaxin signaling pathway     107512248 (ADCY7)    04935 Growth hormone synthesis, secretion and action     107512248 (ADCY7)    04918 Thyroid hormone synthesis     107512248 (ADCY7)    04928 Parathyroid hormone synthesis, secretion and action     107512248 (ADCY7)    04916 Melanogenesis     107512248 (ADCY7)    04925 Aldosterone synthesis and secretion     107512248 (ADCY7)    04927 Cortisol synthesis and secretion     107512248 (ADCY7)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     107512248 (ADCY7)    04270 Vascular smooth muscle contraction     107512248 (ADCY7)   09154 Digestive system    04970 Salivary secretion     107512248 (ADCY7)    04971 Gastric acid secretion     107512248 (ADCY7)    04972 Pancreatic secretion     107512248 (ADCY7)    04976 Bile secretion     107512248 (ADCY7)   09156 Nervous system    04724 Glutamatergic synapse     107512248 (ADCY7)    04727 GABAergic synapse     107512248 (ADCY7)    04725 Cholinergic synapse     107512248 (ADCY7)    04723 Retrograde endocannabinoid signaling     107512248 (ADCY7)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     107512248 (ADCY7)   09149 Aging    04211 Longevity regulating pathway     107512248 (ADCY7)    04213 Longevity regulating pathway - multiple species     107512248 (ADCY7)   09159 Environmental adaptation    04713 Circadian entrainment     107512248 (ADCY7)    04714 Thermogenesis     107512248 (ADCY7)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     107512248 (ADCY7)    05207 Chemical carcinogenesis - receptor activation     107512248 (ADCY7)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     107512248 (ADCY7)    05163 Human cytomegalovirus infection     107512248 (ADCY7)   09165 Substance dependence    05032 Morphine addiction     107512248 (ADCY7)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     107512248 (ADCY7)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     107512248 (ADCY7)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     107512248 (ADCY7) Enzymes [BR:ray01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      107512248 (ADCY7) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc Adcy_cons_dom AC_N Motif Other DBs NCBI-GeneID:  107512248 NCBI-ProteinID:  XP_016003077 LinkDB All DBs Position Unknown AA seq 1078 aa AA seqDB search MPAKGRYFLNEGEEGPGHDVLYEKYRLTSQHGPLLRTLLLVAVAACTALAAIAFGSGDPS RHKAVLGTALVTLVVFVALYVLVYIECLVRRWLSAAALLTWACLVTLGYVLVFDSWTNAA CAWEQLPFFLFVVFVVYTLLPFSTRGAVAAGVVSSASHLLVLGTLTGVFSKPSTRMGLQL LANAAVFLCGNLMGAFHKHQMQDASRELFTYAVKCIQIRRKLRVEKRQQENLLLSVLPAH ISMGMKLTIIERLKERGDRRYLPDNNFHSLYVKRHQNVSILYADIVGFTRLASDCSPKEL VVMLNELFGKFDQIAKANECMRIKILGDCYYCVSGLPVSLPTHARNCVKMGLDICEAIKQ VREATGVDISMRVGIHSGNVLCGVIGLRKWQYDVWSHDVSLANRMEAAGVPGRVHITEAT LSHLDKAYEVEDGHGQQRDSYLKEMNIRTYLVIDPRSQQPPPPVQHLPKPRGEATLKMRA SVRMTRYLESWGAARPFAHLSHRESLSSGGTPVPPGRRPKAIPLRRHRTPDRSASPKGRS EDDSYDDEMLSAIEGLSSARPCCSKSDDFYTFGSIFLEKGFEREYRLAPIPRARHYFACA SLVFLCILLVHVLLMPRTAALGVSFGLVACVLGLVLGLCFADELLRCCPARGTPRSISER VETHPLLRLSLAILTVGSLLTIAIVNLPLLPSPALGPPAGNESSPSALRGGDGTPCELLQ YYTCSCVLAFVACSVFLRMSLELKVVLLTVALVAYLVLFSVSLCSRWHCCDSPGNLTNGT DTLSPSVCSWRDLKTMICFYLVLFYTTLIMLSRQIDYYCRLDCLWKNKFKKEHEEFETME NVNRLLLENVLPAHVAAHFIGDKLNEDWYHQSYDCVSVMFASVPDFKVFYTECDVNKEGL ECLRLLNEIIADFDELLLKPKFSSVEKIKTIGSTYMAAAGLSVPSGHENQDLERRHAHVG IAVDFSAALMSKLDGINRHSFNSFRLRVGINHGPVIAGVIGARKPQYDIWGNTVNVASRM ESTGELGKIQVTEETCTILRGLGYSCECRGLINVKGKGELRTYFVCTDAGKFQGLGLN NT seq 3237 nt NT seq  +upstreamnt  +downstreamnt atgccggccaagggacgctacttcctcaacgagggcgaggagggcccgggccacgacgtg ctctacgagaagtaccgcctcaccagccagcacgggccgctgctgcgcacgctcctgctg gtggccgtggccgcctgcaccgccctcgccgccatcgccttcggctccggggatccctcc agacacaaggctgtgctggggacggcgctcgtgacgctcgtcgtgttcgtggccctctac gtgctggtgtacatcgagtgcctcgtccgtcgctggctctcggccgccgcgctgctcacc tgggcctgcctcgtgacgctgggctacgtgctggtgttcgactcatggacgaacgcagcc tgcgcgtgggagcagctgcccttcttcctgttcgtggtcttcgtggtgtacacgctcctg cccttcagcacgcggggggccgtggccgcgggcgtcgtctccagcgcctcccacctgctg gtgctgggcaccctgacgggcgtcttctccaagcccagcacccggatggggctgcagctg ctggccaacgccgccgtcttcctgtgcgggaacctcatgggcgccttccacaagcaccag atgcaggacgcgtcccgcgagctcttcacctacgcggtcaagtgcatccagatccgcagg aagctgcgcgtcgagaagcggcagcaggagaacctgctcctgtcggtgctgccggcccac atctccatgggcatgaagctgaccatcatcgagcggctcaaggagcgtggggaccgccgc tacctgcccgacaacaacttccacagcctctacgtcaagcggcaccagaatgtcagcatc ctctacgcggacatcgtgggcttcacgcggctggccagcgactgctcccccaaagagctg gtggtgatgctcaatgagctcttcggcaagttcgaccagatcgcgaaggccaacgagtgc atgcggatcaagatcctgggcgactgctactactgcgtgtcgggcctgcccgtgtccctg cccacccacgcccgcaactgcgtgaagatggggctggacatctgcgaggccatcaagcag gtgcgggaggccacgggcgtggacatcagcatgcgtgtgggcatccactccgggaacgtg ctgtgcggtgtcatcggcctgcgcaagtggcagtacgatgtgtggtcccatgacgtgtcc ctcgccaacaggatggaggcggccggcgtccctggccgagtgcacatcacggaggcgacg ctgagccacctggacaaggcgtacgaggtggaggacgggcatggccagcagcgcgactcc tacctgaaggagatgaacatccgcacgtacctggtcatcgacccccggagccagcagccg ccgccgccggtgcagcacctccccaagcccaggggggaggcgaccctgaagatgcgggcg tccgtgcgcatgacccgctacctcgagtcctggggcgccgctcggcccttcgcccacctc agccaccgcgagagcctgagcagcggcggaacgcccgtgccccccggccggcggcccaag gccatccccctgcggcgccaccggacccctgacagaagcgcatccccaaaggggcggtcc gaagatgactcgtatgacgacgagatgctgtcggccatcgagggcctcagctctgccagg ccctgctgctccaagtctgacgacttttacacttttgggtccatcttcctggagaagggc tttgagcgagagtaccgcctggcgcccatcccccgggcccggcactacttcgcctgcgcc agcctcgtcttcctctgcatcctgctcgtccacgtgctgctgatgcccaggacggcggcc ctgggggtgtcctttgggctggtggcctgtgtgctgggcttggtcctgggcctgtgcttt gctgacgagctcctgaggtgctgccccgcccgggggacgccccggtccatctccgagagg gtggagacgcaccccctgctgcggctgtccctggccatcctgaccgtcggcagcctgctc accatcgccatcgtcaacctgccactgttgccttcgccagccctggggccccctgctggg aacgagagcagcccgagcgccctccgcggtggggacgggaccccgtgcgagctcctccag tattacacctgcagctgcgtcctggccttcgtcgcctgttctgtcttcctgcgaatgagc ctggagctgaaggtcgtgttgctgaccgtggccttggtggcctacctggtgctcttcagc gtctccctgtgctcgcggtggcactgctgtgacagcccgggcaacctcaccaacggcacc gacaccctcagcccctcggtctgctcgtggagggacctgaagaccatgatctgcttctac ctggttctgttctacaccacgctcatcatgctctccaggcagatcgattactactgccgc ctggactgtctgtggaagaacaagttcaagaaggagcacgaggagttcgagaccatggag aacgtgaaccgcctcctcctggagaacgtcctgccggcccacgtggctgcccacttcatt ggcgacaagttgaatgaggactggtaccatcagtcctacgactgtgtctccgtcatgttt gcgtccgtgccggacttcaaggtcttctacacggagtgcgacgtcaacaaggagggcctg gagtgcctgcgcctgctcaacgagatcatcgccgacttcgacgagctgctgctcaagccc aagttcagcagcgtggagaagatcaagaccatcggcagcacctacatggcggccgccggg ctcagcgtcccctcagggcacgagaaccaggacctggagcggcggcacgcccacgtgggc atcgcggtggacttcagcgcggccctcatgagcaagctggacggcatcaacaggcactcc ttcaactccttccgcctccgcgtcggcataaaccacgggcccgtgatcgcgggcgtgatc ggggcgcggaagcctcagtacgacatctgggggaacacggtcaacgtcgccagcaggatg gagagcactggagagctcgggaaaatccaggtgacggaggagacgtgcaccattctccgg ggactgggttattcctgcgagtgccgcgggctgatcaatgtcaagggcaaaggtgaactg aggacctactttgtctgcacagacgctggcaagtttcaggggctggggctgaactga

Rousettus aegyptiacus (Egyptian rousette): 107512406 Help Entry 107512406         CDS       T06036                                  Symbol ADCY1 Name (RefSeq) adenylate cyclase type 1 isoform X1   KO K08041   adenylate cyclase 1 [EC:4.6.1.1] Organism ray  Rousettus aegyptiacus (Egyptian rousette) Pathway ray00230   Purine metabolism ray01100   Metabolic pathways ray01522   Endocrine resistance ray04015   Rap1 signaling pathway ray04020   Calcium signaling pathway ray04022   cGMP-PKG signaling pathway ray04024   cAMP signaling pathway ray04062   Chemokine signaling pathway ray04072   Phospholipase D signaling pathway ray04081   Hormone signaling ray04082   Neuroactive ligand signaling ray04114   Oocyte meiosis ray04211   Longevity regulating pathway ray04213   Longevity regulating pathway - multiple species ray04261   Adrenergic signaling in cardiomyocytes ray04270   Vascular smooth muscle contraction ray04371   Apelin signaling pathway ray04540   Gap junction ray04611   Platelet activation ray04713   Circadian entrainment ray04714   Thermogenesis ray04720   Long-term potentiation ray04723   Retrograde endocannabinoid signaling ray04724   Glutamatergic synapse ray04725   Cholinergic synapse ray04727   GABAergic synapse ray04750   Inflammatory mediator regulation of TRP channels ray04911   Insulin secretion ray04912   GnRH signaling pathway ray04913   Ovarian steroidogenesis ray04914   Progesterone-mediated oocyte maturation ray04915   Estrogen signaling pathway ray04916   Melanogenesis ray04918   Thyroid hormone synthesis ray04921   Oxytocin signaling pathway ray04923   Regulation of lipolysis in adipocytes ray04925   Aldosterone synthesis and secretion ray04926   Relaxin signaling pathway ray04927   Cortisol synthesis and secretion ray04928   Parathyroid hormone synthesis, secretion and action ray04934   Cushing syndrome ray04935   Growth hormone synthesis, secretion and action ray04970   Salivary secretion ray04971   Gastric acid secretion ray04972   Pancreatic secretion ray04976   Bile secretion ray05032   Morphine addiction ray05142   Chagas disease ray05146   Amoebiasis ray05163   Human cytomegalovirus infection ray05166   Human T-cell leukemia virus 1 infection ray05200   Pathways in cancer ray05207   Chemical carcinogenesis - receptor activation ray05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:ray00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     107512406 (ADCY1)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     107512406 (ADCY1)    04371 Apelin signaling pathway     107512406 (ADCY1)    04020 Calcium signaling pathway     107512406 (ADCY1)    04072 Phospholipase D signaling pathway     107512406 (ADCY1)    04024 cAMP signaling pathway     107512406 (ADCY1)    04022 cGMP-PKG signaling pathway     107512406 (ADCY1)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     107512406 (ADCY1)    04081 Hormone signaling     107512406 (ADCY1)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     107512406 (ADCY1)   09144 Cellular community - eukaryotes    04540 Gap junction     107512406 (ADCY1)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     107512406 (ADCY1)    04062 Chemokine signaling pathway     107512406 (ADCY1)   09152 Endocrine system    04911 Insulin secretion     107512406 (ADCY1)    04923 Regulation of lipolysis in adipocytes     107512406 (ADCY1)    04912 GnRH signaling pathway     107512406 (ADCY1)    04913 Ovarian steroidogenesis     107512406 (ADCY1)    04915 Estrogen signaling pathway     107512406 (ADCY1)    04914 Progesterone-mediated oocyte maturation     107512406 (ADCY1)    04921 Oxytocin signaling pathway     107512406 (ADCY1)    04926 Relaxin signaling pathway     107512406 (ADCY1)    04935 Growth hormone synthesis, secretion and action     107512406 (ADCY1)    04918 Thyroid hormone synthesis     107512406 (ADCY1)    04928 Parathyroid hormone synthesis, secretion and action     107512406 (ADCY1)    04916 Melanogenesis     107512406 (ADCY1)    04925 Aldosterone synthesis and secretion     107512406 (ADCY1)    04927 Cortisol synthesis and secretion     107512406 (ADCY1)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     107512406 (ADCY1)    04270 Vascular smooth muscle contraction     107512406 (ADCY1)   09154 Digestive system    04970 Salivary secretion     107512406 (ADCY1)    04971 Gastric acid secretion     107512406 (ADCY1)    04972 Pancreatic secretion     107512406 (ADCY1)    04976 Bile secretion     107512406 (ADCY1)   09156 Nervous system    04724 Glutamatergic synapse     107512406 (ADCY1)    04727 GABAergic synapse     107512406 (ADCY1)    04725 Cholinergic synapse     107512406 (ADCY1)    04720 Long-term potentiation     107512406 (ADCY1)    04723 Retrograde endocannabinoid signaling     107512406 (ADCY1)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     107512406 (ADCY1)   09149 Aging    04211 Longevity regulating pathway     107512406 (ADCY1)    04213 Longevity regulating pathway - multiple species     107512406 (ADCY1)   09159 Environmental adaptation    04713 Circadian entrainment     107512406 (ADCY1)    04714 Thermogenesis     107512406 (ADCY1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     107512406 (ADCY1)    05207 Chemical carcinogenesis - receptor activation     107512406 (ADCY1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     107512406 (ADCY1)    05163 Human cytomegalovirus infection     107512406 (ADCY1)   09174 Infectious disease: parasitic    05146 Amoebiasis     107512406 (ADCY1)    05142 Chagas disease     107512406 (ADCY1)   09165 Substance dependence    05032 Morphine addiction     107512406 (ADCY1)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     107512406 (ADCY1)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     107512406 (ADCY1)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     107512406 (ADCY1) Enzymes [BR:ray01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      107512406 (ADCY1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N Adcy_cons_dom Motif Other DBs NCBI-GeneID:  107512406 NCBI-ProteinID:  XP_016003382 LinkDB All DBs Position Unknown AA seq 1132 aa AA seqDB search MAGAPRGRGGGGGGGGGGGGGGAGEPGGAERAAAPGGRRGLRACDEEFACPELEALFRGY TLRLEQAATLKALAVLSLLAGALALAELLGAPGPAPGLARGSHPVHCALFLALLVVTNVR SLQVPQLQHVGQLALLFSLTFALLCCPFALGGPAGLRAAAAAGPAAADQGVWQLLLVTFV SYALLPVRSLLAVGFGLVVAASHLLVTATLVPAKRPRLWRTLGANALLFVGVNMYGVFVR VLAERSQRRAFLQARSCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFH KIYIQRHDNVSILFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCRRIKILGD CYYCVSGLTQPKADHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLR KWQYDVWSNDVTLANVMEAAGLPGKVHITKTTLTCLNGDYEVEPGHGHERNSFLRTHNIE TFFIVPSHRRKIFPGLILSDIKPAKRMRFRTVCYLLVQLMHCRRVFKAEVPFSNVMTCED DDKRRALRTASEKLRNRSSFSTNVVHAAPGTRVNRYIGRLLEARQTDLEMADLNFFTLKY KQAEREHKYHQLQDEHFGSAVVLALVLAALFGLVYLLVIPQSLAVLLLLVFCICFLVACV LYLHITRVQCFPGCLTIRIRTVLCIFIVVLIYAVAQACVVGCLPWAWSASANGSLVVLSP GGRGPVLPAAPCESAPHALLCGLVGTLPLTLFLRVSSLPKVILLSVLTASYILVLELGGY TRAAGGGPVPGGSFEPVVAVLLFSCTLALHARQVDIKLRLDYLWAAQAEEERDDMERVKL DNKRILFNLLPAHVAQHFLTSNPRSMDLYYQSYSQVGVMFASIPNFNDFYIELDGNNMGV ECLRLLNEIIADFDELMEKDFYKDLEKIKTIGSTYMAAVGLVPVAGAKAKKCISAHLSTL ADFAIEMFDVLDEINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDS TGVPGRIQVTEEVHRLLRQGAYRFLCRGKVSVKGKGEMLTYFLEGRTDGNGPQTRPLSSE RRTFPYGRAGLQTGLATGCPRVGAGPGALQGSGLAPRPPGPHLPPAASGKEA NT seq 3399 nt NT seq  +upstreamnt  +downstreamnt atggcgggggcgccgcgcggccgaggcggaggcggaggcggaggcggcggcggcggcggc ggcggcgcgggcgagcccgggggcgccgagcgggctgccgccccgggcggccggcgcggg ctgcgggcgtgcgacgaggagttcgcgtgccccgagctggaggcgctgttccgcggctac acgctgcggctggagcaggcggccacgctgaaggcgctggccgtgctcagcctgctggcg ggcgcgctggcgctggccgagctgctgggcgcgccggggcccgcgccgggcctggccagg ggctcgcaccccgtgcactgcgcgctcttcctggcgctgctcgtggtcaccaatgtccgc tcgctgcaggtgccgcagctgcagcacgtgggccagctcgcgctgctcttcagcctcacc ttcgcgctgctctgctgccccttcgcgctcggcggccccgccgggctccgcgccgcggcc gccgcggggccagcggccgccgaccagggcgtctggcagctcctgctggtcaccttcgtg tcttacgccctgctgcccgtgcgcagcctgctggccgtcggcttcgggctcgtggtggcc gcctcgcacttgctggtcacggccaccttggtccccgccaagcgtccacgtctctggagg acgctcggcgccaacgccctgctcttcgtgggcgtgaacatgtacggcgtcttcgtgagg gtcctggccgagcgctcccagcggagggcctttctgcaggcccggagctgcatcgaggac cggctgcggctggaggacgagaacgagaagcaggagcggctgctcatgagcctcctgccc cggaatgttgccatggagatgaaggaggacttcctgaagcctccggagaggattttccac aagatttacatccagcggcatgacaacgtgagcatcctcttcgcggacatcgtgggcttc acgggcctggcatcgcagtgcacggcgcaggagctggtgaagctgctgaacgagctcttc ggcaagtttgacgagctggccacggagaaccactgccgccgcatcaagatcctgggggac tgctactactgcgtgtccggcctcacccagcccaaggccgaccacgcgcactgctgcgtg gagatgggcctggacatgatcgacaccatcacgtccgtggccgaggccaccgaggtggac ctgaacatgcgcgtggggctgcacaccggccgcgtcctctgcggggtcctgggcctgcgc aagtggcagtatgacgtgtggtccaacgacgtgactttggccaacgtcatggaggccgcc ggcctgcccggcaaggttcacatcaccaagaccacgctgacctgcctgaacggcgactac gaggtggagccgggccacgggcacgagaggaacagctttctgaggacacacaacatcgag accttcttcattgtgccctcacatcggcggaagatattcccagggctgatcctgtcggac atcaagccggccaagcggatgaggttccggacggtgtgctacctgctggtgcagctcatg cactgccggcgggtgttcaaggccgaggtccccttctccaacgtcatgacctgtgaggac gacgacaagcgcagggcgttgaggacggcctccgagaagctcagaaaccgctcgtctttc tccacaaacgttgtgcacgccgccccaggcacccgcgtcaacaggtacatcggccgcctc ctggaagcccgccagacggacctggagatggccgacctcaacttcttcacgctgaagtac aagcaggccgagcgggagcacaagtaccaccagctgcaggacgagcacttcggcagcgcc gtggtgctcgcgctcgtgctggccgccttgttcggcctcgtctacctcctggtcatcccg cagagtctggccgtcctgctcctgctggtgttctgcatctgcttcctggtggcctgcgtc ctgtacctgcatatcacccgggtccagtgcttcccggggtgcctgaccatccggatccgc accgtgctgtgcattttcatcgtggtcctgatctatgccgtggcccaggcgtgcgtggtg ggctgcctgccctgggcctggagcgccagtgccaacgggtccctggtggtcctgtcgccc ggcggccgcggcccagtgctgccggccgcgccctgcgagtcggcgccgcacgccctgctc tgcggcctggtgggcacgctgccgctcaccctgttcctgcgcgtctcctccttgccgaag gtcatcctgctgtccgtgctcaccgcgtcctacatcctggtcctggagctcggcggctac accagggccgcggggggcggccccgtgcctgggggcagcttcgagccggtggtggccgtc ctgctgttctcatgcaccctggccctgcatgcccgccaggtggacatcaagctgcggctg gactacctgtgggctgcgcaggctgaggaggagcgggacgacatggagcgggtcaagctg gacaacaagaggattctgttcaacctgctgccggcccacgtggcccagcactttctcacg tccaacccccggagcatggacctctactaccagtcgtactcgcaggtgggcgtcatgttt gcctccatccccaacttcaatgacttctacatcgagctggatggcaacaacatgggggtg gagtgcctgcgcctcctgaacgagatcatcgctgactttgacgagctcatggagaaggac ttctacaaggacctggaaaagatcaagaccatcgggagcacctacatggccgcggtgggg ctggtgcccgtggctggggccaaggctaagaagtgcatctccgcccacctcagcacgctg gcggacttcgccatcgagatgtttgacgtcctggacgagatcaactaccagtcgtacaat gactttgtgctccgcgtgggcatcaacgtgggccctgtggtggccggagtgatcggggct cgccggccgcagtacgacatctggggaaacacggtcaacgtggccagtcggatggacagc actggggttccgggcagaatccaggtgacggaggaggtgcaccggctgctgaggcagggc gcctaccgcttcttgtgccgcggcaaggtcagcgtcaagggcaagggcgagatgctcacc tacttcctggaaggcaggaccgatgggaacggcccccagaccaggcccctgagctcggag cggagaacgtttccgtatgggagagccggcctccagaccggactggccacaggctgcccc cgggtcggagccgggccgggtgcgctgcagggctcggggctcgctcctcggccccctggc ccacacctgccgccggcagcctccggcaaggaggcttag

Rousettus aegyptiacus (Egyptian rousette): 107514224 Help Entry 107514224         CDS       T06036                                  Symbol ADCY6 Name (RefSeq) adenylate cyclase type 6 isoform X1   KO K08046   adenylate cyclase 6 [EC:4.6.1.1] Organism ray  Rousettus aegyptiacus (Egyptian rousette) Pathway ray00230   Purine metabolism ray01100   Metabolic pathways ray01522   Endocrine resistance ray04015   Rap1 signaling pathway ray04022   cGMP-PKG signaling pathway ray04024   cAMP signaling pathway ray04062   Chemokine signaling pathway ray04072   Phospholipase D signaling pathway ray04081   Hormone signaling ray04082   Neuroactive ligand signaling ray04114   Oocyte meiosis ray04211   Longevity regulating pathway ray04213   Longevity regulating pathway - multiple species ray04261   Adrenergic signaling in cardiomyocytes ray04270   Vascular smooth muscle contraction ray04371   Apelin signaling pathway ray04540   Gap junction ray04611   Platelet activation ray04713   Circadian entrainment ray04714   Thermogenesis ray04723   Retrograde endocannabinoid signaling ray04724   Glutamatergic synapse ray04725   Cholinergic synapse ray04727   GABAergic synapse ray04742   Taste transduction ray04750   Inflammatory mediator regulation of TRP channels ray04911   Insulin secretion ray04912   GnRH signaling pathway ray04913   Ovarian steroidogenesis ray04914   Progesterone-mediated oocyte maturation ray04915   Estrogen signaling pathway ray04916   Melanogenesis ray04918   Thyroid hormone synthesis ray04921   Oxytocin signaling pathway ray04923   Regulation of lipolysis in adipocytes ray04924   Renin secretion ray04925   Aldosterone synthesis and secretion ray04926   Relaxin signaling pathway ray04927   Cortisol synthesis and secretion ray04928   Parathyroid hormone synthesis, secretion and action ray04934   Cushing syndrome ray04935   Growth hormone synthesis, secretion and action ray04961   Endocrine and other factor-regulated calcium reabsorption ray04962   Vasopressin-regulated water reabsorption ray04970   Salivary secretion ray04971   Gastric acid secretion ray04972   Pancreatic secretion ray04976   Bile secretion ray05032   Morphine addiction ray05163   Human cytomegalovirus infection ray05166   Human T-cell leukemia virus 1 infection ray05200   Pathways in cancer ray05207   Chemical carcinogenesis - receptor activation ray05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:ray00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     107514224 (ADCY6)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     107514224 (ADCY6)    04371 Apelin signaling pathway     107514224 (ADCY6)    04072 Phospholipase D signaling pathway     107514224 (ADCY6)    04024 cAMP signaling pathway     107514224 (ADCY6)    04022 cGMP-PKG signaling pathway     107514224 (ADCY6)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     107514224 (ADCY6)    04081 Hormone signaling     107514224 (ADCY6)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     107514224 (ADCY6)   09144 Cellular community - eukaryotes    04540 Gap junction     107514224 (ADCY6)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     107514224 (ADCY6)    04062 Chemokine signaling pathway     107514224 (ADCY6)   09152 Endocrine system    04911 Insulin secretion     107514224 (ADCY6)    04923 Regulation of lipolysis in adipocytes     107514224 (ADCY6)    04912 GnRH signaling pathway     107514224 (ADCY6)    04913 Ovarian steroidogenesis     107514224 (ADCY6)    04915 Estrogen signaling pathway     107514224 (ADCY6)    04914 Progesterone-mediated oocyte maturation     107514224 (ADCY6)    04921 Oxytocin signaling pathway     107514224 (ADCY6)    04926 Relaxin signaling pathway     107514224 (ADCY6)    04935 Growth hormone synthesis, secretion and action     107514224 (ADCY6)    04918 Thyroid hormone synthesis     107514224 (ADCY6)    04928 Parathyroid hormone synthesis, secretion and action     107514224 (ADCY6)    04916 Melanogenesis     107514224 (ADCY6)    04924 Renin secretion     107514224 (ADCY6)    04925 Aldosterone synthesis and secretion     107514224 (ADCY6)    04927 Cortisol synthesis and secretion     107514224 (ADCY6)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     107514224 (ADCY6)    04270 Vascular smooth muscle contraction     107514224 (ADCY6)   09154 Digestive system    04970 Salivary secretion     107514224 (ADCY6)    04971 Gastric acid secretion     107514224 (ADCY6)    04972 Pancreatic secretion     107514224 (ADCY6)    04976 Bile secretion     107514224 (ADCY6)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     107514224 (ADCY6)    04961 Endocrine and other factor-regulated calcium reabsorption     107514224 (ADCY6)   09156 Nervous system    04724 Glutamatergic synapse     107514224 (ADCY6)    04727 GABAergic synapse     107514224 (ADCY6)    04725 Cholinergic synapse     107514224 (ADCY6)    04723 Retrograde endocannabinoid signaling     107514224 (ADCY6)   09157 Sensory system    04742 Taste transduction     107514224 (ADCY6)    04750 Inflammatory mediator regulation of TRP channels     107514224 (ADCY6)   09149 Aging    04211 Longevity regulating pathway     107514224 (ADCY6)    04213 Longevity regulating pathway - multiple species     107514224 (ADCY6)   09159 Environmental adaptation    04713 Circadian entrainment     107514224 (ADCY6)    04714 Thermogenesis     107514224 (ADCY6)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     107514224 (ADCY6)    05207 Chemical carcinogenesis - receptor activation     107514224 (ADCY6)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     107514224 (ADCY6)    05163 Human cytomegalovirus infection     107514224 (ADCY6)   09165 Substance dependence    05032 Morphine addiction     107514224 (ADCY6)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     107514224 (ADCY6)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     107514224 (ADCY6)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     107514224 (ADCY6) Enzymes [BR:ray01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      107514224 (ADCY6) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N Adcy_cons_dom HNOBA TBK1_ULD GBR2_CC Motif Other DBs NCBI-GeneID:  107514224 NCBI-ProteinID:  XP_016007219 LinkDB All DBs Position Unknown AA seq 1165 aa AA seqDB search MSWFSGLLVPKVDERKTAWGECNGQKRPRHGTRTSGFCAPRYMSCLQDAQPPSPTPAAPP RCPWQEEAFIRRGGPGKGTELGLRAVALGFEDTETTALGAADVAPNVAPRSSRSCWRRLV QVFQSKQFRSAKLERLYQRYFFQMNQSSLTLLMAVLVLLTAVLLTFHAAPAHPQPAYVAL LACAAVLFVVLMVVCNRHSFRQDSMWVVSYVVLGILAAVQVGGALAANPHSPSVGLWCPV FFVYITYTLLPIRMRAAVFSGLGLSTLHLILAWQLNRGDAFLWKQLGANMLLFFCTNVIG ICTHYPAEVSQRQAFQETRGYIQARLHLQHENRQQERLLLSVLPQHVAMEMKEDINTKKE DMMFHKIYIQKHDNVSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLAAENHCLRI KILGDCYYCVSGLPEARADHAHCCVEMGVDMIEAISLVREVTGVNVNMRVGIHSGRVHCG VLGLRKWQFDVWSNDVTLANHMEAGGRAGRIHITRATLQYLNGDYEVEPGRGGERNAYLK EQHIETFLILGASQKRKEEKAMLAKLQRTRANSMEGLMPRWVPDRAFSRSKDSKAFRQMG IDDSSKDNRGAQDALNPEDEVDEFLGRAIDARSIDQLRKDHVRRFLLTFQREDLEKKYSR KVDPRFGAYVACALLVFCFICFIQLLVFPHSTVMLGIYTGIFLLLLITVLTCAVYSCGSL FPKGLQHLSRSIVRSRAHSTAVGIFSVLLVFTSAIANMFTCNHTPIRTCAARMLNLTPAD ITVCHLQQLNYSLGLDAPLCEGTAPTCSFPEYFVGNVLLSLLASSVFLHISSIGKLAMIF VLGLIYLVLLLLGPPATIFDNYDLLLGVHGLASSNETFDGLDCPDAGRVALKYMTPVILL VFALALYLHAQQVESTARLDFLWKLQATGEKEEMEELQAYNRRLLHNILPKDVAAHFLAR ERRNDELYYQSCECVAVMFASIANFSEFYVELEANNEGVECLRLLNEIIADFDEIISEER FRQLEKIKTIGSTYMAASGLNASTYDQVGRSHITALADYAMRLMEQMKHINEHSFNNFQM KIGLNMGPVVAGVIGARKPQYDIWGNTVNVSSRMDSTGVPDRIQVTTDLYQVLAAKGYQL ECRGVVKVKGKGEMTTYFLNGGPSS NT seq 3498 nt NT seq  +upstreamnt  +downstreamnt atgtcatggttcagtggcctcctggtacccaaagtggatgaacggaaaacagcctggggg gaatgcaatgggcagaagcgcccgcgtcatgggactcggaccagtggcttctgcgcaccc cgctatatgagctgcctccaggatgcacagccacccagccccacccctgcagccccacct cggtgcccctggcaggaggaagccttcatccggaggggcggccccggcaagggcacagag ctggggctgcgggccgtggccctgggctttgaggacaccgagacaacagcgcttggggca gctgacgtggcacccaatgtggcacccaggagcagtcgatcctgttggcgccgtctggtt caggtgttccagtcgaagcagttccgctcagccaagctagagcgcctgtatcagcggtac ttcttccagatgaaccagagcagcttaacgctgctgatggcagtgctcgtgctgctcacg gctgtgctgctgaccttccatgccgcgcctgcccaccctcagcctgcctatgtggccctg ctggcctgtgcggccgtcctctttgtggtgctcatggtggtgtgtaatcgacacagcttt cgccaggactccatgtgggtggtgagctatgtggtgctgggcatcctggcagctgtgcag gttgggggtgccctggcagccaacccccacagcccctccgtaggcctttggtgccctgtg ttctttgtctacatcacctacactctcctacccatccgcatgcgggcagctgtcttcagt ggcctgggcctctccaccctgcatttgatcttggcctggcaactcaaccgtggtgatgcc ttcctctggaagcagctcggtgccaacatgctgctgttcttctgcacaaatgtcattggc atctgcacacactacccagctgaggtgtctcagcgccaggcctttcaagagacccgcggg tacatccaggcccggctgcacctgcagcatgagaatcggcagcaggaacgcctgctgctg tcagtgttgccccagcacgttgccatggagatgaaagaagacatcaacacaaagaaggaa gacatgatgttccacaagatctacatccagaagcatgacaatgtcagcatcctgtttgca gacattgaaggtttcaccagcctggcatcacagtgcactgcacaggaactggttatgacc ctgaatgagctctttgcccggtttgacaagcttgctgcagaaaatcactgcctaaggatc aagatcttaggggactgttactactgtgtgtcagggttgccagaggcccgggcagaccat gcccactgctgtgtggagatgggagtggacatgattgaggccatctcgctggtgcgtgag gtgacaggtgtgaacgtgaacatgcgcgtgggcatccacagtggacgtgtgcactgcggt gtccttggtctgcggaagtggcaattcgatgtgtggtccaatgacgtgactctggccaac cacatggaggcagggggccgggctggccgcatccacatcactcgggccacactgcagtac ctgaatggtgactacgaggtggagccgggccgtggtggtgagcgtaacgcgtacctcaag gagcagcacattgagaccttcctgatccttggtgccagccagaaacggaaagaggagaaa gccatgctggccaagctgcagcggacacgggccaactccatggaagggctgatgccacgc tgggtgcctgaccgggccttctcccggagcaaggactccaaggcattccgccagatgggc attgatgattccagcaaagacaaccggggtgcccaagatgctctgaaccctgaggatgaa gtagacgagttcctgggccgtgccatcgacgcccgcagcattgatcagctgcgcaaggac catgtgcgccggttcctgctcacttttcagagagaggatcttgaaaagaagtactcaagg aaagtggatccccgctttggagcctacgtggcctgtgccctgttggtcttctgcttcatc tgcttcatccaactgctcgtcttcccacactcaacagtgatgcttgggatctacaccggg atctttctgctgctgttgatcaccgtgctgacctgcgccgtgtactcctgtggctctctg ttccctaagggcctgcaacatctgtcacgcagcattgtgcgctctcgggcacacagcacc gccgttggcatcttttcagtcctgcttgtgttcacctctgccatcgctaacatgttcacc tgtaaccacacccccatacggacctgcgcagccaggatgctgaatttaacacctgctgac atcactgtctgccacctgcagcagctcaattactccctgggcctggatgctcccctgtgt gagggcaccgcacccacctgcagctttcccgagtacttcgtcgggaatgtgctgctgagt ctgttggccagctctgtcttcctacacatcagtagcatcggaaagttggccatgatcttt gtcttggggctcatctatttggtgctgcttctcctgggccccccagccaccatctttgac aactatgacctactgcttggtgtccatggcttggcttcttctaatgaaacttttgatggg ctggactgcccagatgcagggagggtggcactcaaatatatgacccctgtgattctgctg gtgtttgccctggccctgtatctgcatgctcagcaggtggaatcgactgcccgcctggac ttcctctggaaactgcaggcaacaggggagaaggaggagatggaagagctccaggcgtac aaccggcggctgttgcataacattctgcccaaggatgtagctgcccacttcctggcccgg gagcgccggaacgacgagctctactatcagtcgtgtgagtgtgtggctgtcatgtttgcc tccattgccaacttctctgagttctacgtggagctggaggcaaataatgagggtgtggag tgcctgcggctgctcaacgagattatcgctgattttgatgagatcatcagtgaggagcgg ttccggcagctggagaagatcaagactattggtagcacttacatggctgcctccgggctg aacgccagcacctatgaccaggtgggccgctcccacatcactgcccttgccgactatgcc atgcggctcatggagcagatgaagcacatcaatgagcactccttcaacaatttccagatg aagattggactgaacatgggcccagttgtggcaggtgtcattggggctcggaagccacag tatgacatctgggggaacacagtgaatgtctctagccgtatggacagcacgggggtccct gacagaatccaggtgaccactgacttgtaccaggttctggctgccaagggctatcagctg gagtgtcgaggagtggtcaaagtgaagggcaagggggagatgaccacctacttcctgaat gggggccccagcagttag

Rousettus aegyptiacus (Egyptian rousette): 107518038 Help Entry 107518038         CDS       T06036                                  Symbol ADCY5 Name (RefSeq) adenylate cyclase type 5 isoform X1   KO K08045   adenylate cyclase 5 [EC:4.6.1.1] Organism ray  Rousettus aegyptiacus (Egyptian rousette) Pathway ray00230   Purine metabolism ray01100   Metabolic pathways ray01522   Endocrine resistance ray04015   Rap1 signaling pathway ray04022   cGMP-PKG signaling pathway ray04024   cAMP signaling pathway ray04062   Chemokine signaling pathway ray04072   Phospholipase D signaling pathway ray04081   Hormone signaling ray04082   Neuroactive ligand signaling ray04114   Oocyte meiosis ray04211   Longevity regulating pathway ray04213   Longevity regulating pathway - multiple species ray04261   Adrenergic signaling in cardiomyocytes ray04270   Vascular smooth muscle contraction ray04371   Apelin signaling pathway ray04540   Gap junction ray04611   Platelet activation ray04713   Circadian entrainment ray04714   Thermogenesis ray04723   Retrograde endocannabinoid signaling ray04724   Glutamatergic synapse ray04725   Cholinergic synapse ray04726   Serotonergic synapse ray04727   GABAergic synapse ray04728   Dopaminergic synapse ray04750   Inflammatory mediator regulation of TRP channels ray04911   Insulin secretion ray04912   GnRH signaling pathway ray04913   Ovarian steroidogenesis ray04914   Progesterone-mediated oocyte maturation ray04915   Estrogen signaling pathway ray04916   Melanogenesis ray04918   Thyroid hormone synthesis ray04921   Oxytocin signaling pathway ray04923   Regulation of lipolysis in adipocytes ray04924   Renin secretion ray04925   Aldosterone synthesis and secretion ray04926   Relaxin signaling pathway ray04927   Cortisol synthesis and secretion ray04928   Parathyroid hormone synthesis, secretion and action ray04934   Cushing syndrome ray04935   Growth hormone synthesis, secretion and action ray04970   Salivary secretion ray04971   Gastric acid secretion ray04972   Pancreatic secretion ray04976   Bile secretion ray05012   Parkinson disease ray05030   Cocaine addiction ray05031   Amphetamine addiction ray05032   Morphine addiction ray05034   Alcoholism ray05163   Human cytomegalovirus infection ray05166   Human T-cell leukemia virus 1 infection ray05200   Pathways in cancer ray05207   Chemical carcinogenesis - receptor activation ray05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:ray00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     107518038 (ADCY5)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     107518038 (ADCY5)    04371 Apelin signaling pathway     107518038 (ADCY5)    04072 Phospholipase D signaling pathway     107518038 (ADCY5)    04024 cAMP signaling pathway     107518038 (ADCY5)    04022 cGMP-PKG signaling pathway     107518038 (ADCY5)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     107518038 (ADCY5)    04081 Hormone signaling     107518038 (ADCY5)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     107518038 (ADCY5)   09144 Cellular community - eukaryotes    04540 Gap junction     107518038 (ADCY5)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     107518038 (ADCY5)    04062 Chemokine signaling pathway     107518038 (ADCY5)   09152 Endocrine system    04911 Insulin secretion     107518038 (ADCY5)    04923 Regulation of lipolysis in adipocytes     107518038 (ADCY5)    04912 GnRH signaling pathway     107518038 (ADCY5)    04913 Ovarian steroidogenesis     107518038 (ADCY5)    04915 Estrogen signaling pathway     107518038 (ADCY5)    04914 Progesterone-mediated oocyte maturation     107518038 (ADCY5)    04921 Oxytocin signaling pathway     107518038 (ADCY5)    04926 Relaxin signaling pathway     107518038 (ADCY5)    04935 Growth hormone synthesis, secretion and action     107518038 (ADCY5)    04918 Thyroid hormone synthesis     107518038 (ADCY5)    04928 Parathyroid hormone synthesis, secretion and action     107518038 (ADCY5)    04916 Melanogenesis     107518038 (ADCY5)    04924 Renin secretion     107518038 (ADCY5)    04925 Aldosterone synthesis and secretion     107518038 (ADCY5)    04927 Cortisol synthesis and secretion     107518038 (ADCY5)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     107518038 (ADCY5)    04270 Vascular smooth muscle contraction     107518038 (ADCY5)   09154 Digestive system    04970 Salivary secretion     107518038 (ADCY5)    04971 Gastric acid secretion     107518038 (ADCY5)    04972 Pancreatic secretion     107518038 (ADCY5)    04976 Bile secretion     107518038 (ADCY5)   09156 Nervous system    04724 Glutamatergic synapse     107518038 (ADCY5)    04727 GABAergic synapse     107518038 (ADCY5)    04725 Cholinergic synapse     107518038 (ADCY5)    04728 Dopaminergic synapse     107518038 (ADCY5)    04726 Serotonergic synapse     107518038 (ADCY5)    04723 Retrograde endocannabinoid signaling     107518038 (ADCY5)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     107518038 (ADCY5)   09149 Aging    04211 Longevity regulating pathway     107518038 (ADCY5)    04213 Longevity regulating pathway - multiple species     107518038 (ADCY5)   09159 Environmental adaptation    04713 Circadian entrainment     107518038 (ADCY5)    04714 Thermogenesis     107518038 (ADCY5)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     107518038 (ADCY5)    05207 Chemical carcinogenesis - receptor activation     107518038 (ADCY5)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     107518038 (ADCY5)    05163 Human cytomegalovirus infection     107518038 (ADCY5)   09164 Neurodegenerative disease    05012 Parkinson disease     107518038 (ADCY5)   09165 Substance dependence    05030 Cocaine addiction     107518038 (ADCY5)    05031 Amphetamine addiction     107518038 (ADCY5)    05032 Morphine addiction     107518038 (ADCY5)    05034 Alcoholism     107518038 (ADCY5)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     107518038 (ADCY5)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     107518038 (ADCY5)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     107518038 (ADCY5) Enzymes [BR:ray01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      107518038 (ADCY5) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  AC_N Guanylate_cyc Adcy_cons_dom TBK1_ULD PEN-2 HILPDA GBR2_CC Motif Other DBs NCBI-GeneID:  107518038 NCBI-ProteinID:  XP_016014846 LinkDB All DBs Position Unknown AA seq 1259 aa AA seqDB search MSGSKSVSPPGYAAQTAAAPASRGGPEHRSAWGEADARANGYPHAPGGSARGSTKRPGGA VTPQQQQRLASRWRSDDDDDPPLSGDDPLAGGFGFSFRSKSAWQERGGDDCGRGSRRQRR GAAGGGSTRAPPAGGGGGSAAAAAAAGGTEVRPRSVELGLEERRGKGRGVDELEAGAVEG DGGSADGGSLAGSGAGPGPVLSLGSCCLALLQIFRSKKFPSDKLERLYQRYFFRLNQSSL TMLMAVLVLVCLVMLAFHAARPPLQLPYLVVLAAAVGVILVMAVLCNRAAFHQDHMGLAC YALIAVVLVVQVVGLLLPQPRSASEGIWWTVFFIYTIYTLLPVRMRAAVLSGVLLSALHL AIALRTNAQDQFLLKQLVSNVLIFSCTNIVGVCTHYPAEVSQRQAFQETRECIQARLHSQ RENQQQERLLLSVLPRHVAMEMKADINAKQEDMMFHKIYIQKHDNVSILFADIEGFTSLA SQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVEMGM DMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGKAG RIHITKATLNYLNGDYEVEPGCGGERNAYLKEHSIETFLILRCTQKRKEEKAMIAKMNRQ RTNSIGHNPPHWGAERPFYNHLGGNQVSKEMKRMGFEDPKDKNAQESANPEDEVDEFLGR AIDARSIDRLRSEHVRKFLLTFREPDLEKKYSKQVDDRFGAYVACASLVFLFICFVQITI VPHSVFMLSFYLTCFVLLTLVIFVSVIYSCVKLFPAPLQTLSKKIVRSKVNSTLVGVFTI TLVFLAAFVNMFMCNSKDLFGCLADEHNVSTSQINACHVVESAFNYSLGDEQGFCGSPWP NCNFPEYFTYSVLLSLLACSVFLQISCIGKLVLMLAIELIYVLVVEVPGVTLFDNADLLV TANAIDFNNNGTSQCPEHATKVALKVVTPIVISVFVLALYLHAQQVESTARLDFLWKLQA TEEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANFSE FYVELEANNEGVECLRLLNEIIADFDEIISEDRFRQLEKIKTIGSTYMAASGLNDSTYDK VGKTHIKALADFAMKLMDQMKYINEHSFNNFQMKIGLNIGPVVAGVIGARKPQYDIWGNT VNVASRMDSTGVPDRIQVTTDMYQVLAANTYQLECRGVVKVKGKGEMMTYFLNGGPPLS NT seq 3780 nt NT seq  +upstreamnt  +downstreamnt atgtccggctccaaaagcgtgagccccccgggctacgcggcgcagacagcggcggcgcca gcgtcccggggaggcccggaacaccgctccgcgtggggagaggcagatgcccgcgccaat ggctacccccacgcccccggcggttcggcccgcggctccaccaagagacccgggggggcg gtgaccccgcagcagcagcagcgcctggccagccgctggcgcagcgacgacgacgacgac cctccgctgagtggcgacgaccccctggccgggggctttggcttcagcttccgctctaag tcagcctggcaggagcgcggcggcgacgactgcggacgcggcagccgccggcagcggcgg ggcgcggctggcgggggcagcacccgggcgccccctgcgggcggcggtggcggctcggcg gccgcggcggccgcagccggcgggaccgaggtgcgcccccgctcggtggagctgggtctg gaggagcggcggggcaagggccgcggggtcgacgagctggaggccggcgccgtcgagggc gacgggggctccgcggatggcggcagcttggcgggctcgggcgcgggccccggcccggtg ctgtctctgggctcctgctgcctcgcactactgcagatattccgctccaagaagttcccg tcggacaagctggagcggctgtaccagcgctacttcttccgcctgaaccagagcagcctg accatgctcatggccgtgctagtgctcgtgtgcctcgtcatgttggccttccacgcggcg cggcccccgctccagctgccctacctggtggtgctggcggccgctgtgggcgtgatcctt gtcatggccgtgctctgcaaccgcgccgcctttcaccaggaccacatgggcctggcctgc tacgcgctcatcgcggtggtgctggtcgtccaggtggtgggcctgctgctgccccagcca cgaagcgcctccgagggcatctggtggacggtgttcttcatctacaccatctacacgctg ctacccgtgcgcatgcgggccgcagtactcagcggggtgctcctgtctgccctccacctg gccatcgccctgcgaaccaacgcccaggaccagttcctgctcaaacagctggtctccaat gtcctcatcttctcctgcaccaacatcgtgggtgtctgcacccactacccggcagaggtc tcccagagacaggcgttccaggagacccgggagtgtatccaggcacggctccactcacag cgggagaaccagcagcaggagcggctcctgctgtctgtccttccccgtcatgttgccatg gagatgaaagcagacatcaacgccaagcaggaggatatgatgttccataagatttacatc cagaaacatgacaacgtgagcatcctgtttgctgacatcgagggcttcaccagcttggcg tcccagtgcacggcccaagagctggtcatgaccctcaacgagctcttcgcccgcttcgac aagctggctgcggagaatcactgtttacgtattaagatcctgggggattgttattactgt gtctcggggctgcctgaagcgagggccgaccacgcccactgctgcgtggagatgggcatg gacatgattgaggccatctcgttggtccgggaggtgacaggggtgaacgtgaacatgcgc gtgggaattcacagcgggcgagtacactgcggtgtccttggtctcaggaagtggcagttc gacgtctggtctaacgacgtcacgctggccaaccacatggaggctggaggcaaggctgga cgcatccacatcaccaaggccacactcaactacctgaatggagactacgaagtggagccc ggctgtgggggcgagcgcaacgcctacctcaaggagcacagcatcgagaccttcctcatc ctgcgctgcacccagaagcggaaagaagagaaggccatgatcgccaagatgaatcgccag agaaccaactccatcgggcacaacccgccgcactggggggctgagcgccccttctacaac cacttgggtggcaaccaggtgtctaaggagatgaagcggatgggtttcgaagaccccaag gacaagaatgcccaggaaagcgcgaaccccgaggacgaagtggatgaatttctgggccga gccatcgatgccaggagtattgacaggctgcggtctgagcatgttcgcaagttcctcttg accttcagggagcctgacttagagaagaagtactccaagcaggtggatgaccgattcggt gcctatgtggcatgtgcctcgcttgtcttcctcttcatttgctttgtccagatcaccatc gtgccccactccgtgttcatgttgagtttctacctgacctgtttcgtgctgctgaccttg gtgatatttgtgtccgtcatctactcctgtgtgaagctcttccccgccccgctgcagacc ctctccaagaagatcgtgcggtccaaggtgaacagcaccctggttggggtgttcaccatc accctggtgttcctggcagcgtttgtcaacatgttcatgtgcaactccaaggacctgttc ggctgcctggcagatgagcacaacgtcagcaccagccagatcaacgcttgccacgtggtg gagtcggccttcaactacagcctgggtgatgagcagggattctgcggcagcccctggccc aactgcaacttccctgagtacttcacctacagcgtgctgctcagcctgctggcctgctcc gtgttcctgcagatcagctgcatcgggaagctggtgctcatgctggccatcgagctcata tatgtgctcgtcgtcgaagtgcccggtgtcacactctttgacaatgcagacctgctagtc accgccaacgccatagacttcaacaacaacgggacctcccagtgccctgagcacgcgacc aaagtggcgctgaaggtggtgacgcccattgtcatctcagtctttgtgctggccctgtac ctgcacgcccagcaggtggagtccaccgcccgcctcgacttcctctggaaactacaggcc acggaagagaaggaggagatggaggagctgcaggcctacaaccggcggctgctgcacaac atcctgcccaaggacgtggccgcccacttcctggcccgggagcggcgcaacgacgagctg tactatcagtcgtgtgagtgtgtggccgtcatgttcgcctccattgccaacttctccgag ttctacgtggagctggaggccaacaacgagggcgtcgagtgcctgcggctgcttaatgaa atcatcgccgatttcgacgagatcatcagcgaggatcggttcaggcagctggaaaagatc aagaccattggcagcacctacatggctgcctcaggcctcaatgattccacctatgacaaa gtgggcaagacccacatcaaggctctggccgacttcgccatgaagctgatggaccagatg aagtacatcaacgagcactccttcaacaacttccagatgaagattgggctcaacattggc cccgtggtggccggggtgatcggggcccgcaagcctcagtacgacatctggggcaatacg gtgaacgtggccagccgcatggacagcaccggtgtgcctgaccgcatccaggtcaccaca gacatgtatcaggtgctggctgccaacacataccagctggagtgccggggtgtggtcaag gtcaagggcaaaggagagatgatgacctacttcctcaacggagggcccccgctcagttag

Rousettus aegyptiacus (Egyptian rousette): 107521680 Help Entry 107521680         CDS       T06036                                  Symbol ADCY9 Name (RefSeq) adenylate cyclase type 9   KO K08049   adenylate cyclase 9 [EC:4.6.1.1] Organism ray  Rousettus aegyptiacus (Egyptian rousette) Pathway ray00230   Purine metabolism ray01100   Metabolic pathways ray01522   Endocrine resistance ray04015   Rap1 signaling pathway ray04020   Calcium signaling pathway ray04022   cGMP-PKG signaling pathway ray04024   cAMP signaling pathway ray04062   Chemokine signaling pathway ray04072   Phospholipase D signaling pathway ray04081   Hormone signaling ray04082   Neuroactive ligand signaling ray04114   Oocyte meiosis ray04211   Longevity regulating pathway ray04213   Longevity regulating pathway - multiple species ray04261   Adrenergic signaling in cardiomyocytes ray04270   Vascular smooth muscle contraction ray04371   Apelin signaling pathway ray04540   Gap junction ray04611   Platelet activation ray04713   Circadian entrainment ray04714   Thermogenesis ray04723   Retrograde endocannabinoid signaling ray04724   Glutamatergic synapse ray04725   Cholinergic synapse ray04727   GABAergic synapse ray04750   Inflammatory mediator regulation of TRP channels ray04911   Insulin secretion ray04912   GnRH signaling pathway ray04913   Ovarian steroidogenesis ray04914   Progesterone-mediated oocyte maturation ray04915   Estrogen signaling pathway ray04916   Melanogenesis ray04918   Thyroid hormone synthesis ray04921   Oxytocin signaling pathway ray04923   Regulation of lipolysis in adipocytes ray04925   Aldosterone synthesis and secretion ray04926   Relaxin signaling pathway ray04927   Cortisol synthesis and secretion ray04928   Parathyroid hormone synthesis, secretion and action ray04934   Cushing syndrome ray04935   Growth hormone synthesis, secretion and action ray04961   Endocrine and other factor-regulated calcium reabsorption ray04962   Vasopressin-regulated water reabsorption ray04970   Salivary secretion ray04971   Gastric acid secretion ray04972   Pancreatic secretion ray04976   Bile secretion ray05032   Morphine addiction ray05163   Human cytomegalovirus infection ray05166   Human T-cell leukemia virus 1 infection ray05200   Pathways in cancer ray05207   Chemical carcinogenesis - receptor activation ray05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:ray00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     107521680 (ADCY9)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     107521680 (ADCY9)    04371 Apelin signaling pathway     107521680 (ADCY9)    04020 Calcium signaling pathway     107521680 (ADCY9)    04072 Phospholipase D signaling pathway     107521680 (ADCY9)    04024 cAMP signaling pathway     107521680 (ADCY9)    04022 cGMP-PKG signaling pathway     107521680 (ADCY9)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     107521680 (ADCY9)    04081 Hormone signaling     107521680 (ADCY9)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     107521680 (ADCY9)   09144 Cellular community - eukaryotes    04540 Gap junction     107521680 (ADCY9)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     107521680 (ADCY9)    04062 Chemokine signaling pathway     107521680 (ADCY9)   09152 Endocrine system    04911 Insulin secretion     107521680 (ADCY9)    04923 Regulation of lipolysis in adipocytes     107521680 (ADCY9)    04912 GnRH signaling pathway     107521680 (ADCY9)    04913 Ovarian steroidogenesis     107521680 (ADCY9)    04915 Estrogen signaling pathway     107521680 (ADCY9)    04914 Progesterone-mediated oocyte maturation     107521680 (ADCY9)    04921 Oxytocin signaling pathway     107521680 (ADCY9)    04926 Relaxin signaling pathway     107521680 (ADCY9)    04935 Growth hormone synthesis, secretion and action     107521680 (ADCY9)    04918 Thyroid hormone synthesis     107521680 (ADCY9)    04928 Parathyroid hormone synthesis, secretion and action     107521680 (ADCY9)    04916 Melanogenesis     107521680 (ADCY9)    04925 Aldosterone synthesis and secretion     107521680 (ADCY9)    04927 Cortisol synthesis and secretion     107521680 (ADCY9)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     107521680 (ADCY9)    04270 Vascular smooth muscle contraction     107521680 (ADCY9)   09154 Digestive system    04970 Salivary secretion     107521680 (ADCY9)    04971 Gastric acid secretion     107521680 (ADCY9)    04972 Pancreatic secretion     107521680 (ADCY9)    04976 Bile secretion     107521680 (ADCY9)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     107521680 (ADCY9)    04961 Endocrine and other factor-regulated calcium reabsorption     107521680 (ADCY9)   09156 Nervous system    04724 Glutamatergic synapse     107521680 (ADCY9)    04727 GABAergic synapse     107521680 (ADCY9)    04725 Cholinergic synapse     107521680 (ADCY9)    04723 Retrograde endocannabinoid signaling     107521680 (ADCY9)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     107521680 (ADCY9)   09149 Aging    04211 Longevity regulating pathway     107521680 (ADCY9)    04213 Longevity regulating pathway - multiple species     107521680 (ADCY9)   09159 Environmental adaptation    04713 Circadian entrainment     107521680 (ADCY9)    04714 Thermogenesis     107521680 (ADCY9)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     107521680 (ADCY9)    05207 Chemical carcinogenesis - receptor activation     107521680 (ADCY9)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     107521680 (ADCY9)    05163 Human cytomegalovirus infection     107521680 (ADCY9)   09165 Substance dependence    05032 Morphine addiction     107521680 (ADCY9)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     107521680 (ADCY9)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     107521680 (ADCY9)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     107521680 (ADCY9) Enzymes [BR:ray01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      107521680 (ADCY9) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc Adcy_cons_dom AC_N Motif Other DBs NCBI-GeneID:  107521680 NCBI-ProteinID:  XP_016022072 UniProt:  A0A7J8EWF4 LinkDB All DBs Position Unknown AA seq 1353 aa AA seqDB search MASPPHQQLLLHHSTEVSCDSSGDSNSVRVKINPKQLSSNSHPKHCKYSISSSCSSSGDS GGVPRRVGAGGRLRRQKKLPQLFERASSRWWDPKFDSVNLEEACLERCFPQTQRRFRYAL FYIGFACLLWSIYFGVHMRSKLIVMAVPALCFLVVCVGFFLFTFTKLYARHYVGTSLVLT LLVFALTLAAQFQVLTPLSGRVDSSNHTLAAKPTDTCLSQVGSFSMCIEVLFLLYTVMHL PLYLSLFLGVAYSVLFETFGYHFQSEDCFPSPEIGPPHWELLSRALLHVCIHAIGIHLFI MSQVRSRSTFLKVGQSIMHGKDLEVEKALKERMIHSVMPRIIADDLMKQGDEESENSVKR HATSSPKNRKKKSSIQKAPIAFRPFKMQQIEEVSILFADIVGFTKMSANKSAHALVGLLN DLFGRFDRLCEETKCEKISTLGDCYYCVAGCPEPRADHAYCCIEMGLGMIRAIEHFCQEK KEMVNMRVGVHTGTVLCGILGMRRFKFDVWSNDVNLANLMEQLGVAGKVHISEATAKYLD DRYEMEDGRVTERLGQSVVVDQLKGLKTYLIAGQRAKESHCSCSEALLSGFEVIDGSQVS SGPRGQGTASPGSVSDLAQTVKTFDNLKTCPSCGITFAPKSEGGTGGGAVQNGCQEEHKN STKASGGPNSKTQNGLLSPPQEEKLTNSQTSLCEILQEKGRWAGVSLDQSALLPLRFKNI REKTDAHFVDVIKEDSLMKDYFFKPPINQFSLNFLDQELEQAYRTSYQEEVMKNSPVKTF ASATFSSLLDVFLSTTVFLILSITCFLKYWAAATPPPPAALAVFGAALLLEVLSLVVSVR MVFFLEDVMACTKRLLEWIAGWLPRHFIGAILVSLPALAVYSHVTSEFETNIHFTVFTGS AILIAVVHYCNFCQLSSWMRSSLATVVGAGPLLLLYISLCPDSSILESPFDAVQNFSSVR NPCNSSLPHDSRRPASLIGQEVILVFFLLLLLVWFLNREFEVSYRLHYHGDVEADLHRTK IQSMRDQADWLLRNIIPYHVAEQLKVSQTYSKNHDSGGVIFASIVNFSEFYEENYEGGKE CYRVLNELIGDFDELLSKPDYSSIEKIKTIGATYMAASGLNATQCQDGSHPQEHLQILFE FAKEMMRVVDDFNNNMLWFNFKLRVGFNHGPLTAGVIGTTKLLYDIWGDTVNIASRMDTT GVECRIQVSEESYRVLSKMGYDFDYRGTVNVKGKGQMKTYLYPKCMDNGVVPQHQLSISP DIRVQVDGSIGRSPTDEIANLVPSVQNSDKTSLGSENNTQAKDCHLSSKRPWKEPVKAEE RCRFGKAIEKSDCEEMGMEEANELTKLNVSKSV NT seq 4062 nt NT seq  +upstreamnt  +downstreamnt atggcttccccgccccaccagcagctgctgctgcaccacagcaccgaggtgagttgtgac tccagcggagacagcaacagcgtgagggtcaaaatcaaccccaagcagctatcgtccaac agccaccccaaacactgcaagtacagcatctcttccagctgtagcagctcaggcgactca ggcggggtcccccggagagtgggtgctggaggccgcctgcgcaggcagaagaaactgccc caactgttcgagagggcctccagccggtggtgggaccccaaattcgactcggtgaacctg gaggaggcttgccttgagcgctgcttcccgcagacccagcgccgcttccggtacgctctc ttctacattggcttcgcctgcctgctctggagcatctattttggggtccacatgagatcc aaactgatagtcatggcagtccctgctctgtgcttccttgtggtgtgtgtgggctttttc ctgtttaccttcaccaaactgtatgcccgacattacgtggggacctcgctggttctcacc ctcctagtgttcgccctgaccctggctgcccagtttcaggttctgacgcctctctcagga cgtgttgacagctccaatcatactctcgcagccaagcccacagacacttgcttatctcaa gtggggagcttttccatgtgcatcgaagtgctctttttgctctacaccgtcatgcactta cctttgtacttgagcttgtttttgggagtggcctattctgttctttttgagacctttggc tatcatttccaaagtgaagactgcttcccctcacctgaaatagggcctccgcactgggag ctgttgagccgagccctgctccacgtctgtattcatgccattgggatccacctattcatc atgtcccaggtgagatccaggagcacctttctcaaggtgggacagtccattatgcacgga aaggatctggaagtggaaaaagccctgaaagagaggatgattcattctgtgatgccaaga atcatagctgatgacttgatgaaacagggggacgaggagagcgagaattctgtgaaaagg cacgccacctccagccccaagaacaggaagaaaaaatcttccatacagaaagcccctata gcattccgcccgtttaaaatgcagcagattgaagaggtcagtattttatttgcagacatc gtaggcttcactaagatgagtgccaacaagtccgctcatgccctggtgggtctcctcaat gatctgttcggtcgctttgaccggttgtgtgaagagaccaagtgtgagaaaatcagcacc ctgggagactgctactactgcgtggcagggtgccccgagccccgggctgatcatgcctac tgctgcatcgaaatgggcttgggcatgataagagctatcgagcacttctgtcaggagaag aaagagatggtgaacatgcgtgttggggttcacacagggactgtcttgtgcggcatcttg ggcatgaggaggttcaaattcgatgtgtggtccaatgacgtgaacctggccaatctcatg gagcagctgggagtggctggcaaggttcacatttctgaggccactgcaaaatacctagat gatcggtacgaaatggaagatgggagagttactgaacgccttggccagagcgttgttgtt gaccagttgaaaggtttgaagacatacctgatagcgggtcagagagcgaaggagtctcat tgcagctgttcagaggccttgctttcgggctttgaggtcattgacggctcacaggtgtcc tcaggccctaggggacaggggacagcatcgccagggagtgtcagtgacttggcacagact gtcaaaacctttgataatcttaagacctgcccttcctgcggaatcacttttgctcccaaa tcggaaggtggcacaggaggaggagcagtgcaaaacggctgtcaggaggagcataaaaac agcaccaaggcttctggaggacctaattctaaaacgcaaaatggacttctgagcccaccc caagaggagaagctcaccaatagccagacctccctgtgtgagattctacaggaaaaggga aggtgggcaggtgtcagcttggaccagtctgctctccttccactgaggttcaagaacatc cgggagaaaacagacgcccactttgttgatgttatcaaagaagacagcctgatgaaggat tatttttttaagccacccattaatcagtttagcttgaacttcttggatcaggagctagag caagcctacaggaccagttatcaagaagaggttatgaagaattctcctgtgaagactttt gccagtgccaccttcagctccctcttggatgtgtttctgtcaacaacggtgtttctgatt ctctccatcacctgcttcctgaagtactgggctgccgccacgcctcccccgcctgccgca ctggcagtcttcggagcggccctgctgctggaggtgctgtccctcgtggtgtctgtcagg atggtatttttcctggaggatgtgatggcttgtaccaagcgcctgctggagtggatagcc ggctggctcccacgccacttcatcggggccatcctggtgtctctcccggctctcgcagtt tattcacatgtcacctcggaatttgagacaaacatacatttcacggtgttcacgggctcg gccatcttgatcgccgttgtgcactactgtaacttctgccagctcagctcctggatgcgg tcctccttagctactgtcgtcggggctgggcccctccttctgctctacatttccttgtgc ccggacagttccatactagagtcaccctttgatgcagtacagaatttcagttccgtgagg aatccctgcaatagttcattgccacatgacagcaggagaccagccagcctgattggccag gaggtgattcttgtcttctttctcctgctcttgttggtctggttcctgaatcgagaattc gaagtcagctaccgccttcactaccatggggatgtggaggcggaccttcaccgcaccaaa atccagagcatgagggatcaagctgactggctgctgaggaacatcatcccctaccatgtg gccgaacagctgaaggtttctcagacctactccaagaaccatgacagtgggggagtcatc tttgccagcattgtcaacttcagcgagttctacgaggaaaactacgagggaggcaaggag tgctaccgggtcctcaacgagctgatcggggacttcgatgagctcctgagcaagccagac tacagcagcattgagaagatcaagaccattggggccacgtacatggccgcgtcagggctg aacgccacacagtgccaggacggcagccacccgcaggagcacctgcagattctgtttgag tttgccaaggagatgatgcgcgtggtggacgacttcaacaacaacatgctgtggttcaac ttcaagctcagagtcggcttcaaccacgggcccctgacagcaggggtcatcggaaccacc aagctactgtacgacatctggggagacaccgtcaacatcgccagcaggatggacaccacg ggggtggagtgccgcatccaggtgagtgaagagagctaccgcgtcctcagcaagatgggc tacgactttgactacaggggcacagtgaacgtcaaaggcaaaggtcagatgaagacctac ctttacccaaagtgcatggacaacggggtcgtgccgcagcaccagctgtccatctcccca gacatccgagtccaggtggacggcagcatcggacggtcccccacggacgagattgccaac ctggtgccttccgtacagaactcggacaagacgtctctgggttctgagaacaacacacag gccaaggactgtcacctgtcttcaaagagaccctggaaggagcctgtcaaagccgaagaa aggtgtcgattcggcaaagccatagagaaaagcgactgtgaagaaatggggatggaagaa gccaatgaactcaccaagctcaatgtctcaaagagtgtgtga

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