| Entry |
|
|---|
| Name |
Acebutolol hydrochloride (JP18/USP);
Sectral (TN) |
|---|
| Product |
|
|---|
| Generic |
|
|---|
| Formula |
C18H28N2O4. HCl
|
|---|
| Exact mass |
372.1816
|
|---|
| Mol weight |
372.8869
|
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| Structure |
|
|---|
| Simcomp |
|
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| Class |
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01464 beta-Adrenergic receptor antagonist (Beta blocker)
DG01461 beta1-Adrenergic receptor antagonist
DG01653 Antiarrhythmics
DG01806 Class II antiarrhythmic agent
|
|---|
| Remark |
| Product (DG00314): | D00597<US> |
|
|---|
| Efficacy |
Antiarrhythmic, Antihypertensive, Vasodilator, beta1-Adrenergic receptor antagonist |
|---|
| Disease |
|
|---|
| Comment |
Propranolol derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04261 | Adrenergic signaling in cardiomyocytes |
|
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| Interaction |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C07 BETA BLOCKING AGENTS
C07A BETA BLOCKING AGENTS
C07AB Beta blocking agents, selective
C07AB04 Acebutolol
D00597 Acebutolol hydrochloride (JP18/USP) <US>
USP drug classification [BR:br08302]
Cardiovascular Agents
Antiarrhythmics
Vaughn Williams-Class II
Acebutolol
D00597 Acebutolol hydrochloride (JP18/USP)
Beta-adrenergic Blocking Agents
Beta-adrenergic Blocking Agents, Other
Acebutolol
D00597 Acebutolol hydrochloride (JP18/USP)
Drug groups [BR:br08330]
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01464 beta-Adrenergic receptor antagonist (Beta blocker)
DG01461 beta1-Adrenergic receptor antagonist
DG00314 Acebutolol
D00597 Acebutolol hydrochloride
DG01653 Antiarrhythmics
DG01806 Class II antiarrhythmic agent
DG00314 Acebutolol
D00597 Acebutolol hydrochloride
Drug classes [BR:br08332]
Cardiovascular agent
DG01653 Antiarrhythmics
D00597 Acebutolol hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRB1
D00597 Acebutolol hydrochloride (JP18/USP) <US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00597 Acebutolol hydrochloride
Drug groups [BR:br08330]
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01464 beta-Adrenergic receptor antagonist (Beta blocker)
DG01461 beta1-Adrenergic receptor antagonist
DG00314 Acebutolol
DG01653 Antiarrhythmics
DG01806 Class II antiarrhythmic agent
DG00314 Acebutolol
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 25
1 C8y C 21.9841 -14.0731
2 C8y C 20.7938 -14.7732
3 C8x C 23.2443 -14.7732
4 O2a O 21.9841 -12.6728
5 C8x C 20.7938 -16.1735
6 C5a C 19.5336 -14.0731
7 C8x C 23.2443 -16.1035
8 C1b C 23.1743 -11.9727
9 C8y C 22.0541 -16.8737
10 C1a C 18.3433 -14.7732
11 O5a O 19.5336 -12.6728
12 C1c C 24.3646 -12.6028
13 N1b N 22.0541 -18.2740
14 C1b C 25.6248 -11.9026
15 O1a O 24.3646 -14.0031
16 C5a C 20.8638 -18.9741
17 N1b N 26.8151 -12.6028
18 C1b C 19.6036 -18.2740
19 O5a O 20.8638 -20.3744
20 C1c C 28.0053 -11.9026
21 C1b C 18.4133 -19.0441
22 C1a C 29.2656 -12.5328
23 C1a C 28.0053 -10.5024
24 C1a C 17.2231 -18.3440
25 X Cl 31.9262 -16.3136
BOND 24
1 1 2 1
2 1 3 2
3 1 4 1
4 2 5 2
5 2 6 1
6 3 7 1
7 4 8 1
8 5 9 1
9 6 10 1
10 6 11 2
11 8 12 1
12 9 13 1
13 12 14 1
14 12 15 1
15 13 16 1
16 14 17 1
17 16 18 1
18 16 19 2
19 17 20 1
20 18 21 1
21 20 22 1
22 20 23 1
23 21 24 1
24 7 9 2
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