Entry |
|
Name |
Rocuronium bromide (JAN/USP/INN); Zemuron (TN) |
Product |
|
Generic |
ROCURONIUM (Bryant Ranch Prepack), ROCURONIUM (Fresenius Kabi USA), ROCURONIUM (Fresenius Kabi USA), ROCURONIUM (Fresenius Kabi USA), ROCURONIUM (Phlow Corporation), ROCURONIUM (Piramal Critical Care), ROCURONIUM BROMIDE (Almaject), ROCURONIUM BROMIDE (BE Pharmaceuticals), ROCURONIUM BROMIDE (Baxter Healthcare Corporation), ROCURONIUM BROMIDE (Caplin Steriles Limited), ROCURONIUM BROMIDE (Civica), ROCURONIUM BROMIDE (Eugia US LLC), ROCURONIUM BROMIDE (Gland Pharma Limited), ROCURONIUM BROMIDE (HF Acquisition Co LLC), ROCURONIUM BROMIDE (HF Acquisition Co LLC), ROCURONIUM BROMIDE (HF Acquisition Co LLC), ROCURONIUM BROMIDE (HF Acquisition Co LLC), ROCURONIUM BROMIDE (HF Acquisition Co LLC), ROCURONIUM BROMIDE (HF Acquisition Co LLC), ROCURONIUM BROMIDE (Hikma Pharmaceuticals USA), ROCURONIUM BROMIDE (Hospira), ROCURONIUM BROMIDE (Hospira), ROCURONIUM BROMIDE (Hospira), ROCURONIUM BROMIDE (Hospira), ROCURONIUM BROMIDE (Lupin Pharmaceuticals), ROCURONIUM BROMIDE (Medical Purchasing Solutions), ROCURONIUM BROMIDE (Medical Purchasing Solutions), ROCURONIUM BROMIDE (Medical Purchasing Solutions), ROCURONIUM BROMIDE (Medical Purchasing Solutions), ROCURONIUM BROMIDE (Medical Purchasing Solutions), ROCURONIUM BROMIDE (Meitheal Pharmaceuticals), ROCURONIUM BROMIDE (Mylan Institutional LLC), ROCURONIUM BROMIDE (Sagent Pharmaceuticals), ROCURONIUM BROMIDE (Sagent Pharmaceuticals), ROCURONIUM BROMIDE (Sandoz), ROCURONIUM BROMIDE (Solco Healthcare US), ROCURONIUM BROMIDE (XGen Pharmaceuticals DJB) |
Formula |
C32H53N2O4. Br
|
Exact mass |
608.3189
|
Mol weight |
609.68
|
Structure |
|
Simcomp |
|
Class |
Musculo-skeletal system agent
DG02029 Muscle relaxant
DG01696 Peripherally-acting muscle relaxant
DG03117 Nondepolarizing neuromuscular blocking agent
DG01742 Quaternary ammonium compound type muscle relaxant
|
Remark |
Therapeutic category: | 1229 |
|
Efficacy |
Skeletal muscle relaxant, Neuromuscular blocking agent, Muscarinic acetylcholine receptor antagonist |
Comment |
Quaternary ammonium compound
|
Target |
|
Pathway |
hsa04080 | Neuroactive ligand-receptor interaction |
|
Interaction |
|
Structure map |
map07221 | Nicotinic cholinergic receptor antagonists |
|
Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
M MUSCULO-SKELETAL SYSTEM
M03 MUSCLE RELAXANTS
M03A MUSCLE RELAXANTS, PERIPHERALLY ACTING AGENTS
M03AC Other quaternary ammonium compounds
M03AC09 Rocuronium bromide
D00765 Rocuronium bromide (JAN/USP/INN) <JP/US>
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
12 Agents affecting peripheral nervous system
122 Skeletal muscle relaxants
1229 Others
D00765 Rocuronium bromide (JAN/USP/INN)
Drug groups [BR:br08330]
Musculo-skeletal system agent
DG02029 Muscle relaxant
DG01696 Peripherally-acting muscle relaxant
DG03117 Nondepolarizing neuromuscular blocking agent
D00765 Rocuronium bromide
DG01742 Quaternary ammonium compound type muscle relaxant
D00765 Rocuronium bromide
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Acetylcholine (muscarinic)
CHRM
D00765 Rocuronium bromide (JAN/USP/INN) <JP/US>
Ion channels
Ligand-gated ion channels
Acetylcholine (nicotinic)
CHRN (neuronal type)
D00765 Rocuronium bromide (JAN/USP/INN) <JP/US>
New drug approvals in Japan [br08318.html]
Drugs with new active ingredients
D00765
|
Other DBs |
|
LinkDB |
|
KCF data |
ATOM 39
1 C1y C 7.4200 -8.9600
2 C1y C 7.4200 -10.3600
3 C1x C 8.6324 -11.0600
4 C1y C 9.8449 -10.3600
5 C1z C 9.8449 -8.9600
6 C1x C 8.6324 -8.2600
7 C1x C 11.0573 -11.0600
8 C1x C 12.2697 -10.3600
9 C1y C 12.2697 -8.9600
10 C1y C 11.0573 -8.2600
11 C1y C 13.4822 -8.2600
12 C1z C 13.4822 -6.8600
13 C1x C 12.2697 -6.1600
14 C1x C 11.0573 -6.8600
15 C1x C 15.9070 -8.2600
16 C1y C 15.9070 -6.8600
17 C1y C 14.6946 -6.1600
18 O1a O 6.2076 -11.0600
19 N1y N 6.2076 -8.2600
20 C1a C 9.8449 -7.5600
21 C1a C 13.4822 -5.4600
22 N2y N 17.1066 -6.1673 #+
23 O7a O 14.6946 -4.4100
24 C1x C 17.1066 -4.7673
25 C7a C 13.4862 -3.7123
26 C1a C 12.2927 -4.4016
27 O6a O 13.4861 -2.3102
28 C1x C 18.4381 -6.5999
29 C1x C 19.2610 -5.4673
30 C1x C 18.4381 -4.3347
31 C1b C 17.1066 -7.5673
32 C2b C 18.2959 -8.2540
33 C2a C 18.2960 -9.6598
34 C1x C 6.2076 -6.8602
35 C1x C 4.9951 -6.1602
36 O2x O 3.7827 -6.8602
37 C1x C 3.7827 -8.2600
38 C1x C 4.9951 -8.9600
39 X Br 16.8700 -3.0100 #-
BOND 43
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 5 6 1
6 1 6 1
7 4 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 5 10 1
12 9 11 1
13 11 12 1
14 12 13 1
15 13 14 1
16 10 14 1
17 11 15 1
18 15 16 1
19 16 17 1
20 12 17 1
21 2 18 1 #Down
22 1 19 1 #Up
23 5 20 1 #Up
24 12 21 1 #Up
25 16 22 1 #Up
26 17 23 1 #Up
27 22 24 1
28 23 25 1
29 25 26 1
30 25 27 2
31 22 28 1
32 28 29 1
33 29 30 1
34 24 30 1
35 22 31 1
36 31 32 1
37 32 33 2
38 19 34 1
39 34 35 1
40 35 36 1
41 36 37 1
42 37 38 1
43 19 38 1
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