KEGG   DRUG: Amlodipine besilate and atorvastatin calcium
Entry
D08488            Mixture   Drug                                   
Name
Amlodipine besilate and atorvastatin calcium;
Caduet (TN)
Product
CADUET (Pfizer Laboratories Div Pfizer)
  Generic
AMLODIPINE AND ATORVASTATIN (Apotex Corp.), AMLODIPINE AND ATORVASTATIN (Bryant Ranch Prepack), AMLODIPINE AND ATORVASTATIN (Bryant Ranch Prepack), AMLODIPINE AND ATORVASTATIN (Bryant Ranch Prepack), AMLODIPINE AND ATORVASTATIN (Bryant Ranch Prepack), AMLODIPINE AND ATORVASTATIN (Bryant Ranch Prepack), AMLODIPINE AND ATORVASTATIN (Bryant Ranch Prepack), AMLODIPINE AND ATORVASTATIN (Mylan Pharmaceuticals), AMLODIPINE AND ATORVASTATIN (Prasco Laboratories), AMLODIPINE BESYLATE AND ATORVASTATIN CALCIUM (Dr. Reddy's Laboratories)
Component
Amlodipine besilate [DR:D00615], (Atorvastatin calcium hydrate [DR:D02258] | Atorvastatin calcium [DR:D00887] | Atorvastatin calcium propylene glycol solvate [DR:D11095])
Class
Hypolipidemic agent
 DG01946  Hypolipidemic agent
Metabolizing enzyme substrate
 DG01633  CYP3A/CYP3A4 substrate
  DG02913  CYP3A4 substrate
Remark
Therapeutic category: 2190
ATC code: C10BX03
Product: D08488<JP/US>
Efficacy
Antihyperlipidemic, Antihypertensive
  Disease
Hypertension [DS:H01633]
Coronary artery disease [DS:H01742]
Chronic stable angina [DS:H01632]
Hyperlipidemia [DS:H01635]
Metabolism
Enzyme: CYP3A4 [HSA:1576]
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C10 LIPID MODIFYING AGENTS
   C10B LIPID MODIFYING AGENTS, COMBINATIONS
    C10BX Lipid modifying agents in combination with other drugs
     C10BX03 Atorvastatin and amlodipine
      D08488  Amlodipine besilate and atorvastatin calcium <JP/US>
USP drug classification [BR:br08302]
 Cardiovascular Agents
  Cardiovascular Agents, Combinations
   Amlodipine Besylate/ Atorvastatin Calcium
    D08488  Amlodipine besilate and atorvastatin calcium
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  21  Cardiovascular agents
   219  Miscellaneous
    2190  Miscellaneous
     D08488  Amlodipine besilate and atorvastatin calcium
Drug groups [BR:br08330]
 Hypolipidemic agent
  DG01946  Hypolipidemic agent
   D08488  Amlodipine besilate and atorvastatin calcium
 Metabolizing enzyme substrate
  DG01633  CYP3A/CYP3A4 substrate
   DG02913  CYP3A4 substrate
    D08488  Amlodipine besilate and atorvastatin calcium
Drug classes [BR:br08332]
 Cardiovascular agent
  DG01946  Hypolipidemic agent
   D08488  Amlodipine besilate and atorvastatin calcium
Drug metabolizing enzymes and transporters [br08309.html]
 Drug metabolizing enzymes
  D08488
Other DBs
PubChem: 96025174
LinkDB

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