KEGG   ORTHOLOGY: K04536
Entry
K04536                      KO                                     

Name
GNB1
Definition
guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
Pathway
ko04011  MAPK signaling pathway - yeast
ko04014  Ras signaling pathway
ko04062  Chemokine signaling pathway
ko04151  PI3K-Akt signaling pathway
ko04371  Apelin signaling pathway
ko04713  Circadian entrainment
ko04723  Retrograde endocannabinoid signaling
ko04724  Glutamatergic synapse
ko04725  Cholinergic synapse
ko04726  Serotonergic synapse
ko04727  GABAergic synapse
ko04728  Dopaminergic synapse
ko04740  Olfactory transduction
ko04744  Phototransduction
ko04926  Relaxin signaling pathway
ko05032  Morphine addiction
ko05034  Alcoholism
ko05163  Human cytomegalovirus infection
ko05167  Kaposi sarcoma-associated herpesvirus infection
ko05170  Human immunodeficiency virus 1 infection
ko05200  Pathways in cancer
Disease
H00773  Autosomal dominant mental retardation
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04011 MAPK signaling pathway - yeast
    K04536  GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
   04014 Ras signaling pathway
    K04536  GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
   04371 Apelin signaling pathway
    K04536  GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
   04151 PI3K-Akt signaling pathway
    K04536  GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
 09150 Organismal Systems
  09151 Immune system
   04062 Chemokine signaling pathway
    K04536  GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
  09152 Endocrine system
   04926 Relaxin signaling pathway
    K04536  GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
  09156 Nervous system
   04724 Glutamatergic synapse
    K04536  GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
   04727 GABAergic synapse
    K04536  GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
   04725 Cholinergic synapse
    K04536  GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
   04728 Dopaminergic synapse
    K04536  GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
   04726 Serotonergic synapse
    K04536  GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
   04723 Retrograde endocannabinoid signaling
    K04536  GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
  09157 Sensory system
   04744 Phototransduction
    K04536  GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
   04740 Olfactory transduction
    K04536  GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
  09159 Environmental adaptation
   04713 Circadian entrainment
    K04536  GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K04536  GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K04536  GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
   05163 Human cytomegalovirus infection
    K04536  GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
   05167 Kaposi sarcoma-associated herpesvirus infection
    K04536  GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
  09165 Substance dependence
   05032 Morphine addiction
    K04536  GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
   05034 Alcoholism
    K04536  GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K04536  GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
   04031 GTP-binding proteins
    K04536  GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   K04536  GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
  Exosomal proteins of colorectal cancer cells
   K04536  GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
  Exosomal proteins of melanoma cells
   K04536  GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
GTP-binding proteins [BR:ko04031]
 Heterotrimeric G-proteins
  Beta Subunits
   Beta [OT]
    K04536  GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
Other DBs
COG: COG2319
Genes
HSA: 2782(GNB1)
PTR: 469458(GNB1)
PPS: 100978523(GNB1)
GGO: 101154353(GNB1)
PON: 100173664(GNB1)
NLE: 100583137(GNB1)
MCC: 703399(GNB1)
MCF: 102120049(GNB1)
CSAB: 103225777(GNB1)
CATY: 105594434(GNB1)
RRO: 104653553(GNB1)
RBB: 108536033(GNB1)
TFN: 117093437(GNB1)
CJC: 100412968(GNB1)
SBQ: 101041488(GNB1)
MMUR: 105877661(GNB1)
MMU: 14688(Gnb1)
MCAL: 110292306(Gnb1)
MPAH: 110323886(Gnb1)
RNO: 24400(Gnb1)
MCOC: 116097142(Gnb1)
MUN: 110559917(Gnb1)
CGE: 100689442(Gnb1)
PLEU: 114708288(Gnb1)
NGI: 103749764(Gnb1)
HGL: 101703108(Gnb1)
CCAN: 109691437(Gnb1)
OCU: 100337783(GNB1)
TUP: 102482352(GNB1)
CFA: 403912(GNB1)
VVP: 112926168(GNB1)
AML: 100474825(GNB1)
UMR: 103682042(GNB1)
UAH: 113270618(GNB1)
ORO: 101381482(GNB1)
ELK: 111154601
MPUF: 101690759(GNB1)
EJU: 114213175(GNB1)
FCA: 101086580(GNB1)
PTG: 102950533(GNB1)
PPAD: 109273949(GNB1)
AJU: 106984654(GNB1)
BTA: 281201(GNB1)
BOM: 102270539(GNB1)
BIU: 109570386(GNB1)
BBUB: 102406849(GNB1)
CHX: 102187070(GNB1)
OAS: 101104166(GNB1)
SSC: 110261346(GNB1)
CFR: 102508170(GNB1)
CDK: 105105557(GNB1)
BACU: 103006513(GNB1)
LVE: 103069235(GNB1)
OOR: 101282575(GNB1)
DLE: 111187055(GNB1)
PCAD: 102986172(GNB1)
ECB: 100061395(GNB1)
EPZ: 103567413(GNB1)
EAI: 106845218(GNB1)
MYB: 102257321(GNB1)
MYD: 102764577(GNB1)
MMYO: 118655599(GNB1)
MNA: 107540160(GNB1)
HAI: 109391171(GNB1)
DRO: 112299038(GNB1)
SHON: 118998185(GNB1)
AJM: 119050543(GNB1)
MMF: 118643409(GNB1)
PALE: 102883771(GNB1)
RAY: 107510694(GNB1)
MJV: 108398173(GNB1)
LAV: 100673391(GNB1)
TMU: 101350742
MDO: 100010736(GNB1)
SHR: 100930507(GNB1)
PCW: 110200602(GNB1)
OAA: 100077049(GNB1)
GGA: 419402(GNB1)
MGP: 100539223(GNB1)
CJO: 107323292(GNB1)
NMEL: 110408654(GNB1)
APLA: 101803096(GNB1)
ACYG: 106044611(GNB1)
TGU: 100218759(GNB1)
LSR: 110470323(GNB1)
SCAN: 103820803(GNB1)
GFR: 102032629(GNB1)
FAB: 101815234(GNB1)
PHI: 102112205(GNB1)
PMAJ: 107213669(GNB1)
CCAE: 111938634(GNB1)
CCW: 104693300(GNB1)
ETL: 114063175(GNB1)
FPG: 101924451(GNB1)
FCH: 102046024(GNB1)
CLV: 102087608(GNB1)
EGZ: 104134563(GNB1)
NNI: 104008943(GNB1)
ACUN: 113487802(GNB1)
PADL: 103917927(GNB1)
AAM: 106485749(GNB1)
ASN: 102378181(GNB1)
AMJ: 102568881(GNB1)
PSS: 102461637(GNB1)
CMY: 102937681(GNB1)
CPIC: 101953229(GNB1)
ACS: 100564228(gnb1)
PVT: 110073309(GNB1)
PBI: 103059398(GNB1)
PMUR: 107290693(GNB1)
TSR: 106541288(GNB1)
PMUA: 114602545(GNB1)
GJA: 107116094(GNB1)
XLA: 108696545(gnb1.L) 399330(gnb1.S)
XTR: 448577(gnb1)
NPR: 108784330(GNB1)
DRE: 322104(gnb1a) 406796(gnb1b)
PHYP: 113530828 113533258(gnb1)
AMEX: 103023031 103044197(gnb1)
EEE: 113571588 113580458(gnb1)
TRU: 101062348 101066479(gnb1)
LCO: 104919476 104921446(gnb1)
MZE: 101480944(gnb1) 101487059
ONL: 100699333(gnb1) 100703896
OLA: 100049498(ol-gb1) 101168199
XMA: 102220768 102227680(gnb1)
XCO: 114135385 114142780(gnb1)
PRET: 103464516 103467036(gnb1)
CVG: 107088190(gnb1) 107089355
NFU: 107385217 107390330(gnb1)
KMR: 108231344(gnb1b) 108233109(gnb1a)
ALIM: 106516123 106518944(gnb1)
AOCE: 111564732(gnb1) 111579901
CSEM: 103384771(gnb1) 103385643
POV: 109630799(gnb1) 109638561
LCF: 108882582(gnb1) 108899241
SDU: 111222841 111237029(gnb1)
SLAL: 111653826 111656191(gnb1)
HCQ: 109507118 109511744(gnb1)
MALB: 109959036 109967164(gnb1)
SASA: 106565997 106566880(GBB1) 106571997(GBB1) 106582769(GBB1)
ELS: 105013686(gnb1) 105025424
SFM: 108931087(gnb1) 108933763
PKI: 111834349(gnb1) 111858901
LCM: 102367354(GNB1)
CMK: 103187667(gnb1)
RTP: 109911846(gnb1)
CIN: 100182745
SPU: 590203
APLC: 110976474
SKO: 100375948
DME: Dmel_CG10545(Gbeta13F)
DER: 6550691
DSE: 6619996
DSI: Dsimw501_GD17247(Dsim_GD17247)
DAN: 6503209
DSR: 110184395
DPE: 6603559
DWI: 6652987
DAZ: 108620361
DNV: 108657919
DHE: 111596523
DVI: 6636518
MDE: 101887227
LCQ: 111682998
AME: 410497
BIM: 100745642
BTER: 100642300
CCAL: 108627888
OBB: 114874384
SOC: 105196793
MPHA: 105837922
AEC: 105151523
ACEP: 105623873
PBAR: 105426325
VEM: 105566845
HST: 105188698
DQU: 106743929
CFO: 105251133
LHU: 105669814
PGC: 109856275
OBO: 105284541
PCF: 106793947
NVI: 100114198
CSOL: 105366540
MDL: 103578498
TCA: 658674
DPA: 109542129
ATD: 109600178
NVL: 108565667
BMOR: 733012
BMAN: 114253446
PMAC: 106707737
PRAP: 111004296
HAW: 110379034
TNL: 113496053
PXY: 105388661
API: 100168225
DNX: 107169763
AGS: 114118998
RMD: 113548365
BTAB: 109036618
CLEC: 106662232
ZNE: 110832278
FCD: 110845887
DPX: DAPPUDRAFT_206575(Gnb1)
PVM: 113803885
TUT: 107368326
CSCU: 111614076
PTEP: 107455867
CEL: CELE_F13D12.7(gpb-1)
CBR: CBG03131(Cbr-gpb-1)
TSP: Tsp_02729
PCAN: 112556713
CRG: 105322341
MYI: 110461099
OBI: 106878845
LAK: 106175130
EPA: 110247759
ADF: 107338476
AMIL: 114961918
PDAM: 113664223
DGT: 114518103
HMG: 100214847
AQU: 100633901
ATH: AT4G34460(AGB1)
ALY: 9303191
CRB: 17877798
CPAP: 110813734
CIT: 102608071
TCC: 18607793
EGR: 104418830
VRA: 106756081
VAR: 108340218
VUN: 114169926
CAM: 101495136
LJA: Lj0g3v0235829.1(Lj0g3v0235829.1) Lj1g3v3407660.1(Lj1g3v3407660.1) Lj3g3v3338610.1(Lj3g3v3338610.1)
FVE: 101297832
RCN: 112172926
PPER: 18767499
PMUM: 103335641
ZJU: 107426919
CSV: 101218729
CMO: 103489586
MCHA: 111007811
RCU: 8271413
JCU: 105632182
VVI: 100853292
SLY: 101252441
SPEN: 107006105
SOT: 102577705(GB2)
CANN: 107850285(Gbeta2)
OEU: 111380705
CCAV: 112516637
BVG: 104904365
SOE: 110805508
OSA: 4333680
DOSA: Os03t0669200-01(Os03g0669200)
OBR: 102707755
BDI: 100823844
ATS: 109766718
SBI: 8054193
ZMA: 542310(gbp2)
SITA: 101775384
DCT: 110115474
PEQ: 110030369
ATR: 18445842
SMO: SELMODRAFT_142121(AGB1-1) SELMODRAFT_440157(AGB1-2)
PPP: 112278789
SCE: YOR212W(STE4)
ERC: Ecym_8317
KMX: KLMA_20806(STE4)
NCS: NCAS_0B01660(NCAS0B01660)
NDI: NDAI_0E01500(NDAI0E01500)
TPF: TPHA_0G01840(TPHA0G01840)
TBL: TBLA_0B04070(TBLA0B04070)
TDL: TDEL_0A05770(TDEL0A05770)
KAF: KAFR_0G01970(KAFR0G01970)
CAL: CAALFM_C204210WA(STE4)
NCR: NCU00440(gnb-1)
NTE: NEUTE1DRAFT117080(NEUTE1DRAFT_117080)
MGR: MGG_05201
SSCK: SPSK_07459
TRE: TRIREDRAFT_46469(tgb1)
MAW: MAC_01638
MAJ: MAA_02470
BFU: BCIN_08g01420(Bcgb1)
MBE: MBM_01115
ANI: AN0081.2
ANG: ANI_1_248164(An18g02090)
ABE: ARB_04406
TVE: TRV_04826
PTE: PTT_17426
ZTR: MYCGRDRAFT_68892(MgGpb1)
SPO: SPBC32H8.07(git5)
CNE: CND03830
CNB: CNBD2480
TASA: A1Q1_01784
ABP: AGABI1DRAFT81726(AGABI1DRAFT_81726)
ABV: AGABI2DRAFT132917(AGABI2DRAFT_132917)
MGL: MGL_1772
MRT: MRET_2046
DDI: DDB_G0277143(gpbA)
DFA: DFA_09646(gpbA)
EHI: EHI_000240(106.t00026)
 » show all
Reference
PMID:8995254
  Authors
Hirschman JE, De Zutter GS, Simonds WF, Jenness DD
  Title
The G beta gamma complex of the yeast pheromone response pathway. Subcellular fractionation and protein-protein interactions.
  Journal
J Biol Chem 272:240-8 (1997)
DOI:10.1074/jbc.272.1.240
Reference
PMID:3095147
  Authors
Codina J, Stengel D, Woo SL, Birnbaumer L
  Title
Beta-subunits of the human liver Gs/Gi signal-transducing proteins and those of bovine retinal rod cell transducin are identical.
  Journal
FEBS Lett 207:187-92 (1986)
DOI:10.1016/0014-5793(86)81486-7
  Sequence
[hsa:2782]
LinkDB

DBGET integrated database retrieval system