KEGG ORTHOLOGY: K05404

ORTHOLOGY: K05404

Entry

K05404                      KO

Symbol

TLR7

Name

toll-like receptor 7

Pathway

map04613

Neutrophil extracellular trap formation

map04620

Toll-like receptor signaling pathway

map05162

Measles

map05164

Influenza A

map05171

Coronavirus disease - COVID-19

Disease

H00080

Systemic lupus erythematosus

H00096

Defects of toll-like receptor signaling

Brite

KEGG Orthology (KO) [BR:ko00001]
09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    K05404  TLR7; toll-like receptor 7
   04620 Toll-like receptor signaling pathway
    K05404  TLR7; toll-like receptor 7
09160 Human Diseases
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    K05404  TLR7; toll-like receptor 7
   05164 Influenza A
    K05404  TLR7; toll-like receptor 7
   05162 Measles
    K05404  TLR7; toll-like receptor 7
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04054 Pattern recognition receptors
    K05404  TLR7; toll-like receptor 7
Pattern recognition receptors [BR:ko04054]
Membrane-bound pattern recognition receptors
  Toll-like receptors
   K05404  TLR7; toll-like receptor 7

Genes

HSA:	51284(TLR7)

PTR:	473521(TLR7)

PPS:	100986249(TLR7)

GGO:	101151944(TLR7)

PON:	100460366(TLR7)

PPYG:

129023862(TLR7)

NLE:	100585813(TLR7)

HMH:	116811520(TLR7)

SSYN:

129475151(TLR7)

MCC:	574291(TLR7)

MCF:	102139628(TLR7)

MTHB:

126946660

MNI:	105478130(TLR7)

CSAB:

103231601(TLR7)

CATY:

105574716(TLR7)

PANU:

101020343(TLR7)

TGE:	112615894(TLR7)

MLEU:

105550032(TLR7)

RRO:	104678074(TLR7)

RBB:	108520706(TLR7)

TFN:	117077597(TLR7)

PTEH:

111531682(TLR7)

CANG:

105518050(TLR7)

CJC:	100398462(TLR7)

SBQ:	101035195(TLR7)

CIMI:

108289374(TLR7)

ANAN:

105705328(TLR7)

CSYR:

103275031(TLR7)

MMUR:

105882440(TLR7)

LCAT:

123627997(TLR7)

ERUF:

138378366(TLR7)

PCOQ:

105820964(TLR7)

OGA:	100965410(TLR7)

MMU:	170743(Tlr7)

MCAL:

110287296(Tlr7)

MPAH:

110313948(Tlr7)

RNO:	317468(Tlr7)

MCOC:

116090574(Tlr7)

ANU:	117694755(Tlr7)

ASYL:

127674803(Tlr7)

MUN:	110566562(Tlr7)

CGE:	100767608(Tlr7)

MAUA:

101840275(Tlr7)

PROB:

127214478(Tlr7)

PLEU:

114702940(Tlr7)

PMAV:

102909239(Tlr7)

MORG:

121439389(Tlr7) 121444439

MFOT:

126487960

AAMP:

119804959(Tlr7)

NGI:	103749969(Tlr7)

HGL:	101705918(Tlr7)

CPOC:

100713329(Tlr7)

CCAN:

109701083(Tlr7)

DORD:

105997681(Tlr7)

DSP:	122108540(Tlr7)

DMER:

138840495(Tlr7)

PLOP:

125343440(Tlr7)

NCAR:

124971905

MMMA:

107144227(Tlr7)

ITI:	101956402(Tlr7)

OPI:	101518520 101534566(TLR7)

OCZ:	121153075(TLR7)

TUP:	102467662(TLR7)

GVR:	103589376(TLR7)

CFA:	491743(TLR7)

CLUD:

112652898(TLR7)

VVP:	112932376(TLR7)

VLG:	121482726(TLR7)

NPO:	129518283(TLR7)

AML:	100467398(TLR7)

UMR:	103668101(TLR7)

UAH:	113240728(TLR7)

UAR:	123786491(TLR7)

ELK:

111157097

LLV:

125092074

MPUF:

101685809

MNP:	132007221(TLR7)

MLK:	131820747(TLR7)

NVS:	122897207(TLR7)

ORO:	101370150(TLR7)

EJU:	114218118(TLR7)

ZCA:	113931554(TLR7)

MLX:	118026716(TLR7)

NSU:	110575092(TLR7)

LWW:	102744012(TLR7)

FCA:	493685(TLR7)

PYU:	121025163(TLR7)

PCOO:

112871667(TLR7)

PBG:	122477209(TLR7)

PVIV:

125157872(TLR7)

LRUF:

124509347

LGF:	123594661(TLR7)

AJU:

106971060

PTG:	102964938(TLR7)

PPAD:

109248292(TLR7)

PUC:

125931478

HHV:	120233135(TLR7)

BTA:	493686(TLR7)

BOM:	102281602(TLR7)

BIU:	109555486(TLR7)

BBUB:

102409386(TLR7)

CHX:	102171227(TLR7)

OAS:	554254(TLR7)

BTAX:

128070301(TLR7)

CSUM:

138071194(TLR7)

ODA:	120882452(TLR7)

CCAD:

122435292(TLR7)

MREE:

136153422(TLR7)

OVR:	110147394(TLR7)

MBEZ:

129535062(TLR7)

SSC:	100037296(TLR7)

CFR:	102518723(TLR7)

CBAI:

105077753(TLR7)

CDK:	105100614(TLR7)

VPC:	102541655(TLR7)

BACU:

103018679(TLR7)

BMUS:

118888620(TLR7)

LVE:	103082846(TLR7)

OOR:	101287353(TLR7)

LALB:

132512922(TLR7)

GMF:	115846460(TLR7)

DDP:	132418413(TLR7)

DLE:	111167211(TLR7)

PCAD:

102990770(TLR7)

PSIU:

116747688(TLR7)

PPHC:

136142524(TLR7)

NASI:

112409740(TLR7)

ECB:	791248(TLR7)

EPZ:	103542844(TLR7)

EAI:	106848661(TLR7)

MYB:	102258183(TLR7)

MYD:	102771636(TLR7)

MMYO:

118654568(TLR7)

MLF:	102428265(TLR7)

MDT:	132223823(TLR7)

PKL:	118719932(TLR7)

EFUS:

103299728(TLR7)

MNA:	107539214(TLR7)

DRO:	112313330(TLR7)

SHON:

118987227(TLR7)

AJM:	119058368(TLR7)

PDIC:

114505233(TLR7)

PHAS:

123830141(TLR7)

MMF:	118636314(TLR7)

PPAM:

129076961(TLR7)

HAI:	109387359(TLR7)

RFQ:	117029119(TLR7)

PALE:

102894711(TLR7)

PGIG:

120611402(TLR7)

PVP:	105293980(TLR7)

RAY:	107497585(TLR7)

MJV:	108397208(TLR7)

TOD:	119246342(TLR7)

SARA:

101555293(TLR7)

SFUM:

130039352(TLR7)

SETR:

125999107(TLR7)

LAV:	100668932(TLR7)

TMU:

101348713

ETF:	101642583(TLR7)

DNM:	101433863(TLR7)

MDO:	100617460(TLR7)

GAS:	123239684(TLR7)

SHR:	100923338(TLR7)

AFZ:

127553639

PCW:	110222480(TLR7)

TVP:	118835570(TLR7)

PBRV:

138142061(TLR7)

MLAO:

141491464(TLR7)

OAA:	100084796(TLR7)

TACU:

119937569(TLR7)

GGA:	418638(TLR7)

PCOC:

116230739

MGP:

100542671

CJO:	107325922(TLR7)

TPAI:

128071693(TLR7)

LMUT:

125685402(TLR7)

NMEL:

110405302(TLR7)

APLA:

101797264(TLR7)

AACU:

137857020(TLR7)

ACYG:

106042570(TLR7)

CATA:

118245755(TLR7)

AFUL:

116495507(TLR7)

TGU:	100231797 115496483

LSR:	110469812(TLR7)

SCAN:

103815911(TLR7) 103815912

PMOA:

120504723(TLR7)

OTC:	121342233(TLR7)

PRUF:

121356162 121356163 121356271

ATRC:

139591667 139591668(TLR7)

GFR:	102040693 102044095 102044263(TLR7) 106632034

FAB:	101811877 101820445(TLR7)

OMA:	130258848 130258856(TLR7)

PHI:	102104620 102112976(TLR7)

PMAJ:

107205471(TLR7) 107208524

CCAE:

111922815

CCW:	104686149 104686150(TLR7)

CBRC:

103611747 103611748

ACOE:

138117997 138118003(TLR7)

ETL:	114068933 114068934(TLR7)

ZAB:

102072608

ZLE:	135445953 135446007

SVG:	106864674(TLR7)

MMEA:

130585495 130588546(TLR7)

HRT:	120748872 120749375

SATI:

136358051 136358052

CCIC:

134058044 134058045

FPG:	101922221(TLR7)

FCH:	102053276(TLR7)

CCRI:

104156808(TLR7)

NNT:	104409939(TLR7)

SHAB:

115603144(TLR7)

ACUN:

113484122(TLR7)

SURA:

141939316 141939317

TALA:

116958811 116964893

ACHC:

115334697

HALD:

104312358(TLR7)

HLE:	104840564(TLR7)

AGEN:

126052989

HHAR:

128135074(TLR7)

BBUT:

142044722(TLR7)

GCL:

127029928

CSTI:

104550442(TLR7)

LDI:	104340732(TLR7)

MNB:	103768136(TLR7)

DPUB:

104297072

PPUS:

135175603

BRHI:

104497297(TLR7)

EGZ:	104132980(TLR7)

NNI:	104022546(TLR7)

PCRI:

104026425(TLR7)

PCAO:

104039919(TLR7)

PADL:

103912579(TLR7)

AFOR:

103898291

FGA:	104072787(TLR7)

CBOR:

142094260(TLR7)

GSTE:

104258555(TLR7)

CBOY:

140647823(TLR7)

MAME:

142404902(TLR7)

CLV:	102093882(TLR7)

CNIC:

135991367 135991431

PGUU:

104460421(TLR7)

PLET:

104614343(TLR7)

EHS:	104505242(TLR7)

CMAC:

104479255(TLR7)

CUCA:

104054228 104054906

TEO:	104382966(TLR7)

BREG:

104630052(TLR7)

GAME:

129201673(TLR7)

OHA:

104337542

ACAR:

104530613(TLR7)

CPEA:

104398668

CVF:	104293787 104295450

RTD:	128903648 128904326(TLR7)

CRID:

134518675 134518684

LMIC:

141750734 141750738

AAM:	106490995(TLR7)

AROW:

112964611

NPD:	112954160(TLR7)

TGT:	104580785(TLR7)

DNE:	112993233(TLR7)

SCAM:

104149808(TLR7)

ASN:	102375604(TLR7)

AMJ:	106736663(TLR7)

CPOO:

109306066(TLR7)

GGN:	109303433(TLR7)

PSS:	102444127 102455967(TLR7)

CIZ:	142012517(TLR7)

CMY:	102948199(TLR7)

CCAY:

125630473(TLR7)

LKP:	140904880(TLR7)

NDS:

141983110

DCC:	119860284(TLR7)

CPIC:

101940183 101946991(TLR7)

TST:	117869894(TLR7)

CABI:

116825972(TLR7) 116831947

MRV:	120396137(TLR7)

ACS:	100563333(tlr7)

ASAO:

132771671

PVT:

110075448

SUND:

121927255(TLR7)

PBI:	103054114(TLR7)

PMUR:

107302471(TLR7)

CTIG:

120306497

TSR:	106557432(TLR7)

PGUT:

117676120

PCAE:

139316425

APRI:

131199829(TLR7)

PTEX:

113445185

NSS:

113411750

VKO:	123024449(TLR7)

PMUA:

PRAF:

ZVI:

HCG:

GJA:	107124266(TLR7)

STOW:

125431652(TLR7)

EMC:

129326129

XLA:	100049730(tlr9.L) 108708382

XTR:	100151703(tlr7) 100494387(tlr9)

NPR:	108794923 108794925

RTEM:

120926525 120944982 120945990

ACAT:

141102840 141102841 141102843 141127946

PADS:

140333036(TLR7) 140336882

BBUF:

120979521

BGAR:

122922659

PWL:	138250169 138259248

MUO:	115469189(TLR7)

GSH:	117351405 117362922(TLR7)

SRX:	107707567 107716601

SANH:

107679937 107691260

SGH:	107563880 107564304(tlr7)

CCAR:

109113714(tlr7) 122146173

CAUA:

113052898 113108208

CGIB:

127964769 128020230

PTET:

122333056(tlr7)

LROH:

127170549(tlr7)

GRF:	141341009(tlr7)

OMC:	131546816(tlr7)

PPRM:

120479181(tlr7)

RKG:	130072551(tlr7)

MAMB:

125270860(tlr7)

CIDE:

127518375

CERY:

137035347(tlr7)

MASI:

127446972 127448224

TROS:

130556130(tlr7)

TDW:	130427117(tlr7)

MANU:

129451747(tlr7)

PDAB:

135733625(tlr7)

IPU:

108266215

IFU:	128609268(tlr7)

PHYP:

113524315(tlr7)

SMEO:

124379398(tlr7)

TFD:	113642083(tlr7)

TVC:	132849776(tlr7)

CGAR:

128524705(tlr7)

NGRA:

132896430(tlr7)

TRN:	134324045(tlr7)

AMEX:

103027598(tlr7)

CMAO:

118811342(tlr7)

EEE:	113588862(tlr7)

CHAR:

105898069(tlr7)

SPIL:

134077817(tlr7)

ASAD:

121702210(tlr7)

TRU:

101074686

TFS:	130530546(tlr9) 130540054(tlr7)

TNG:	GSTEN00026075G001

LCO:	104928705 104931721

NCC:	104946407 104947493(tlr7)

TBEN:

117481095(tlr7) 117494240(tlr9)

CGOB:

115011076 115026585

PGEO:

117449150(tlr9) 117466508(tlr7)

GACU:

117540703(tlr9) 117544385(tlr7)

EMAC:

134866370(tlr9) 134867067(tlr7)

ELY:	117249639(tlr7) 117258821(tlr9)

EFO:	125892461(tlr9) 125900269(tlr7)

PLEP:

121946727(tlr9) 121948920(tlr7)

SLUC:

116047490(tlr7) 116061966(tlr9)

ECRA:

117948157(tlr9) 117952485(tlr7)

ESP:	116692949 116697960

PFLV:

114559444 114563879

GAT:	120829837(tlr9) 120833811(tlr7)

PPUG:

119223414(tlr9) 119229230(tlr7)

AFB:	129099715(tlr9) 129104153(tlr7)

CLUM:

117733169(tlr9) 117750009(tlr7)

PSWI:

130207490(tlr7)

CANA:

137782630(tlr7) 137799816(tlr9)

CVE:	137868204(tlr7) 137889084(tlr9)

MSAM:

119904157(tlr7) 119905438(tlr9)

SCHU:

122882454(tlr9) 122885971(tlr7)

CUD:	121517622(tlr9) 121522771(tlr7)

SPUL:

138589461(tlr9) 138592257(tlr7)

LMIX:

132987484(tlr7) 132989278(tlr9)

HTC:	141799233(tlr9) 141808096

ALAT:

119022256(tlr9) 119025628(tlr7)

ASTR:

137601921 137604681(tlr7) 137610496

MZE:

101469110

ONL:	100696189 109194414(tlr7)

OAU:	116319304(tlr7) 116330782(tlr9)

OLA:	101160555 101169500

OML:	112154903(tlr7) 112158934(tlr9)

CSAI:

133445894(tlr7) 133457123(tlr9)

XMA:	102220828 102229065

XCO:	114144965 114148005

XHE:	116723026 116727865

PRET:

103459167 103467449

PFOR:

103129854 103134242

PLAI:

106954792(tlr7) 106959472

PMEI:

106930118 106934214

GAF:	122833656(tlr9) 122839958(tlr7)

PPRL:

129361302(tlr7) 129370195(tlr9)

CVG:

107094851

CTUL:

119784329(tlr9) 119788778(tlr7)

GMU:	124865411(tlr9) 124871606(tlr7)

NFU:	107373673 107389944(tlr7)

KMR:	108235265(tlr9) 108239750(tlr7)

ALIM:

106522631 106524764(tlr7)

NWH:	119417588(tlr9) 119419639(tlr7)

AOCE:

111574392(tlr9) 111583414(tlr7)

EJA:	138192955(tlr9) 138200926(tlr7)

BFRE:

138623260(tlr7) 138636993(tlr9)

MCEP:

125017183(tlr7) 125018774

CSEM:

103392029(tlr7)

POV:	109631070 109635251

SSEN:

122776703(tlr9) 122786174(tlr7)

SSOE:

131443477(tlr7) 131468353(tlr9)

HHIP:

117755076(tlr7) 117764696(tlr9)

HSP:	118111008(tlr9) 118120441(tlr7)

PPLT:

128442937(tlr9) 128455820(tlr7)

SMAU:

118282534(tlr7) 118316405(tlr9)

LCF:	108877869 108901560(tlr7)

SDU:	111218812 111218988

SLAL:

111662164 111668980

XGL:	120801675(tlr7) 120804034(tlr9)

HCQ:

109531307

SSCV:

125973618(tlr7)

SBIA:

133512449(tlr7)

PEE:	133410385(tlr7)

PTAO:

133486812(tlr7)

BPEC:

110173148

ENY:	140359581(tlr7) 140363327(tlr9)

MALB:

109958106 109968743

BSPL:

114846766(tlr7) 114858465(tlr9)

SJO:	128357604(tlr9) 128368174(tlr7)

SSCO:

133987587(tlr9) 133992587(tlr7)

TTY:	137192761(tlr7)

GMH:	115528735 115533264 115546259 115549215 115551811

SASA:

100136557(tlr9) 106586812(TLR7)

STRU:

115161349(tlr7) 115168543

OTW:	112222359(tlr9) 112242814(tlr7)

OMY:	100170212(tlr9) 110520615(tlr7)

OGO:	124044255 124045575(tlr9)

ONE:	115101983 115113533(tlr7)

OKI:	109868967 109870899(tlr7)

OKE:	118359575(tlr9) 118366580(tlr7)

OMM:	135518952(tlr7) 135527843(tlr9)

OCLA:

139368899 139406177

SALP:

112068358(tlr7) 112075520

SNH:	120058137(tlr7) 120061447(tlr9)

SFON:

129820845(tlr7) 129861220(tlr9)

CCLU:

121536465(tlr7) 121546798(tlr9)

ELS:

105018780

OEP:	134016936(tlr7)

SFM:	108920458(tlr7)

PKI:	111851505(tlr7)

AANG:

118208268(tlr9) 118213765(tlr7)

AROT:

135234091(tlr9) 135241364(tlr7)

CCOG:

133116276 133138620(tlr9)

LOC:	107077431(tlr9) 107079175(tlr7)

PSPA:

121298377(tlr9) 121321029 121327655

ARUT:

117407403(tlr7) 117412533 117963561

PSEX:

120522878(tlr7)

LCM:	102347513(TLR7) 102356471

CMK:	103176640 103177464(tlr7)

RTP:	109920606(tlr7) 109920613 109937187(tlr9)

CPLA:

122555017 122555018(tlr7) 122558837(tlr9)

CPUN:

140483468(tlr9) 140486159 140486163(tlr7)

HOC:	132820909(tlr7) 132821007 132822452(tlr9)

SCAU:

119969192 119973831(tlr9)

LERI:

129704712

HAKA:

140727885(tlr7) 140742005(tlr9)

PMRN:

116954901

LRJ:	133347792 133351488

CLEP:

143445391 143448240 143449892 143450180 143450279 143452667 143452668 143453037 143461161 143462856 143465084 143468263

PVUL:

HRJ:

CANU:

RPHI:

Reference

PMID:16410796

Authors

Kawai T, Akira S

Title

TLR signaling.

Journal

Cell Death Differ 13:816-25 (2006)
DOI:10.1038/sj.cdd.4401850

Reference

PMID:11022119

Authors

Du X, Poltorak A, Wei Y, Beutler B

Title

Three novel mammalian toll-like receptors: gene structure, expression, and evolution.

Journal

Eur Cytokine Netw 11:362-71 (2000)

Sequence

[hsa:51284]

LinkDB

DBGET integrated database retrieval system