KEGG ORTHOLOGY: K09442

ORTHOLOGY: K09442

Entry

K09442                      KO

Symbol

SPDEF

Name

SAM pointed domain-containing ETS transcription factor

Pathway

map04361

Axon regeneration

Brite

KEGG Orthology (KO) [BR:ko00001]
09150 Organismal Systems
  09158 Development and regeneration
   04361 Axon regeneration
    K09442  SPDEF; SAM pointed domain-containing ETS transcription factor
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K09442  SPDEF; SAM pointed domain-containing ETS transcription factor
Transcription factors [BR:ko03000]
Eukaryotic type
  Helix-turn-helix
   Tryptophan clusters Ets-type
    K09442  SPDEF; SAM pointed domain-containing ETS transcription factor

Genes

HSA:	25803(SPDEF)

PTR:	462627(SPDEF)

PPS:	130540449(SPDEF)

GGO:	101134344(SPDEF)

PON:	100440076(SPDEF)

PPYG:

129038560(SPDEF)

NLE:	100580686(SPDEF)

HMH:	116460123(SPDEF)

SSYN:

129473495(SPDEF)

MCC:	718648(SPDEF)

MCF:	102137858(SPDEF)

MTHB:

126952782

MNI:	105474484(SPDEF)

CSAB:

103221630(SPDEF)

CATY:

105593085(SPDEF)

PANU:

101007283(SPDEF)

TGE:	112623693(SPDEF)

MLEU:

105544196(SPDEF)

RRO:	104658129(SPDEF)

RBB:	108516269(SPDEF)

TFN:	117087077(SPDEF)

PTEH:

111542939(SPDEF)

CANG:

105514204(SPDEF)

CJC:	100395790(SPDEF)

SBQ:	101027811(SPDEF)

CIMI:

108299788(SPDEF)

ANAN:

105723539(SPDEF)

CSYR:

103269247(SPDEF)

MMUR:

105861360(SPDEF)

LCAT:

123632834(SPDEF)

PCOQ:

105812209(SPDEF)

OGA:	100946723(SPDEF)

MMU:	30051(Spdef)

MCAL:

110284310(Spdef)

MPAH:

110338401(Spdef)

RNO:	689210(Spdef)

MCOC:

116074752(Spdef)

ANU:	117724809(Spdef)

ASYL:

127669587(Spdef)

MUN:	110543006(Spdef)

CGE:	100756355(Spdef)

MAUA:

101841666(Spdef)

PROB:

127224242(Spdef)

PLEU:

114706170(Spdef)

MORG:

121435486(Spdef)

MFOT:

126500943

AAMP:

119824019(Spdef)

NGI:	103739683(Spdef)

HGL:	101698462(Spdef)

CPOC:

100726493(Spdef)

CCAN:

109686683(Spdef)

DORD:

105995769(Spdef)

DSP:	122111472(Spdef)

PLOP:

125352183(Spdef)

NCAR:

124989045

MMMA:

107143609(Spdef)

ITI:	101971667(Spdef)

OCU:

100356980

OPI:	101519697(SPDEF)

TUP:	102488752(SPDEF)

GVR:	103595161(SPDEF)

CFA:	481751(SPDEF)

CLUD:

112641447(SPDEF)

VVP:	112914202(SPDEF)

VLG:	121490892(SPDEF)

NPO:	129512746(SPDEF)

AML:	100468397(SPDEF)

UMR:	103665549(SPDEF)

UAH:	113243667(SPDEF)

UAR:	123776218 123791044(SPDEF)

ELK:

111152508

LLV:

125103197

MPUF:

101670206(SPDEF)

MNP:	132017203(SPDEF)

MLK:	131834219(SPDEF)

NVS:	122899828(SPDEF)

ORO:	101384080(SPDEF)

EJU:	114222101(SPDEF)

ZCA:	113927267(SPDEF)

MLX:	118001331(SPDEF)

NSU:	110575602(SPDEF)

LWW:	102749367(SPDEF)

FCA:	101096315(SPDEF)

PYU:	121029321(SPDEF)

PCOO:

112862844(SPDEF)

PBG:	122489435(SPDEF)

PVIV:

125166732(SPDEF)

LRUF:

124528002

LGF:	123608275(SPDEF)

AJU:

106976070

PTG:	102971704(SPDEF)

PPAD:

109271481(SPDEF)

PUC:

125938341

PLEZ:

122218988(SPDEF)

HHV:	120238201(SPDEF)

BTA:	497620(SPDEF)

BOM:	102275687(SPDEF)

BIU:	109577372(SPDEF)

BBUB:

102412002(SPDEF)

BBIS:

104995005(SPDEF)

CHX:	102185880(SPDEF)

OAS:	101120201(SPDEF)

BTAX:

128056731(SPDEF)

CSUM:

138069717(SPDEF)

ODA:	120869812(SPDEF)

CCAD:

122429952(SPDEF)

MREE:

136151883(SPDEF)

OVR:	110134314(SPDEF)

MBEZ:

129543389(SPDEF)

SSC:	100153013(SPDEF)

CFR:	102511138(SPDEF)

CBAI:

105064198(SPDEF)

CDK:	105101362(SPDEF)

VPC:	102524916(SPDEF)

BACU:

103017874(SPDEF)

BMUS:

118903919(SPDEF)

LVE:	103077104(SPDEF)

OOR:	101277181(SPDEF)

LALB:

132528114(SPDEF)

DLE:	111178706(SPDEF)

PCAD:

102992552(SPDEF)

PSIU:

116762510(SPDEF)

NASI:

112414018(SPDEF)

ECB:	100053106(SPDEF)

EPZ:	103557768(SPDEF)

EAI:	106834574(SPDEF)

MYB:	102240297(SPDEF)

MYD:	102758784(SPDEF)

MMYO:

118660491(SPDEF)

MLF:	102437151(SPDEF)

MDT:	132237434(SPDEF)

MYUM:

139013256(SPDEF)

PKL:	118706115(SPDEF)

EFUS:

103295531(SPDEF)

MNA:	107545583(SPDEF)

DRO:	112302125(SPDEF)

SHON:

118991515(SPDEF)

AJM:	119041238(SPDEF)

PDIC:

114494489(SPDEF)

PHAS:

123815793(SPDEF)

MMF:	118621945(SPDEF)

PPAM:

129066999(SPDEF)

HAI:	109392431(SPDEF)

RFQ:	117015951(SPDEF)

PALE:

102881181(SPDEF)

PGIG:

120597628(SPDEF)

PVP:	105301045(SPDEF)

RAY:	107511956(SPDEF)

MJV:	108398808(SPDEF)

TOD:	119253290(SPDEF)

SARA:

101558006(SPDEF)

SFUM:

130040503(SPDEF)

SETR:

125996330(SPDEF)

LAV:	100657870(SPDEF)

TMU:

101357433

ETF:	101661280(SPDEF)

DNM:	101442188(SPDEF)

MDO:	100025841(SPDEF)

GAS:	123247345(SPDEF)

SHR:	100919862(SPDEF)

AFZ:

127561161

PCW:	110217316(SPDEF)

TVP:	118855760(SPDEF)

PBRV:

138150109(SPDEF)

OAA:	100076627(SPDEF)

TACU:

119930979(SPDEF)

GGA:	428271(SPDEF)

PCOC:

116237089(SPDEF)

MGP:	104914526(SPDEF)

CJO:	107324876(SPDEF)

TPAI:

128088116(SPDEF)

LMUT:

125684038(SPDEF)

NMEL:

110388311(SPDEF)

APLA:

101805431(SPDEF)

ACYG:

106046125(SPDEF)

CATA:

118259547(SPDEF)

AFUL:

116498944(SPDEF)

TGU:	100219264(SPDEF)

LSR:	110473448(SPDEF)

PMOA:

120495935(SPDEF)

OTC:	121348037(SPDEF)

PRUF:

121353765(SPDEF)

ATRC:

139601161(SPDEF)

GFR:	102040065(SPDEF)

FAB:	101807724(SPDEF)

OMA:	130263798(SPDEF)

PHI:	102111595(SPDEF)

PMAJ:

107214884(SPDEF)

CCAE:

111939666(SPDEF)

CCW:	120411279(SPDEF)

CBRC:

103625360(SPDEF)

ACOE:

138098987(SPDEF)

ETL:	114064077(SPDEF)

ZAB:	102072904(SPDEF)

ZLE:	135458014(SPDEF)

SVG:	106851028(SPDEF)

MMEA:

130582636(SPDEF)

HRT:	120762889(SPDEF)

SATI:

136371706(SPDEF)

CCIC:

134054087(SPDEF)

FPG:	101925014(SPDEF)

FCH:	102056350(SPDEF)

NNT:	104413841(SPDEF)

SHAB:

115602201(SPDEF)

ACUN:

113488917(SPDEF)

TALA:

116965551(SPDEF)

ACHC:

115334829(SPDEF)

HLE:	104842370(SPDEF)

AGEN:

126052357

HHAR:

128154797(SPDEF)

GCL:

127026344

CSTI:

104559305(SPDEF)

LDI:	104348198(SPDEF)

DPUB:

104305376(SPDEF)

PPUS:

135191370(SPDEF)

BRHI:

104502294(SPDEF)

EGZ:	104125770(SPDEF)

NNI:	104013174(SPDEF)

AFOR:

103893717(SPDEF)

CBOY:

140643271(SPDEF)

CLV:	102085776(SPDEF)

MUI:	104533151(SPDEF)

PLET:

104622033(SPDEF)

CUCA:

104064929(SPDEF)

TEO:	104373873(SPDEF)

OHA:	104328927(SPDEF)

ACAR:

104528342(SPDEF)

CPEA:

104397176(SPDEF)

CVF:	104289383(SPDEF)

RTD:	128900299(SPDEF)

CRID:

134525558(SPDEF)

AAM:	106490931(SPDEF)

AROW:

112961407(SPDEF)

NPD:	112959143(SPDEF)

DNE:	112990274(SPDEF)

ASN:	102382148(SPDEF)

AMJ:	102570203(SPDEF)

CPOO:

109317707(SPDEF)

GGN:	109295431(SPDEF)

PSS:	102448230(SPDEF)

CMY:	102937815(SPDEF)

CCAY:

125625036(SPDEF)

DCC:	119846182(SPDEF)

CPIC:

101951106(SPDEF)

TST:	117876843(SPDEF)

CABI:

116832126(SPDEF)

MRV:	120402836(SPDEF)

ACS:	100563078(spdef)

ASAO:

132773697(SPDEF)

PVT:	110081360(SPDEF)

SUND:

121929237(SPDEF)

PBI:	103051339(SPDEF)

PMUR:

107292027(SPDEF)

CTIG:

120306214(SPDEF)

TSR:	106537576(SPDEF)

PGUT:

117663968(SPDEF)

APRI:

131196138(SPDEF)

PTEX:

113449043(SPDEF)

NSS:	113420447(SPDEF)

VKO:	123034087(SPDEF)

PMUA:

114599239(SPDEF)

PRAF:

128416028(SPDEF)

ZVI:	118089355(SPDEF)

HCG:	128322555(SPDEF)

GJA:	107121100(SPDEF)

STOW:

125432463(SPDEF)

EMC:	129329704(SPDEF)

XLA:	108709449(spdef.S)

XTR:	779866(spdef)

NPR:	108790367(SPDEF)

RTEM:

120927234(SPDEF)

BBUF:

120995153(SPDEF)

BGAR:

122932605(SPDEF)

PWL:	138300017(SPDEF)

MUO:	115481624(SPDEF)

GSH:	117347903(SPDEF)

DRE:	100003543(spdef)

SRX:	107724522 107744410

SANH:

107666045 107696418

SGH:	107587644 107595455

CCAR:

109072319 109074015

CAUA:

113051156 113094799 113104177

CGIB:

PTET:

LROH:

OMC:

PPRM:

RKG:

MAMB:

CIDE:

CERY:

MASI:

TROS:

TDW:

MANU:

PDAB:

IPU:	108271967 108276361

IFU:	128614924 128619545

PHYP:

113525331 113530144(spdef)

SMEO:

124397232 124398995

TFD:	113642674 113650923

TVC:	132844651 132862240

CGAR:

128510587 128526835

NGRA:

132884394 132896341

TRN:	134316329 134333888

AMEX:

103035055 103037006

CMAO:

118808543 118822700

EEE:	113571673(spdef) 113572350

CHAR:

105894205 105897827

SPIL:

134087966 134092641

TRU:	101061478 101071401

TFS:	130524930 130530491

TNG:	GSTEN00033917G001

LCO:	104928313 104932797

NCC:	104942558(spdef) 104965631

TBEN:

CGOB:

PGEO:

GACU:

EMAC:

ELY:	117256657 117257948

EFO:	125887063 125891362

PLEP:

121947592 121953606

SLUC:

116051481 116062080

ECRA:

117943294 117947990

ESP:	116687831 116692272(spdef)

PFLV:

114554851 114558506

GAT:	120828713 120835702

PPUG:

119221702 119229723

AFB:	129099501 129106391

CLUM:

PSWI:

CANA:

CVE:

MSAM:

SCHU:

CUD:	121507193 121517868

SPUL:

LMIX:

ALAT:

ASTR:

MZE:	101479796(spdef)

ONL:	100700763(spdef)

OAU:

116320298

OLA:	101167865(spdef)

OML:

112145356

CSAI:

133448398

XMA:	102227780(spdef)

XCO:	114134892(spdef)

XHE:	116711254(spdef)

PRET:

103464725(spdef)

PFOR:

103134620(spdef)

PLAI:

106952248(spdef)

PMEI:

106918240(spdef)

GAF:

122833469

PPRL:

129372751

CVG:	107089144(spdef)

CTUL:

119779012

GMU:

124857133

NFU:	107385019(spdef)

KMR:

108231572

ALIM:

106518308(spdef)

NWH:

119412335

AOCE:

111569784 111572140

EJA:	138193044 138197920

BFRE:

138616676 138624326

MCEP:

125006207 125008303

CSEM:

103385311(spdef) 103386600

POV:	109635292 109635430

SSEN:

122767564 122776948

SSOE:

131461500 131468533

HHIP:

117761728 117765423

HSP:	118102034 118110605

PPLT:

128442914 128455513

SMAU:

118310114 118317028

LCF:	108882106 108888092

SDU:	111233611 111238207

SLAL:

111655018(spdef) 111657928

XGL:	120783072 120804208

HCQ:	109506981 109528251

SSCV:

125977783 125989171

SBIA:

133495512 133507643

PEE:	133409071 133414099

PTAO:

133475341 133483697

BPEC:

110164492 110168685 110174823

ENY:	140366196(spdef)

MALB:

109959103 109966065(spdef)

BSPL:

114855327 114858668

SJO:	128356265 128357765

SSCO:

133978061 133987680

GMH:	115547571(spdef) 115557590

SASA:

106566011 106566918 106572345(spdef) 106582703

STRU:

115151032 115165809 115168141 115207392

OTW:	112216125 112221626 112221965 112254181

OMY:	110492186 110494728 110527730 110532424

OGO:	124003637 124031617 124032055 124045870

ONE:	115102311 115132290 115135636 115143518

OKI:	109866328 109869129 109890142 109907020

OKE:	118359832 118360893 118389612 118399942

OMM:	135504274 135528210 135540343 135542295

OCLA:

139368614 139369921 139414214 139417308

SALP:

111966584 111969715 111977080 112080679

SNH:	120024206 120058619 120061569 120065013

CCLU:

121538472 121545614 121557263 121578708

ELS:	105022780(spdef) 105029211

OEP:	134018944 134029467

SFM:	108939177(spdef)

PKI:	111837119(spdef) 111855048

AANG:

118208024 118210938

AROT:

135234351 135238403

CCOG:

133109386 133139183

LOC:	102698269(spdef)

PSPA:

121300082 121300115

ARUT:

117397924 117426907

PSEX:

120525952

LCM:	102355887(SPDEF)

CMK:	103179064 103181884

RTP:

CPLA:

HOC:

LERI:

LRJ:

BFO:

BBEL:

CIN:

SPU:	373307(Ets4)

LPIC:

APLC:

ARUN:

AAMU:

AFIL:

AJC:

SKO:

PFLL:

DME:	Dmel_CG5583(Ets98B)

DER:

6554384

DSE:

6618710

DSI:	Dsimw501_GD21351(Dsim_GD21351)

DYA:	Dyak_GE23760

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI22028

DAZ:

108609089

DNV:

108648986

DHE:

111593237

DVI:	6633185(Ets98B)

CCAT:

BOD:

BDR:

RZE:

AOQ:

ALUD:

TDA:	119676331 119680203

MDE:	101888454 105262092

SCAC:

106084478

LCQ:

111675765

LSQ:

119600900

CVJ:	135957398(Ets98B)

GFS:

ECOE:

CLON:

HIS:

ACOZ:

AARA:

ASTE:

AFUN:

AMOU:

AAG:

AALB:

ASUA:

CQU:	CpipJ_CPIJ006783

CPII:

CBRI:

CNS:

BCOO:

LLL:

PPAP:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BHUN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

COBS:

139108436(Ets98b)

TLN:	139822918(Ets98b)

HST:

DQU:

CFO:

FEX:

PMEC:

138932807(Ets98b)

LHU:	105670831(Ets98B)

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

AROA:

TCA:

TMOL:

138133853(Ets98B)

DPA:

109533579

ESIM:

136408530(Ets98B)

EFOR:

136342881(Ets98B)

SOY:

ATD:

CSET:

HAXR:

AGB:

LDC:

DVV:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

BPHI:

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

ONU:

ATRA:

GMW:

PXY:

PGW:

LGLY:

CSTB:

CFEL:

CCRN:

API:

DNX:

RMD:

BTAB:

CLEC:

HHAL:

106677162(Ets98B)

NLU:

111054631

HVI:

124362700

MQU:	128990832 128990852

PHU:	Phum_PHUM503640

FOC:

TPAL:

ZNE:

CSEC:

PAME:

138695007(Ets98B)

SGRE:

IEL:

HAMR:

FCD:

DMK:

DPZ:

AFRA:

PVM:

PJA:

PCHN:

PMOO:

HAME:

PTRU:

MNZ:

MRJ:

LSM:

PPOI:

DSV:

RSAN:

RMP:

VDE:

VJA:

TUT:

DPTE:

DFR:

CSCU:

CVS:

PTEP:

ABRU:

UDV:

SDM:

LPOL:

CEL:	CELE_F22A3.1(ets-4)

CBR:	CBG_10834(Cbr-ets-4)

CRQ:	GCK72_024603

BMY:	BM_BM3502(Bma-ets-4)

LOA:	LOAG_13336

PVUL:

PCAN:

LSAX:

BGT:

GAE:

HRF:

HRJ:

HASI:

HCRA:

CRG:	105339784 105339786

CANU:

128175953 128188546

CVN:	111104106 111110225

OED:	125646317 125647577

MYI:

PMAX:

AIRR:

RPHI:

MAEA:

OBI:

OSN:	115214443 115230719

LJP:

LAK:

LLON:

NVE:

EPA:

ATEN:

ADF:	107334326 107349515 107349517

AMIL:

PDAM:

SPIS:

Reference

PMID:10625666

Authors

Oettgen P, Finger E, Sun Z, Akbarali Y, Thamrongsak U, Boltax J, Grall F, Dube A, Weiss A, Brown L, Quinn G, Kas K, Endress G, Kunsch C, Libermann TA

Title

PDEF, a novel prostate epithelium-specific ets transcription factor, interacts with the androgen receptor and activates prostate-specific antigen gene expression.

Journal

J Biol Chem 275:1216-25 (2000)
DOI:10.1074/jbc.275.2.1216

Sequence

[hsa:25803]

LinkDB

DBGET integrated database retrieval system