NETWORK: N01286
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Entry
N01286 Network
Name
Escherichia EspG to Microtubule-RHOA signaling pathway
Definition
(EspG,
EspG2) -| (TUBA+TUBB)
Expanded
(K12785,
K12809) -| ((7846,
10376,
84790,
7278,
113457,
112714,
7277,
51807)+(203068,
81027,
7280,
347733,
10381,
10382,
10383,
84617,
347688))
Class
nt06135
Cytoskeletal regulation (viruses and bacteria)
Type
Pathogen
Pathway
hsa05130
Pathogenic Escherichia coli infection
Disease
H00277
Enterohemorrhagic Escherichia coli (EHEC) infection
H00278
Enteropathogenic Escherichia coli (EPEC) infection
Gene
7846
TUBA1A; tubulin alpha 1a
10376
TUBA1B; tubulin alpha 1b
84790
TUBA1C; tubulin alpha 1c
7278
TUBA3C; tubulin alpha 3c
113457
TUBA3D; tubulin alpha 3d
112714
TUBA3E; tubulin alpha 3e
7277
TUBA4A; tubulin alpha 4a
51807
TUBA8; tubulin alpha 8
203068
TUBB; tubulin beta class I
81027
TUBB1; tubulin beta 1 class VI
7280
TUBB2A; tubulin beta 2A class IIa
347733
TUBB2B; tubulin beta 2B class IIb
10381
TUBB3; tubulin beta 3 class III
10382
TUBB4A; tubulin beta 4A class IVa
10383
TUBB4B; tubulin beta 4B class IVb
84617
TUBB6; tubulin beta 6 class V
347688
TUBB8; tubulin beta 8 class VIII
Perturbant
K12785
(EspG)
espG; LEE-encoded effector EspG
K12809
(EspG2)
espG2; T3SS secreted effector EspG-like protein
Reference
PMID:
15318166
Authors
Matsuzawa T, Kuwae A, Yoshida S, Sasakawa C, Abe A.
Title
Enteropathogenic Escherichia coli activates the RhoA signaling pathway via the stimulation of GEF-H1.
Journal
EMBO J 23:3570-82 (2004)
DOI:
10.1038/sj.emboj.7600359
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