KEGG ORTHOLOGY: K13157

ORTHOLOGY: K13157

Entry

K13157                      KO

Symbol

RNPC3

Name

U11/U12 small nuclear ribonucleoprotein 65 kDa protein

Disease

H00254

Growth hormone deficiency

H02035

Isolated growth hormone deficiency

H02036

Combined pituitary hormone deficiency

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03041 Spliceosome
    K13157  RNPC3; U11/U12 small nuclear ribonucleoprotein 65 kDa protein
Spliceosome [BR:ko03041]
Other splicing related proteins
  Minor spliceosome components
   Minor spliceosome specific factors
    K13157  RNPC3; U11/U12 small nuclear ribonucleoprotein 65 kDa protein

Genes

HSA:	55599(RNPC3)

PTR:	469395(RNPC3)

PPS:	100983423(RNPC3)

GGO:	101142306(RNPC3)

PON:	100173567(RNPC3)

NLE:	100594806(RNPC3)

HMH:	116469694(RNPC3)

MCC:	717115(RNPC3)

MCF:	101865171(RNPC3)

MTHB:

126947711

MNI:	105466268(RNPC3)

CSAB:

103224344(RNPC3)

CATY:

105590120(RNPC3)

PANU:

101018016(RNPC3)

TGE:	112607915(RNPC3)

MLEU:

105536547(RNPC3)

RRO:	104669570(RNPC3)

RBB:	108522103(RNPC3)

TFN:	117076361(RNPC3)

PTEH:

111525476(RNPC3)

CANG:

105506914(RNPC3)

CJC:	100393438(RNPC3)

SBQ:	101039823(RNPC3)

CIMI:

108292223(RNPC3)

CSYR:

103271217(RNPC3)

MMUR:

105864004(RNPC3)

LCAT:

123634961(RNPC3)

PCOQ:

105818741(RNPC3)

OGA:	100955715(RNPC3)

MMU:	67225(Rnpc3)

MCAL:

110290915(Rnpc3)

MPAH:

110320986(Rnpc3)

RNO:	691538(Rnpc3)

MCOC:

116093661(Rnpc3)

ANU:	117706694(Rnpc3)

MUN:	110566002(Rnpc3)

CGE:	100773770(Rnpc3)

MAUA:

101833895(Rnpc3)

PROB:

127223120(Rnpc3)

PLEU:

114711012(Rnpc3)

MORG:

121451639(Rnpc3)

MFOT:

126513732

AAMP:

119801272(Rnpc3)

NGI:	103751578(Rnpc3)

HGL:	106007533(Rnpc3)

CPOC:

100723783(Rnpc3)

CCAN:

109698188(Rnpc3)

DORD:

105997108(Rnpc3)

DSP:	122108423(Rnpc3)

PLOP:

125364284(Rnpc3)

NCAR:

124983620

MMMA:

107156561(Rnpc3)

OCU:

100343986

OPI:	101532847(RNPC3)

TUP:	102492402(RNPC3)

GVR:	103593881(RNPC3)

CFA:	490136(RNPC3)

CLUD:

112640761(RNPC3)

VVP:	112918225(RNPC3)

VLG:	121486931(RNPC3)

NPO:	129519462(RNPC3)

AML:	100465295(RNPC3)

UMR:	103669313(RNPC3)

UAH:	113254332(RNPC3)

UAR:	123795143(RNPC3)

ELK:

111142813

LLV:

125097518

MPUF:

101691970(RNPC3)

MNP:	132001215(RNPC3)

MLK:	131810403(RNPC3)

NVS:	122900258(RNPC3)

ORO:	101366931(RNPC3)

EJU:	114208051(RNPC3)

ZCA:	113929682(RNPC3)

MLX:	118019071(RNPC3)

NSU:	110580366(RNPC3)

LWW:	102739142(RNPC3)

FCA:	101092872(RNPC3)

PYU:	121027581(RNPC3)

PCOO:

112868867(RNPC3)

PBG:	122480854(RNPC3)

PVIV:

125172045(RNPC3)

LRUF:

124514767

PTG:	102953838(RNPC3)

PPAD:

109271947(RNPC3)

PUC:

125912331

AJU:

106967051

HHV:	120219795(RNPC3)

BTA:	768060(RNPC3)

BOM:	102275716(RNPC3)

BIU:	109556001(RNPC3)

BBUB:

102406872(RNPC3)

BBIS:

104981712(RNPC3)

CHX:	102169929(RNPC3)

OAS:	101118319(RNPC3)

BTAX:

128044390(RNPC3)

ODA:	120856775(RNPC3)

CCAD:

122436615(RNPC3)

MBEZ:

129541725(RNPC3)

SSC:	100522864(RNPC3)

CFR:	102523043(RNPC3)

CBAI:

105065367(RNPC3)

CDK:	105085613(RNPC3)

VPC:	102539032(RNPC3)

BACU:

102997460(RNPC3)

BMUS:

118880608(RNPC3)

LVE:	103090953(RNPC3)

OOR:	101288093(RNPC3)

DLE:	111180103(RNPC3)

PCAD:

102983609(RNPC3)

PSIU:

116751142(RNPC3)

NASI:

112403633(RNPC3)

ECB:	100054806(RNPC3)

EPZ:	103555034(RNPC3)

EAI:	106846452(RNPC3)

MYB:	102254630(RNPC3)

MYD:	102757136(RNPC3)

MMYO:

118672853(RNPC3)

MLF:	102438755(RNPC3)

PKL:	118727172(RNPC3)

EFUS:

103291130(RNPC3)

MNA:	107537175(RNPC3)

DRO:	112313522(RNPC3)

SHON:

118990622(RNPC3)

AJM:	119054961(RNPC3)

PDIC:

114488973(RNPC3)

PHAS:

123804613(RNPC3)

MMF:	118637102(RNPC3)

PPAM:

129063889(RNPC3)

HAI:	109376412(RNPC3)

RFQ:	117014617(RNPC3)

PALE:

102885452(RNPC3)

PGIG:

120607855(RNPC3)

PVP:	105297482(RNPC3)

RAY:	107504397(RNPC3)

MJV:	108405475(RNPC3)

TOD:	119235261(RNPC3)

SARA:

101547797(RNPC3)

SETR:

125997289(RNPC3)

LAV:	100661338(RNPC3)

TMU:

101347203

ETF:	101641692(RNPC3)

DNM:

101427473

MDO:	100032985(RNPC3)

GAS:	123243975(RNPC3)

SHR:	100917961(RNPC3)

AFZ:

127559438

PCW:	110217682(RNPC3)

OAA:	100078718(RNPC3)

GGA:	424458(RNPC3)

PCOC:

116243520(RNPC3)

MGP:	100548553(RNPC3)

CJO:	107317337(RNPC3)

TPAI:

128072128(RNPC3)

LMUT:

125693459(RNPC3)

NMEL:

110402459(RNPC3)

APLA:

101799573(RNPC3)

ACYG:

106039387(RNPC3)

CATA:

118243422(RNPC3)

AFUL:

116492191(RNPC3)

TGU:	100222624(RNPC3)

LSR:	110484221(RNPC3)

SCAN:

103815126(RNPC3)

PMOA:

120510427(RNPC3)

OTC:	121344578(RNPC3)

PRUF:

121360462(RNPC3)

GFR:	102043128(RNPC3)

FAB:	101822194(RNPC3)

OMA:	130256309(RNPC3)

PHI:	102112348(RNPC3)

PMAJ:

107208200(RNPC3)

CCAE:

111932596(RNPC3)

CCW:	104695388(RNPC3)

CBRC:

103612760(RNPC3)

ETL:	114061675(RNPC3)

ZAB:	102061490(RNPC3)

ACHL:

103809473(RNPC3)

SVG:	106858523(RNPC3)

MMEA:

130572548(RNPC3)

HRT:	120756657(RNPC3)

FPG:	101912861(RNPC3)

FCH:	102056473(RNPC3)

CLV:	102093835(RNPC3)

EGZ:	104134039(RNPC3)

NNI:	104017970(RNPC3)

PCRI:

104029183(RNPC3)

PLET:

104621743(RNPC3)

EHS:	104514611(RNPC3)

PCAO:

104040047(RNPC3)

ACUN:

113482874(RNPC3)

TALA:

104355913(RNPC3)

PADL:

103925172(RNPC3)

AFOR:

103902206(RNPC3)

ACHC:

115348709(RNPC3)

HALD:

104310804(RNPC3)

HLE:	104829418(RNPC3)

AGEN:

126041558

GCL:

127019086

CCRI:

104158938(RNPC3)

CSTI:

104550501(RNPC3)

CMAC:

104481941(RNPC3)

MUI:	104534207(RNPC3)

BREG:

104629912(RNPC3)

FGA:	104070156(RNPC3)

GSTE:

104251179(RNPC3)

LDI:	104347997(RNPC3)

MNB:	103782283(RNPC3)

OHA:	104329710(RNPC3)

NNT:	104409542(RNPC3)

SHAB:

115611357(RNPC3)

DPUB:

104309720(RNPC3)

PGUU:

104458570(RNPC3)

ACAR:

104517852(RNPC3)

CPEA:

104396883(RNPC3)

AVIT:

104268040(RNPC3)

CVF:	104286340(RNPC3)

RTD:	128914053(RNPC3)

CUCA:

104062450(RNPC3)

TEO:	104369676(RNPC3)

AAM:	106499740(RNPC3)

AROW:

112966843(RNPC3)

NPD:	112951243(RNPC3)

TGT:	104569211(RNPC3)

DNE:	112989848(RNPC3)

SCAM:

104140510(RNPC3)

ASN:	102376141(RNPC3)

AMJ:	102573584(RNPC3)

PSS:	102449515(RNPC3)

CMY:	102933861(RNPC3)

CCAY:

125641009(RNPC3)

DCC:	119860296(RNPC3)

CPIC:

101953862(RNPC3)

TST:	117882300(RNPC3)

CABI:

116831691(RNPC3)

MRV:	120370837(RNPC3)

ACS:	100556831(rnpc3)

ASAO:

132774190(RNPC3)

PVT:

110091523

SUND:

121929599(RNPC3)

PBI:	103058833(RNPC3)

PMUR:

107292304(RNPC3)

CTIG:

120320108(RNPC3)

TSR:	106555342(RNPC3)

PGUT:

117677280(RNPC3)

APRI:

131193994(RNPC3)

PTEX:

113436160(RNPC3)

NSS:	113414758(RNPC3)

VKO:	123024593(RNPC3)

PMUA:

114598693(RNPC3) 114598694

PRAF:

128415416(RNPC3)

ZVI:	118089071(RNPC3)

HCG:	128323269(RNPC3)

GJA:	107114563(RNPC3)

STOW:

125432723(RNPC3)

EMC:	129331134(RNPC3)

XLA:	108714429(rnpc3.L)

XTR:	548771(rnpc3)

NPR:	108788517(RNPC3)

RTEM:

120945610(RNPC3)

BBUF:

120979069(RNPC3)

BGAR:

122943619(RNPC3)

MUO:	115471666(RNPC3)

GSH:	117346625(RNPC3)

DRE:	565672(rnpc3)

SRX:

107729643

SANH:

107677212 107698067

SGH:	107548897 107590356

CCAR:

109092222

CAUA:

113042511(rnpc3)

CGIB:

128013486

PTET:

122329499(rnpc3)

LROH:

127155411(rnpc3)

OMC:	131533712(rnpc3)

PPRM:

120485486(rnpc3)

RKG:	130084041(rnpc3)

MAMB:

125258128(rnpc3)

CIDE:

127506242

MASI:

127434468

TROS:

130547063(rnpc3)

TDW:	130412823(rnpc3)

MANU:

129426461(rnpc3)

IPU:

108266399

IFU:	128606153(rnpc3)

PHYP:

113547546(rnpc3)

SMEO:

124384333(rnpc3)

TFD:	113651842(rnpc3)

TVC:	132845506(rnpc3)

AMEX:

103039358(rnpc3)

CMAO:

118815396(rnpc3)

EEE:	113584544(rnpc3)

CHAR:

105889386(rnpc3)

TRU:	101080053(rnpc3)

TFS:	130513453(rnpc3)

TNG:	GSTEN00035103G001

LCO:	104923105(rnpc3)

NCC:	104954181(rnpc3)

TBEN:

117484163(rnpc3)

CGOB:

115025834(rnpc3)

PGEO:

117465476(rnpc3)

GACU:

117543676(rnpc3)

EMAC:

134883787(rnpc3)

ELY:

117264286

EFO:	125882090(rnpc3)

PLEP:

121960938(rnpc3)

SLUC:

116046325(rnpc3)

ECRA:

117937696(rnpc3)

ESP:	116672343(rnpc3)

PFLV:

114549647(rnpc3)

GAT:	120811666(rnpc3)

PPUG:

119198893(rnpc3)

AFB:	129110657(rnpc3)

CLUM:

117749339(rnpc3) 117750340

PSWI:

130206008(rnpc3)

MSAM:

119907233(rnpc3)

SCHU:

122866923(rnpc3)

CUD:	121527326(rnpc3)

ALAT:

119008551(rnpc3)

MZE:	101482291(rnpc3)

ONL:	100710010(rnpc3)

OAU:	116335796(rnpc3)

OLA:	101168252(rnpc3)

OML:	112151550(rnpc3)

CSAI:

133423034(rnpc3)

XMA:	102234017(rnpc3)

XCO:	114137150(rnpc3)

XHE:	116711959(rnpc3)

PRET:

103482287(rnpc3)

PFOR:

103148005(rnpc3)

PLAI:

106962487(rnpc3)

PMEI:

106929025(rnpc3)

GAF:	122824232(rnpc3)

PPRL:

129364959(rnpc3)

CVG:	107084910(rnpc3)

CTUL:

119795969(rnpc3)

GMU:	124858452(rnpc3)

NFU:	107382666(rnpc3) 107386000

KMR:	108245409(rnpc3)

ALIM:

106526411(rnpc3)

NWH:	119426879(rnpc3)

AOCE:

111574565(rnpc3)

MCEP:

124995948(rnpc3)

CSEM:

103377081(rnpc3)

POV:	109629522(rnpc3)

SSEN:

122781694(rnpc3)

HHIP:

117754108(rnpc3)

HSP:	118098826(rnpc3)

SMAU:

118291378(rnpc3)

LCF:

108898315

SDU:	111228253(rnpc3)

SLAL:

111648152(rnpc3)

XGL:	120790185(rnpc3)

HCQ:	109514244(rnpc3)

SSCV:

125986230

SBIA:

133492970(rnpc3)

PEE:	133396744(rnpc3)

PTAO:

133470361(rnpc3)

BPEC:

110165635(rnpc3)

MALB:

109975031(rnpc3)

BSPL:

114854210(rnpc3)

SJO:	128382433(rnpc3)

SASA:

106578481(rnpc3)

STRU:

115153032(rnpc3)

OTW:	112215527(rnpc3)

OMY:	110535478(rnpc3)

OGO:	123991197(rnpc3)

ONE:	115105045(rnpc3)

OKI:	109909965(rnpc3)

OKE:	118361632(rnpc3)

SALP:

111973008(rnpc3)

SNH:	120027842(rnpc3)

CCLU:

121550095(rnpc3)

ELS:	105022601(rnpc3)

SFM:	108927655(rnpc3)

PKI:	111840648(rnpc3)

AANG:

118226556(rnpc3)

LOC:	102686275(rnpc3)

PSPA:

121330718(rnpc3)

ARUT:

117403505(rnpc3)

PSEX:

120514898(rnpc3)

LCM:	102365524(RNPC3)

CMK:	103174749(rnpc3)

RTP:	109919130(rnpc3)

CPLA:

122554090(rnpc3)

HOC:	132819212(rnpc3)

LERI:

129716178(rnpc3)

PMRN:

116944804(RNPC3)

LRJ:	133341687(RNPC3)

BFO:

BBEL:

CIN:

SCLV:

SPU:

APLC:

SKO:

DME:	Dmel_CG44249(CG44249)

DER:

DSR:

TDA:

SCAC:

ECOE:

CLON:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AFUN:

AMOU:

AALB:

CQU:	CpipJ_CPIJ003638

CPII:

BCOO:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

VCAN:

CCIN:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

TCA:

DPA:

SOY:

AGRG:

ATD:

CSET:

AGB:

LDC:

NVL:

APLN:

PPYR:

OTU:

BMOR:

MSEX:

DPL:	KGM_210364

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

PRAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

PXY:

PGW:

CFEL:

CCRN:

API:

DNX:

AGS:

RMD:

ACOO:

DVT:

BTAB:

DCI:

CLEC:

HHAL:

NLU:

HVI:

PHU:	Phum_PHUM293630

FOC:

TPAL:

ZNE:

CSEC:

SGRE:

BROR:

IEL:

DPX:	DAPPUDRAFT_313833

DMK:

DPZ:

PVM:

PJA:

PCHN:

PMOO:

HAME:

PCLA:

CQD:

PTRU:

ESN:

MNZ:

HAZT:

PPOI:

DSV:

RSAN:

RMP:

VDE:

VJA:

TUT:

DPTE:

DFR:

CSCU:

PTEP:

ABRU:

UDV:

SDM:

LPOL:

PMEO:

TSP:

HRO:	HELRODRAFT_65555

PVUL:

126825678

PCAN:

112567654

BGT:	106069994 106075602

GAE:

HRF:

HRJ:

CRG:

CVN:

CANU:

MYI:

PMAX:

MCAF:

RPHI:

DPOL:

OBI:

OSN:

LAK:

SMM:	Smp_023270.1

SHX:	MS3_00006509(RNPC3_1)

OVI:	T265_10171

EGL:

NVE:

EPA:

ATEN:

ADF:

AMIL:

PDAM:

SPIS:

DGT:

XEN:

HMG:

HSY:

TAD:	TRIADDRAFT_58601

AQU:

ATH:

ALY:

CRB:

CSAT:

104739514 104755111 104767531

EUS:	EUTSA_v10007645mg

BRP:

103871650

BNA:	106351182 106412290

BOE:

RSZ:

THJ:

CPAP:

CIT:

CIC:	CICLE_v10020067mg

PVY:	116105856 116120716

MINC:

123220923

TCC:

18599954

GRA:

105804534

GHI:	107892375 107961890

GAB:

108470622

HSYR:

120133546 120185346

DZI:	111277084 111295083

EGR:

104442648

GMX:	100814307 100818499

GSJ:	114389195 114400677

PVU:	PHAVU_001G100700g

VRA:

VAR:

VUN:

VUM:

CCAJ:

APRC:

MTR:

TPRA:

CAM:

PSAT:

127126665 127126668 127126671

VVO:

131609895

LJA:	Lj1g3v3948260.1(Lj1g3v3948260.1)

ADU:

107468328

AIP:	107611315 107634015

AHF:	112709951 112721759 112722540

LANG:

109357611

PCIN:

129307317

QSA:	O6P43_009802

FVE:

RCN:

PPER:

PMUM:

PAVI:

PDUL:

MDM:

MSYL:

PXB:

ZJU:

MNT:

CSAV:

CSV:

CMO:

BHJ:

MCHA:

CMAX:

CMOS:

CPEP:

RCU:

JCU:

HBR:

MESC:

POP:	7469865 7489651

PEU:

PALZ:

JRE:

CILL:

CAVE:

QSU:

QLO:

TWL:

VVI:	100243611 100247346

VRI:	117913805 117914933

SLY:

SPEN:

SOT:

SSTN:

SDUL:

CANN:

LBB:

NTA:	107777363 107777783 107819191

NSY:

NTO:

NAU:

INI:

ITR:

SIND:

OEU:

EGT:

SSPL:

SMIL:

SHIS:

APAN:

HAN:

ECAD:

LSV:

CCAV:

DCR:

CSIN:

RVL:

AEW:	130757801 130758828

BVG:

104884555

SOE:

110776264

CQI:	110690009 110728808

ATRI:

130823874

MOF:

131157264

NNU:	104590833 104597725

MING:

TSS:

PSOM:

OSA:

DOSA:

Os03t0326600-01(Os03g0326600)

OBR:

102715553

OGL:

127765121

BDI:

100832030

ATS:	109746883 109760500

TDC:	119270699 119314996 119320887 119334567

TAES:

123047475 123122649 123132065 123181258

TUA:	125508052 125529689

LPER:

LRD:

SBI:

ZMA:

SITA:

SVS:

PVIR:

PHAI:

PDA:

EGU:

MUS:

ZOF:	121969339 121974460

DCT:

110113493

PEQ:	110017986 110028943

AOF:

MSIN:

NCOL:

ATR:

SMO:	SELMODRAFT_235257

PPP:

112282157

DFA:

DFA_00806

» show all

Reference

PMID:16096647

Authors

Benecke H, Luhrmann R, Will CL

Title

The U11/U12 snRNP 65K protein acts as a molecular bridge, binding the U12 snRNA and U11-59K protein.

Journal

EMBO J 24:3057-69 (2005)
DOI:10.1038/sj.emboj.7600765

Sequence

[hsa:55599]

Reference

PMID:18559850

Authors

Pessa HK, Will CL, Meng X, Schneider C, Watkins NJ, Perala N, Nymark M, Turunen JJ, Luhrmann R, Frilander MJ

Title

Minor spliceosome components are predominantly localized in the nucleus.

Journal

Proc Natl Acad Sci U S A 105:8655-60 (2008)
DOI:10.1073/pnas.0803646105

Sequence

[hsa:55599]

LinkDB

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