ORTHOLOGY: K16420
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Entry
K16420 KO
Symbol
rapA_B_C
Name
rapamycin polyketide synthase A/B/C
Pathway
map01052
Type I polyketide structures
Brite
KEGG Orthology (KO) [BR:
ko00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
01052 Type I polyketide structures
K16420 rapA_B_C; rapamycin polyketide synthase A/B/C
09180 Brite Hierarchies
09181 Protein families: metabolism
01008 Polyketide biosynthesis proteins
K16420 rapA_B_C; rapamycin polyketide synthase A/B/C
Polyketide biosynthesis proteins [BR:
ko01008
]
Polyketide synthase (PKS)
Modular type I PKS
cis-AT PKS
Rapamycin PKS
K16420 rapA_B_C; rapamycin polyketide synthase A/B/C
BRITE hierarchy
Genes
SRC:
M271_40735
SMAL:
SMALA_8316
SMALA_8318
SSOI:
I1A49_45320
I1A49_45330
AREV:
RVR_8802
ACTN:
L083_2961
(rapC)
L083_2963
(rapA)
L083_2964
(rapB)
AG:
CAA60459
(rapB)
CAA60460
(rapA)
CAA60462
(rapC)
Taxonomy
UniProt
Reference
PMID:
7644502
Authors
Schwecke T, Aparicio JF, Molnar I, Konig A, Khaw LE, Haydock SF, Oliynyk M, Caffrey P, Cortes J, Lester JB, et al.
Title
The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin.
Journal
Proc Natl Acad Sci U S A 92:7839-43 (1995)
DOI:
10.1073/pnas.92.17.7839
Sequence
[ag:
CAA60460
CAA60459
CAA60462
]
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