KEGG   ORTHOLOGY: K18345
Entry
K18345                      KO                                     
Symbol
vanSB, vanS, vanSD
Name
two-component system, OmpR family, sensor histidine kinase VanS [EC:2.7.13.3]
Pathway
map01502  Vancomycin resistance
map02020  Two-component system
Module
M00651  Vancomycin resistance, D-Ala-D-Lac type
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   02020 Two-component system
    K18345  vanSB, vanS, vanSD; two-component system, OmpR family, sensor histidine kinase VanS
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    K18345  vanSB, vanS, vanSD; two-component system, OmpR family, sensor histidine kinase VanS
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K18345  vanSB, vanS, vanSD; two-component system, OmpR family, sensor histidine kinase VanS
  09183 Protein families: signaling and cellular processes
   02022 Two-component system
    K18345  vanSB, vanS, vanSD; two-component system, OmpR family, sensor histidine kinase VanS
   01504 Antimicrobial resistance genes
    K18345  vanSB, vanS, vanSD; two-component system, OmpR family, sensor histidine kinase VanS
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.13  Protein-histidine kinases
    2.7.13.3  histidine kinase
     K18345  vanSB, vanS, vanSD; two-component system, OmpR family, sensor histidine kinase VanS
Protein kinases [BR:ko01001]
 Histidine kinases
  OmpR family
   K18345  vanSB, vanS, vanSD; two-component system, OmpR family, sensor histidine kinase VanS
Two-component system [BR:ko02022]
 OmpR family
  VanS-VanR (VanB type vancomycin resistance)
   K18345  vanSB, vanS, vanSD; two-component system, OmpR family, sensor histidine kinase VanS
Antimicrobial resistance genes [BR:ko01504]
 Gene sets
  Vancomycin resistance modules
   Vancomycin resistance, D-Ala-D-Lac type
    K18345  vanSB, vanS, vanSD; two-component system, OmpR family, sensor histidine kinase VanS
Other DBs
COG: COG0642
GO: 0000155
Genes
AELL: AELL_0215(phoR)
OCK: EXM22_09320
BCA: BCE_2750
BCR: BCAH187_C0256
BCU: BCAH820_3208
BCG: BCG9842_B2562
BNC: BCN_P242
BCEF: BcrFT9_02139 BcrFT9_02453
BCY: Bcer98_0801
BTT: HD73_3279
BTHR: YBT1520_16160
BTHI: BTK_16195
BTC: CT43_CH2707
BTM: MC28_1919 MC28_G290
BTG: BTB_c28350(vanSB1)
BTI: BTG_06075
BTN: BTF1_11130
BTHT: H175_ch2756
BTHU: YBT1518_15025
BTW: BF38_4354
BTHY: AQ980_14790
BWE: BcerKBAB4_2423 BcerKBAB4_5470
BWW: bwei_2411
BMYO: BG05_3401
BTY: Btoyo_0011
BMYC: DJ92_3641
BBY: CY96_12375
BWD: CT694_14540 CT694_30690 CT694_33085
BMOB: MLA2C4_14440
BNT: GSN03_12695 GSN03_27420
BPAM: AABL52_13760
BACI: B1NLA3E_07310
BAEZ: DPQ26_14790 DPQ26_15020
BAAZ: GD442_12745
BABD: EKQ63_14435
BCIR: C2I06_18125
NTX: NQZ71_24925
NIL: L8T27_024555
LSP: Bsph_2139(vanSB)
LYO: NV349_10050
LYR: AB9L17_23950
TAP: GZ22_02820
LAO: AOX59_15305
BMUR: ABE28_009570
PBUT: DTO10_23090
PPSR: I6J18_14735
PERI: RE409_11565
PERJ: JNUCC41_05325
AQT: FN924_15740
PSYH: D0S48_08860
SEDD: ERJ70_02450
LMO: lmo1061
LMN: LM5578_1144
LMY: LM5923_1098
LMT: LMRG_00523
LMOC: LMOSLCC5850_1067
LMOE: BN418_1279
LMOB: BN419_1276
LMOD: LMON_1071
LMOW: AX10_13880
LMOQ: LM6179_01380
LMR: LMR479A_1089
LMOM: IJ09_04985
LMG: LMKG_01861
LMS: LMLG_2326
LMJ: LMOG_00659
LMX: LMOSLCC2372_1075
LMOS: LMOSLCC7179_1042
LMOY: LMOSLCC2479_1074
LWE: lwe1039
LNW: OTR81_08655
EAN: Eab7_2025
EXI: A0126_10715
BBE: BBR47_52010
BFM: BP422_21960
BAGR: BA6348_08520
BPAB: PSE45_21670
BREH: HP435_22160
PJD: Pjdr2_3100 Pjdr2_3221
PPY: PPE_00623
PPM: PPSC2_03520(cseA)
PPO: PPM_0646(cseA)
PPOL: X809_03015
PPQ: PPSQR21_006750
PPOY: RE92_08460
PTA: HPL003_10935
PLV: ERIC2_c37300(resE2)
PBD: PBOR_17860
POD: PODO_08905
PAEN: P40081_18280
PAEF: R50345_09330
PAEQ: R50912_16975
PSTE: PSTEL_14390
PAEA: R70723_24325
PAEE: R70331_16125
PAEJ: H70737_08790
PIH: UB51_21665
PRI: PRIO_4966(vanSB)
PSON: JI735_32505
PPEO: ABE82_03275
PBV: AR543_14270
PXL: BS614_29550
PYG: AWM70_21630
PDH: B9T62_04655
PCX: LPB68_01245
PKB: B4V02_21900
PLUT: EI981_11920 EI981_12425 EI981_18440
PALB: EJC50_06800
PBK: Back11_41330
PPRT: ET464_04670
PBAC: HUB98_13025
PRZ: GZH47_12730
PLYC: GXP70_03805
PTRI: KDC22_16115
PTHI: NDS46_15835 NDS46_26035
PMAH: PTQ21_00990
PAMY: P9222_10650
PDY: QJQ58_05955 QJQ58_26075
PSPN: L1F29_13910
PPAB: KET34_29990
PKP: SK3146_00426(phoR_3)
PHEX: L0M14_28280
PLZH: C0638_04435
PEZZ: HW560_09995
COHN: KCTCHS21_58700
SPSY: AZE41_21400
VIJ: JNUCC6_15865
LFB: C1X05_00280
TVU: AB849_004785
EFA: EF2298(vanSB)
EFC: EFAU004_02779(vanSB)
EFAU: EFAU085_00731(vanSB)
CAE: SMB_G2469
CAY: CEA_G2448
CPE: CPE1926
CPF: CPF_2181
CPR: CPR_1892
CNO: NT01CX_1514
CBO: CBO1967
CBA: CLB_1907
CBH: CLC_1913
CBY: CLM_2185
CBL: CLK_1422
CBK: CLL_A2532 CLL_A3542
CBB: CLD_2657
CBI: CLJ_B2173
CBN: CbC4_0691
CBT: CLH_2299
CBF: CLI_2034
CBM: CBF_2019
CBJ: H04402_01992
CBE: Cbei_1732 Cbei_2399 Cbei_4102
CBZ: Cbs_1732 Cbs_2399 Cbs_4102
CBEI: LF65_01871 LF65_03133
CKL: CKL_2349
CKR: CKR_2069
CLJ: CLJU_c25090
CCB: Clocel_0110
CLS: CXIVA_02800
CLB: Clo1100_2888
CSR: Cspa_c07430(resE4) Cspa_c27980 Cspa_c41820 Cspa_c43680
CPAS: Clopa_3182
CPAT: CLPA_c16260(resE4)
CPAE: CPAST_c16260(resE4)
CSB: CLSA_c27900(resE8) CLSA_c38170(resE14)
CAH: CAETHG_0577
CLT: CM240_0168 CM240_0452
CBV: U729_1835 U729_2933
CSQ: CSCA_0317 CSCA_0334 CSCA_3631
CLD: CLSPO_c19700(vanSB)
CCK: Ccar_09990 Ccar_12895 Ccar_12970 Ccar_23185
CBUT: ATN24_08045 ATN24_17885
CTYK: CTK_C13250
CEU: A7L45_11235
CTAE: BGI42_10010 BGI42_14325
CFM: BJL90_12365
CCHV: BTM20_08675
CARG: RSJ17_02905
CDRK: B9W14_01540 B9W14_16810 B9W14_16880
CIA: BEN51_03585
CSEP: CP523_14385
CDY: F3K33_08565 F3K33_12270
CFER: D4Z93_08240
CGAS: J1C67_10580 J1C67_14055
CLOS: DMR38_12970
CCAA: KQH81_09145
CMAH: C1I91_09900
CRW: CROST_030750(rcsC_8)
CNN: CNEO_1962
CGEL: psyc5s11_39770
CINT: HZF06_15005
CTHD: CDO33_10300
CLOL: ONV75_06825
CLOM: AXY43_00115 AXY43_23285
CCAK: ACFLKC_08660
HHW: NCTC503_02474(phoR_6)
CRS: FQB35_14220
SARJ: HH195_07895
FSA: C5Q98_04880
RPAY: P0092_16620
FPLA: A4U99_11985
RUM: CK1_33670
OHI: H8790_08060
OBJ: EIO64_17620
PFAA: MM59RIKEN_16220 MM59RIKEN_25240
LASA: L9O85_08695
PETR: QKW49_05920
HMB: ACI0CA_09410 ACI0CA_12265
RUK: A4V00_03270 A4V00_03695 A4V00_17410
AMUR: ADH66_05300 ADH66_05735 ADH66_10890
AGAT: RWV98_07470
INT: RX717_04035
DSY: DSY1076
DHD: Dhaf_2158
DOR: Desor_4980
DED: DHBDCA_p2751
DEC: DCF50_p2761
DRU: Desru_1429
DAE: Dtox_2914
FWA: DCMF_05975
TJR: TherJR_2640
ALKA: J0B03_11950
CTHM: CFE_0143
PROM: QO263_08690
BPRS: CK3_04180
BPB: bpr_I1235
BHU: bhn_I1156
RHO: RHOM_11285 RHOM_13290
RIX: RO1_22280
RIM: ROI_10080
CCT: CC1_16960
CCOM: I6K69_13355
ROB: CK5_20900 CK5_23470
BYL: A4V09_04050 A4V09_04080 A4V09_18600
BHAN: CGC63_09100
BLAU: DQQ01_06315
BPRO: PMF13cell1_04633(resE_11) PMF13cell1_04642(baeS_6)
BCOC: BLCOC_49320(sasA_43)
BLAB: EYS05_10905 EYS05_13415
BLIQ: INP51_03995
BWX: NQ550_08740
BLAR: LC508_08255
CPY: Cphy_1288 Cphy_2854
LACY: A4V08_02980 A4V08_06780
CSCI: HDCHBGLK_02180(resE_6) HDCHBGLK_02664(phoR_5) HDCHBGLK_03524(resE_9)
CSH: Closa_3484
CSO: CLS_39260
ARF: AR1Y2_2358
ACAC: EYQ97_06185
HSD: SD1D_0646
LUA: D4A81_06200
EHL: EHLA_1169
ANR: Ana3638_14830 Ana3638_19640
ACEL: acsn021_32350
ACHT: bsdcttw_00170
EEL: EUBELI_01176
RTO: RTO_22290
RGN: RGna_01745 RGna_14655
CBOL: CGC65_11040
DLO: K5I24_13160
ERE: EUBREC_1463
ERT: EUR_09970
ERA: ERE_16230
VGU: HYG85_02745
VPY: HZI73_04930 HZI73_19385
ETM: CE91St48_38890
AHAD: FRZ06_08355
AMT: Amet_1916 Amet_3208
GFE: Gferi_00530 Gferi_24535
PBIF: KXZ80_10410
PSOR: RSJ16_05395 RSJ16_12245
CDF: CD630_21130
PDC: CDIF630_02338
CDC: CD196_1977
CDL: CDR20291_2020
PDF: CD630DERM_21130
ROC: HF520_07225
RIL: CRIB_669
RHOM: FRIFI_0851
PHX: KGNDJEFE_01027(walK_1)
TEM: JW646_17830
TGC: L0P85_10200
TMY: TEMA_08520(rcsC_2)
TPET: TPHSE_23330(rcsC_7)
TVT: TVTCOM_19830(rcsC_5)
PEB: O0R46_04870
EAC: EAL2_c21080(resE)
CAD: Curi_c23320(srrB) Curi_c24990(ssrB)
CAZO: G3A45_11055
MED: MELS_1146
MHW: ACT01_09240
PUF: UFO1_3882
PFT: JBW_00946
MANA: MAMMFC1_02680(phoR_3)
STED: SPTER_10340(rcsC_3)
ERL: AOC36_00700
ETT: AZF37_00045
EGD: GS424_007345
KBS: EPA93_16095
OCY: OSSY52_19590
MINF: MESINF_0439
FVA: FV113G1_05290
FUL: C4N20_03660
FMO: C4N19_01365 C4N19_12595
IPO: Ilyop_0700 Ilyop_1492 Ilyop_2522
 » show all
Reference
PMID:8631706
  Authors
Evers S, Courvalin P
  Title
Regulation of VanB-type vancomycin resistance gene expression by the VanS(B)-VanR (B) two-component regulatory system in Enterococcus faecalis V583.
  Journal
J Bacteriol 178:1302-9 (1996)
DOI:10.1128/JB.178.5.1302-1309.1996
  Sequence
[efa:EF2298]
Reference
PMID:22913355
  Authors
Chancey ST, Zahner D, Stephens DS
  Title
Acquired inducible antimicrobial resistance in Gram-positive bacteria.
  Journal
Future Microbiol 7:959-78 (2012)
DOI:10.2217/fmb.12.63
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