| Entry |
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| Name |
C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
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| Definition |
K00512 K00513 K00497 (K15680,K00071)
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| Diagram |
| M00109 | C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone |
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| Class |
Pathway modules; Lipid metabolism; Sterol biosynthesis
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| Pathway |
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| Orthology |
cytochrome P450, family 21, subfamily A (steroid 21-monooxygenase) [EC: 1.14.14.16] [RN: R03326] K00497 cytochrome P450, family 11, subfamily B1/B2 (steroid 11beta-monooxygenase) [EC: 1.14.15.4] [RN: R02843] |
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| Complete |
| ptr | Pan troglodytes (chimpanzee) |
| pps | Pan paniscus (bonobo) |
| ggo | Gorilla gorilla gorilla (western lowland gorilla) |
| pon | Pongo abelii (Sumatran orangutan) |
| ppyg | Pongo pygmaeus (Bornean orangutan) |
| nle | Nomascus leucogenys (northern white-cheeked gibbon) |
| hmh | Hylobates moloch (silvery gibbon) |
| ssyn | Symphalangus syndactylus (siamang) |
| mcc | Macaca mulatta (rhesus monkey) |
| mcf | Macaca fascicularis (crab-eating macaque) |
| mthb | Macaca thibetana thibetana (Pere David's macaque) |
| mni | Macaca nemestrina (pig-tailed macaque) |
| csab | Chlorocebus sabaeus (green monkey) |
| caty | Cercocebus atys (sooty mangabey) |
| panu | Papio anubis (olive baboon) |
| tge | Theropithecus gelada (gelada) |
| mleu | Mandrillus leucophaeus (drill) |
| rro | Rhinopithecus roxellana (golden snub-nosed monkey) |
| rbb | Rhinopithecus bieti (black snub-nosed monkey) |
| tfn | Trachypithecus francoisi (Francois's langur) |
| pteh | Piliocolobus tephrosceles (Ugandan red Colobus) |
| cang | Colobus angolensis palliatus (Angola colobus) |
| cjc | Callithrix jacchus (white-tufted-ear marmoset) |
| sbq | Saimiri boliviensis boliviensis (Bolivian squirrel monkey) |
| cimi | Cebus imitator (Panamanian white-faced capuchin) |
| anan | Aotus nancymaae (Ma's night monkey) |
| csyr | Carlito syrichta (Philippine tarsier) |
| eruf | Eulemur rufifrons (Bennett's brown lemur) |
| oga | Otolemur garnettii (small-eared galago) |
| mmu | Mus musculus (house mouse) |
| mcal | Mus caroli (Ryukyu mouse) |
| mpah | Mus pahari (shrew mouse) |
| rno | Rattus norvegicus (rat) |
| mcoc | Mastomys coucha (southern multimammate mouse) |
| anu | Arvicanthis niloticus (African grass rat) |
| asyl | Apodemus sylvaticus (European woodmouse) |
| mun | Meriones unguiculatus (Mongolian gerbil) |
| cge | Cricetulus griseus (Chinese hamster) |
| maua | Mesocricetus auratus (golden hamster) |
| prob | Phodopus roborovskii (desert hamster) |
| pleu | Peromyscus leucopus (white-footed mouse) |
| pmav | Peromyscus maniculatus bairdii (prairie deer mouse) |
| morg | Microtus oregoni (creeping vole) |
| mfot | Alexandromys fortis (reed vole) |
| aamp | Arvicola amphibius (Eurasian water vole) |
| cnl | Chionomys nivalis (European snow vole) |
| ngi | Nannospalax galili (Upper Galilee mountains blind mole rat) |
| hgl | Heterocephalus glaber (naked mole-rat) |
| cpoc | Cavia porcellus (domestic guinea pig) |
| ccan | Castor canadensis (American beaver) |
| dord | Dipodomys ordii (Ord's kangaroo rat) |
| dsp | Dipodomys spectabilis (banner-tailed kangaroo rat) |
| plop | Perognathus longimembris pacificus (Pacific pocket mouse) |
| ncar | Sciurus carolinensis (gray squirrel) |
| mmma | Marmota marmota marmota (Alpine marmot) |
| iti | Ictidomys tridecemlineatus (thirteen-lined ground squirrel) |
| ocu | Oryctolagus cuniculus (rabbit) |
| opi | Ochotona princeps (American pika) |
| ocz | Ochotona curzoniae (black-lipped pika) |
| tup | Tupaia belangeri chinensis (Chinese tree shrew) |
| cfa | Canis lupus familiaris (dog) |
| clud | Canis lupus dingo (dingo) |
| vvp | Vulpes vulpes (red fox) |
| vlg | Vulpes lagopus (Arctic fox) |
| npo | Nyctereutes procyonoides (raccoon dog) |
| aml | Ailuropoda melanoleuca (giant panda) |
| umr | Ursus maritimus (polar bear) |
| uah | Ursus arctos (brown bear) |
| uar | Ursus americanus (American black bear) |
| elk | Enhydra lutris kenyoni (northern sea otter) |
| llv | Lutra lutra (Eurasian river otter) |
| mnp | Mustela nigripes (black-footed ferret) |
| mlk | Mustela lutreola (European mink) |
| nvs | Neogale vison (American mink) |
| oro | Odobenus rosmarus divergens (Pacific walrus) |
| eju | Eumetopias jubatus (Steller sea lion) |
| zca | Zalophus californianus (California sea lion) |
| mlx | Mirounga leonina (Southern elephant seal) |
| mano | Mirounga angustirostris (Northern elephant seal) |
| nsu | Neomonachus schauinslandi (Hawaiian monk seal) |
| lww | Leptonychotes weddellii (Weddell seal) |
| fca | Felis catus (domestic cat) |
| pyu | Herpailurus yagouaroundi (jaguarundi) |
| pcoo | Puma concolor (puma) |
| pbg | Prionailurus bengalensis (leopard cat) |
| pviv | Prionailurus viverrinus (fishing cat) |
| lgf | Leopardus geoffroyi (Geoffroy's cat) |
| aju | Acinonyx jubatus (cheetah) |
| ptg | Panthera tigris altaica (Amur tiger) |
| ppad | Panthera pardus (leopard) |
| puc | Panthera uncia (snow leopard) |
| hhv | Hyaena hyaena (striped hyena) |
| ccru | Crocuta crocuta (spotted hyena) |
| biu | Bos indicus (zebu cattle) |
| bjv | Bos javanicus (banteng) |
| bbub | Bubalus bubalis (water buffalo) |
| bke | Bubalus kerabau (carabao) |
| bbis | Bison bison bison (American bison) |
| ocan | Ovis canadensis (bighorn sheep) |
| btax | Budorcas taxicolor (takin) |
| csum | Capricornis sumatraensis (Sumatran serow) |
| oda | Oryx dammah (scimitar-horned oryx) |
| ccad | Cervus canadensis (wapiti) |
| mree | Muntiacus reevesi (Reeves' muntjac) |
| mbez | Moschus berezovskii (Chinese forest musk deer) |
| cfr | Camelus ferus (Wild Bactrian camel) |
| cbai | Camelus bactrianus (Bactrian camel) |
| cdk | Camelus dromedarius (Arabian camel) |
| vpc | Vicugna pacos (alpaca) |
| bacu | Balaenoptera acutorostrata scammoni (minke whale) |
| bmus | Balaenoptera musculus (blue whale) |
| lve | Lipotes vexillifer (Yangtze River dolphin) |
| oor | Orcinus orca (killer whale) |
| lalb | Lagenorhynchus albirostris (white-beaked dolphin) |
| gmf | Globicephala melas (long-finned pilot whale) |
| ddp | Delphinus delphis (saddleback dolphin) |
| dle | Delphinapterus leucas (beluga whale) |
| pcad | Physeter macrocephalus (sperm whale) |
| psiu | Phocoena sinus (vaquita) |
| pphc | Phocoena phocoena (harbor porpoise) |
| nasi | Neophocaena asiaeorientalis asiaeorientalis (Yangtze finless porpoise) |
| ecb | Equus caballus (horse) |
| epz | Equus przewalskii (Przewalski's horse) |
| mmyo | Myotis myotis (greater mouse-eared bat) |
| mdt | Myotis daubentonii (Daubenton's bat) |
| myum | Myotis yumanensis (Yuma myotis) |
| pkl | Pipistrellus kuhlii (Kuhl's pipistrelle) |
| efus | Eptesicus fuscus (big brown bat) |
| mna | Miniopterus natalensis (Natal long-fingered bat) |
| dro | Desmodus rotundus (common vampire bat) |
| shon | Sturnira hondurensis |
| ajm | Artibeus jamaicensis (Jamaican fruit-eating bat) |
| pdic | Phyllostomus discolor (pale spear-nosed bat) |
| phas | Phyllostomus hastatus (greater spear-nosed bat) |
| mmf | Molossus molossus (Pallas's mastiff bat) |
| ppam | Pteronotus mesoamericanus (Parnell's mustached bat) |
| hai | Hipposideros armiger (great roundleaf bat) |
| rfq | Rhinolophus ferrumequinum (greater horseshoe bat) |
| pale | Pteropus alecto (black flying fox) |
| pgig | Pteropus vampyrus (Indian flying fox) |
| pvp | Pteropus vampyrus (large flying fox) |
| ray | Rousettus aegyptiacus (Egyptian rousette) |
| tod | Talpa occidentalis (Iberian mole) |
| sara | Sorex araneus (European shrew) |
| sfum | Sorex fumeus (smoky shrew) |
| setr | Suncus etruscus (white-toothed pygmy shrew) |
| lav | Loxodonta africana (African savanna elephant) |
| tmu | Trichechus manatus latirostris (Florida manatee) |
| etf | Echinops telfairi (small Madagascar hedgehog) |
| dnm | Dasypus novemcinctus (nine-banded armadillo) |
| mdo | Monodelphis domestica (gray short-tailed opossum) |
| gas | Gracilinanus agilis (agile gracile opossum) |
| shr | Sarcophilus harrisii (Tasmanian devil) |
| afz | Antechinus flavipes (yellow-footed antechinus) |
| pcw | Phascolarctos cinereus (koala) |
| tvp | Trichosurus vulpecula (common brushtail) |
| pbrv | Petaurus breviceps papuanus (sugar glider) |
| oaa | Ornithorhynchus anatinus (platypus) |
| tacu | Tachyglossus aculeatus (Australian echidna) |
| aacu | Anas acuta (northern pintail) |
| tgu | Taeniopygia guttata (zebra finch) |
| lsr | Lonchura striata (white-rumped munia) |
| atrc | Agelaius tricolor (tricolored blackbird) |
| acoe | Aphelocoma coerulescens (scrub jay) |
| ccic | Cinclus cinclus (white-throated dipper) |
| bbut | Buteo buteo (common buzzard) |
| cboy | Ciconia boyciana (Oriental stork) |
| cnic | Caloenas nicobarica (Nicobar pigeon) |
| asn | Alligator sinensis (Chinese alligator) |
| amj | Alligator mississippiensis (American alligator) |
| ciz | Carettochelys insculpta (pitted-shelled turtle) |
| ccay | Caretta caretta (Loggerhead turtle) |
| lkp | Lepidochelys kempii (Atlantic ridley) |
| nds | Natator depressus (flatback sea turtle) |
| dcc | Dermochelys coriacea (leatherback sea turtle) |
| cpic | Chrysemys picta (western painted turtle) |
| mrv | Mauremys reevesii (Reeves's turtle) |
| emq | Emydura macquarii macquarii (eastern short-necked turtle) |
| acs | Anolis carolinensis (green anole) |
| asao | Anolis sagrei ordinatus (Brown anole) |
| pvt | Pogona vitticeps (central bearded dragon) |
| sund | Sceloporus undulatus (fence lizard) |
| pbi | Python bivittatus (Burmese python) |
| pmur | Protobothrops mucrosquamatus (Taiwan habu) |
| ctig | Crotalus tigris (Tiger rattlesnake) |
| pgut | Pantherophis guttatus (corn snake) |
| pcae | Pituophis catenifer annectens (San Diego gophersnake) |
| apri | Ahaetulla prasina (Asian vine snake) |
| vko | Varanus komodoensis (Komodo dragon) |
| pmua | Podarcis muralis (common wall lizard) |
| praf | Podarcis raffonei (Aeolian wall lizard) |
| hcg | Hemicordylus capensis (graceful crag lizard) |
| gja | Gekko japonicus (Schlegel's Japanese gecko) |
| stow | Sphaerodactylus townsendi (Townsend's least gecko) |
| emc | Eublepharis macularius (Leopard gecko) |
| xla | Xenopus laevis (African clawed frog) |
| xtr | Xenopus tropicalis (tropical clawed frog) |
| rtem | Rana temporaria (common frog) |
| pads | Pyxicephalus adspersus (African bullfrog) |
| bbuf | Bufo bufo (common toad) |
| bgar | Bufo gargarizans (Asiatic toad) |
| dtc | Dendrobates tinctorius (dyeing poison frog) |
| pwl | Pleurodeles waltl (Iberian ribbed newt) |
| muo | Microcaecilia unicolor |
| gsh | Geotrypetes seraphini (Gaboon caecilian) |
| dre | Danio rerio (zebrafish) |
| srx | Sinocyclocheilus rhinocerous |
| sanh | Sinocyclocheilus anshuiensis |
| sgh | Sinocyclocheilus grahami (golden-line barbel) |
| ccar | Cyprinus carpio (common carp) |
| caua | Carassius auratus (goldfish) |
| cgib | Carassius gibelio (silver crucian carp) |
| ptet | Puntigrus tetrazona (Sumatra barb) |
| grf | Garra rufa (doctor fish) |
| omc | Onychostoma macrolepis |
| pprm | Pimephales promelas (fathead minnow) |
| rkg | Rhinichthys klamathensis goyatoka (western speckled dace) |
| mamb | Megalobrama amblycephala (Wuchang bream) |
| cide | Ctenopharyngodon idella (grass carp) |
| cery | Chanodichthys erythropterus (predatory carp) |
| masi | Myxocyprinus asiaticus (Chinese sucker) |
| manu | Misgurnus anguillicaudatus (oriental weatherfish) |
| pdab | Paramisgurnus dabryanus (large-scale loach) |
| ipu | Ictalurus punctatus (channel catfish) |
| phyp | Pangasianodon hypophthalmus (striped catfish) |
| smeo | Silurus meridionalis (southern catfish) |
| tfd | Tachysurus fulvidraco (yellow catfish) |
| cgar | Clarias gariepinus (North African catfish) |
| ngra | Neoarius graeffei (lesser salmon catfish) |
| trn | Trichomycterus rosablanca |
| amex | Astyanax mexicanus (Mexican tetra) |
| cmao | Colossoma macropomum (tambaqui) |
| eee | Electrophorus electricus (electric eel) |
| char | Clupea harengus (Atlantic herring) |
| spil | Sardina pilchardus (sardine) |
| asad | Alosa sapidissima (American shad) |
| tru | Takifugu rubripes (torafugu) |
| tfs | Takifugu flavidus (sansaifugu) |
| ncc | Notothenia coriiceps (black rockcod) |
| tben | Trematomus bernacchii (emerald rockcod) |
| pgeo | Pseudochaenichthys georgianus (South Georgia icefish) |
| gacu | Gymnodraco acuticeps |
| emac | Eleginops maclovinus (Patagonian blennie) |
| ely | Epinephelus lanceolatus (giant grouper) |
| efo | Epinephelus fuscoguttatus (brown-marbled grouper) |
| plep | Plectropomus leopardus (leopard coralgrouper) |
| sluc | Sander lucioperca (pikeperch) |
| ecra | Etheostoma cragini (Arkansas darter) |
| esp | Etheostoma spectabile (orangethroat darter) |
| pflv | Perca flavescens (yellow perch) |
| gat | Gasterosteus aculeatus (three-spined stickleback) |
| afb | Anoplopoma fimbria (sablefish) |
| clum | Cyclopterus lumpus (lumpfish) |
| pswi | Pseudoliparis swirei (Mariana hadal snailfish) |
| cana | Clinocottus analis (woolly sculpin) |
| cve | Cebidichthys violaceus (monkeyface prickleback) |
| msam | Micropterus salmoides (largemouth bass) |
| schu | Siniperca chuatsi (mandarin fish) |
| earm | Enoplosus armatus (old wife) |
| cud | Cheilinus undulatus (humphead wrasse) |
| spul | Semicossyphus pulcher (California sheephead) |
| lmix | Labrus mixtus (cuckoo wrasse) |
| htc | Halichoeres trimaculatus (threespot wrasse) |
| alat | Acanthopagrus latus (yellowfin seabream) |
| astr | Antennarius striatus (striated frogfish) |
| pklu | Pempheris klunzingeri |
| lco | Larimichthys crocea (large yellow croaker) |
| mze | Maylandia zebra (zebra mbuna) |
| onl | Oreochromis niloticus (Nile tilapia) |
| oau | Oreochromis aureus (blue tilapia) |
| ola | Oryzias latipes (Japanese medaka) |
| oml | Oryzias melastigma (Indian medaka) |
| csai | Cololabis saira (Pacific saury) |
| xma | Xiphophorus maculatus (southern platyfish) |
| xco | Xiphophorus couchianus (Monterrey platyfish) |
| xhe | Xiphophorus hellerii (green swordtail) |
| pret | Poecilia reticulata (guppy) |
| pfor | Poecilia formosa (Amazon molly) |
| plai | Poecilia latipinna (sailfin molly) |
| pmei | Poecilia mexicana (shortfin molly) |
| gaf | Gambusia affinis (western mosquitofish) |
| pprl | Poeciliopsis prolifica (blackstripe livebearer) |
| cvg | Cyprinodon variegatus (sheepshead minnow) |
| ctul | Cyprinodon tularosa (White Sands pupfish) |
| gmu | Girardinichthys multiradiatus (darkedged splitfin) |
| nfu | Nothobranchius furzeri (turquoise killifish) |
| alim | Austrofundulus limnaeus (annual killifish) |
| nwh | Nematolebias whitei (Rio pearlfish) |
| ltu | Leuresthes tenuis (California grunion) |
| mcep | Mugil cephalus (flathead mullet) |
| eja | Embiotoca jacksoni (black perch) |
| bfre | Brachyistius frenatus (kelp perch) |
| lcf | Lates calcarifer (barramundi perch) |
| csem | Cynoglossus semilaevis (tongue sole) |
| pov | Paralichthys olivaceus (Japanese flounder) |
| ssen | Solea senegalensis (Senegalese sole) |
| ssoe | Solea solea (common sole) |
| hhip | Hippoglossus hippoglossus (Atlantic halibut) |
| hsp | Hippoglossus stenolepis (Pacific halibut) |
| pplt | Pleuronectes platessa (European plaice) |
| smau | Scophthalmus maximus (turbot) |
| sdu | Seriola dumerili (greater amberjack) |
| slal | Seriola lalandi dorsalis (Yellowtail amberjack) |
| xgl | Xiphias gladius (swordfish) |
| hcq | Hippocampus comes (tiger tail seahorse) |
| sscv | Syngnathus scovelli (Gulf pipefish) |
| sbia | Syngnathoides biaculeatus (alligator pipefish) |
| pee | Phycodurus eques (leafy seadragon) |
| ptao | Phyllopteryx taeniolatus (common seadragon) |
| bpec | Boleophthalmus pectinirostris (great blue-spotted mudskipper) |
| eny | Eucyclogobius newberryi (tidewater goby) |
| malb | Monopterus albus (swamp eel) |
| bspl | Betta splendens (Siamese fighting fish) |
| sjo | Scomber japonicus (chub mackerel) |
| ssco | Scomber scombrus (Atlantic mackerel) |
| tty | Thunnus thynnus (Atlantic bluefin tuna) |
| gmh | Gadus morhua (Atlantic cod) |
| sasa | Salmo salar (Atlantic salmon) |
| otw | Oncorhynchus tshawytscha (Chinook salmon) |
| omy | Oncorhynchus mykiss (rainbow trout) |
| ogo | Oncorhynchus gorbuscha (pink salmon) |
| oki | Oncorhynchus kisutch (coho salmon) |
| oke | Oncorhynchus keta (chum salmon) |
| omm | Oncorhynchus masou masou (cherry salmon) |
| ocla | Oncorhynchus clarkii lewisi (westslope cutthroat trout) |
| salp | Salvelinus sp. IW2-2015 (Arctic char) |
| snh | Salvelinus namaycush (lake trout) |
| sfon | Salvelinus fontinalis (brook trout) |
| cclu | Coregonus clupeaformis (lake whitefish) |
| els | Esox lucius (northern pike) |
| oep | Osmerus eperlanus (European smelt) |
| sfm | Scleropages formosus (Asian bonytongue) |
| pki | Paramormyrops kingsleyae |
| aang | Anguilla anguilla (European eel) |
| arot | Anguilla rostrata (American eel) |
| ccog | Conger conger (European conger) |
| pspa | Polyodon spathula (Mississippi paddlefish) |
| arut | Acipenser ruthenus (sterlet) |
| lcm | Latimeria chalumnae (coelacanth) |
| cpun | Chiloscyllium punctatum (brownbanded bambooshark) |
| haka | Hemitrygon akajei (red stingray) |
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| Reaction |
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| Compound |
| C01176 | 17alpha-Hydroxyprogesterone |
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| LinkDB |
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