KEGG   MODULE: M00128
Entry
M00128            Pathway   Module                                 
Name
Ubiquinone biosynthesis, eukaryotes, 4-hydroxybenzoate + polyprenyl-PP => ubiquinol
Definition
K06125 K06126 K00591 -- -- K06127 K06134 K00591
Diagram
M00128

Orthology
K06125  
COQ2; 4-hydroxybenzoate polyprenyltransferase [EC:2.5.1.39] [RN:R05000]
K06126  
COQ6; ubiquinone biosynthesis monooxygenase Coq6 [EC:1.14.13.-] [RN:R08770]
K00591  
COQ3; polyprenyldihydroxybenzoate methyltransferase / 3-demethylubiquinol 3-O-methyltransferase [EC:2.1.1.114 2.1.1.64] [RN:R08771 R12657]
K06127  
COQ5; 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase [EC:2.1.1.201] [RN:R09737]
K06134  
COQ7; 3-demethoxyubiquinol 3-hydroxylase [EC:1.14.99.60] [RN:R12067]
Class
Pathway modules; Metabolism of cofactors and vitamins; Cofactor and vitamin metabolism
Pathway
map00130  Ubiquinone and other terpenoid-quinone biosynthesis
map01240  Biosynthesis of cofactors
map01100  Metabolic pathways
Reaction
Compound
C00156  4-Hydroxybenzoate
C05847  all-trans-Polyprenyl diphosphate
C05848  4-Hydroxy-3-polyprenylbenzoate
C17554  3,4-Dihydroxy-5-polyprenylbenzoate
C17559  3-Methoxy-4-hydroxy-5-polyprenylbenzoate
C17552  2-Polyprenyl-6-methoxyphenol
C19858  2-Methoxy-6-all-trans-polyprenyl-1,4-benzoquinol
C19859  6-Methoxy-3-methyl-2-all-trans-polyprenyl-1,4-benzoquinol
C21860  3-Demethylubiquinol
C00390  Ubiquinol
Reference
  Authors
Kawamukai M
  Title
Biosynthesis of coenzyme Q in eukaryotes.
  Journal
Biosci Biotechnol Biochem 80:23-33 (2016)
DOI:10.1080/09168451.2015.1065172
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