KEGG   MODULE: M00830
Entry
M00830            Pathway   Module                                 

Name
Neocarzinostatin naphthoate moiety biosynthesis, malonyl-CoA => 2-hydroxy-5-methyl-1-naphthoate => 2-hydroxy-7-methoxy-5-methyl-1-naphthoyl-CoA
Definition
K20422 K20420 K20421 K20423
Diagram
M00830

Orthology
K20422  
ncsB; neocarzinostatin naphthoate synthase [EC:2.3.1.237] [RN:R11125]
K20420  
ncsB3; 2-hydroxy-5-methyl-1-naphthoate 7-hydroxylase [EC:1.14.15.31] [RN:R10796]
K20421  
ncsB1; 2,7-dihydroxy-5-methyl-1-naphthoate 7-O-methyltransferase [EC:2.1.1.303] [RN:R10963]
K20423  
ncsB2; 2-hydroxy-7-methoxy-5-methyl-1-naphthoate---CoA ligase [EC:6.2.1.43] [RN:R10771]
Class
Pathway modules; Biosynthesis of terpenoids and polyketides; Enediyne biosynthesis
Pathway
map01059  Biosynthesis of enediyne antibiotics
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Reaction
Compound
C00083  Malonyl-CoA
C20856  2-Hydroxy-5-methyl-1-naphthoate
C20857  2,7-Dihydroxy-5-methyl-1-naphthoate
C20841  2-Hydroxy-7-methoxy-5-methyl-1-naphthoate
C20842  2-Hydroxy-7-methoxy-5-methyl-1-naphthoyl-CoA
LinkDB

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