KEGG   MODULE: M00945
Entry
M00945            Pathway   Module                                 
Name
Sanguinarine biosynthesis, (S)-reticuline => sanguinarine
Definition
K00307 K21070 K13395 K13396 K21692 K21693 K22089
Diagram
M00945  Sanguinarine biosynthesis, (S)-reticuline => sanguinarine
M00945

Class
Pathway modules; Biosynthesis of other secondary metabolites; Biosynthesis of phytochemical compounds
Pathway
map00950  Isoquinoline alkaloid biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Orthology
K00307  
reticuline oxidase [EC:1.21.3.3] [RN:R03831]
K21070  
(S)-cheilanthifoline synthase [EC:1.14.19.65] [RN:R03834]
K13395  
(S)-stylopine synthase [EC:1.14.19.64] [RN:R04690]
K13396  
(S)-tetrahydroprotoberberine N-methyltransferase [EC:2.1.1.122] [RN:R04691]
K21692  
methyltetrahydroprotoberberine 14-monooxygenase [EC:1.14.14.97] [RN:R04700]
K21693  
protopine 6-monooxygenase [EC:1.14.14.98] [RN:R04699]
K22089  
tetrahydroprotoberberine oxidase [EC:1.3.3.8] [RN:R04703]
Complete
psom  Papaver somniferum (opium poppy)
Reaction
R03831  
R03834  
R04690  
R04691  
R04700  
R04699  
R04701  
R04703  
Compound
C02105  (S)-Reticuline
C02106  (S)-Scoulerine
C05174  (S)-Cheilanthifoline
C05175  Stylopine
C06163  (S)-cis-N-Methylstylopine
C05189  Protopine
C05190  6-Hydroxyprotopine
C05191  Dihydrosanguinarine
C06162  Sanguinarine
Reference
PMID:24671624
  Authors
Beaudoin GA, Facchini PJ.
  Title
Benzylisoquinoline alkaloid biosynthesis in opium poppy.
  Journal
Planta 240:19-32 (2014)
DOI:10.1007/s00425-014-2056-8
LinkDB

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