| Entry |
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| Name |
CDH1-reduced expression to beta-catenin signaling pathway
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| Definition |
CDH1* // CTNNB1 -> TCF/LEF => (MYC,CCND1) |
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| Expanded |
999v1 // 1499 -> (6932,83439,6934,51176) => (4609,595) |
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| Class |
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| Type |
Variant
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| Pathway |
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| Disease |
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| Gene |
| 1499 | CTNNB1; catenin beta 1 |
| 6932 | TCF7; transcription factor 7 |
| 83439 | TCF7L1; transcription factor 7 like 1 |
| 6934 | TCF7L2; transcription factor 7 like 2 |
| 51176 | LEF1; lymphoid enhancer binding factor 1 |
| 4609 | MYC; MYC proto-oncogene, bHLH transcription factor |
|
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| Variant |
999v1 (CDH1*) CDH1 reduced expression
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| Reference |
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| Authors |
Kondo T, Ezzat S, Asa SL. |
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| Title |
Pathogenetic mechanisms in thyroid follicular-cell neoplasia. |
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| Journal |
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| Reference |
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| Authors |
Rocha AS, Soares P, Seruca R, Maximo V, Matias-Guiu X, Cameselle-Teijeiro J, Sobrinho-Simoes M |
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| Title |
Abnormalities of the E-cadherin/catenin adhesion complex in classical papillary thyroid carcinoma and in its diffuse sclerosing variant. |
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| Journal |
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| Reference |
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| Authors |
Van Aken E, De Wever O, Correia da Rocha AS, Mareel M |
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| Title |
Defective E-cadherin/catenin complexes in human cancer. |
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| Journal |
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| LinkDB |
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