| Entry |
|
|---|
| Name |
HCV Core to ERK signaling pathway
|
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| Definition |
Core -| YWHA -| RAF -> MEK -> ERK |
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| Expanded |
K22271 -| (10971,7529,7531,7532,7533,7534) -| (369,673,5894) -> (5604,5605) -> (5594,5595) |
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| Class |
|
|---|
| Type |
Pathogen
|
|---|
| Pathway |
|
|---|
| Disease |
| H00048 | Hepatocellular carcinoma |
|
|---|
| Gene |
| 10971 | YWHAQ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta |
| 7529 | YWHAB; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta |
| 7531 | YWHAE; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon |
| 7532 | YWHAG; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma |
| 7533 | YWHAH; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta |
| 7534 | YWHAZ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta |
| 369 | ARAF; A-Raf proto-oncogene, serine/threonine kinase |
| 673 | BRAF; B-Raf proto-oncogene, serine/threonine kinase |
| 5894 | RAF1; Raf-1 proto-oncogene, serine/threonine kinase |
| 5604 | MAP2K1; mitogen-activated protein kinase kinase 1 |
| 5605 | MAP2K2; mitogen-activated protein kinase kinase 2 |
| 5594 | MAPK1; mitogen-activated protein kinase 1 |
| 5595 | MAPK3; mitogen-activated protein kinase 3 |
|
|---|
| Perturbant |
| K22271 (Core) | Core; HCV core protein |
|
|---|
| Reference |
|
|---|
| Authors |
Panteva M, Korkaya H, Jameel S |
|---|
| Title |
Hepatitis viruses and the MAPK pathway: is this a survival strategy? |
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| Journal |
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| Reference |
|
|---|
| Authors |
Aoki H, Hayashi J, Moriyama M, Arakawa Y, Hino O |
|---|
| Title |
Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. |
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| Journal |
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| LinkDB |
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