| Entry |
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| Name |
Mutation-caused aberrant Htt to electron transfer in Complex III
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| Definition |
HTT* -| CxIII -> CytC |
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| Expanded |
3064v1 -| (7386+4519+1537+7384+7385+(440567,7388)+7381+27089+29796+10975) -> C00524 |
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| Class |
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| Type |
Variant
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| Pathway |
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| Disease |
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| Gene |
| 7386 | UQCRFS1; ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 |
| 7384 | UQCRC1; ubiquinol-cytochrome c reductase core protein 1 |
| 7385 | UQCRC2; ubiquinol-cytochrome c reductase core protein 2 |
| 440567 | UQCRHL; ubiquinol-cytochrome c reductase hinge protein like |
| 7388 | UQCRH; ubiquinol-cytochrome c reductase hinge protein |
| 7381 | UQCRB; ubiquinol-cytochrome c reductase binding protein |
| 27089 | UQCRQ; ubiquinol-cytochrome c reductase complex III subunit VII |
| 29796 | UQCR10; ubiquinol-cytochrome c reductase, complex III subunit X |
| 10975 | UQCR11; ubiquinol-cytochrome c reductase, complex III subunit XI |
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| Variant |
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| Metabolite |
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| Reference |
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| Authors |
Gu M, Gash MT, Mann VM, Javoy-Agid F, Cooper JM, Schapira AH |
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| Title |
Mitochondrial defect in Huntington's disease caudate nucleus. |
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| Journal |
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| Reference |
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| Authors |
Labbadia J, Morimoto RI |
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| Title |
Huntington's disease: underlying molecular mechanisms and emerging concepts. |
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| Journal |
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| Reference |
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| Authors |
Chakraborty J, Rajamma U, Mohanakumar KP |
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| Title |
A mitochondrial basis for Huntington's disease: therapeutic prospects. |
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| Journal |
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| Reference |
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| Authors |
Golpich M, Amini E, Mohamed Z, Azman Ali R, Mohamed Ibrahim N, Ahmadiani A |
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| Title |
Mitochondrial Dysfunction and Biogenesis in Neurodegenerative diseases: Pathogenesis and Treatment. |
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| Journal |
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| LinkDB |
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