Entry |
|
Name |
Mutation-caused aberrant Htt to TNF-JNK signaling pathway
|
Definition |
HTT* -> MLK2 -> MKK7 -> JNK |
Expanded |
3064v1 -> 4294 -> 5609 -> (5599,5601,5602) |
Class |
|
Type |
Variant
|
Pathway |
|
Disease |
|
Gene |
4294 | MAP3K10; mitogen-activated protein kinase kinase kinase 10 |
5609 | MAP2K7; mitogen-activated protein kinase kinase 7 |
5599 | MAPK8; mitogen-activated protein kinase 8 |
5601 | MAPK9; mitogen-activated protein kinase 9 |
5602 | MAPK10; mitogen-activated protein kinase 10 |
|
Variant |
|
Reference |
|
Authors |
Borrell-Pages M, Zala D, Humbert S, Saudou F |
Title |
Huntington's disease: from huntingtin function and dysfunction to therapeutic strategies. |
Journal |
|
Reference |
|
Authors |
Bowles KR, Jones L |
Title |
Kinase signalling in Huntington's disease. |
Journal |
|
LinkDB |
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