| Entry |
|
| Name |
SARS-CoV-2 S to classical pathway of complement cascade
|
| Definition |
S -> (IgG,IgM) -> ((C1QA,C1QB,C1QC)+C1R+C1S)) |
| Expanded |
K24152 -> 102723407 -> ((712,713,714)+715+716)) |
| Class |
|
| Type |
Pathogen
|
| Pathway |
|
| Disease |
|
| Gene |
| 102723407 | IGH; immunoglobulin heavy variable 4-38-2-like |
| 712 | C1QA; complement C1q A chain |
| 713 | C1QB; complement C1q B chain |
| 714 | C1QC; complement C1q C chain |
|
| Perturbant |
| K24152 (S) | S; SARS coronavirus spike glycoprotein |
|
| Reference |
|
| Authors |
Noris M, Benigni A, Remuzzi G |
| Title |
The case of complement activation in COVID-19 multiorgan impact. |
| Journal |
|
| Reference |
|
| Authors |
Jodele S, Kohl J |
| Title |
Tackling COVID-19 infection through complement-targeted immunotherapy. |
| Journal |
|
| Reference |
|
| Authors |
Chauhan AJ, Wiffen LJ, Brown TP |
| Title |
COVID-19: A collision of complement, coagulation and inflammatory pathways. |
| Journal |
|
| LinkDB |
|