Entry |
|
Symbol |
IGH, IGH@, IGHV4, IGHV4-30, IGHV4-38-2, IGHV4-39, IGHV4-b, IGVH, IGVH4-39, IGVH4-b, IGVH4b, IgA, IgT, ighv
|
Name |
(RefSeq) immunoglobulin heavy variable 4-38-2-like
|
KO |
K06856 | immunoglobulin heavy chain |
|
Organism |
|
Pathway |
hsa04072 | Phospholipase D signaling pathway |
hsa04613 | Neutrophil extracellular trap formation |
hsa04650 | Natural killer cell mediated cytotoxicity |
hsa04662 | B cell receptor signaling pathway |
hsa04664 | Fc epsilon RI signaling pathway |
hsa04666 | Fc gamma R-mediated phagocytosis |
hsa04672 | Intestinal immune network for IgA production |
hsa05130 | Pathogenic Escherichia coli infection |
hsa05150 | Staphylococcus aureus infection |
hsa05202 | Transcriptional misregulation in cancer |
|
Network |
|
Element |
N00487 | BCR-PLCG-Calcineurin signaling pathway |
N01090 | IGG-FCGR-RAC signaling pathway |
N01314 | SARS-CoV-2 S to classical pathway of complement cascade |
N01695 | BCR-BCAP/CD19-PI3K signaling pathway |
|
Brite |
KEGG Orthology (KO) [BR:hsa00001]
09130 Environmental Information Processing
09132 Signal transduction
04064 NF-kappa B signaling pathway
102723407 (IGH)
04020 Calcium signaling pathway
102723407 (IGH)
04072 Phospholipase D signaling pathway
102723407 (IGH)
04151 PI3K-Akt signaling pathway
102723407 (IGH)
09140 Cellular Processes
09141 Transport and catabolism
04145 Phagosome
102723407 (IGH)
09150 Organismal Systems
09151 Immune system
04640 Hematopoietic cell lineage
102723407 (IGH)
04613 Neutrophil extracellular trap formation
102723407 (IGH)
04650 Natural killer cell mediated cytotoxicity
102723407 (IGH)
04662 B cell receptor signaling pathway
102723407 (IGH)
04664 Fc epsilon RI signaling pathway
102723407 (IGH)
04666 Fc gamma R-mediated phagocytosis
102723407 (IGH)
04672 Intestinal immune network for IgA production
102723407 (IGH)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
102723407 (IGH)
09172 Infectious disease: viral
05171 Coronavirus disease - COVID-19
102723407 (IGH)
05169 Epstein-Barr virus infection
102723407 (IGH)
09171 Infectious disease: bacterial
05130 Pathogenic Escherichia coli infection
102723407 (IGH)
05135 Yersinia infection
102723407 (IGH)
05150 Staphylococcus aureus infection
102723407 (IGH)
05152 Tuberculosis
102723407 (IGH)
09174 Infectious disease: parasitic
05146 Amoebiasis
102723407 (IGH)
05140 Leishmaniasis
102723407 (IGH)
05143 African trypanosomiasis
102723407 (IGH)
09163 Immune disease
05310 Asthma
102723407 (IGH)
05322 Systemic lupus erythematosus
102723407 (IGH)
05323 Rheumatoid arthritis
102723407 (IGH)
05320 Autoimmune thyroid disease
102723407 (IGH)
05330 Allograft rejection
102723407 (IGH)
05340 Primary immunodeficiency
102723407 (IGH)
09166 Cardiovascular disease
05414 Dilated cardiomyopathy
102723407 (IGH)
05416 Viral myocarditis
102723407 (IGH)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:hsa04131]
102723407 (IGH)
Membrane trafficking [BR:hsa04131]
Endocytosis
Phagocytosis
Opsonins
102723407 (IGH)
|
SSDB |
|
Motif |
|
Other DBs |
|
LinkDB |
|
Position |
14
|
AA seq |
217 aa
MDLLCKNMKHLWFFLLLVAAPRWVLSQVQLQESGPGLVKPSETLSLTCTVSGYSISSGYY
WGWIRQPPGKGLEWIGSIYHSGSTYYNPSLKSRVTISVDTSKNQFSLKLSSVTAADTAVY
YCARDTVRGGECEPRHKPPCREAEGTGAGAAHGQQGARGAHGIQGRVRSRCRVSGACSSS
QRSSSPSSPAPQLSVEVLFLYCLWFYFLTSLCQERKE |
NT seq |
654 nt +upstreamnt +downstreamnt
atggacctcctgtgcaagaacatgaagcacctgtggtttttcctcctgctggtggcagct
cccagatgggtcctgtcccaggtgcagctgcaggagtcgggcccaggactggtgaagcct
tcggagaccctgtccctcacctgcactgtctctggttactccatcagcagtggttactac
tggggctggatccggcagcccccagggaaggggctggagtggattgggagtatctatcat
agtgggagcacctactacaacccgtccctcaagagtcgagtcaccatatcagtagacacg
tccaagaaccagttctccctgaagctgagctctgtgaccgccgcagacacggccgtgtat
tactgtgcgagagacacagtgaggggaggtgagtgtgagcccagacacaaacctccctgc
agggaggctgaggggaccggcgcaggtgcagctcacggccagcagggggcgcgcggagct
cacggaatacaaggccgggtcaggagcaggtgcagggtgagcggggcttgctcatcttct
cagagatcatcatctccctcctcgccagcacctcagctttccgtagaggtcctctttctt
tattgtctgtggttctacttcctcacatccttgtgccaggaaagaaaggagtaa |