ORTHOLOGY: K24152 Help
Entry
Symbol
S
Name
SARS coronavirus spike glycoprotein
Pathway
Network
Element
N01307 SARS-CoV-2 S to AngII-AT1R-NOX2 signaling pathway
N01312 SARS-CoV-2 S to lectin pathway of complement cascade
N01314 SARS-CoV-2 S to classical pathway of complement cascade
N01316 SARS-CoV-2 S/N to lectin pathway of coagulation cascade
Brite
KEGG Orthology (KO) [BR:ko00001 ]
09120 Genetic Information Processing
09125 Information processing in viruses
03230 Viral genome structure
K24152 S; SARS coronavirus spike glycoprotein
03262 Virion - Coronavirus
K24152 S; SARS coronavirus spike glycoprotein
09160 Human Diseases
09172 Infectious disease: viral
05171 Coronavirus disease - COVID-19
K24152 S; SARS coronavirus spike glycoprotein
09180 Brite Hierarchies
09185 Viral protein families
03200 Viral proteins
K24152 S; SARS coronavirus spike glycoprotein
03210 Viral fusion proteins
K24152 S; SARS coronavirus spike glycoprotein
Viral proteins [BR:ko03200 ]
+ssRNA viruses
Coronavirus
K24152 S; SARS coronavirus spike glycoprotein
Viral fusion proteins [BR:ko03210 ]
Class I fusion proteins
Coronaviridae
K24152 S; SARS coronavirus spike glycoprotein
Virus entry [br03220.html ]
Viral entry protein - human receptor protein interactions
K24152
BRITE hierarchy
Genes
Virus taxonomy UniProt
Reference
Authors
Rota PA, Oberste MS, Monroe SS, Nix WA, Campagnoli R, Icenogle JP, Penaranda S, Bankamp B, Maher K, Chen MH, Tong S, Tamin A, Lowe L, Frace M, DeRisi JL, Chen Q, Wang D, Erdman DD, Peret TC, Burns C, Ksiazek TG, Rollin PE, Sanchez A, Liffick S, Holloway B, Limor J, McCaustland K, Olsen-Rasmussen M, Fouchier R, Gunther S, Osterhaus AD, Drosten C, Pallansch MA, Anderson LJ, Bellini WJ
Title
Characterization of a novel coronavirus associated with severe acute respiratory syndrome.
Journal
Sequence
Reference
Authors
Li W, Moore MJ, Vasilieva N, Sui J, Wong SK, Berne MA, Somasundaran M, Sullivan JL, Luzuriaga K, Greenough TC, Choe H, Farzan M
Title
Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus.
Journal
Reference
Authors
Wu F, Zhao S, Yu B, Chen YM, Wang W, Song ZG, Hu Y, Tao ZW, Tian JH, Pei YY, Yuan ML, Zhang YL, Dai FH, Liu Y, Wang QM, Zheng JJ, Xu L, Holmes EC, Zhang YZ
Title
A new coronavirus associated with human respiratory disease in China.
Journal
Sequence
Reference
Authors
Hoffmann M, Kleine-Weber H, Schroeder S, Kruger N, Herrler T, Erichsen S, Schiergens TS, Herrler G, Wu NH, Nitsche A, Muller MA, Drosten C, Pohlmann S
Title
SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor.
Journal
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