| Entry |
|
|---|
| Name |
Metals to HTF-1 signaling pathway
|
|---|
| Definition |
Metals -> ROS -> HIF1A == ARNT => VEGFA |
|---|
| Expanded |
(C06269,C01413,C19171,C06268,C06696,C00023,C00291) -> C22381 -> 3091 == 405 => 7422 |
|---|
| Class |
|
|---|
| Type |
Env factor
|
|---|
| Pathway |
| hsa05208 | Chemical carcinogenesis - reactive oxygen species |
|
|---|
| Disease |
| H00014 | Non-small cell lung cancer |
| H00048 | Hepatocellular carcinoma |
|
|---|
| Gene |
| 3091 | HIF1A; hypoxia inducible factor 1 subunit alpha |
| 405 | ARNT; aryl hydrocarbon receptor nuclear translocator |
| 7422 | VEGFA; vascular endothelial growth factor A |
|
|---|
| Perturbant |
|
|---|
| Metabolite |
| C22381 | Reactive oxygen species |
|
|---|
| Reference |
|
|---|
| Authors |
Nourazarian AR, Kangari P, Salmaninejad A |
|---|
| Title |
Roles of oxidative stress in the development and progression of breast cancer. |
|---|
| Journal |
|
|---|
| Reference |
|
|---|
| Authors |
Kirtonia A, Sethi G, Garg M |
|---|
| Title |
The multifaceted role of reactive oxygen species in tumorigenesis. |
|---|
| Journal |
|
|---|
| Reference |
|
|---|
| Authors |
Kumari S, Badana AK, G MM, G S, Malla R |
|---|
| Title |
Reactive Oxygen Species: A Key Constituent in Cancer Survival. |
|---|
| Journal |
|
|---|
| Reference |
|
|---|
| Authors |
Assi M |
|---|
| Title |
The differential role of reactive oxygen species in early and late stages of cancer. |
|---|
| Journal |
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|---|
| LinkDB |
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