KEGG   NETWORK: N01529
Entry
N01529                      Network                                
Name
Recruitment and formation of the MCC
Definition
AURKB -- NDC80 == MPS1 -- KNL1 == (BUB1+BUB3+BUBR1) == (MAD1+MAD2) -> KNL1+MCC
  Expanded
9212 -- 10403 == 7272 -- 57082 == (699+9184+701) == (8379+4085) -> 57082+(4085+701+9184+991)
Class
nt06515 Regulation of kinetochore-microtubule interactions
Type
Reference
Pathway
hsa04110 Cell cycle   
Gene
9212  AURKB; aurora kinase B
10403  NDC80; NDC80 kinetochore complex component
7272  TTK; TTK protein kinase
57082  KNL1; kinetochore scaffold 1
699  BUB1; BUB1 mitotic checkpoint serine/threonine kinase
9184  BUB3; BUB3 mitotic checkpoint protein
701  BUB1B; BUB1 mitotic checkpoint serine/threonine kinase B
8379  MAD1L1; mitotic arrest deficient 1 like 1
4085  MAD2L1; mitotic arrest deficient 2 like 1
991  CDC20; cell division cycle 20
Reference
PMID:30909555
  Authors
Dou Z, Prifti DK, Gui P, Liu X, Elowe S, Yao X
  Title
Recent Progress on the Localization of the Spindle Assembly Checkpoint Machinery to Kinetochores.
  Journal
Cells 8:E278 (2019)
DOI:10.3390/cells8030278
Reference
PMID:25917595
  Authors
Stukenberg PT, Burke DJ
  Title
Connecting the microtubule attachment status of each kinetochore to cell cycle arrest through the spindle assembly checkpoint.
  Journal
Chromosoma 124:463-80 (2015)
DOI:10.1007/s00412-015-0515-z
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