KEGG T01001: 5501

Homo sapiens (human): 5501

Entry

5501              CDS       T01001

Symbol

PPP1CC, PP-1G, PP1C, PPP1G

Name

(RefSeq) protein phosphatase 1 catalytic subunit gamma

K06269

serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]

Organism

hsa Homo sapiens (human)

Pathway

hsa03015

mRNA surveillance pathway

hsa04022

cGMP-PKG signaling pathway

hsa04024

cAMP signaling pathway

hsa04114

Oocyte meiosis

hsa04218

Cellular senescence

hsa04261

Adrenergic signaling in cardiomyocytes

hsa04270

Vascular smooth muscle contraction

hsa04390

Hippo signaling pathway

hsa04510

Focal adhesion

hsa04611

Platelet activation

hsa04720

Long-term potentiation

hsa04728

Dopaminergic synapse

hsa04750

Inflammatory mediator regulation of TRP channels

hsa04810

Regulation of actin cytoskeleton

hsa04910

Insulin signaling pathway

hsa04921

Oxytocin signaling pathway

hsa04931

Insulin resistance

hsa05031

Amphetamine addiction

hsa05034

Alcoholism

hsa05168

Herpes simplex virus 1 infection

hsa05205

Proteoglycans in cancer

hsa05415

Diabetic cardiomyopathy

Network

nt06168  Herpes simplex virus 1 (HSV-1)
nt06515  Regulation of kinetochore-microtubule interactions
nt06526  MAPK signaling
nt06544  Neuroactive ligand signaling

Element

N00572

HSV ICP34.5 to PKR-eIF2alpha signaling pathway

N01531

CENPE interaction with NDC80 complex

N01536

Dephosphorylation of kinetochore

N01598

Regulation of GF-RTK-RAS-ERK signaling, MRAS-SHOC2-PP1 holophosphatase

N01905

AC-PKA-HCN signaling

Brite

KEGG Orthology (KO) [BR:hsa00001]
09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    5501 (PPP1CC)
09130 Environmental Information Processing
  09132 Signal transduction
   04390 Hippo signaling pathway
    5501 (PPP1CC)
   04024 cAMP signaling pathway
    5501 (PPP1CC)
   04022 cGMP-PKG signaling pathway
    5501 (PPP1CC)
09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    5501 (PPP1CC)
   04218 Cellular senescence
    5501 (PPP1CC)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    5501 (PPP1CC)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    5501 (PPP1CC)
09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    5501 (PPP1CC)
  09152 Endocrine system
   04910 Insulin signaling pathway
    5501 (PPP1CC)
   04921 Oxytocin signaling pathway
    5501 (PPP1CC)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    5501 (PPP1CC)
   04270 Vascular smooth muscle contraction
    5501 (PPP1CC)
  09156 Nervous system
   04728 Dopaminergic synapse
    5501 (PPP1CC)
   04720 Long-term potentiation
    5501 (PPP1CC)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    5501 (PPP1CC)
09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    5501 (PPP1CC)
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    5501 (PPP1CC)
  09165 Substance dependence
   05031 Amphetamine addiction
    5501 (PPP1CC)
   05034 Alcoholism
    5501 (PPP1CC)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    5501 (PPP1CC)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    5501 (PPP1CC)
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    5501 (PPP1CC)
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:hsa03021]
    5501 (PPP1CC)
   03019 Messenger RNA biogenesis [BR:hsa03019]
    5501 (PPP1CC)
   03041 Spliceosome [BR:hsa03041]
    5501 (PPP1CC)
Enzymes [BR:hsa01000]
3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     5501 (PPP1CC)
Protein phosphatases and associated proteins [BR:hsa01009]
Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    Catalytic subunits
     5501 (PPP1CC)
Transcription machinery [BR:hsa03021]
Eukaryotic type
  RNA polymerase II system
   Other transcription-related factors
    Transcription termination factor
     5501 (PPP1CC)
Messenger RNA biogenesis [BR:hsa03019]
Eukaryotic type
  mRNA processing factors
   3' end processing
    Cleavage and polyadenylation specificity factor (CPSF) complex
     5501 (PPP1CC)
Spliceosome [BR:hsa03041]
Other splicing related proteins
  Spliceosome associated proteins (SAPs)
   Other SAPs
    5501 (PPP1CC)

SSDB

Motif

Pfam:

Metallophos STPPase_N

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

OMIM:

HGNC:

Ensembl:

UniProt:

Structure

LinkDB

Position

12:complement(110708376..110742891)

AA seq 323 aa
MADLDKLNIDSIIQRLLEVRGSKPGKNVQLQENEIRGLCLKSREIFLSQPILLELEAPLK
ICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL
LRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL
QSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVLGWGENDRGVSFTFGAEVVAKFLHKHD
LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAE
KKKPNATRPVTPPRGMITKQAKK

NT seq 972 nt +upstreamnt +downstreamnt
atggcggatttagataaactcaacatcgacagcattatccaacggctgctggaagtgaga
gggtccaagcctggtaagaatgtccagcttcaggagaatgaaatcagaggactgtgctta
aagtctcgtgaaatctttctcagtcagcctatcctactagaacttgaagcaccactcaaa
atatgtggtgacatccatggacaatactatgatttgctgcgactttttgagtacggtggt
ttcccaccagaaagcaactacctgtttcttggggactatgtggacaggggaaagcagtca
ttggagacgatctgcctcttactggcctacaaaataaaatatcctgagaatttttttctt
ctcagagggaaccatgaatgtgccagcatcaacagaatttatggattttatgatgaatgt
aaaagaagatacaacattaaactatggaaaactttcacagactgttttaactgtttaccg
atagcagccatcgtggatgagaagatattctgctgtcatggaggtttatcaccagatctt
caatctatggagcagattcggcgaattatgcgaccaactgatgtaccagatcaaggtctt
ctttgtgatcttttgtggtctgaccccgataaagatgtcttaggctggggtgaaaatgac
agaggagtgtccttcacatttggtgcagaagtggttgcaaaatttctccataagcatgat
ttggatcttatatgtagagcccatcaggtggttgaagatggatatgaattttttgcaaag
aggcagttggtcactctgttttctgcgcccaattattgcggagagtttgacaatgcaggt
gccatgatgagtgtggatgaaacactaatgtgttcttttcagattttaaagcctgcagag
aaaaagaagccaaatgccacgagacctgtaacgcctccaaggggtatgatcacaaagcaa
gcaaagaaatag

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