Entry |
|
Name |
Regulation of GF-RTK-RAS-ERK signaling, MRAS-SHOC2-PP1 holophosphatase
|
Definition |
(MRAS+SHOC2+PP1) -> RAF |
Expanded |
(22808+8036+(5499,5500,5501)) -> (369,673,5894) |
Class |
|
Type |
Reference
|
Pathway |
|
Gene |
22808 | MRAS; muscle RAS oncogene homolog |
8036 | SHOC2; SHOC2 leucine rich repeat scaffold protein |
5499 | PPP1CA; protein phosphatase 1 catalytic subunit alpha |
5500 | PPP1CB; protein phosphatase 1 catalytic subunit beta |
5501 | PPP1CC; protein phosphatase 1 catalytic subunit gamma |
369 | ARAF; A-Raf proto-oncogene, serine/threonine kinase |
673 | BRAF; B-Raf proto-oncogene, serine/threonine kinase |
5894 | RAF1; Raf-1 proto-oncogene, serine/threonine kinase |
|
Reference |
|
Authors |
Pudewell S, Wittich C, Kazemein Jasemi NS, Bazgir F, Ahmadian MR |
Title |
Accessory proteins of the RAS-MAPK pathway: moving from the side line to the front line. |
Journal |
|
Reference |
|
Authors |
Tartaglia M, Aoki Y, Gelb BD |
Title |
The molecular genetics of RASopathies: An update on novel disease genes and new disorders. |
Journal |
|
LinkDB |
|