KEGG NETWORK: N01947

NETWORK: N01947

Entry

N01947                      Network

Name

PTPRS interactions

Definition

(HSPG,PTPRF/D/S,NGL3,SALM3/5,TRKC,LRRTM4,SLITRK) == PTPRS -> (PPFIA,CASKIN+CASK,TRIO)

Expanded

((6382,6383,9672,6385,2817,221914,2719,2239,2262,10082,3339,375790,1306,80781),(5792,5789,5802),94030,(78999,145581),4916,80059,(114798,84631,139065,26050,84189)) == 5802 -> ((8500,8499,8541,8497),(57524,57513+8573),7204)

Class

nt06546 IgSF CAM signaling

Type

Reference

Pathway

hsa04517 IGSF CAM signaling

Gene

6382	SDC1; syndecan 1

6383	SDC2; syndecan 2

9672	SDC3; syndecan 3

6385	SDC4; syndecan 4

2817	GPC1; glypican 1

221914

GPC2; glypican 2

2719	GPC3; glypican 3

2239	GPC4; glypican 4

2262	GPC5; glypican 5

10082

GPC6; glypican 6

3339	HSPG2; heparan sulfate proteoglycan 2

375790

AGRN; agrin

1306	COL15A1; collagen type XV alpha 1 chain

80781

COL18A1; collagen type XVIII alpha 1 chain

5792	PTPRF; protein tyrosine phosphatase receptor type F

5789	PTPRD; protein tyrosine phosphatase receptor type D

5802	PTPRS; protein tyrosine phosphatase receptor type S

94030

LRRC4B; leucine rich repeat containing 4B

78999

LRFN4; leucine rich repeat and fibronectin type III domain containing 4

145581

LRFN5; leucine rich repeat and fibronectin type III domain containing 5

4916	NTRK3; neurotrophic receptor tyrosine kinase 3

80059

LRRTM4; leucine rich repeat transmembrane neuronal 4

114798

SLITRK1; SLIT and NTRK like family member 1

84631

SLITRK2; SLIT and NTRK like family member 2

139065

SLITRK4; SLIT and NTRK like family member 4

26050

SLITRK5; SLIT and NTRK like family member 5

84189

SLITRK6; SLIT and NTRK like family member 6

8500	PPFIA1; PPFI scaffold protein A1

8499	PPFIA2; PPFI scaffold protein A2

8541	PPFIA3; PPFI scaffold protein A3

8497	PPFIA4; PPFI scaffold protein A4

57524

CASKIN1; CASK interacting protein 1

57513

CASKIN2; CASK interacting protein 2

8573	CASK; calcium/calmodulin dependent serine protein kinase

7204	TRIO; trio Rho guanine nucleotide exchange factor

Reference

PMID:15674434

Authors

Chagnon MJ, Uetani N, Tremblay ML

Title

Functional significance of the LAR receptor protein tyrosine phosphatase family in development and diseases.

Journal

Biochem Cell Biol 82:664-75 (2004)
DOI:10.1139/o04-120

Reference

PMID:34966732

Authors

Cornejo F, Cortes BI, Findlay GM, Cancino GI

Title

LAR Receptor Tyrosine Phosphatase Family in Healthy and Diseased Brain.

Journal

Front Cell Dev Biol 9:659951 (2021)
DOI:10.3389/fcell.2021.659951

Reference

PMID:23835198

Authors

Takahashi H, Craig AM

Title

Protein tyrosine phosphatases PTPdelta, PTPsigma, and LAR: presynaptic hubs for synapse organization.

Journal

Trends Neurosci 36:522-34 (2013)
DOI:10.1016/j.tins.2013.06.002

Reference

PMID:34654889

Authors

Pehkonen H, de Curtis I, Monni O

Title

Liprins in oncogenic signaling and cancer cell adhesion.

Journal

Oncogene 40:6406-6416 (2021)
DOI:10.1038/s41388-021-02048-1

Reference

PMID:23916315

Authors

Um JW, Ko J

Title

LAR-RPTPs: synaptic adhesion molecules that shape synapse development.

Journal

Trends Cell Biol 23:465-75 (2013)
DOI:10.1016/j.tcb.2013.07.004

Reference

PMID:27017006

Authors

Han KA, Jeon S, Um JW, Ko J

Title

Emergent Synapse Organizers: LAR-RPTPs and Their Companions.

Journal

Int Rev Cell Mol Biol 324:39-65 (2016)
DOI:10.1016/bs.ircmb.2016.01.002

LinkDB

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