REACTION: R00941
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Entry
R00941 Reaction
Name
10-formyltetrahydrofolate:NADP+ oxidoreductase
Definition
10-Formyltetrahydrofolate + NADP+ + H2O <=> Tetrahydrofolate + CO2 + NADPH + H+
Equation
C00234
+
C00006
+
C00001
<=>
C00101
+
C00011
+
C00005
+
C00080
Reaction class
RC00001
C00005_C00006
RC00026
C00101_C00234
Enzyme
1.5.1.6
Pathway
rn00670
One carbon pool by folate
rn01100
Metabolic pathways
Brite
Enzymatic reactions [BR:
br08201
]
1. Oxidoreductase reactions
1.5 Acting on the CH-NH group of donors
1.5.1 With NAD+ or NADP+ as acceptor
1.5.1.6
R00941 10-Formyltetrahydrofolate + NADP+ + H2O <=> Tetrahydrofolate + CO2 + NADPH + H+
BRITE hierarchy
Orthology
K00289
formyltetrahydrofolate dehydrogenase [EC:
1.5.1.6
]
Other DBs
RHEA:
10183
LinkDB
All DBs
RCLASS: RC00026
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Entry
RC00026 RClass
Definition
N1b-N1c:*-C4a:C1b+C8y-C1b+C8y
Reactant pair
C00101_C00234
C00415_C03204
Related class
DB search
Reaction
R00941
R00943
R00944
R02238
R03940
R04325
R04560
R07660
R12790
Enzyme
1.5.1.6
2.1.2.2
2.1.2.3
2.1.2.9
2.1.2.13
2.1.2.14
3.5.1.10
6.3.4.3
6.3.4.17
Pathway
rn00670
One carbon pool by folate
rn00720
Other carbon fixation pathways
rn00970
Aminoacyl-tRNA biosynthesis
rn01100
Metabolic pathways
rn01120
Microbial metabolism in diverse environments
rn01200
Carbon metabolism
rn01240
Biosynthesis of cofactors
Orthology
K00288
methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetase [EC:
1.5.1.5
3.5.4.9
6.3.4.3
]
K00289
formyltetrahydrofolate dehydrogenase [EC:
1.5.1.6
]
K00601
phosphoribosylglycinamide formyltransferase [EC:
2.1.2.2
]
K00602
phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:
2.1.2.3
3.5.4.10
]
K00604
methionyl-tRNA formyltransferase [EC:
2.1.2.9
]
K00607
GDP-perosamine N-formyltransferase [EC:
2.1.2.14
]
K01433
formyltetrahydrofolate deformylase [EC:
3.5.1.10
]
K01492
phosphoribosylglycinamide/phosphoribosylaminoimidazolecarboxamide formyltransferase [EC:
2.1.2.2
2.1.2.3
]
K01938
formate--tetrahydrofolate ligase [EC:
6.3.4.3
]
K10011
UDP-4-amino-4-deoxy-L-arabinose formyltransferase / UDP-glucuronic acid dehydrogenase (UDP-4-keto-hexauronic acid decarboxylating) [EC:
2.1.2.13
1.1.1.305
]
K11175
phosphoribosylglycinamide formyltransferase 1 [EC:
2.1.2.2
]
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
K13402
monofunctional C1-tetrahydrofolate synthase, mitochondrial [EC:
6.3.4.3
]
DBGET
integrated database retrieval system