KEGG   REACTION: R00943
Entry
R00943                      Reaction                               
Name
formate:tetrahydrofolate ligase (ADP-forming)
Definition
Tetrahydrofolate + Formate + ATP <=> ADP + Orthophosphate + 10-Formyltetrahydrofolate
Equation
C00101 + C00058 + C00002 <=> C00008 + C00009 + C00234
Reaction class
RC00002  C00002_C00008
RC00026  C00101_C00234
RC00111  C00058_C00234
Enzyme
6.3.4.3
Pathway
rn00670  One carbon pool by folate
rn00720  Other carbon fixation pathways
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
rn01200  Carbon metabolism
rn01240  Biosynthesis of cofactors
Module
M00140  C1-unit interconversion, prokaryotes
M00141  C1-unit interconversion, eukaryotes
M00377  Reductive acetyl-CoA pathway (Wood-Ljungdahl pathway)
Brite
Enzymatic reactions [BR:br08201]
 6. Ligase reactions
  6.3  Forming carbon-nitrogen bonds
   6.3.4  Other carbon-nitrogen ligases
    6.3.4.3
     R00943  Tetrahydrofolate + Formate + ATP <=> ADP + Orthophosphate + 10-Formyltetrahydrofolate
Overall reaction [br08210.html]
 Carbon fixation
  R00943
Orthology
K00288  methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetase [EC:1.5.1.5 3.5.4.9 6.3.4.3]
K01938  formate--tetrahydrofolate ligase [EC:6.3.4.3]
K13402  monofunctional C1-tetrahydrofolate synthase, mitochondrial [EC:6.3.4.3]
Other DBs
RHEA: 20224
LinkDB

KEGG   RCLASS: RC00026
Entry
RC00026                     RClass                                 
Definition
N1b-N1c:*-C4a:C1b+C8y-C1b+C8y
Reactant pair
C00101_C00234    C00415_C03204
Related class
Reaction
R00941 R00943 R00944 R02238 R03940 R04325 R04560 R07660
R12790
Enzyme
1.5.1.6         2.1.2.2         2.1.2.3         2.1.2.9         
2.1.2.13        2.1.2.14        3.5.1.10        6.3.4.3         
6.3.4.17
Pathway
rn00670  One carbon pool by folate
rn00720  Other carbon fixation pathways
rn00970  Aminoacyl-tRNA biosynthesis
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
rn01200  Carbon metabolism
rn01240  Biosynthesis of cofactors
Orthology
K00288  methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetase [EC:1.5.1.5 3.5.4.9 6.3.4.3]
K00289  formyltetrahydrofolate dehydrogenase [EC:1.5.1.6]
K00601  phosphoribosylglycinamide formyltransferase [EC:2.1.2.2]
K00602  phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
K00604  methionyl-tRNA formyltransferase [EC:2.1.2.9]
K00607  GDP-perosamine N-formyltransferase [EC:2.1.2.14]
K01433  formyltetrahydrofolate deformylase [EC:3.5.1.10]
K01492  phosphoribosylglycinamide/phosphoribosylaminoimidazolecarboxamide formyltransferase [EC:2.1.2.2 2.1.2.3]
K01938  formate--tetrahydrofolate ligase [EC:6.3.4.3]
K10011  UDP-4-amino-4-deoxy-L-arabinose formyltransferase / UDP-glucuronic acid dehydrogenase (UDP-4-keto-hexauronic acid decarboxylating) [EC:2.1.2.13 1.1.1.305]
K11175  phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2]
K11787  phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.4.13 2.1.2.2 6.3.3.1]
K13402  monofunctional C1-tetrahydrofolate synthase, mitochondrial [EC:6.3.4.3]

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