KEGG   REACTION: R01838
Entry
R01838                      Reaction                               
Name
testosterone:NADP+ 17-oxidoreductase
Definition
Testosterone + NADP+ <=> Androstenedione + NADPH + H+
Equation
C00535 + C00006 <=> C00280 + C00005 + C00080
Comment
NAD+ (see R01836)
Reaction class
RC00001  C00005_C00006
RC00127  C00280_C00535
Enzyme
1.1.1.51        1.1.1.64
Pathway
rn00140  Steroid hormone biosynthesis
rn00984  Steroid degradation
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
Module
M00976  C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.51
     R01838  Testosterone + NADP+ <=> Androstenedione + NADPH + H+
    1.1.1.64
     R01838  Testosterone + NADP+ <=> Androstenedione + NADPH + H+
Orthology
K04119  aldo-keto reductase family 1 member C3 [EC:1.1.1.51 1.1.1.188 1.1.1.213 1.1.1.357]
K05296  3(or 17)beta-hydroxysteroid dehydrogenase [EC:1.1.1.51]
K10207  testosterone 17beta-dehydrogenase (NADP+) [EC:1.1.1.64]
Other DBs
RHEA: 14984
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