KEGG   REACTION: R01836
Entry
R01836                      Reaction                               
Name
testosterone:NAD+ 17-oxidoreductase
Definition
Testosterone + NAD+ <=> Androstenedione + NADH + H+
Equation
C00535 + C00003 <=> C00280 + C00004 + C00080
Comment
NADP+ (see R01838)
Reaction class
RC00001  C00003_C00004
RC00127  C00280_C00535
Enzyme
1.1.1.51        1.1.1.239
Pathway
rn00140  Steroid hormone biosynthesis
rn00984  Steroid degradation
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
Module
M00976  C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.51
     R01836  Testosterone + NAD+ <=> Androstenedione + NADH + H+
    1.1.1.239
     R01836  Testosterone + NAD+ <=> Androstenedione + NADH + H+
Orthology
K04119  aldo-keto reductase family 1 member C3 [EC:1.1.1.51 1.1.1.188 1.1.1.213 1.1.1.357]
K05296  3(or 17)beta-hydroxysteroid dehydrogenase [EC:1.1.1.51]
K13368  17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:1.1.1.62 1.1.1.239]
K13369  17beta-estradiol 17-dehydrogenase / all-trans-retinol dehydrogenase (NAD+) / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:1.1.1.62 1.1.1.105 1.1.1.239]
K13370  17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) / 3-oxoacyl-[acyl-carrier protein] reductase alpha subunit [EC:1.1.1.62 1.1.1.239]
Other DBs
RHEA: 14932
LinkDB

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