KEGG   REACTION: R04330
Entry
R04330                      Reaction                               
Name
androstan-3alpha,17beta-diol:NAD+ oxidoreductase
Definition
Androstan-3alpha,17beta-diol + NAD+ <=> Dihydrotestosterone + NADH + H+
Equation
C03852 + C00003 <=> C03917 + C00004 + C00080
Reaction class
RC00001  C00003_C00004
RC00144  C03852_C03917
Enzyme
1.1.1.53        1.1.1.239       1.1.1.357
Pathway
rn00140  Steroid hormone biosynthesis
rn01100  Metabolic pathways
Module
M00977  C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.53
     R04330  Androstan-3alpha,17beta-diol + NAD+ <=> Dihydrotestosterone + NADH + H+
    1.1.1.239
     R04330  Androstan-3alpha,17beta-diol + NAD+ <=> Dihydrotestosterone + NADH + H+
    1.1.1.357
     R04330  Androstan-3alpha,17beta-diol + NAD+ <=> Dihydrotestosterone + NADH + H+
IUBMB reaction hierarchy [BR:br08202]
 1. Oxidoreductase reactions
  1.1.1.357
   R10422  3alpha-Hydroxysteroid <=> 3-Oxosteroid
    R04330  Androstan-3alpha,17beta-diol <=> Dihydrotestosterone
Orthology
K00089  3alpha-hydroxysteroid 3-dehydrogenase [EC:1.1.1.213 1.1.1.357]
K13369  17beta-estradiol 17-dehydrogenase / all-trans-retinol dehydrogenase (NAD+) / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:1.1.1.62 1.1.1.105 1.1.1.239]
Other DBs
RHEA: 42007
LinkDB

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